Increased contractile response to 5-hydroxytryptamine1-receptor stimulation in pulmonary arteries from chronic hypoxic rats: Role of pharmacological synergy

British Journal of Pharmacology

Volumn 134, Issue 3, 2001, Pages 614-620

  Maclean, M R ^a   Morecroft, I ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Chronic hypoxia; Pharmacological synergy; Pulmonary artery; Pulmonary hypertension; Vascular tone; Vasoconstriction

Indexed keywords

4 AMINOPYRIDINE; 5 CARBAMOYLTRYPTAMINE; CALCIMYCIN; NEUROPEPTIDE Y; SEROTONIN 1 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; HYPOXIA; LONG TERM POTENTIATION; LUNG VASCULAR RESISTANCE; MEDIATOR RELEASE; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY HYPERTENSION; RAT; SMOOTH MUSCLE CONTRACTILITY; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

EID: 0034779893     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704273     Document Type: Article

References (29)

1. A study of nerves containing peptides in the pulmonary vasculature of healthy infants and children and of those with pulmonary hypertension
2. The effect of contractile agonists on isolated pulmonary arterial and venous muscle preparations derived from patients with primary pulmonary hypertension
3. The role of the reninangiotensin and neuropeptide systems in the pulmonary vasculature
4. Lipid mediator dysregulation in primary pulmonary hypertension
5. Characterisation of 5-HI receptors on human pulmonary artery and vein: Functional and binding studies
6. 1-like receptor mediating the amplifying action of 5-HT in the rabbit ear artery
7. Functional effects of 4-aminopyridine (4-AP) on pulmonary and systemic vessel from normoxic control and hypoxic pulmonary hypertensive rats
8. 1B receptor in small pulmonary arteries from rats with chronic hypoxic pulmonary hypertension
9. Resolution of pulmonary hypertension and other features induced by chronic hypoxia in rats during complete and intermittent normoxia
10. Inositol trisphosphate is revolved in norepinephrine- but not hypoxia-induced pulmonary arterial contraction
11. Neuropeptide Y receptors in pig spleen: Binding characteristics, reduction of cyclic AMP formation and calcium antagonist inhibition of vasoconstriction
12. Endothelin-1 and serotonin: Mediators of primary and secondary pulmonary hypertension
13. Pulmonary hypertension, anorexigens and 5-hydroxytryptamine: Pharmacological synergism in action?
14. 1-receptor-mediated vasoconstriction in bovine isolated pulmonary arteries: Influence of vascular endothelium
15. 1-like receptor mediated vasoconstriction in human pulmonary artery
16. 5-Hydroxytryptamine and the pulmonary circulation: Receptors, transporters and relevance to pulmonary arterial hypertension
17. Phosphodiesterase isoforms in the pulmonary arterial circulation of the rat: Changes in pulmonary hypertension
18. 2-adrenoceptor-mediated responses in the rabbit isolated pulmonary artery
19. 5-Hydroxytryptamine receptors mediating vasoconstriction in pulmonary arteries from control and pulmonary hypertensive rats
20. 2 receptor mediated contraction of the rabbit isolated femoral artery
21. 1B receptor
22. 1B-like receptors of the rabbit ear artery
23. Functions mediate by peripheral endothelin receptors
24. + currents to the resting potential and tone of rat pulmonary artery smooth muscle
25. Endothelin stimulates phospholipase C in cultured vascular smooth muscle cells
26. G protein-coupled-receptor cross-talk: The fine-tuning of multiple receptor-signalling pathways
27. A comparison of pathophysiological changes during hypobaric and normobaric hypoxia in rats
28. Activation of protein kinase C as a modulator of potentiated UK-14304-induced contractions in dog mesenteric artery and vein
29. Morphometry of the human pulmonary arterial tree