Novel hydrophilic drug polymer nano-conjugates of cisplatin showing long blood retention profile - Its release kinetics, cellular uptake and bio-distribution

Current Drug Delivery

Volumn 5, Issue 2, 2008, Pages 120-126

  Verma, Anita K ^a   Sachin, K ^a  

^a UNIVERSITY OF DELHI   (India)

Author keywords

Bio distribution; Cell uptake; Nano conjugates; Pectin cisplatin; Pharmacokinetics; Zeta potential

Indexed keywords

CISPLATIN; FLUORESCEIN ISOTHIOCYANATE; PECTIN; POLYMER;

ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; CELL ADHESION; CIRCULATION; CONTROLLED STUDY; DRUG BINDING; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG RELEASE; DRUG RETENTION; FEMALE; HYDROPHILICITY; IMMUNOFLUORESCENCE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET SPECTROSCOPY; ZETA POTENTIAL;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; BLOOD PROTEINS; CELL LINE; CISPLATIN; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; FEMALE; HYDROPHOBICITY; LIGHT; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PECTINS; SCATTERING, RADIATION; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 42149130902     PISSN: 15672018     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720108783954806     Document Type: Article

References (32)

1. Ringsdorf, H. J. Polym. Sci. Polym. Symp., 1975, 51, 135.
2. Duncan, R.; Kopecek, J. Adv. Polym. Sci., 1984, 57, 51.
3. Duncan, R. Anti Cancer Drugs, 1992, 3, 175.
4. Duncan, R. Polymer-drug conjugates. In Handbook of Anticancer Drug Development, By Budman, D.; Calvert, H.; Rowinsky, E. Eds.; Lippincott, Williams & Wilkins: Philadelphia, USA. 2003b, pp. 239-260.
5. Duncan, R. N-(2-Hydroxypropyl)methacrylamide copolymer conjugates. In Polymeric Drug Delivery Systems, By Kwon, G.S. Ed.; Marcel Dekker: New York, 2005a, pp. 1-92.
6. Ponzani, V.; Bressolle, F.; Haug, I.J.; Galtier, M.; Blayac, J.P. Cancer Chemother. Pharmacol., 1994, 35, 1.
7. Schechter, B.; Neumann, A.; Wilchek, M.; Arnon, R. J. Control. Release, 1989, 10, 75.
8. Takahashi, K.; Seki, T.; Nishimura, K.; Minamude, S.; Iwabuchi, M.; Ono, M.; Nagamine, S.; Horinishi, H. Jpn. J. Cancer Res., 1985, 76, 68.
9. Avgaustakis, K.; Beletsi, A.; Panagi, Z.; Klepetsanis, P.; Karydas, A.G.; Ithakissios, D.S. J. Control. Release, 2002, 79, 123.
10. Newman, M.S.; Colbern, G.T.; Working, P.K.; Engbers, C.; Amantea, M.A. Cancer Chemother. Pharmacol., 1999, 43, 1.
11. Jing-Shi, Z.; Imai, T.; Otagiri, M. Arch. Toxicol., 2000, 74, 300.
12. Imai, T.; Fujii, K.; Shiraishi, S.; Otagiri, M. J. Pharm. Sci., 1997, 86, 244.
13. Nishiyama, N.S.; Okazaki, H.; Cabral, H.; Miyamoto, M.; Kato, Y.; Sugiyama, Y.; Nishio, K.; Matsumura, Y.; Kataoka, K. Cancer Res., 2003, 63, 8977.
14. Nakashima, M.; Ichinose, K.; Kanematsu, T.; Masunaga, T.; Ohya, Y.; Ouchi, T.; Tomiyama, N.; Sasaki, H.; Ichikawa, M. Biol. Pharm. Bull., 1999, 22, 756.
15. Sezaki, H.; Takakura, Y.; Hashida, M. Adv. Drug Deliv. Rev., 1989, 3, 247.
16. Mayer, L.D.; Masin, D.; Nayar, R.; Boman, N.L.; Bally, M.B. Br. J. Cancer, 1995, 71, 482.
17. Lim, H.J.; Masin, D.; Madden, T.D.; Bally, M.B. J. Pharmacol. Exp. Ther., 1997, 281, 566.
18. Subramanian, D.; Muller, M.T. Oncol. Res., 1995, 7, 461.
19. Gabizon, A.; Goren, D.; Fuks, Z.; Meshorer, A.; Barenholz, Y. Br. J. Cancer, 1985, 51, 681.
20. Kaufman, S.H. Biochim. Biophys. Acta, 1998, 1400, 195.
21. Brunsveld, L.; Folmer, B.J.B.; Meijer, E.W.; Sijbesma, R.P. Chem. Rev., 2001, 101, 4071.
22. Sinha, V.R.; Kumria, R. Int. J. Pharm., 2001, 224, 19-38.
23. Garnier, C.; Axelos, M.A.V.; Thibault, J.F. Carbohydr. Res., 1993, 240, 219.
24. Verma, A.K.; Sachin, K.; Saxena, A.; Bohidar, H.B. Curr. Pharm. Biotech., 2005, 6, 121.
25. Bohidar, H.B. In Handbook of Polyelectrolytes-II, American Scientific Publishers: USA., 2002, 117.
26. Hörer, O.L.; Nicolau, C. FEBS Letts., 1971, 14, 262.
27. Golla, E.D.; Ayres, G.H. Talanta, 1973, 20, 199.
28. Loehrer, P.J.; Einhorn, L.H. Ann. Int. Med., 1984, 100, 704.
29. Davis, S.S. Trends Biotechnol., 1997, 15, 217.
30. Moghimi, M.S.; Hunter, A.C.; Murray, J.C. Pharmacol. Rev., 2001, 53, 283.
31. Farris, F.F.; King, F.G.; Dedrick, R.L.; Litterst, C.L. J. Pharmacokinet. Biopharm., 1985, 13, 13.
32. Duncan, R. Targeting and intracellular delivery of drugs. In Encyclopedia of Molecular Cell Biology and Molecular Medicine, in press. Ed. Meyers, R.A. Weinheim, Germany: Wiley-VCH Verlag, 2005b.