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MAMPs and MIMPs: proposed classifications for inducers of innate immunity
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Mackey D., and McFall A.J. MAMPs and MIMPs: proposed classifications for inducers of innate immunity. Mol Microbiol 61 (2006) 1365-1371
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Mol Microbiol
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Mackey, D.1
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The plant immune system
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A concise review that summarizes recent understanding of the plant immune response upon PAMP and effector stimulation. The authors point out evolutionary dynamics in plant immunity.
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Jones J.D., and Dangl J.L. The plant immune system. Nature 444 (2006) 323-329. A concise review that summarizes recent understanding of the plant immune response upon PAMP and effector stimulation. The authors point out evolutionary dynamics in plant immunity.
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Nature
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Jones, J.D.1
Dangl, J.L.2
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Plants and animals: a different taste for microbes?
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An elaborate review that describes and compares PAMPs recognized by plants and animals. The authors highlight similarities and differences in the PAMP perception systems and provide evidence for convergent evolution.
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Zipfel C., and Felix G. Plants and animals: a different taste for microbes?. Curr Opin Plant Biol 8 (2005) 353-360. An elaborate review that describes and compares PAMPs recognized by plants and animals. The authors highlight similarities and differences in the PAMP perception systems and provide evidence for convergent evolution.
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Curr Opin Plant Biol
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Zipfel, C.1
Felix, G.2
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Plants have a sensitive perception system for the most conserved domain of bacterial flagellin
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Felix G., Duran J.D., Volko S., and Boller T. Plants have a sensitive perception system for the most conserved domain of bacterial flagellin. Plant J 18 (1999) 265-276
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Felix, G.1
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Innate Immunity in Arabidopsis thaliana: lipopolysaccharides activate nitric oxide synthase (NOS) and induce defense genes
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Zeidler D., Zahringer U., Gerber I., Dubery I., Hartung T., Bors W., Hutzler P., and Durner J. Innate Immunity in Arabidopsis thaliana: lipopolysaccharides activate nitric oxide synthase (NOS) and induce defense genes. Proc Natl Acad Sci U S A 101 (2004) 15811-15816
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Proc Natl Acad Sci U S A
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Zeidler, D.1
Zahringer, U.2
Gerber, I.3
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Bors, W.6
Hutzler, P.7
Durner, J.8
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33846588296
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The lipopolysaccharide of Sinorhizobium meliloti suppresses defense-associated gene expression in cell cultures of the host plant Medicago truncatula
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Tellstrom V., Usadel B., Thimm O., Stitt M., Kuster H., and Niehaus K. The lipopolysaccharide of Sinorhizobium meliloti suppresses defense-associated gene expression in cell cultures of the host plant Medicago truncatula. Plant Physiol 143 (2007) 825-837
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Usadel, B.2
Thimm, O.3
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The N terminus of bacterial elongation factor Tu elicits innate immunity in Arabidopsis plants
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Kunze G., Zipfel C., Robatzek S., Niehaus K., Boller T., and Felix G. The N terminus of bacterial elongation factor Tu elicits innate immunity in Arabidopsis plants. Plant Cell 16 (2004) 3496-3507
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Plant Cell
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Kunze, G.1
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Molecular sensing of bacteria in plants. The highly conserved RNA-binding motif RNP-1 of bacterial cold shock proteins is recognized as an elicitor signal in tobacco
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Felix G., and Boller T. Molecular sensing of bacteria in plants. The highly conserved RNA-binding motif RNP-1 of bacterial cold shock proteins is recognized as an elicitor signal in tobacco. J Biol Chem 278 (2003) 6201-6208
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Host-pathogen interactions: IX. Quantitative assays of elicitor activity and characterization of the elicitor present in the extracellular medium of cultures of Phytophthora megasperma var. sojae
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Ayers A.R., Ebel J., Finelli F., Berger N., and Albersheim P. Host-pathogen interactions: IX. Quantitative assays of elicitor activity and characterization of the elicitor present in the extracellular medium of cultures of Phytophthora megasperma var. sojae. Plant Physiol 57 (1976) 751-759
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Pep-13, a plant defense-inducing pathogen-associated pattern from Phytophthora transglutaminases
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Brunner F., Rosahl S., Lee J., Rudd J.J., Geiler C., Kauppinen S., Rasmussen G., Scheel D., and Nurnberger T. Pep-13, a plant defense-inducing pathogen-associated pattern from Phytophthora transglutaminases. EMBO J 21 (2002) 6681-6688
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Brunner, F.1
Rosahl, S.2
Lee, J.3
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Geiler, C.5
Kauppinen, S.6
Rasmussen, G.7
Scheel, D.8
Nurnberger, T.9
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11
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0034129286
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Differences in the recognition of glucan elicitor signals between rice and soybean: beta-glucan fragments from the rice blast disease fungus Pyricularia oryzae that elicit phytoalexin biosynthesis in suspension-cultured rice cells
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Yamaguchi T., Yamada A., Hong N., Ogawa T., Ishii T., and Shibuya N. Differences in the recognition of glucan elicitor signals between rice and soybean: beta-glucan fragments from the rice blast disease fungus Pyricularia oryzae that elicit phytoalexin biosynthesis in suspension-cultured rice cells. Plant Cell 12 (2000) 817-826
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Plant Cell
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Yamaguchi, T.1
Yamada, A.2
Hong, N.3
Ogawa, T.4
Ishii, T.5
Shibuya, N.6
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12
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0033746803
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Linear beta-1,3 glucans are elicitors of defense responses in tobacco
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Klarzynski O., Plesse B., Joubert J.M., Yvin J.C., Kopp M., Kloareg B., and Fritig B. Linear beta-1,3 glucans are elicitors of defense responses in tobacco. Plant Physiol 124 (2000) 1027-1038
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Klarzynski, O.1
Plesse, B.2
Joubert, J.M.3
Yvin, J.C.4
Kopp, M.5
Kloareg, B.6
Fritig, B.7
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13
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0033799396
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Identification of high-affinity-binding sites for the hepta-beta-glucoside elicitor in membranes of the model legumes Medicago truncatula and Lotus japonicus
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Cote F., Roberts K.A., and Hahn M.G. Identification of high-affinity-binding sites for the hepta-beta-glucoside elicitor in membranes of the model legumes Medicago truncatula and Lotus japonicus. Planta 211 (2000) 596-605
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Cote, F.1
Roberts, K.A.2
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0028885210
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Molecular characterization of nucleotide sequences encoding the extracellular glycoprotein elicitor from Phytophthora megasperma
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Sacks W., Nurnberger T., Hahlbrock K., and Scheel D. Molecular characterization of nucleotide sequences encoding the extracellular glycoprotein elicitor from Phytophthora megasperma. Mol Gen Genet 246 (1995) 45-55
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Sacks, W.1
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Ethylene biosynthesis-inducing protein from cellulysin is an endoxylanase
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Fuchs Y., Saxena A., Gamble H.R., and Anderson J.D. Ethylene biosynthesis-inducing protein from cellulysin is an endoxylanase. Plant Physiol 89 (1989) 138-143
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Fuchs, Y.1
Saxena, A.2
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Anderson, J.D.4
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Identification of an essential component of the elicitation active site of the EIX protein elicitor
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Rotblat B., Enshell-Seijffers D., Gershoni J.M., Schuster S., and Avni A. Identification of an essential component of the elicitation active site of the EIX protein elicitor. Plant J 32 (2002) 1049-1055
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Rotblat, B.1
Enshell-Seijffers, D.2
Gershoni, J.M.3
Schuster, S.4
Avni, A.5
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17
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33845512033
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Unique characteristics of Xanthomonas oryzae pv. oryzae AvrXa21 and implications for plant innate immunity
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The authors propose that AvrXa21 is a molecule playing a role in bacterial quorum sensing and cannot be attributed to classical PAMP or effector definition.
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Lee S.W., Han S.W., Bartley L.E., and Ronald P.C. Unique characteristics of Xanthomonas oryzae pv. oryzae AvrXa21 and implications for plant innate immunity. Proc Natl Acad Sci U S A 103 (2006) 18395-18400. The authors propose that AvrXa21 is a molecule playing a role in bacterial quorum sensing and cannot be attributed to classical PAMP or effector definition.
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Proc Natl Acad Sci U S A
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Lee, S.W.1
Han, S.W.2
Bartley, L.E.3
Ronald, P.C.4
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18
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0034644685
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Flagellin from an incompatible strain of Pseudomonas avenae induces a resistance response in cultured rice cells
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Che F.S., Nakajima Y., Tanaka N., Iwano M., Yoshida T., Takayama S., Kadota I., and Isogai A. Flagellin from an incompatible strain of Pseudomonas avenae induces a resistance response in cultured rice cells. J Biol Chem 275 (2000) 32347-32356
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J Biol Chem
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Che, F.S.1
Nakajima, Y.2
Tanaka, N.3
Iwano, M.4
Yoshida, T.5
Takayama, S.6
Kadota, I.7
Isogai, A.8
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19
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0037361893
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Post-translational modification of flagellin determines the specificity of HR induction
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Taguchi F., Shimizu R., Inagaki Y., Toyoda K., Shiraishi T., and Ichinose Y. Post-translational modification of flagellin determines the specificity of HR induction. Plant Cell Physiol 44 (2003) 342-349
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(2003)
Plant Cell Physiol
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Taguchi, F.1
Shimizu, R.2
Inagaki, Y.3
Toyoda, K.4
Shiraishi, T.5
Ichinose, Y.6
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20
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33846896457
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Early events in the pathogenicity of Pseudomonas syringae on Nicotiana benthamiana
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This paper demonstrates that flagellin monomers from Pst DC3000 elicit a HR response in N. benthamiana, which requires expression of NbFLS2.
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Hann D.R., and Rathjen J.P. Early events in the pathogenicity of Pseudomonas syringae on Nicotiana benthamiana. Plant J 49 (2007) 607-618. This paper demonstrates that flagellin monomers from Pst DC3000 elicit a HR response in N. benthamiana, which requires expression of NbFLS2.
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(2007)
Plant J
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Hann, D.R.1
Rathjen, J.P.2
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21
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0035845575
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Receptor-like kinases from Arabidopsis form a monophyletic gene family related to animal receptor kinases
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Shiu S.H., and Bleecker A.B. Receptor-like kinases from Arabidopsis form a monophyletic gene family related to animal receptor kinases. Proc Natl Acad Sci U S A 98 (2001) 10763-10768
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(2001)
Proc Natl Acad Sci U S A
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Shiu, S.H.1
Bleecker, A.B.2
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22
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26944457732
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Phylogenomic analysis of the receptor-like proteins of rice and Arabidopsis
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Fritz-Laylin L.K., Krishnamurthy N., Tor M., Sjolander K.V., and Jones J.D. Phylogenomic analysis of the receptor-like proteins of rice and Arabidopsis. Plant Physiol 138 (2005) 611-623
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(2005)
Plant Physiol
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Fritz-Laylin, L.K.1
Krishnamurthy, N.2
Tor, M.3
Sjolander, K.V.4
Jones, J.D.5
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23
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1942520270
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Bacterial disease resistance in Arabidopsis through flagellin perception
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This report demonstrates that flg22 perception contributes to plant immunity against pathogenic bacteria. FLS2 appears to play a role in pre-invasive immunity, and flg22 was shown to trigger post-invasive resistance.
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Zipfel C., Robatzek S., Navarro L., Oakeley E.J., Jones J.D., Felix G., and Boller T. Bacterial disease resistance in Arabidopsis through flagellin perception. Nature 428 (2004) 764-767. This report demonstrates that flg22 perception contributes to plant immunity against pathogenic bacteria. FLS2 appears to play a role in pre-invasive immunity, and flg22 was shown to trigger post-invasive resistance.
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(2004)
Nature
, vol.428
, pp. 764-767
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Zipfel, C.1
Robatzek, S.2
Navarro, L.3
Oakeley, E.J.4
Jones, J.D.5
Felix, G.6
Boller, T.7
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24
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33646525169
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Perception of the bacterial MAMP EF-Tu by the receptor EFR restricts Agrobacterium-mediated transformation
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This elegant study led to the identification of the EF-Tu receptor EFR in Arabidopsis. The authors observed that flg22 and elf18 induce the binding site of each PAMP. On the basis of a candidate approach focusing on flg22 and elf18 upregulated LRR-RLKs and screening a respective knockout collection they were able to identify an elf18 insensitive mutant. Expression of this RLK rendered normally elf18 insensitive N. benthamiana responsive, proving that EFR encodes the EF-Tu receptor.
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Zipfel C., Kunze G., Chinchilla D., Caniard A., Jones J.D., Boller T., and Felix G. Perception of the bacterial MAMP EF-Tu by the receptor EFR restricts Agrobacterium-mediated transformation. Cell 125 (2006) 749-760. This elegant study led to the identification of the EF-Tu receptor EFR in Arabidopsis. The authors observed that flg22 and elf18 induce the binding site of each PAMP. On the basis of a candidate approach focusing on flg22 and elf18 upregulated LRR-RLKs and screening a respective knockout collection they were able to identify an elf18 insensitive mutant. Expression of this RLK rendered normally elf18 insensitive N. benthamiana responsive, proving that EFR encodes the EF-Tu receptor.
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(2006)
Cell
, vol.125
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Zipfel, C.1
Kunze, G.2
Chinchilla, D.3
Caniard, A.4
Jones, J.D.5
Boller, T.6
Felix, G.7
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25
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0033634664
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FLS2: an LRR receptor-like kinase involved in the perception of the bacterial elicitor flagellin in Arabidopsis
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Gomez-Gomez L., and Boller T. FLS2: an LRR receptor-like kinase involved in the perception of the bacterial elicitor flagellin in Arabidopsis. Mol Cell 5 (2000) 1003-1011
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(2000)
Mol Cell
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Gomez-Gomez, L.1
Boller, T.2
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26
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33644780918
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Ligand-induced endocytosis of the pattern recognition receptor FLS2 in Arabidopsis
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This paper shows that FLS2 is internalized upon activation by its ligand flg22. Presented date also support the idea that FLS2 endocytosis plays a role in flg22 signaling.
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Robatzek S., Chinchilla D., and Boller T. Ligand-induced endocytosis of the pattern recognition receptor FLS2 in Arabidopsis. Genes Dev 20 (2006) 537-542. This paper shows that FLS2 is internalized upon activation by its ligand flg22. Presented date also support the idea that FLS2 endocytosis plays a role in flg22 signaling.
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(2006)
Genes Dev
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, pp. 537-542
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Robatzek, S.1
Chinchilla, D.2
Boller, T.3
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27
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33644749576
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The Arabidopsis receptor kinase FLS2 binds flg22 and determines the specificity of flagellin perception
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FLS2 was proposed to be the flg22 receptor on the basis of genetic evidence. Here, the authors have done biochemical and physiological experiments that show FLS2 is the flg22 receptor. Immunoprecipitation of FLS2 and radioactive labeled flg22 demonstrates a physical interaction of both. Expression of FLS2 in tomato transfers flagellin responsiveness characteristic of Arabidopsis.
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Chinchilla D., Bauer Z., Regenass M., Boller T., and Felix G. The Arabidopsis receptor kinase FLS2 binds flg22 and determines the specificity of flagellin perception. Plant Cell 18 (2006) 465-476. FLS2 was proposed to be the flg22 receptor on the basis of genetic evidence. Here, the authors have done biochemical and physiological experiments that show FLS2 is the flg22 receptor. Immunoprecipitation of FLS2 and radioactive labeled flg22 demonstrates a physical interaction of both. Expression of FLS2 in tomato transfers flagellin responsiveness characteristic of Arabidopsis.
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(2006)
Plant Cell
, vol.18
, pp. 465-476
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Chinchilla, D.1
Bauer, Z.2
Regenass, M.3
Boller, T.4
Felix, G.5
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28
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33644872221
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The autophosphorylated Ser686, Thr688, and Ser689 residues in the intracellular juxtamembrane domain of XA21 are implicated in stability control of rice receptor-like kinase
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Xu W.H., Wang Y.S., Liu G.Z., Chen X., Tinjuangjun P., Pi L.Y., and Song W.Y. The autophosphorylated Ser686, Thr688, and Ser689 residues in the intracellular juxtamembrane domain of XA21 are implicated in stability control of rice receptor-like kinase. Plant J 45 (2006) 740-751
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Plant J
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Xu, W.H.1
Wang, Y.S.2
Liu, G.Z.3
Chen, X.4
Tinjuangjun, P.5
Pi, L.Y.6
Song, W.Y.7
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29
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33947504480
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Rice XA21-binding protein 3 is a ubiquitin ligase required for full Xa21-mediated disease resistance
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Wang Y.S., Pi L.Y., Chen X., Chakrabarty P.K., Jiang J., De Leon A.L., Liu G.Z., Li L., Benny U., Oard J., Ronald P.C., and Song W.Y. Rice XA21-binding protein 3 is a ubiquitin ligase required for full Xa21-mediated disease resistance. Plant Cell 18 (2006) 3635-3646
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Plant Cell
, vol.18
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Wang, Y.S.1
Pi, L.Y.2
Chen, X.3
Chakrabarty, P.K.4
Jiang, J.5
De Leon, A.L.6
Liu, G.Z.7
Li, L.8
Benny, U.9
Oard, J.10
Ronald, P.C.11
Song, W.Y.12
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30
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33746582708
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Plant cells recognize chitin fragments for defense signaling through a plasma membrane receptor
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This paper describes the biochemical purification and identification of the chitin-binding site in rice. The corresponding gene, CEBiP, was found to encode a LysM-containing RLP. Silencing of CEBiP reduced responsiveness to chitin fragments, which suggest that CEBiP is involved in chitin recognition and signaling.
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Kaku H., Nishizawa Y., Ishii-Minami N., Akimoto-Tomiyama C., Dohmae N., Takio K., Minami E., and Shibuya N. Plant cells recognize chitin fragments for defense signaling through a plasma membrane receptor. Proc Natl Acad Sci U S A 103 (2006) 11086-11091. This paper describes the biochemical purification and identification of the chitin-binding site in rice. The corresponding gene, CEBiP, was found to encode a LysM-containing RLP. Silencing of CEBiP reduced responsiveness to chitin fragments, which suggest that CEBiP is involved in chitin recognition and signaling.
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Proc Natl Acad Sci U S A
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Kaku, H.1
Nishizawa, Y.2
Ishii-Minami, N.3
Akimoto-Tomiyama, C.4
Dohmae, N.5
Takio, K.6
Minami, E.7
Shibuya, N.8
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31
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2942683505
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The receptor for the fungal elicitor ethylene-inducing xylanase is a member of a resistance-like gene family in tomato
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Genetic mapping in tomato led to the identification of the receptor for xylanase, EIX. Two homologous LRR-type RLPs, LeEix1 and 2, were shown to mediate EIX-binding, whereas only LeEix2 triggered HR upon EIX stimulation. Mutation of the endocytic motif abolished LeEix2 function.
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Ron M., and Avni A. The receptor for the fungal elicitor ethylene-inducing xylanase is a member of a resistance-like gene family in tomato. Plant Cell 16 (2004) 1604-1615. Genetic mapping in tomato led to the identification of the receptor for xylanase, EIX. Two homologous LRR-type RLPs, LeEix1 and 2, were shown to mediate EIX-binding, whereas only LeEix2 triggered HR upon EIX stimulation. Mutation of the endocytic motif abolished LeEix2 function.
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Plant Cell
, vol.16
, pp. 1604-1615
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Ron, M.1
Avni, A.2
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32
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0346463047
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An ancient enzyme domain hidden in the putative beta-glucan elicitor receptor of soybean may play an active part in the perception of pathogen-associated molecular patterns during broad host resistance
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Fliegmann J., Mithofer A., Wanner G., and Ebel J. An ancient enzyme domain hidden in the putative beta-glucan elicitor receptor of soybean may play an active part in the perception of pathogen-associated molecular patterns during broad host resistance. J Biol Chem 279 (2004) 1132-1140
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J Biol Chem
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Fliegmann, J.1
Mithofer, A.2
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Ebel, J.4
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33
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Catalytic properties of the bifunctional soybean beta-glucan-binding protein, a member of family 81 glycoside hydrolases
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Fliegmann J., Montel E., Djulic A., Cottaz S., Driguez H., and Ebel J. Catalytic properties of the bifunctional soybean beta-glucan-binding protein, a member of family 81 glycoside hydrolases. FEBS Lett 579 (2005) 6647-6652
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FEBS Lett
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Fliegmann, J.1
Montel, E.2
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Ebel, J.6
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34
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27944454718
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Pre- and postinvasion defenses both contribute to non-host resistance in Arabidopsis
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Lipka V., Dittgen J., Bednarek P., Bhat R., Wiermer M., Stein M., Landtag J., Brandt W., Rosahl S., Scheel D., Llorente F., Molina A., Parker J., Somerville S., and Schulze-Lefert P. Pre- and postinvasion defenses both contribute to non-host resistance in Arabidopsis. Science 310 (2005) 1180-1183
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Science
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Lipka, V.1
Dittgen, J.2
Bednarek, P.3
Bhat, R.4
Wiermer, M.5
Stein, M.6
Landtag, J.7
Brandt, W.8
Rosahl, S.9
Scheel, D.10
Llorente, F.11
Molina, A.12
Parker, J.13
Somerville, S.14
Schulze-Lefert, P.15
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35
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Ralstonia solanacearum needs motility for invasive virulence on tomato
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Tans-Kersten J., Huang H., and Allen C. Ralstonia solanacearum needs motility for invasive virulence on tomato. J Bacteriol 183 (2001) 3597-3605
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J Bacteriol
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Tans-Kersten, J.1
Huang, H.2
Allen, C.3
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36
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33748129962
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Plant stomata function in innate immunity against bacterial invasion
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This paper demonstrates that bacteria move towards plant stomata, which are actively closed upon bacterial sensing. Stomata closure can be triggered by LPS and flg22, and requires FLS2 function. This shows that PAMP perception mediates pre-invasive immunity. Phytopathogenic bacteria are able to re-open closed stomata by producing the compound coronatine, a structural homologue of plant jasmonic acid. PAMP-triggered stomata closure was dependent on NO, SA and the guard cell specific kinase OST1.
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