Dihydrobenzofuran analogues of hallucinogens. 3. Models of 4-substituted (2,5-dimethoxyphenyl)alkylamine derivatives with rigidified methoxy groups

Journal of Medicinal Chemistry

Volumn 39, Issue 15, 1996, Pages 2953-2961

  Monte, Aaron P ^a,c   Marona Lewicka, Danuta ^a   Parker, Matthew A ^a   Wainscott, David B ^b   Nelson, David L ^b   Nichols, David E ^a  

^a PURDUE UNIVERSITY   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c UNIVERSITY OF WISCONSIN LA CROSSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (8 BROMO 2,3,6,7 TETRAHYDROBENZO[1,2 B:4,5 B']DIFURAN 4 YL) 2 AMINOPROPANE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; CINANSERIN; DIHYDROBENZOFURAN DERIVATIVE; KETANSERIN; LYSERGIDE; MESULERGINE; PHENETHYLAMINE DERIVATIVE; PHENYLALKYLAMINE; PSYCHEDELIC AGENT; RAUWOLSCINE; SEROTONIN 1A RECEPTOR; SEROTONIN 1C RECEPTOR; SEROTONIN 2A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG CONFORMATION; DRUG DISCRIMINATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HUMAN; NONHUMAN; RAT; RECEPTOR AFFINITY; SEROTONINERGIC SYSTEM; STRUCTURE ACTIVITY RELATION;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; BEHAVIOR, ANIMAL; BENZOFURANS; BINDING, COMPETITIVE; CELL MEMBRANE; CRICETINAE; HALLUCINOGENS; HIPPOCAMPUS; HUMANS; KETANSERIN; LYSERGIC ACID DIETHYLAMIDE; MALE; MESOCRICETUS; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; STRUCTURE-ACTIVITY RELATIONSHIP; TRITIUM;

EID: 0029898995     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960199j     Document Type: Article

References (44)

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