Cytokeratin-RNA cross-linking mediated by the antitumor aminoflavone, 5-amino-2,3-fluorophenyl-6,8-difluoro-7-methyl-4H-1-benzopyran-4-one

Journal of Pharmacology and Experimental Therapeutics

Volumn 325, Issue 2, 2008, Pages 674-680

  Meng, Ling Hua ^a,c   Meng, Zhaojing ^b   Miao, Ze Hong ^a,c   Veenstra, Timothy D ^b   Pommier, Yves ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

^c SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 2,3 FLUOROPHENYL 6,8 DIFLUORO 7 METHYL 4H 1 BENZOPYRAN 4 ONE; ANTINEOPLASTIC AGENT; CYTOKERATIN; CYTOKERATIN ANTIBODY; ELONGATION FACTOR; HEAT SHOCK PROTEIN; MESSENGER RNA; NUCLEIC ACID BINDING PROTEIN; RIBONUCLEASE A; RNA; UNCLASSIFIED DRUG; 5 AMINO 6,8 DIFLUORO 2 (3 FLUOROPHENYL) 7 METHYL 4H 1 BENZOPYRAN 4 ONE; DNA; FLAVONOID; KERATIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CROSS LINKING; DRUG INHIBITION; DRUG MECHANISM; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SYNTHESIS; METABOLISM; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DNA; FLAVONOIDS; HUMANS; KERATINS; RNA;

EID: 42449092509     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.137802     Document Type: Article

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