Aconitum sp. alkaloids: The modulation of voltage-dependent Na+ channels, toxicity and antinociceptive properties

European Journal of Pharmacology

Volumn 337, Issue 2-3, 1997, Pages 165-174

  Friese, Jutta ^a   Gleitz, Johannes ^a   Gutser, Ulrike T ^a   Heubach, Jürgen F ^a   Matthiesen, Theo ^b   Wilffert, Bob ^c   Selve, Norma ^b  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b GRÜNENTHAL GMBH   (Germany)

^c PRA International USA   (Netherlands)

Author keywords

Aconitum alkaloid; Antinociception; Na+ channel; Toxicity

Indexed keywords

ACONITINE; ALKALOID; ANALGESIC AGENT; MESACONITINE; SODIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; DRUG EFFECT; DRUG TOXICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ACONITINE; ALKALOIDS; ANIMALS; ARRHYTHMIA; CALCIUM; CEREBRAL CORTEX; DRUGS, CHINESE HERBAL; GUINEA PIGS; HEART ATRIA; HUMANS; ION CHANNEL GATING; LETHAL DOSE 50; MALE; MICE; PAIN MEASUREMENT; RATS; RATS, WISTAR; SODIUM; SODIUM CHANNELS; SYNAPTOSOMES;

EID: 0030697406     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01268-5     Document Type: Article

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