-
1
-
-
34248136340
-
Inflammatory bowel disease: Clinical aspects and established and evolving therapies
-
Baumgart DC, Sandborn WJ. Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet. 2007;369:1641-1657.
-
(2007)
Lancet
, vol.369
, pp. 1641-1657
-
-
Baumgart, D.C.1
Sandborn, W.J.2
-
2
-
-
34248136828
-
Inflammatory bowel disease: Cause and immunobiology
-
Baumgart DC, Carding SR. Inflammatory bowel disease: cause and immunobiology. Lancet. 2007;369:1627-1640.
-
(2007)
Lancet
, vol.369
, pp. 1627-1640
-
-
Baumgart, D.C.1
Carding, S.R.2
-
3
-
-
0036395918
-
Understanding immune-microbial homeostasis in intestine
-
Elson CO, Cong Y. Understanding immune-microbial homeostasis in intestine. Immunol Res. 2002;26:87-94.
-
(2002)
Immunol Res
, vol.26
, pp. 87-94
-
-
Elson, C.O.1
Cong, Y.2
-
4
-
-
0036107919
-
Immunoregulation in the gut: Success and failures in human disease
-
Monteleone I, Vavassori P, Biancone L, et al. Immunoregulation in the gut: success and failures in human disease. Gut. 2002;50(suppl 3):III60-64.
-
(2002)
Gut
, vol.50
, Issue.SUPPL. 3
-
-
Monteleone, I.1
Vavassori, P.2
Biancone, L.3
-
5
-
-
0034013615
-
Pathways of T cell pathology in models of chronic intestinal inflammation
-
Simpson SJ, de Jong YP, Comiskey M, et al. Pathways of T cell pathology in models of chronic intestinal inflammation. Int Rev Immunol. 2000;19:1-37.
-
(2000)
Int Rev Immunol
, vol.19
, pp. 1-37
-
-
Simpson, S.J.1
de Jong, Y.P.2
Comiskey, M.3
-
7
-
-
22544465538
-
A theoretical framework for quantitative analysis of the molecular basis of costimulation
-
Jansson A, Barnes E, Klenerman P, et al. A theoretical framework for quantitative analysis of the molecular basis of costimulation. J Immunol. 2005;175:1575-1585.
-
(2005)
J Immunol
, vol.175
, pp. 1575-1585
-
-
Jansson, A.1
Barnes, E.2
Klenerman, P.3
-
8
-
-
0042971650
-
Molecular interactions mediating T cell antigen recognition
-
Van Der Merwe PA, Davis SJ. Molecular interactions mediating T cell antigen recognition. Annu Rev Immunol. 2003;21:659-684.
-
(2003)
Annu Rev Immunol
, vol.21
, pp. 659-684
-
-
Van Der Merwe, P.A.1
Davis, S.J.2
-
10
-
-
0033364347
-
T-cell co-stimulatory molecules are upregulated on intestinal macrophages from inflammatory bowel disease mucosa
-
Rogler G, Hausmann M, Spottl T, et al. T-cell co-stimulatory molecules are upregulated on intestinal macrophages from inflammatory bowel disease mucosa. Eur J Gastroenterol Hepatol. 1999;11:1105-1111.
-
(1999)
Eur J Gastroenterol Hepatol
, vol.11
, pp. 1105-1111
-
-
Rogler, G.1
Hausmann, M.2
Spottl, T.3
-
11
-
-
0030763573
-
Differential distribution of B7.1 (CD80) and B7.2 (CD86) costimulatory molecules on mucosal macrophage subsets in human inflammatory bowel disease (IBD)
-
Rugtveit J, Bakka A, Brandtzaeg P. Differential distribution of B7.1 (CD80) and B7.2 (CD86) costimulatory molecules on mucosal macrophage subsets in human inflammatory bowel disease (IBD). Clin Exp Immunol. 1997;110:104-113.
-
(1997)
Clin Exp Immunol
, vol.110
, pp. 104-113
-
-
Rugtveit, J.1
Bakka, A.2
Brandtzaeg, P.3
-
12
-
-
0035523197
-
Expression of B7 costimulatory molecules by cells infiltrating the colon in experimental colitis induced by oral dextran sulfate sodium in the mouse
-
Grose RH, Howarth GS, Xian CJ, et al. Expression of B7 costimulatory molecules by cells infiltrating the colon in experimental colitis induced by oral dextran sulfate sodium in the mouse. J Gastroenterol Hepatol. 2001;16:1228-1234.
-
(2001)
J Gastroenterol Hepatol
, vol.16
, pp. 1228-1234
-
-
Grose, R.H.1
Howarth, G.S.2
Xian, C.J.3
-
13
-
-
0033950079
-
The importance of being proline: The interaction of proline-rich motifs in signaling proteins with their cognate domains
-
Kay BK, Williamson MP, Sudol M. The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains. FASEB J. 2000;14:231-241.
-
(2000)
FASEB J
, vol.14
, pp. 231-241
-
-
Kay, B.K.1
Williamson, M.P.2
Sudol, M.3
-
14
-
-
0034721737
-
Structure of murine CTLA-4 and its role in modulating T cell responsiveness
-
Ostrov DA, Shi W, Schwartz JC, et al. Structure of murine CTLA-4 and its role in modulating T cell responsiveness. Science. 2000;290:816-819.
-
(2000)
Science
, vol.290
, pp. 816-819
-
-
Ostrov, D.A.1
Shi, W.2
Schwartz, J.C.3
-
15
-
-
0035967146
-
Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses
-
Stamper CC, Zhang Y, Tobin JF, et al. Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses. Nature. 2001;410:608-611.
-
(2001)
Nature
, vol.410
, pp. 608-611
-
-
Stamper, C.C.1
Zhang, Y.2
Tobin, J.F.3
-
16
-
-
15444379995
-
CD80 binding polyproline helical peptide inhibits T cell activation
-
Srinivasan M, Lu D, Eri R, et al. CD80 binding polyproline helical peptide inhibits T cell activation. J Biol Chem. 2005;280:10149-10155.
-
(2005)
J Biol Chem
, vol.280
, pp. 10149-10155
-
-
Srinivasan, M.1
Lu, D.2
Eri, R.3
-
17
-
-
33847070378
-
Suppression of immune responses in collagen-induced arthritis by a rationally designed CD80-binding peptide agent
-
Srinivasan M, Eri R, Zunt SL, et al. Suppression of immune responses in collagen-induced arthritis by a rationally designed CD80-binding peptide agent. Arthritis Rheum. 2007;56:498-508.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 498-508
-
-
Srinivasan, M.1
Eri, R.2
Zunt, S.L.3
-
18
-
-
0035425004
-
B7 interactions with CD28 and CTLA-4 control tolerance or induction of mucosal inflammation in chronic experimental colitis
-
Liu Z, Geboes K, Hellings P, et al. B7 interactions with CD28 and CTLA-4 control tolerance or induction of mucosal inflammation in chronic experimental colitis. J Immunol. 2001;167:1830-1838.
-
(2001)
J Immunol
, vol.167
, pp. 1830-1838
-
-
Liu, Z.1
Geboes, K.2
Hellings, P.3
-
20
-
-
33750949170
-
Interleukin-1 beta-induced anorexia is reversed by ghrelin
-
Gonzalez PV, Cragnolini AB, Schioth HB, et al. Interleukin-1 beta-induced anorexia is reversed by ghrelin. Peptides. 2006;27:3220-3225.
-
(2006)
Peptides
, vol.27
, pp. 3220-3225
-
-
Gonzalez, P.V.1
Cragnolini, A.B.2
Schioth, H.B.3
-
21
-
-
0032921746
-
A synthetic mimetic of CD4 is able to suppress disease in a rodent model of immune colitis
-
Okamoto S, Watanabe M, Yamazaki M, et al. A synthetic mimetic of CD4 is able to suppress disease in a rodent model of immune colitis. Eur J Immunol. 1999;29:355-366.
-
(1999)
Eur J Immunol
, vol.29
, pp. 355-366
-
-
Okamoto, S.1
Watanabe, M.2
Yamazaki, M.3
-
22
-
-
0030978915
-
Bioactive peptide design based on protein surface epitopes. A cyclic heptapeptide mimics CD4 domain 1 CC loop and inhibits CD4 biological function
-
Satoh T, Aramini JM, Li S, et al. Bioactive peptide design based on protein surface epitopes. A cyclic heptapeptide mimics CD4 domain 1 CC loop and inhibits CD4 biological function. J Biol Chem. 1997;272:12175-12180.
-
(1997)
J Biol Chem
, vol.272
, pp. 12175-12180
-
-
Satoh, T.1
Aramini, J.M.2
Li, S.3
-
23
-
-
0037103157
-
Suppression of experimental autoimmune encephalomyelitis using peptide mimics of CD28
-
Srinivasan M, Gienapp IE, Stuckman SS, et al. Suppression of experimental autoimmune encephalomyelitis using peptide mimics of CD28. J Immunol. 2002;169:2180-2188.
-
(2002)
J Immunol
, vol.169
, pp. 2180-2188
-
-
Srinivasan, M.1
Gienapp, I.E.2
Stuckman, S.S.3
-
24
-
-
20244372724
-
Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis
-
Fukata M, Michelsen KS, Eri R, et al. Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis. Am J Physiol Gastrointest Liver Physiol. 2005;288:G1055-1065.
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.288
-
-
Fukata, M.1
Michelsen, K.S.2
Eri, R.3
-
25
-
-
10044282950
-
Assessment of T-cell clonality via T-cell receptor-gamma rearrangements in cutaneous T-cell-dominant infiltrates using polymerase chain reaction and single-stranded DNA conformational polymorphism assay
-
Chen M, Deng A, Crowson AN, et al. Assessment of T-cell clonality via T-cell receptor-gamma rearrangements in cutaneous T-cell-dominant infiltrates using polymerase chain reaction and single-stranded DNA conformational polymorphism assay. Appl Immunohistochem Mol Morphol. 2004;12:373-379.
-
(2004)
Appl Immunohistochem Mol Morphol
, vol.12
, pp. 373-379
-
-
Chen, M.1
Deng, A.2
Crowson, A.N.3
-
26
-
-
18244372722
-
Therapeutic effect of the immunomodulator glatiramer acetate on trinitrobenzene sulfonic acid-induced experimental colitis
-
Aharoni R, Kayhan B, Arnon R. Therapeutic effect of the immunomodulator glatiramer acetate on trinitrobenzene sulfonic acid-induced experimental colitis. Inflamm Bowel Dis. 2005;11:106-115.
-
(2005)
Inflamm Bowel Dis
, vol.11
, pp. 106-115
-
-
Aharoni, R.1
Kayhan, B.2
Arnon, R.3
-
27
-
-
14944365560
-
Therapeutic potential of follistatin for colonic inflammation in mice
-
Dohi T, Ejima C, Kato R, et al. Therapeutic potential of follistatin for colonic inflammation in mice. Gastroenterology. 2005;128:411-423.
-
(2005)
Gastroenterology
, vol.128
, pp. 411-423
-
-
Dohi, T.1
Ejima, C.2
Kato, R.3
-
28
-
-
0035478848
-
Molecular cloning of F4/80-like-receptor, a seven-span membrane protein expressed differentially by dendritic cell and monocyte-macrophage subpopulations
-
Caminschi I, Lucas KM, O'Keeffe MA, et al. Molecular cloning of F4/80-like-receptor, a seven-span membrane protein expressed differentially by dendritic cell and monocyte-macrophage subpopulations. J Immunol. 2001;167:3570-3576.
-
(2001)
J Immunol
, vol.167
, pp. 3570-3576
-
-
Caminschi, I.1
Lucas, K.M.2
O'Keeffe, M.A.3
-
29
-
-
0037474541
-
Structural characterisation and functional significance of transient protein-protein interactions
-
Nooren IM, Thornton JM. Structural characterisation and functional significance of transient protein-protein interactions. J Mol Biol. 2003;325:991-1018.
-
(2003)
J Mol Biol
, vol.325
, pp. 991-1018
-
-
Nooren, I.M.1
Thornton, J.M.2
-
30
-
-
3142781225
-
Small-molecule inhibitors of protein-protein interactions: Progressing towards the dream
-
Arkin MR, Wells JA. Small-molecule inhibitors of protein-protein interactions: progressing towards the dream. Nat Rev. 2004;3:301-317.
-
(2004)
Nat Rev
, vol.3
, pp. 301-317
-
-
Arkin, M.R.1
Wells, J.A.2
-
31
-
-
0030809003
-
The role of PU conformations in the calculation of peptide fractional helix content
-
Park SH, Shalongo W, Stellwagen E. The role of PU conformations in the calculation of peptide fractional helix content. Protein Sci. 1997;6:1694-1700.
-
(1997)
Protein Sci
, vol.6
, pp. 1694-1700
-
-
Park, S.H.1
Shalongo, W.2
Stellwagen, E.3
-
32
-
-
0037160094
-
Circular dichroism and nuclear magnetic resonance spectroscopic analysis of immunogenic gluten peptides and their analogs
-
Parrot I, Huang PC, Khosla C. Circular dichroism and nuclear magnetic resonance spectroscopic analysis of immunogenic gluten peptides and their analogs. J Biol Chem. 2002;277:45572-45578.
-
(2002)
J Biol Chem
, vol.277
, pp. 45572-45578
-
-
Parrot, I.1
Huang, P.C.2
Khosla, C.3
-
33
-
-
0034852066
-
Structural biology of T-cell costimulatory proteins: New insights, more surprises
-
Bajorath J. Structural biology of T-cell costimulatory proteins: New insights, more surprises. J Mol Graph Model. 2001;19:619-623.
-
(2001)
J Mol Graph Model
, vol.19
, pp. 619-623
-
-
Bajorath, J.1
-
34
-
-
34247646491
-
Paradoxical effect of reduced costimulation in T cell-mediated colitis
-
Kim G, Levin M, Schoenberger SP, et al. Paradoxical effect of reduced costimulation in T cell-mediated colitis. J Immunol. 2007;178:5563-5570.
-
(2007)
J Immunol
, vol.178
, pp. 5563-5570
-
-
Kim, G.1
Levin, M.2
Schoenberger, S.P.3
-
35
-
-
33749343778
-
Critical appraisal of the current practice in murine TNBS-induced colitis
-
te Velde AA, Verstege MI, Hommes DW. Critical appraisal of the current practice in murine TNBS-induced colitis. Inflamm Bowel Dis. 2006;12:995-999.
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 995-999
-
-
te Velde, A.A.1
Verstege, M.I.2
Hommes, D.W.3
-
36
-
-
0028949152
-
B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
-
Kuchroo VK, Das MP, Brown JA, et al. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell. 1995;80:707-718.
-
(1995)
Cell
, vol.80
, pp. 707-718
-
-
Kuchroo, V.K.1
Das, M.P.2
Brown, J.A.3
-
37
-
-
0033179230
-
Blockade of CD28 during in vitro activation of encephalitogenic T cells or after disease onset ameliorates experimental autoimmune encephalomyelitis
-
Perrin PJ, June CH, Maldonado JH, et al. Blockade of CD28 during in vitro activation of encephalitogenic T cells or after disease onset ameliorates experimental autoimmune encephalomyelitis. J Immunol. 1999;163:1704-1710.
-
(1999)
J Immunol
, vol.163
, pp. 1704-1710
-
-
Perrin, P.J.1
June, C.H.2
Maldonado, J.H.3
-
38
-
-
10844272960
-
Small therapeutic molecules for the treatment of inflammatory bowel disease
-
van Deventer SJ. Small therapeutic molecules for the treatment of inflammatory bowel disease. Gut. 2002;50(Suppl 3):III47-53.
-
(2002)
Gut
, vol.50
, Issue.SUPPL. 3
-
-
van Deventer, S.J.1
-
39
-
-
18144368957
-
Immunomodulatory peptides from IgSF proteins: A review
-
Srinivasan M, Roeske RW. Immunomodulatory peptides from IgSF proteins: a review. Curr Protein Pept Sci. 2005;6:185-196.
-
(2005)
Curr Protein Pept Sci
, vol.6
, pp. 185-196
-
-
Srinivasan, M.1
Roeske, R.W.2
-
40
-
-
33749018842
-
Synergistic costimulation by both B7 molecules regulates colitis pathogenesis
-
Kim G, Schoenberger SP, Sharpe A, et al. Synergistic costimulation by both B7 molecules regulates colitis pathogenesis. Ann N Y Acad Sci. 2006;1072:233-241.
-
(2006)
Ann N Y Acad Sci
, vol.1072
, pp. 233-241
-
-
Kim, G.1
Schoenberger, S.P.2
Sharpe, A.3
-
41
-
-
0032874717
-
Functional expression of costimulatory molecule CD86 on epithelial cells in the inflamed colonic mucosa
-
Nakazawa A, Watanabe M, Kanai T, et al. Functional expression of costimulatory molecule CD86 on epithelial cells in the inflamed colonic mucosa. Gastroenterology. 1999;117:536-545.
-
(1999)
Gastroenterology
, vol.117
, pp. 536-545
-
-
Nakazawa, A.1
Watanabe, M.2
Kanai, T.3
-
42
-
-
34047186008
-
T cell costimulation: A rational target in the therapeutic armamentarium for autoimmune diseases and transplantation
-
Vincenti F, Luggen M. T cell costimulation: a rational target in the therapeutic armamentarium for autoimmune diseases and transplantation. Annu Rev Med. 2007;58:347-358.
-
(2007)
Annu Rev Med
, vol.58
, pp. 347-358
-
-
Vincenti, F.1
Luggen, M.2
-
43
-
-
0033485666
-
The differentiated state of intestinal lamina propria CD4+ T cells results in altered cytokine production, activation threshold, and costimulatory requirements
-
Hurst SD, Cooper CJ, Sitterding SM, et al. The differentiated state of intestinal lamina propria CD4+ T cells results in altered cytokine production, activation threshold, and costimulatory requirements. J Immunol. 1999;163:5937-5945.
-
(1999)
J Immunol
, vol.163
, pp. 5937-5945
-
-
Hurst, S.D.1
Cooper, C.J.2
Sitterding, S.M.3
-
44
-
-
0033027828
-
Modulation of experimental blood stage malaria through blockade of the B7/CD28 T-cell costimulatory pathway
-
Taylor-Robinson AW, Smith EC. Modulation of experimental blood stage malaria through blockade of the B7/CD28 T-cell costimulatory pathway. Immunology. 1999;96:498-504.
-
(1999)
Immunology
, vol.96
, pp. 498-504
-
-
Taylor-Robinson, A.W.1
Smith, E.C.2
-
45
-
-
0029073090
-
Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation?
-
Thompson CB. Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation? Cell. 1995;81:979-982.
-
(1995)
Cell
, vol.81
, pp. 979-982
-
-
Thompson, C.B.1
-
46
-
-
0028863237
-
Critical role of CD28/B7 costimulation in the development of human Th2 cytokine-producing cells
-
Webb LM, Feldmann M. Critical role of CD28/B7 costimulation in the development of human Th2 cytokine-producing cells. Blood. 1995;86:3479-3486.
-
(1995)
Blood
, vol.86
, pp. 3479-3486
-
-
Webb, L.M.1
Feldmann, M.2
-
47
-
-
0030787528
-
Expression of costimulatory molecules B7-1 and B7-2 in macrophages and granulomas of Crohn's disease: Demonstration of cell-to-cell contact with T lymphocytes
-
Hara J, Ohtani H, Matsumoto T, et al. Expression of costimulatory molecules B7-1 and B7-2 in macrophages and granulomas of Crohn's disease: demonstration of cell-to-cell contact with T lymphocytes. Lab Invest. 1997;77:175-184.
-
(1997)
Lab Invest
, vol.77
, pp. 175-184
-
-
Hara, J.1
Ohtani, H.2
Matsumoto, T.3
-
48
-
-
0037326647
-
Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice
-
Watanabe N, Ikuta K, Okazaki K, et al. Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice. Dig Dis Sci. 2003;48:408-414.
-
(2003)
Dig Dis Sci
, vol.48
, pp. 408-414
-
-
Watanabe, N.1
Ikuta, K.2
Okazaki, K.3
-
49
-
-
0037033434
-
T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitis
-
Iqbal N, Oliver JR, Wagner FH, et al. T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitis. J Exp Med. 2002;195:71-84.
-
(2002)
J Exp Med
, vol.195
, pp. 71-84
-
-
Iqbal, N.1
Oliver, J.R.2
Wagner, F.H.3
-
50
-
-
33846497525
-
B7-deficient autoreactive T cells are highly susceptible to suppression by CD4(+)CD25(+) regulatory T cells
-
May KF, Jr., Chang X, Zhang H, et al. B7-deficient autoreactive T cells are highly susceptible to suppression by CD4(+)CD25(+) regulatory T cells. J Immunol. 2007;178:1542-1552.
-
(2007)
J Immunol
, vol.178
, pp. 1542-1552
-
-
May Jr., K.F.1
Chang, X.2
Zhang, H.3
-
51
-
-
0033214997
-
Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide stimulate the induction of Th2 responses by up-regulating B7.2 expression
-
Delgado M, Leceta J, Gomariz RP, et al. Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide stimulate the induction of Th2 responses by up-regulating B7.2 expression. J Immunol. 1999;163:3629-3635.
-
(1999)
J Immunol
, vol.163
, pp. 3629-3635
-
-
Delgado, M.1
Leceta, J.2
Gomariz, R.P.3
-
52
-
-
14644414825
-
New insights into the molecular mechanism of interleukin-10-mediated immunosuppression
-
Grutz G. New insights into the molecular mechanism of interleukin-10-mediated immunosuppression. J Leukoc Biol. 2005;77:3-15.
-
(2005)
J Leukoc Biol
, vol.77
, pp. 3-15
-
-
Grutz, G.1
-
53
-
-
33645023639
-
Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: The role of T regulatory cells
-
Taylor A, Verhagen J, Blaser K, et al. Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells. Immunology. 2006;117:433-442.
-
(2006)
Immunology
, vol.117
, pp. 433-442
-
-
Taylor, A.1
Verhagen, J.2
Blaser, K.3
-
54
-
-
12744269337
-
Tolerizing effects of co-stimulation blockade rest on functional dominance of CD4+CD25+ regulatory T cells
-
Coenen JJ, Koenen HJ, van Rijssen E, et al. Tolerizing effects of co-stimulation blockade rest on functional dominance of CD4+CD25+ regulatory T cells. Transplantation. 2005;79:147-156.
-
(2005)
Transplantation
, vol.79
, pp. 147-156
-
-
Coenen, J.J.1
Koenen, H.J.2
van Rijssen, E.3
-
55
-
-
12344307563
-
Conversion of CD4+ CD25- cells into CD4+ CD25+ regulatory T cells in vivo requires B7 costimulation, but not the thymus
-
Liang S, Alard P, Zhao Y, et al. Conversion of CD4+ CD25- cells into CD4+ CD25+ regulatory T cells in vivo requires B7 costimulation, but not the thymus. J Exp Med. 2005;201:127-137.
-
(2005)
J Exp Med
, vol.201
, pp. 127-137
-
-
Liang, S.1
Alard, P.2
Zhao, Y.3
|