A novel cell death pathway that is partially caspase dependent, but morphologically non-apoptotic, elicited by proteasomal inhibition of rat sympathetic neurons

Journal of Neurochemistry

Volumn 105, Issue 3, 2008, Pages 653-665

  Lang Rollin, Isabelle ^a   Dermentzaki, Georgia ^b   Vekrellis, Kostas ^b   Xilouri, Maria ^b   Rideout, Hardy J ^a   Stefanis, Leonidas ^a,b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b BIOMEDICAL RESEARCH FOUNDATION   (Greece)

Author keywords

Autophagy; Bim; Caspase 3 independent; Neurodegeneration; Protein degradation

Indexed keywords

3 METHYLADENINE; BIM PROTEIN; BOC ASPARTYL FLUOROMETHYLKETONE; CASPASE 3; CASPASE INHIBITOR; CYTOCHROME C; NERVE GROWTH FACTOR; PROTEASOME; PROTEIN BCL XL; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGY; CELL DEATH; CELL FUNCTION; CONTROLLED STUDY; MITOCHONDRION; MOUSE; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SYMPATHETIC NERVE CELL;

ADENINE; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BCL-X PROTEIN; CASPASES; CELL DEATH; CELL SHAPE; CELLS, CULTURED; ENZYME ACTIVATION; ENZYME INHIBITORS; GANGLIA, SYMPATHETIC; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NEURONS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTO-ONCOGENE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY;

RATTUS;

EID: 42449109583     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.05165.x     Document Type: Article

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