The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 8, 2008, Pages 4661-4669

  Parker, Matthew A ^a   Kurrasch, Deborah M ^a   Nichols, David E ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

5 HT2A receptor; Binding affinity; Functional activity; Lipophilicity

Indexed keywords

SEROTONIN 2A RECEPTOR;

ARTICLE; BINDING AFFINITY; BROMINATION; CORRELATION ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPOPHILICITY; NUCLEAR MAGNETIC RESONANCE; RECEPTOR BINDING;

ANTHRACENES; CATALYSIS; HYDROPHOBICITY; LIGANDS; LIPIDS; MOLECULAR STRUCTURE; PHENETHYLAMINES; PROTEIN BINDING; RECEPTOR, SEROTONIN, 5-HT2A; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS;

EID: 42149195403     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.02.033     Document Type: Article

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