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Volumn 29, Issue 5, 2008, Pages 868-872

Increased circulating urotensin II in cirrhosis: Potential implications in liver disease

Author keywords

Cirrhosis; Liver disease; Portal hypertension; Urotensin II

Indexed keywords

ACT 058362; OCTREOTIDE; PALOSURAN; RECEPTOR; RECEPTOR BLOCKING AGENT; SOMATOSTATIN; UNCLASSIFIED DRUG; UROTENSIN II; UROTENSIN II RECEPTOR;

EID: 42049108791     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2007.08.020     Document Type: Article
Times cited : (12)

References (49)
  • 1
    • 0037025061 scopus 로고    scopus 로고
    • Involvement of the nitric oxide/L-arginine and sympathetic nervous systems on the vasodepressor action of human urotensin II in anesthetized rats
    • Abdelrahman A.M., and Pang C.C. Involvement of the nitric oxide/L-arginine and sympathetic nervous systems on the vasodepressor action of human urotensin II in anesthetized rats. Life Sci 71 7 (2002) 819-825
    • (2002) Life Sci , vol.71 , Issue.7 , pp. 819-825
    • Abdelrahman, A.M.1    Pang, C.C.2
  • 2
    • 0033575930 scopus 로고    scopus 로고
    • Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14
    • Ames R.S., Sarau H.M., Chambers J.K., Willette R.N., Aiyar N.V., Romanic A.M., et al. Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14. Nature 401 6750 (1999) 282-286
    • (1999) Nature , vol.401 , Issue.6750 , pp. 282-286
    • Ames, R.S.1    Sarau, H.M.2    Chambers, J.K.3    Willette, R.N.4    Aiyar, N.V.5    Romanic, A.M.6
  • 3
    • 0033839169 scopus 로고    scopus 로고
    • Human urotensin-II is an endothelium-dependent vasodilator in rat small arteries
    • Bottrill F.E., Douglas S.A., Hiley C.R., and White R. Human urotensin-II is an endothelium-dependent vasodilator in rat small arteries. Br J Pharmacol 130 8 (2000) 1865-1870
    • (2000) Br J Pharmacol , vol.130 , Issue.8 , pp. 1865-1870
    • Bottrill, F.E.1    Douglas, S.A.2    Hiley, C.R.3    White, R.4
  • 4
    • 0027178984 scopus 로고
    • Impaired responsiveness to angiotensin II in experimental cirrhosis: role of nitric oxide
    • Castro A., Jimenez W., Claria J., Ros J., Martinez J.M., Bosch M., et al. Impaired responsiveness to angiotensin II in experimental cirrhosis: role of nitric oxide. Hepatology 18 2 (1993) 367-372
    • (1993) Hepatology , vol.18 , Issue.2 , pp. 367-372
    • Castro, A.1    Jimenez, W.2    Claria, J.3    Ros, J.4    Martinez, J.M.5    Bosch, M.6
  • 5
    • 27744438834 scopus 로고    scopus 로고
    • Urotensin II: evidence for cardiac, hepatic and renal production
    • Charles C.J., Rademaker M.T., Richards A.M., and Yandle T.G. Urotensin II: evidence for cardiac, hepatic and renal production. Peptides 26 11 (2005) 2211-2214
    • (2005) Peptides , vol.26 , Issue.11 , pp. 2211-2214
    • Charles, C.J.1    Rademaker, M.T.2    Richards, A.M.3    Yandle, T.G.4
  • 6
    • 3042713965 scopus 로고    scopus 로고
    • Plasma concentration of urotensin II is raised in hypertension
    • Cheung B.M., Leung R., Man Y.B., and Wong L.Y. Plasma concentration of urotensin II is raised in hypertension. J Hypertens 22 7 (2004) 1341-1344
    • (2004) J Hypertens , vol.22 , Issue.7 , pp. 1341-1344
    • Cheung, B.M.1    Leung, R.2    Man, Y.B.3    Wong, L.Y.4
  • 7
    • 0030174350 scopus 로고    scopus 로고
    • Distribution and molecular forms of urotensin II and its role in cardiovascular regulation in vertebrates
    • Conlon J.M., Yano K., Waugh D., and Hazon N. Distribution and molecular forms of urotensin II and its role in cardiovascular regulation in vertebrates. J Exp Zool 275 2-3 (1996) 226-238
    • (1996) J Exp Zool , vol.275 , Issue.2-3 , pp. 226-238
    • Conlon, J.M.1    Yano, K.2    Waugh, D.3    Hazon, N.4
  • 8
    • 0032428160 scopus 로고    scopus 로고
    • Cloning of the cDNA encoding the urotensin II precursor in frog and human reveals intense expression of the urotensin II gene in motoneurons of the spinal cord
    • Coulouarn Y., Lihrmann I., Jegou S., Anouar Y., Tostivint H., Beauvillain J.C., et al. Cloning of the cDNA encoding the urotensin II precursor in frog and human reveals intense expression of the urotensin II gene in motoneurons of the spinal cord. Proc Natl Acad Sci USA 95 26 (1998) 15803-15808
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.26 , pp. 15803-15808
    • Coulouarn, Y.1    Lihrmann, I.2    Jegou, S.3    Anouar, Y.4    Tostivint, H.5    Beauvillain, J.C.6
  • 9
    • 0842266248 scopus 로고    scopus 로고
    • From 'gills to pills': urotensin-II as a regulator of mammalian cardiorenal function
    • Douglas S.A., Dhanak D., and Johns D.G. From 'gills to pills': urotensin-II as a regulator of mammalian cardiorenal function. Trends Pharmacol Sci 25 2 (2004) 76-85
    • (2004) Trends Pharmacol Sci , vol.25 , Issue.2 , pp. 76-85
    • Douglas, S.A.1    Dhanak, D.2    Johns, D.G.3
  • 10
    • 0033638718 scopus 로고    scopus 로고
    • Differential vasoconstrictor activity of human urotensin-II in vascular tissue isolated from the rat, mouse, dog, pig, marmoset and cynomolgus monkey
    • Douglas S.A., Sulpizio A.C., Piercy V., Sarau H.M., Ames R.S., Aiyar N.V., et al. Differential vasoconstrictor activity of human urotensin-II in vascular tissue isolated from the rat, mouse, dog, pig, marmoset and cynomolgus monkey. Br J Pharmacol 131 7 (2000) 1262-1274
    • (2000) Br J Pharmacol , vol.131 , Issue.7 , pp. 1262-1274
    • Douglas, S.A.1    Sulpizio, A.C.2    Piercy, V.3    Sarau, H.M.4    Ames, R.S.5    Aiyar, N.V.6
  • 11
    • 0037042532 scopus 로고    scopus 로고
    • Congestive heart failure and expression of myocardial urotensin II
    • Douglas S.A., Tayara L., Ohlstein E.H., Halawa N., and Giaid A. Congestive heart failure and expression of myocardial urotensin II. Lancet 359 9322 (2002) 1990-1997
    • (2002) Lancet , vol.359 , Issue.9322 , pp. 1990-1997
    • Douglas, S.A.1    Tayara, L.2    Ohlstein, E.H.3    Halawa, N.4    Giaid, A.5
  • 12
    • 0037207058 scopus 로고    scopus 로고
    • Plasma levels and cardiovascular gene expression of urotensin-II in human heart failure
    • Dschietzig T., Bartsch C., Pregla R., Zurbrugg H.R., Armbruster F.P., Richter C., et al. Plasma levels and cardiovascular gene expression of urotensin-II in human heart failure. Regul Pept 110 1 (2002) 33-38
    • (2002) Regul Pept , vol.110 , Issue.1 , pp. 33-38
    • Dschietzig, T.1    Bartsch, C.2    Pregla, R.3    Zurbrugg, H.R.4    Armbruster, F.P.5    Richter, C.6
  • 13
    • 0036261206 scopus 로고    scopus 로고
    • Molecular and pharmacological characterization of genes encoding urotensin-II peptides and their cognate G-protein-coupled receptors from the mouse and monkey
    • Elshourbagy N.A., Douglas S.A., Shabon U., Harrison S., Duddy G., Sechler J.L., et al. Molecular and pharmacological characterization of genes encoding urotensin-II peptides and their cognate G-protein-coupled receptors from the mouse and monkey. Br J Pharmacol 136 1 (2002) 9-22
    • (2002) Br J Pharmacol , vol.136 , Issue.1 , pp. 9-22
    • Elshourbagy, N.A.1    Douglas, S.A.2    Shabon, U.3    Harrison, S.4    Duddy, G.5    Sechler, J.L.6
  • 14
    • 0029165886 scopus 로고
    • The role of vasoactive mediators in portal hypertension
    • Garcia-Pagan J.C., Bosch J., and Rodes J. The role of vasoactive mediators in portal hypertension. Semin Gastrointest Dis 6 3 (1995) 140-147
    • (1995) Semin Gastrointest Dis , vol.6 , Issue.3 , pp. 140-147
    • Garcia-Pagan, J.C.1    Bosch, J.2    Rodes, J.3
  • 15
    • 7044285778 scopus 로고    scopus 로고
    • Bolus injection of human UII in conscious rats evokes a biphasic haemodynamic response
    • Gardiner S.M., March J.E., Kemp P.A., and Bennett T. Bolus injection of human UII in conscious rats evokes a biphasic haemodynamic response. Br J Pharmacol 143 3 (2004) 422-430
    • (2004) Br J Pharmacol , vol.143 , Issue.3 , pp. 422-430
    • Gardiner, S.M.1    March, J.E.2    Kemp, P.A.3    Bennett, T.4
  • 16
    • 0035030726 scopus 로고    scopus 로고
    • Depressor and regionally-selective vasodilator effects of human and rat urotensin II in conscious rats
    • Gardiner S.M., March J.E., Kemp P.A., Davenport A.P., and Bennett T. Depressor and regionally-selective vasodilator effects of human and rat urotensin II in conscious rats. Br J Pharmacol 132 8 (2001) 1625-1629
    • (2001) Br J Pharmacol , vol.132 , Issue.8 , pp. 1625-1629
    • Gardiner, S.M.1    March, J.E.2    Kemp, P.A.3    Davenport, A.P.4    Bennett, T.5
  • 17
    • 33645106688 scopus 로고    scopus 로고
    • Regional heterogeneity in the haemodynamic responses to urotensin II infusion in relation to UT receptor localisation
    • Gardiner S.M., March J.E., Kemp P.A., Maguire J.J., Kuc R.E., Davenport A.P., et al. Regional heterogeneity in the haemodynamic responses to urotensin II infusion in relation to UT receptor localisation. Br J Pharmacol 147 6 (2006) 612-621
    • (2006) Br J Pharmacol , vol.147 , Issue.6 , pp. 612-621
    • Gardiner, S.M.1    March, J.E.2    Kemp, P.A.3    Maguire, J.J.4    Kuc, R.E.5    Davenport, A.P.6
  • 18
    • 33746276776 scopus 로고    scopus 로고
    • Circulating urotensin II levels in moderate to severe congestive heart failure: its relations with myocardial function and well established neurohormonal markers
    • Gruson D., Rousseau M.F., Ahn S.A., van Linden F., and Ketelslegers J.M. Circulating urotensin II levels in moderate to severe congestive heart failure: its relations with myocardial function and well established neurohormonal markers. Peptides 27 6 (2006) 1527-1531
    • (2006) Peptides , vol.27 , Issue.6 , pp. 1527-1531
    • Gruson, D.1    Rousseau, M.F.2    Ahn, S.A.3    van Linden, F.4    Ketelslegers, J.M.5
  • 19
    • 2642578590 scopus 로고    scopus 로고
    • Octreotide antagonizes the urotensin II (UII) induced aortic contractions in normal and cirrhotic rats
    • Heller J., Schepke N.F., Neef M., and Sauerbruch T. Octreotide antagonizes the urotensin II (UII) induced aortic contractions in normal and cirrhotic rats. J Hepatol 38 Suppl 2 (2003) 59
    • (2003) J Hepatol , vol.38 , Issue.SUPPL. 2 , pp. 59
    • Heller, J.1    Schepke, N.F.2    Neef, M.3    Sauerbruch, T.4
  • 20
    • 0036892492 scopus 로고    scopus 로고
    • Increased urotensin II plasma levels in patients with cirrhosis and portal hypertension
    • Heller J., Schepke M., Neef M., Woitas R., Rabe C., and Sauerbruch T. Increased urotensin II plasma levels in patients with cirrhosis and portal hypertension. J Hepatol 37 6 (2002) 767-772
    • (2002) J Hepatol , vol.37 , Issue.6 , pp. 767-772
    • Heller, J.1    Schepke, M.2    Neef, M.3    Woitas, R.4    Rabe, C.5    Sauerbruch, T.6
  • 21
    • 33644870801 scopus 로고    scopus 로고
    • Defective RhoA/Rho-kinase signaling contributes to vascular hypocontractility and vasodilation in cirrhotic rats
    • Hennenberg M., Biecker E., Trebicka J., Jochem K., Zhou Q., Schmidt M., et al. Defective RhoA/Rho-kinase signaling contributes to vascular hypocontractility and vasodilation in cirrhotic rats. Gastroenterology 130 3 (2006) 838-854
    • (2006) Gastroenterology , vol.130 , Issue.3 , pp. 838-854
    • Hennenberg, M.1    Biecker, E.2    Trebicka, J.3    Jochem, K.4    Zhou, Q.5    Schmidt, M.6
  • 22
    • 0036954108 scopus 로고    scopus 로고
    • Pathophysiology of portal hypertension
    • Kapoor D., and Sarin S.K. Pathophysiology of portal hypertension. J Gastroenterol Hepatol 17 Suppl (2002) S482-S487
    • (2002) J Gastroenterol Hepatol , vol.17 , Issue.SUPPL
    • Kapoor, D.1    Sarin, S.K.2
  • 23
    • 42049094153 scopus 로고    scopus 로고
    • Serum urotensin II elevation in chronic liver disease-relationship to severity of cirrhosis and portal hypertension
    • Kemp W., Krum H., Colman J., Bailey M., and Richards S.R. Serum urotensin II elevation in chronic liver disease-relationship to severity of cirrhosis and portal hypertension. J Gastro Hepatol 20 Suppl 1 (2005) A86
    • (2005) J Gastro Hepatol , vol.20 , Issue.SUPPL. 1
    • Kemp, W.1    Krum, H.2    Colman, J.3    Bailey, M.4    Richards, S.R.5
  • 24
    • 42049093946 scopus 로고    scopus 로고
    • Urotensin II is a relevant vasoactive mediator of cirrhotic portal hypertension in humans
    • Kemp W., Krum H., Colman J., Yandle T., Richards M., and Roberts S. Urotensin II is a relevant vasoactive mediator of cirrhotic portal hypertension in humans. Hepatology 44 S1 (2006) 202A
    • (2006) Hepatology , vol.44 , Issue.SUPPL.1
    • Kemp, W.1    Krum, H.2    Colman, J.3    Yandle, T.4    Richards, M.5    Roberts, S.6
  • 25
    • 18044392247 scopus 로고    scopus 로고
    • Urotensin II: a vascular mediator in health and disease
    • Kemp W., Roberts S.K., and Krum H. Urotensin II: a vascular mediator in health and disease. Curr Vascular Pharmacol 3 2 (2005) 159-168
    • (2005) Curr Vascular Pharmacol , vol.3 , Issue.2 , pp. 159-168
    • Kemp, W.1    Roberts, S.K.2    Krum, H.3
  • 26
    • 35148890582 scopus 로고    scopus 로고
    • Intrahepatic urotensin II expression is down-regulated in liver cirrhosis
    • Leifeld L., Clemens C., Spengler U., Sauerbruch T., and Heller J. Intrahepatic urotensin II expression is down-regulated in liver cirrhosis. J Hepatology 42 Suppl. 2 (2005) 69
    • (2005) J Hepatology , vol.42 , Issue.SUPPL. 2 , pp. 69
    • Leifeld, L.1    Clemens, C.2    Spengler, U.3    Sauerbruch, T.4    Heller, J.5
  • 27
    • 0033539884 scopus 로고    scopus 로고
    • Identification of urotensin II as the endogenous ligand for the orphan G-protein-coupled receptor GPR14
    • Liu Q., Pong S.S., Zeng Z., Zhang Q., Howard A.D., Williams Jr. D.L., et al. Identification of urotensin II as the endogenous ligand for the orphan G-protein-coupled receptor GPR14. Biochem Biophys Res Commun 266 1 (1999) 174-178
    • (1999) Biochem Biophys Res Commun , vol.266 , Issue.1 , pp. 174-178
    • Liu, Q.1    Pong, S.S.2    Zeng, Z.3    Zhang, Q.4    Howard, A.D.5    Williams Jr., D.L.6
  • 28
    • 0035208378 scopus 로고    scopus 로고
    • Co-expression of urotensin II and its receptor (GPR14) in human cardiovascular and renal tissues
    • Matsushita M., Shichiri M., Imai T., Iwashina M., Tanaka H., Takasu N., et al. Co-expression of urotensin II and its receptor (GPR14) in human cardiovascular and renal tissues. J Hypertens 19 12 (2001) 2185-2190
    • (2001) J Hypertens , vol.19 , Issue.12 , pp. 2185-2190
    • Matsushita, M.1    Shichiri, M.2    Imai, T.3    Iwashina, M.4    Tanaka, H.5    Takasu, N.6
  • 29
    • 17944366961 scopus 로고    scopus 로고
    • Vasoactive substances in the circulatory dysfunction of cirrhosis
    • Moller S., Bendtsen F., and Henriksen J.H. Vasoactive substances in the circulatory dysfunction of cirrhosis. Scand J Clin Lab Invest 61 6 (2001) 421-429
    • (2001) Scand J Clin Lab Invest , vol.61 , Issue.6 , pp. 421-429
    • Moller, S.1    Bendtsen, F.2    Henriksen, J.H.3
  • 30
    • 0034055378 scopus 로고    scopus 로고
    • Urotensin II: better than somatostatin for portal hypertension?
    • Newby D.E., and Jalan R. Urotensin II: better than somatostatin for portal hypertension?. Hepatology 31 5 (2000) 1201-1202
    • (2000) Hepatology , vol.31 , Issue.5 , pp. 1201-1202
    • Newby, D.E.1    Jalan, R.2
  • 31
  • 32
    • 0033202995 scopus 로고    scopus 로고
    • Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulation of vasoconstriction
    • Nothacker H.P., Wang Z., McNeill A.M., Saito Y., Merten S., O'Dowd B., et al. Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulation of vasoconstriction. Nat Cell Biol 1 6 (1999) 383-385
    • (1999) Nat Cell Biol , vol.1 , Issue.6 , pp. 383-385
    • Nothacker, H.P.1    Wang, Z.2    McNeill, A.M.3    Saito, Y.4    Merten, S.5    O'Dowd, B.6
  • 33
    • 0025210027 scopus 로고
    • Decreased systemic vascular sensitivity to norepinephrine in portal hypertensive rats: role of hyperglucagonism
    • Pizcueta M.P., Casamitjana R., Bosch J., and Rodes J. Decreased systemic vascular sensitivity to norepinephrine in portal hypertensive rats: role of hyperglucagonism. Am J Physiol 258 2 Pt 1 (1990) G191-G195
    • (1990) Am J Physiol , vol.258 , Issue.2 PART 1
    • Pizcueta, M.P.1    Casamitjana, R.2    Bosch, J.3    Rodes, J.4
  • 37
    • 0035827716 scopus 로고    scopus 로고
    • Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinase
    • Sauzeau V., Le Mellionnec E., Bertoglio J., Scalbert E., Pacaud P., and Loirand G. Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinase. Circ Res 88 11 (2001) 1102-1104
    • (2001) Circ Res , vol.88 , Issue.11 , pp. 1102-1104
    • Sauzeau, V.1    Le Mellionnec, E.2    Bertoglio, J.3    Scalbert, E.4    Pacaud, P.5    Loirand, G.6
  • 38
    • 0034849461 scopus 로고    scopus 로고
    • Cellular and molecular basis of portal hypertension
    • Shah V. Cellular and molecular basis of portal hypertension. Clin Liver Dis 5 3 (2001) 629-644
    • (2001) Clin Liver Dis , vol.5 , Issue.3 , pp. 629-644
    • Shah, V.1
  • 41
    • 5144231012 scopus 로고    scopus 로고
    • Elevated plasma levels of immunoreactive urotensin II and its increased urinary excretion in patients with Type 2 diabetes mellitus: association with progress of diabetic nephropathy
    • Totsune K., Takahashi K., Arihara Z., Sone M., Murakami O., Ito S., et al. Elevated plasma levels of immunoreactive urotensin II and its increased urinary excretion in patients with Type 2 diabetes mellitus: association with progress of diabetic nephropathy. Peptides 25 10 (2004) 1809-1814
    • (2004) Peptides , vol.25 , Issue.10 , pp. 1809-1814
    • Totsune, K.1    Takahashi, K.2    Arihara, Z.3    Sone, M.4    Murakami, O.5    Ito, S.6
  • 43
    • 34547292414 scopus 로고    scopus 로고
    • Urotensin II receptor antagonist Palosuran lowers portal pressure and improves renal perfusion in cirrhotic rats
    • Trebicka J., Hennenberg M., Eckhardt A., Biecker E., Sauerbruch T., and Heller J. Urotensin II receptor antagonist Palosuran lowers portal pressure and improves renal perfusion in cirrhotic rats. Hepatology 44 S1 (2006) 202A
    • (2006) Hepatology , vol.44 , Issue.SUPPL.1
    • Trebicka, J.1    Hennenberg, M.2    Eckhardt, A.3    Biecker, E.4    Sauerbruch, T.5    Heller, J.6
  • 44
    • 33746319906 scopus 로고    scopus 로고
    • Human urotensin II as a link between hypertension and coronary artery disease
    • Watanabe T., Kanome T., Miyazaki A., and Katagiri T. Human urotensin II as a link between hypertension and coronary artery disease. Hypertens Res 29 6 (2006) 375-387
    • (2006) Hypertens Res , vol.29 , Issue.6 , pp. 375-387
    • Watanabe, T.1    Kanome, T.2    Miyazaki, A.3    Katagiri, T.4
  • 45
    • 0033427391 scopus 로고    scopus 로고
    • Nitric oxide and portal hypertension: its role in the regulation of intrahepatic and splanchnic vascular resistance
    • Wiest R., and Groszmann R.J. Nitric oxide and portal hypertension: its role in the regulation of intrahepatic and splanchnic vascular resistance. Semin Liver Dis 19 4 (1999) 411-426
    • (1999) Semin Liver Dis , vol.19 , Issue.4 , pp. 411-426
    • Wiest, R.1    Groszmann, R.J.2
  • 46
    • 0032938259 scopus 로고    scopus 로고
    • NO overproduction by eNOS precedes hyperdynamic splanchnic circulation in portal hypertensive rats
    • Wiest R., Shah V., Sessa W.C., and Groszmann R.J. NO overproduction by eNOS precedes hyperdynamic splanchnic circulation in portal hypertensive rats. Am J Physiol 276 4 Pt 1 (1999) G1043-G1051
    • (1999) Am J Physiol , vol.276 , Issue.4 PART 1
    • Wiest, R.1    Shah, V.2    Sessa, W.C.3    Groszmann, R.J.4
  • 47
    • 0141590352 scopus 로고    scopus 로고
    • Urotensin II is a nitric oxide-dependent vasodilator and natriuretic peptide in the rat kidney
    • Zhang A.Y., Chen Y.F., Zhang D.X., Yi F.X., Qi J., Andrade-Gordon P., et al. Urotensin II is a nitric oxide-dependent vasodilator and natriuretic peptide in the rat kidney. Am J Physiol Renal Physiol 285 4 (2003) F792-F798
    • (2003) Am J Physiol Renal Physiol , vol.285 , Issue.4
    • Zhang, A.Y.1    Chen, Y.F.2    Zhang, D.X.3    Yi, F.X.4    Qi, J.5    Andrade-Gordon, P.6
  • 48
    • 33747810129 scopus 로고    scopus 로고
    • Intrahepatic upregulation of RhoA and Rho-kinase signaling contributes to increased hepatic vascular resistance in rats with secondary biliary cirrhosis
    • Zhou Q., Hennenberg M., Trebicka J., Jochem K., Leifeld L., Biecker E., et al. Intrahepatic upregulation of RhoA and Rho-kinase signaling contributes to increased hepatic vascular resistance in rats with secondary biliary cirrhosis. Gut 55 9 (2006) 1296-1305
    • (2006) Gut , vol.55 , Issue.9 , pp. 1296-1305
    • Zhou, Q.1    Hennenberg, M.2    Trebicka, J.3    Jochem, K.4    Leifeld, L.5    Biecker, E.6
  • 49
    • 33749371071 scopus 로고    scopus 로고
    • The role of urotensin II in cardiovascular and renal physiology and diseases
    • Zhu Y.C., Zhu Y.Z., and Moore P.K. The role of urotensin II in cardiovascular and renal physiology and diseases. Br J Pharmacol 148 7 (2006) 884-901
    • (2006) Br J Pharmacol , vol.148 , Issue.7 , pp. 884-901
    • Zhu, Y.C.1    Zhu, Y.Z.2    Moore, P.K.3


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