Manganese enhanced magnetic resonance imaging in a contusion model of spinal cord injury in rats: Correlation with motor function

Investigative Radiology

Volumn 43, Issue 5, 2008, Pages 277-283

  Walder, Nadja ^a   Petter Puchner, Alexander H ^a,b   Brejnikow, Mika ^a   Redl, Heinz ^a   Essig, Marco ^c   Stieltjes, Bram ^c  

^a LUDWIG BOLTZMANN INSTITUTE FOR EXPERIMENTAL AND CLINICAL TRAUMATOLOGY   (Austria)

^b AUSTRIAN CLUSTER FOR TISSUE REGENERATION   (Austria)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

BBB; Correlation; Magnetic resonance imaging (MRI); Manganese; Spinal cord injury (SCI)

Indexed keywords

MAGNESIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CISTERNA MAGNA; CONTRAST ENHANCEMENT; CONTROLLED STUDY; CONTUSION; EXPERIMENTAL MODEL; FUNCTIONAL ASSESSMENT; HISTOLOGY; LOCOMOTION; MALE; MOTOR PERFORMANCE; NEUROIMAGING; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY; VERTEBRA;

EID: 42449142417     PISSN: 00209996     EISSN: None     Source Type: Journal    
DOI: 10.1097/RLI.0b013e318162f1bd     Document Type: Article

References (25)

1. Rosenzweig ES, McDonald JW. Rodent models for treatment of spinal cord injury: research trends and progress toward useful repair. Curr Opin Neurol. 2004;17:121-131.
2. Kwon BK, Oxland TR, Tetzlaff W. Animal models used in spinal cord regeneration research. Spine. 2002;27:1504-1510.
3. McEwen ML, Springer JE. Quantification of locomotor recovery following spinal cord contusion in adult rats. J Neurotrauma. 2006;23:1632-1653.
4. Basso DM, Beattie MS, Bresnahan JC. A sensitive and reliable locomotor rating scale for open field testing in rats. J Neurotrauma. 1995;12:1-21.
5. Rivlin AS, Tator CH. Objective clinical assessment of motor function after experimental spinal cord injury in the rat. J Neurosurg. 1977;47:577-581.
6. Stieltjes B, Klussmann S, Bock M, et al. Manganese-enhanced magnetic resonance imaging for in vivo assessment of damage and functional improvement following spinal cord injury in mice. Magn Reson Med. 2006;55:1124-1131.
7. Slucky AV, Potter HG. Use of magnetic resonance imaging in spinal trauma: indications, techniques, and utility. J Am Acad Orthop Surg. 1998;6:134-145.
8. Aoki I, Wu YJ, Silva AC, et al. In vivo detection of neuroarchitecture in the rodent brain using manganese-enhanced MRI. Neuroimage. 2004;22:1046-1059.
9. Van der Linden A, Verhoye M, Van Meir V, et al. In vivo manganese-enhanced magnetic resonance imaging reveals connections and functional properties of the songbird vocal control system. Neuroscience. 2002;112:467-474.
10. Saleem KS, Pauls JM, Augath M, et al. Magnetic resonance imaging of neuronal connections in the macaque monkey. Neuron. 2002;34:685-700.
11. Watanabe T, Michaelis T, Frahm J. Mapping of retinal projections in the living rat using high-resolution 3D gradient-echo MRI with Mn2+-induced contrast. Magn Reson Med. 2001;46:424-429.
12. Scheff SW, Rabchevsky AG, Fugaccia I, et al. Experimental modeling of spinal cord injury: characterization of a force-defined injury device. J Neurotrauma. 2003;20:179-193.
13. John JP, Pintsov O, Petter-Puchner A, et al. Nitric oxide and oxygen radical attack on GDP-dissociation inhibitor 2 (GDI-2) in spinal cord injury of the rat. J Proteome Res. 2007;6:1500-1509.
14. Schuler P, Oyanguren H, Maturana V, et al. Manganese poisoning; environmental and medical study at a Chilean mine. Ind Med Surg. 1957;26:167-173.
15. Deppe M, Duning T, Mohammadi S, et al. Diffusion-tensor imaging at 3 T: detection of white matter alterations in neurological patients on the basis of normal values. Invest Radiol. 2007;42:338-345.
16. Jansen JF, Kooi ME, Kessels AG, et al. Reproducibility of quantitative cerebral T2 relaxometry, diffusion tensor imaging, and 1H magnetic resonance spectroscopy at 3. 0 Tesla. Invest Radiol. 2007;42:327-337.
17. Ellingson BM, Ulmer JL, Schmit BD. Optimal diffusion tensor indices for imaging the human spinal cord. Biomed Sci Instrum. 2007;43:128-133.
18. Loy DN, Kim JH, Xie M, et al. Diffusion tensor imaging predicts hyperacute spinal cord injury severity. J Neurotrauma. 2007;24:979-990.
19. Pautler RG, Silva AC, Koretsky AP. In vivo neuronal tract tracing using manganese-enhanced magnetic resonance imaging. Magn Reson Med. 1998;40:740-748.
20. Pautler RG, Mongeau R, Jacobs RE. In vivo trans-synaptic tract tracing from the murine striatum and amygdala utilizing manganese enhanced MRI (MEMRI). Magn Reson Med. 2003;50:33-39.
21. Leergaard TB, Bjaalie JG, Devor A, et al. In vivo tracing of major rat brain pathways using manganese-enhanced magnetic resonance imaging and three-dimensional digital atlasing. Neuroimage. 2003;20:1591-1600.
22. Lin YJ, Koretsky AP. Manganese ion enhances T1-weighted MRI during brain activation: an approach to direct imaging of brain function. Magn Reson Med. 1997;38:378-388.
23. Bilgen M, Dancause N, Al-Hafez B, et al. Manganese-enhanced MRI of rat spinal cord injury. Magn Reson Imaging. 2005;23:829-832.
24. Liu XZ, Xu XM, Hu R, et al. Neuronal and glial apoptosis after traumatic spinal cord injury. J Neurosci. 1997;17:5395-5406.
25. Carlson SL, Parrish ME, Springer JE, et al. Acute inflammatory response in spinal cord following impact injury. Exp Neurol. 1998;151:77-88.