A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin

Journal of Molecular Medicine

Volumn 86, Issue 4, 2008, Pages 457-469

  Verma, Navin K ^a   Dempsey, Eugene ^a   Conroy, Jennifer ^a   Olwell, Peter ^a   Mcelligott, Anthony M ^a   Davies, Anthony M ^a   Kelleher, Dermot ^a   Butini, Stefania ^b   Campiani, Giuseppe ^b   Williams, D Clive ^a   Zisterer, Daniela M ^a   Lawler, Mark ^a   Volkov, Yuri ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF SIENA   (Italy)

Author keywords

PBOX; T cell migration; Tubulin

Indexed keywords

4 ACETOXY 5 (1 NAPHTYL)NAPHTHO[2,3 B]PYRROLO[1,2 D][1,4]OXAZEPINE; BENZOXAZINE DERIVATIVE; INTEGRIN; PBOX 15; UNCLASSIFIED DRUG;

ARTICLE; CANCER CHEMOTHERAPY; CELL ISOLATION; CELL MIGRATION; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; DRUG TARGETING; HUMAN; HUMAN CELL; LYMPHOCYTE MIGRATION; LYMPHOMA CELL LINE; METASTASIS INHIBITION; MICROTUBULE; MICROTUBULE ASSEMBLY; MOLECULAR DYNAMICS; MOLECULAR THERAPY; PROTEIN CROSS LINKING; PROTEIN PROCESSING; T CELL LYMPHOMA; T LYMPHOCYTE;

APOPTOSIS; CELL LINE, TUMOR; CELL MOVEMENT; HUMANS; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MICROTUBULES; OXAZEPINES; PHENOTYPE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PYRROLES; T-LYMPHOCYTES; TUBULIN; TUBULIN MODULATORS;

EID: 42449146511     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-008-0312-8     Document Type: Article

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