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Shang Y., Li X., Cui H., He P., Thilmony R., Chintamanani S., Zwiesler-Vollick J., Gopalan S., Tang X., and Zhou J.M. RAR1, a central player in plant immunity, is targeted by Pseudomonas syringae effector AvrB. Proc Natl Acad Sci U S A 103 (2006) 19200-19205
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(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 19200-19205
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Shang, Y.1
Li, X.2
Cui, H.3
He, P.4
Thilmony, R.5
Chintamanani, S.6
Zwiesler-Vollick, J.7
Gopalan, S.8
Tang, X.9
Zhou, J.M.10
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43
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A type III effector ADP-ribosylates RNA-binding proteins and quells plant immunity
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The authors demonstrated that HopU1 is a functional ADP-ribosyl transferase that targets several RNA-binding proteins in plants. One of these targets, GRP7, is a novel component of the PTI pathway and is required for disease resistance.
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Fu Z.Q., Guo M., Jeong B.R., Tian F., Elthon T.E., Cerny R.L., Staiger D., and Alfano J.R. A type III effector ADP-ribosylates RNA-binding proteins and quells plant immunity. Nature 447 (2007) 284-288. The authors demonstrated that HopU1 is a functional ADP-ribosyl transferase that targets several RNA-binding proteins in plants. One of these targets, GRP7, is a novel component of the PTI pathway and is required for disease resistance.
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(2007)
Nature
, vol.447
, pp. 284-288
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Fu, Z.Q.1
Guo, M.2
Jeong, B.R.3
Tian, F.4
Elthon, T.E.5
Cerny, R.L.6
Staiger, D.7
Alfano, J.R.8
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44
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34447542796
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A bacterial E3 ubiquitin ligase targets a host protein kinase to disrupt plant immunity
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The authors showed that the tomato protein kinase Fen recognizes the N terminus of the P. syringae effector AvrPtoB to trigger ETI. The C terminus of AvrPtoB directly targets Fen for ubiquitin-dependent degradation, and thereby reverses the outcome of interaction.
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Rosebrock T.R., Zeng L., Brady J.J., Abramovitch R.B., Xiao F., and Martin G.B. A bacterial E3 ubiquitin ligase targets a host protein kinase to disrupt plant immunity. Nature 448 (2007) 370-374. The authors showed that the tomato protein kinase Fen recognizes the N terminus of the P. syringae effector AvrPtoB to trigger ETI. The C terminus of AvrPtoB directly targets Fen for ubiquitin-dependent degradation, and thereby reverses the outcome of interaction.
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(2007)
Nature
, vol.448
, pp. 370-374
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Rosebrock, T.R.1
Zeng, L.2
Brady, J.J.3
Abramovitch, R.B.4
Xiao, F.5
Martin, G.B.6
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45
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30844458212
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A bacterial inhibitor of host programmed cell death defenses is an E3 ubiquitin ligase
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Janjusevic R., Abramovitch R.B., Martin G.B., and Stebbins C.E. A bacterial inhibitor of host programmed cell death defenses is an E3 ubiquitin ligase. Science 311 (2006) 222-226
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(2006)
Science
, vol.311
, pp. 222-226
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Janjusevic, R.1
Abramovitch, R.B.2
Martin, G.B.3
Stebbins, C.E.4
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46
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33644527550
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Type III effector AvrPtoB requires intrinsic E3 ubiquitin ligase activity to suppress plant cell death and immunity
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Abramovitch R.B., Janjusevic R., Stebbins C.E., and Martin G.B. Type III effector AvrPtoB requires intrinsic E3 ubiquitin ligase activity to suppress plant cell death and immunity. Proc Natl Acad Sci U S A 103 (2006) 2851-2856
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(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 2851-2856
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Abramovitch, R.B.1
Janjusevic, R.2
Stebbins, C.E.3
Martin, G.B.4
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47
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3042748124
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A family of conserved bacterial effectors inhibits salicylic acid-mediated basal immunity and promotes disease necrosis in plants
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DebRoy S., Thilmony R., Kwack Y.B., Nomura K., and He S.Y. A family of conserved bacterial effectors inhibits salicylic acid-mediated basal immunity and promotes disease necrosis in plants. Proc Natl Acad Sci U S A 101 (2004) 9927-9932
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(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9927-9932
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DebRoy, S.1
Thilmony, R.2
Kwack, Y.B.3
Nomura, K.4
He, S.Y.5
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48
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33746002275
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A bacterial virulence protein suppresses host innate immunity to cause plant disease
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The authors identified the first host target protein involved in virulence function of a plant bacterial effector. The study also uncovered AtMIN7 as a novel regulatory component in plant defenses.
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Nomura K., Debroy S., Lee Y.H., Pumplin N., Jones J., and He S.Y. A bacterial virulence protein suppresses host innate immunity to cause plant disease. Science 313 (2006) 220-223. The authors identified the first host target protein involved in virulence function of a plant bacterial effector. The study also uncovered AtMIN7 as a novel regulatory component in plant defenses.
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(2006)
Science
, vol.313
, pp. 220-223
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Nomura, K.1
Debroy, S.2
Lee, Y.H.3
Pumplin, N.4
Jones, J.5
He, S.Y.6
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49
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33745894351
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Os8N3 is a host disease-susceptibility gene for bacterial blight of rice
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The paper showed that the X. oryzae pv. oryzae effector PthXo1 activates the transcription of a rice gene, Os8N3, for virulence, providing evidence that the AvrBs3/PthA family effectors function by inducing susceptibility genes in plants.
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Yang B., Sugio A., and White F.F. Os8N3 is a host disease-susceptibility gene for bacterial blight of rice. Proc Natl Acad Sci U S A 103 (2006) 10503-10508. The paper showed that the X. oryzae pv. oryzae effector PthXo1 activates the transcription of a rice gene, Os8N3, for virulence, providing evidence that the AvrBs3/PthA family effectors function by inducing susceptibility genes in plants.
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(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 10503-10508
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Yang, B.1
Sugio, A.2
White, F.F.3
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50
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34547511837
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Two type III effector genes of Xanthomonas oryzae pv. oryzae control the induction of the host genes OsTFIIAgamma1 and OsTFX1 during bacterial blight of rice
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Sugio A., Yang B., Zhu T., and White F.F. Two type III effector genes of Xanthomonas oryzae pv. oryzae control the induction of the host genes OsTFIIAgamma1 and OsTFX1 during bacterial blight of rice. Proc Natl Acad Sci U S A 104 (2007) 10720-10725
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(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 10720-10725
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Sugio, A.1
Yang, B.2
Zhu, T.3
White, F.F.4
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51
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35548942766
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A bacterial effector acts as a plant transcription factor and induces a cell size regulator
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The report showed for the first time a bacterial effector protein directly targets a eukaryotic promoter element to turn on the host gene.
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Kay S., Hahn S., Marois E., Hause G., and Bonas U. A bacterial effector acts as a plant transcription factor and induces a cell size regulator. Science 318 (2007) 648-651. The report showed for the first time a bacterial effector protein directly targets a eukaryotic promoter element to turn on the host gene.
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(2007)
Science
, vol.318
, pp. 648-651
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Kay, S.1
Hahn, S.2
Marois, E.3
Hause, G.4
Bonas, U.5
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52
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35548939950
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Plant pathogen recognition mediated by promoter activation of the pepper Bs3 resistance gene
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The authors showed that plant resistance gene Bs3 uses a promoter element to detect the bacterial effector AvrBs3 and trigger ETI, providing evidence that a plant resistance gene may have evolved as a decoy for the intended target of the effector.
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Römer P., Hahn S., Jordan T., Strauss T., Bonas U., and Lahaye T. Plant pathogen recognition mediated by promoter activation of the pepper Bs3 resistance gene. Science 318 (2007) 645-648. The authors showed that plant resistance gene Bs3 uses a promoter element to detect the bacterial effector AvrBs3 and trigger ETI, providing evidence that a plant resistance gene may have evolved as a decoy for the intended target of the effector.
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(2007)
Science
, vol.318
, pp. 645-648
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Römer, P.1
Hahn, S.2
Jordan, T.3
Strauss, T.4
Bonas, U.5
Lahaye, T.6
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