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Volumn 68, Issue 7, 2008, Pages 2427-2435

Antitumor effects of Mucin 1/sec involves the modulation of urokinase-type plasminogen activator and signal transducer and activator of transcription 1 expression in tumor cells

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MUCIN 1; PROTEIN SERINE KINASE; STAT1 PROTEIN; STAT3 PROTEIN; UROKINASE;

EID: 42049107075     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-5651     Document Type: Article
Times cited : (14)

References (39)
  • 1
    • 0024798333 scopus 로고
    • Oligosaccharide differences in the DF3 sialomucin antigen from normal human milk and the BT 20 human breast carcinoma cell line
    • Hull SR, Bright A, Carraway KL, et al. Oligosaccharide differences in the DF3 sialomucin antigen from normal human milk and the BT 20 human breast carcinoma cell line. Cancer Commun 1989;1:261-7.
    • (1989) Cancer Commun , vol.1 , pp. 261-267
    • Hull, S.R.1    Bright, A.2    Carraway, K.L.3
  • 2
    • 0030466993 scopus 로고    scopus 로고
    • Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells
    • Lloyd KO, Burchell J, Kudryashov V, Yin BW, Taylor-Papadimitriou J. Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells. J Biol Chem 1996;271:33325-34.
    • (1996) J Biol Chem , vol.271 , pp. 33325-33334
    • Lloyd, K.O.1    Burchell, J.2    Kudryashov, V.3    Yin, B.W.4    Taylor-Papadimitriou, J.5
  • 4
    • 33745142522 scopus 로고    scopus 로고
    • MUC1 splice variants in human ocular surface tissues: Possible differences between dry eye patients and normal controls
    • Imbert Y, Darling DS, Jumblatt MM, et al. MUC1 splice variants in human ocular surface tissues: possible differences between dry eye patients and normal controls. Exp Eye Res 2006;83:493-501.
    • (2006) Exp Eye Res , vol.83 , pp. 493-501
    • Imbert, Y.1    Darling, D.S.2    Jumblatt, M.M.3
  • 5
    • 4344652717 scopus 로고    scopus 로고
    • Transmembrane and truncated (SEC) isoforms of MUC1 in the human endometrium and fallopian tube
    • Hey NA, Meseguer M, Simon C, et al. Transmembrane and truncated (SEC) isoforms of MUC1 in the human endometrium and fallopian tube. Reprod Biol Endocrinol 2003;1:2.
    • (2003) Reprod Biol Endocrinol , vol.1 , pp. 2
    • Hey, N.A.1    Meseguer, M.2    Simon, C.3
  • 6
    • 0037054946 scopus 로고    scopus 로고
    • Expression of MUC1 splice variants in benign and malignant ovarian tumours
    • Obermair A, Schmid BC, Packer LM, et al. Expression of MUC1 splice variants in benign and malignant ovarian tumours. Int J Cancer 2002;100:166-71.
    • (2002) Int J Cancer , vol.100 , pp. 166-171
    • Obermair, A.1    Schmid, B.C.2    Packer, L.M.3
  • 7
    • 0025328854 scopus 로고
    • Human epithelial tumor antigen cDNA sequences. Differential splicing may generate multiple protein forms
    • Wreschner DH, Hareuveni M, Tsarfaty I, et al. Human epithelial tumor antigen cDNA sequences. Differential splicing may generate multiple protein forms. Eur J Biochem 1990;189:463-73.
    • (1990) Eur J Biochem , vol.189 , pp. 463-473
    • Wreschner, D.H.1    Hareuveni, M.2    Tsarfaty, I.3
  • 8
    • 3242786236 scopus 로고    scopus 로고
    • MUC1/sec-expressing tumors are rejected in vivo by a T cell-dependent mechanism and secrete high levels of CCL2
    • Grosso JF, Herbert LM, Owen JL, Lopez DM. MUC1/sec-expressing tumors are rejected in vivo by a T cell-dependent mechanism and secrete high levels of CCL2. J Immunol 2004;173:1721-30.
    • (2004) J Immunol , vol.173 , pp. 1721-1730
    • Grosso, J.F.1    Herbert, L.M.2    Owen, J.L.3    Lopez, D.M.4
  • 9
    • 7444271027 scopus 로고    scopus 로고
    • A unique mucin immunoenhancing peptide with antitumor properties
    • Herbert LM, Grosso JF, Dorsey M, Jr., et al. A unique mucin immunoenhancing peptide with antitumor properties. Cancer Res 2004;64:8077-84.
    • (2004) Cancer Res , vol.64 , pp. 8077-8084
    • Herbert, L.M.1    Grosso, J.F.2    Dorsey Jr., M.3
  • 11
    • 0036906177 scopus 로고    scopus 로고
    • uPAR: A versatile signalling orchestrator
    • Blasi F, Carmeliet P. uPAR: a versatile signalling orchestrator. Nat Rev Mol Cell Biol 2002;3:932-43.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 932-943
    • Blasi, F.1    Carmeliet, P.2
  • 12
    • 0037061736 scopus 로고    scopus 로고
    • Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells
    • Huang S, Bucana CD, Van Arsdall M, Fidler IJ. Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells. Oncogene 2002;21:2504-12.
    • (2002) Oncogene , vol.21 , pp. 2504-2512
    • Huang, S.1    Bucana, C.D.2    Van Arsdall, M.3    Fidler, I.J.4
  • 13
    • 0036731485 scopus 로고    scopus 로고
    • Stats: Transcriptional control and biological impact
    • Levy DE, Darnell JE, Jr. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 2002;3:651-62.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 651-662
    • Levy, D.E.1    Darnell Jr, J.E.2
  • 14
    • 0036793979 scopus 로고    scopus 로고
    • Prognostic significance of signal transducer and activator of transcription 1 activation in breast cancer
    • Widschwendter A, Tonko-Geymayer S, Welte T, et al. Prognostic significance of signal transducer and activator of transcription 1 activation in breast cancer. Clin Cancer Res 2002;8:3065-74.
    • (2002) Clin Cancer Res , vol.8 , pp. 3065-3074
    • Widschwendter, A.1    Tonko-Geymayer, S.2    Welte, T.3
  • 15
    • 0025191261 scopus 로고
    • Expansion of immunoregulatory macrophages by granulocyte-macrophage colony-stimulating factor derived from a murine mammary tumor
    • Fu YX, Watson G, Jimenez JJ, Wang Y, Lopez DM. Expansion of immunoregulatory macrophages by granulocyte-macrophage colony-stimulating factor derived from a murine mammary tumor. Cancer Res 1990;50:227-34.
    • (1990) Cancer Res , vol.50 , pp. 227-234
    • Fu, Y.X.1    Watson, G.2    Jimenez, J.J.3    Wang, Y.4    Lopez, D.M.5
  • 16
    • 0020654082 scopus 로고
    • Vascularization and tumour volume estimations of solitary liver tumours in rats
    • Carlsson G, Ekelund L, Stigsson L, Hafstrom L. Vascularization and tumour volume estimations of solitary liver tumours in rats. Ann Chir Gynaecol 1983;72:187-91.
    • (1983) Ann Chir Gynaecol , vol.72 , pp. 187-191
    • Carlsson, G.1    Ekelund, L.2    Stigsson, L.3    Hafstrom, L.4
  • 17
    • 0018854046 scopus 로고
    • Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates
    • Heussen C, Dowdle EB. Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates. Anal Biochem 1980;102:196-202.
    • (1980) Anal Biochem , vol.102 , pp. 196-202
    • Heussen, C.1    Dowdle, E.B.2
  • 18
    • 33845865825 scopus 로고    scopus 로고
    • Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment
    • Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev Immunol 2007;7:41-51.
    • (2007) Nat Rev Immunol , vol.7 , pp. 41-51
    • Yu, H.1    Kortylewski, M.2    Pardoll, D.3
  • 19
    • 3242699717 scopus 로고    scopus 로고
    • uPA and uPARin fibrinolysis, immunity and pathology
    • Mondino A, Blasi F. uPA and uPARin fibrinolysis, immunity and pathology. Trends Immunol 2004;25:450-5.
    • (2004) Trends Immunol , vol.25 , pp. 450-455
    • Mondino, A.1    Blasi, F.2
  • 20
    • 0034657904 scopus 로고    scopus 로고
    • Mechanisms of graft acceptance: Evidence that plasminogen activator controls donor-reactive delayed-type hypersensitivity responses in cardiac allograft acceptor mice
    • Bickerstaff AA, Xia D, Pelletier RP, Orosz CG. Mechanisms of graft acceptance: evidence that plasminogen activator controls donor-reactive delayed-type hypersensitivity responses in cardiac allograft acceptor mice. J Immunol 2000;164:5132-9.
    • (2000) J Immunol , vol.164 , pp. 5132-5139
    • Bickerstaff, A.A.1    Xia, D.2    Pelletier, R.P.3    Orosz, C.G.4
  • 21
    • 0025215307 scopus 로고
    • Mechanism of activation of latent recombinant transforming growth factor β 1 by plasmin
    • Lyons RM, Gentry LE, Purchio AF, Moses HL. Mechanism of activation of latent recombinant transforming growth factor β 1 by plasmin. J Cell Biol 1990;110:1361-7.
    • (1990) J Cell Biol , vol.110 , pp. 1361-1367
    • Lyons, R.M.1    Gentry, L.E.2    Purchio, A.F.3    Moses, H.L.4
  • 22
    • 0000778380 scopus 로고
    • Surface differentiation antigens of human mammary epithelial cells carried on the human milk fat globule
    • Ceriani RL, Thompson K, Peterson JA, Abraham S. Surface differentiation antigens of human mammary epithelial cells carried on the human milk fat globule. Proc Natl Acad Sci U S A 1977;74:582-6.
    • (1977) Proc Natl Acad Sci U S A , vol.74 , pp. 582-586
    • Ceriani, R.L.1    Thompson, K.2    Peterson, J.A.3    Abraham, S.4
  • 23
    • 9144251970 scopus 로고    scopus 로고
    • Gene expression profiling identifies clinically relevant subtypes of prostate cancer
    • Lapointe J, Li C, Higgins JP, et al. Gene expression profiling identifies clinically relevant subtypes of prostate cancer. Proc Natl Acad Sci U S A 2004;101:811-6.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 811-816
    • Lapointe, J.1    Li, C.2    Higgins, J.P.3
  • 24
    • 34548759771 scopus 로고    scopus 로고
    • Cutting edge: Transgenic expression of human MUC1 in IL-10-/-mice accelerates inflammatory bowel disease and progression to colon cancer
    • Beatty PL, Plevy SE, Sepulveda AR, Finn OJ. Cutting edge: transgenic expression of human MUC1 in IL-10-/-mice accelerates inflammatory bowel disease and progression to colon cancer. J Immunol 2007;179:735-9.
    • (2007) J Immunol , vol.179 , pp. 735-739
    • Beatty, P.L.1    Plevy, S.E.2    Sepulveda, A.R.3    Finn, O.J.4
  • 25
    • 9144231784 scopus 로고    scopus 로고
    • Increased expression of MUC1 in advanced pancreatic cancer
    • Hinoda Y, Ikematsu Y, Horinochi M, et al. Increased expression of MUC1 in advanced pancreatic cancer. J Gastroenterol 2003;38:1162-6.
    • (2003) J Gastroenterol , vol.38 , pp. 1162-1166
    • Hinoda, Y.1    Ikematsu, Y.2    Horinochi, M.3
  • 26
    • 34247624214 scopus 로고    scopus 로고
    • Oral premalignant lesions induce immune reactivity to both premalignant oral lesions and head and neck squamous cell carcinoma
    • Young MR, Neville BW, Chi AC, et al. Oral premalignant lesions induce immune reactivity to both premalignant oral lesions and head and neck squamous cell carcinoma. Cancer Immunol Immunother 2007;56:1077-86.
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 1077-1086
    • Young, M.R.1    Neville, B.W.2    Chi, A.C.3
  • 27
    • 0347123435 scopus 로고    scopus 로고
    • Mucins in cancer: Protection and control of the cell surface
    • Hollingsworth MA, Swanson BJ. Mucins in cancer: protection and control of the cell surface. Nat Rev Cancer 2004;4:45-60.
    • (2004) Nat Rev Cancer , vol.4 , pp. 45-60
    • Hollingsworth, M.A.1    Swanson, B.J.2
  • 28
    • 2942564135 scopus 로고    scopus 로고
    • Tumor-derived MUC1 mucins interact with differentiating monocytes and induce IL-10-12low regulatory dendritic cell
    • Monti P, Leone BE, Zerbi A, et al. Tumor-derived MUC1 mucins interact with differentiating monocytes and induce IL-10-12low regulatory dendritic cell. J Immunol 2004;172:7341-9.
    • (2004) J Immunol , vol.172 , pp. 7341-7349
    • Monti, P.1    Leone, B.E.2    Zerbi, A.3
  • 29
    • 20444403424 scopus 로고    scopus 로고
    • Recombinant tumor-associated MUC1 glycoprotein impairs the differentiation and function of dendritic cells
    • Rughetti A, Pellicciotta I, Biffoni M, et al. Recombinant tumor-associated MUC1 glycoprotein impairs the differentiation and function of dendritic cells. J Immunol 2005;174:7764-72.
    • (2005) J Immunol , vol.174 , pp. 7764-7772
    • Rughetti, A.1    Pellicciotta, I.2    Biffoni, M.3
  • 30
    • 0034650868 scopus 로고    scopus 로고
    • uPA/uPAR system is active in immature dendritic cells derived from CD14+CD34+ precursors and is down-regulated upon maturation
    • Ferrero E, Vettoretto K, Bondanza A, et al. uPA/uPAR system is active in immature dendritic cells derived from CD14+CD34+ precursors and is down-regulated upon maturation. J Immunol 2000;164:712-8.
    • (2000) J Immunol , vol.164 , pp. 712-718
    • Ferrero, E.1    Vettoretto, K.2    Bondanza, A.3
  • 31
    • 34848881592 scopus 로고    scopus 로고
    • NKT cell-derived urokinase-type plasminogen activator promotes peripheral tolerance associated with eye
    • Sonoda KH, Nakamura T, Young HA, et al. NKT cell-derived urokinase-type plasminogen activator promotes peripheral tolerance associated with eye. J Immunol 2007;179:2215-22.
    • (2007) J Immunol , vol.179 , pp. 2215-2222
    • Sonoda, K.H.1    Nakamura, T.2    Young, H.A.3
  • 32
    • 0029682495 scopus 로고    scopus 로고
    • Induction of primary cutaneous melanocytic neoplasms in urokinase-type plasminogen activator (uPA)-deficient and wild-type mice: Cellular blue nevi invade but do not progress to malignant melanoma in uPA-deficient animals
    • Shapiro RL, Duquette JG, Roses DF, et al. Induction of primary cutaneous melanocytic neoplasms in urokinase-type plasminogen activator (uPA)-deficient and wild-type mice: cellular blue nevi invade but do not progress to malignant melanoma in uPA-deficient animals. Cancer Res 1996;56:3597-604.
    • (1996) Cancer Res , vol.56 , pp. 3597-3604
    • Shapiro, R.L.1    Duquette, J.G.2    Roses, D.F.3
  • 34
    • 0032560475 scopus 로고    scopus 로고
    • Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice
    • Kaplan DH, Shankaran V, Dighe AS, et al. Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice. Proc Natl Acad Sci U S A 1998;95:7556-61.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7556-7561
    • Kaplan, D.H.1    Shankaran, V.2    Dighe, A.S.3
  • 35
    • 11144357779 scopus 로고    scopus 로고
    • Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells
    • Wang T, Niu G, Kortylewski M, et al. Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. Nat Med 2004;10:48-54.
    • (2004) Nat Med , vol.10 , pp. 48-54
    • Wang, T.1    Niu, G.2    Kortylewski, M.3
  • 38
    • 0036681991 scopus 로고    scopus 로고
    • Interferon-γ-dependent phagocytic cells are a critical component of innate immunity against metastatic mammary carcinoma
    • Pulaski BA, Smyth MJ, Ostrand-Rosenberg S. Interferon-γ-dependent phagocytic cells are a critical component of innate immunity against metastatic mammary carcinoma. Cancer Res 2002;62:4406-12.
    • (2002) Cancer Res , vol.62 , pp. 4406-4412
    • Pulaski, B.A.1    Smyth, M.J.2    Ostrand-Rosenberg, S.3
  • 39
    • 34548654133 scopus 로고    scopus 로고
    • Cross-talk between T cells and innate immune cells is crucial for IFN-γ-dependent tumor rejection
    • Li Z, Pradera F, Kammertoens T, et al. Cross-talk between T cells and innate immune cells is crucial for IFN-γ-dependent tumor rejection. J Immunol 2007;179:1568-76.
    • (2007) J Immunol , vol.179 , pp. 1568-1576
    • Li, Z.1    Pradera, F.2    Kammertoens, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.