메뉴 건너뛰기




Volumn 22, Issue 4, 2008, Pages 927-934

Genotoxicity of thimerosal in cultured human lymphocytes with and without metabolic activation sister chromatid exchange analysis proliferation index and mitotic index

Author keywords

Genotoxicity; Mitotic index; Proliferation index; S9 activation system; Thimerosal

Indexed keywords

THIOMERSAL;

EID: 41949128170     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2008.01.012     Document Type: Article
Times cited : (23)

References (61)
  • 1
    • 0029014922 scopus 로고
    • Thimerosal is a frequent sensitizer but is not in the standard series
    • Aberer W., and Kränke B. Thimerosal is a frequent sensitizer but is not in the standard series. Contact Dermatitis 32 (1995) 367-368
    • (1995) Contact Dermatitis , vol.32 , pp. 367-368
    • Aberer, W.1    Kränke, B.2
  • 2
    • 0026073718 scopus 로고
    • Mouse micronucleus tests with known and suspect spindle poisons: results from two laboratories
    • Adler I.D., Kliesch U., Van Hummelen P., and Kirsch-Volders M. Mouse micronucleus tests with known and suspect spindle poisons: results from two laboratories. Mutagenesis 6 (1991) 47-53
    • (1991) Mutagenesis , vol.6 , pp. 47-53
    • Adler, I.D.1    Kliesch, U.2    Van Hummelen, P.3    Kirsch-Volders, M.4
  • 3
    • 0030828536 scopus 로고    scopus 로고
    • Allergic contact sensitizing chemicals as environmental carcinogens
    • Albert R.E. Allergic contact sensitizing chemicals as environmental carcinogens. Environmental Health Perspective 105 9 (1997) 940-948
    • (1997) Environmental Health Perspective , vol.105 , Issue.9 , pp. 940-948
    • Albert, R.E.1
  • 4
    • 0033897197 scopus 로고    scopus 로고
    • The tumorigenicity of mutagenic contact-sensitizing chemicals
    • Albert RE., and Magee PS. The tumorigenicity of mutagenic contact-sensitizing chemicals. Risk Analysis 20 (2000) 317-325
    • (2000) Risk Analysis , vol.20 , pp. 317-325
    • Albert, RE.1    Magee, PS.2
  • 5
    • 0023911366 scopus 로고
    • Chromosome aberrations, mitogen-induced blastogenesis and proliferative rate index in peripheral lymphocytes from 106 control individuals of U.K. population
    • Anderson D., Jenkinson P.C., Dewdeney R.S., Franis A.J., Godbert P., and Butterworth K.R. Chromosome aberrations, mitogen-induced blastogenesis and proliferative rate index in peripheral lymphocytes from 106 control individuals of U.K. population. Mutation Research 204 (1988) 407-420
    • (1988) Mutation Research , vol.204 , pp. 407-420
    • Anderson, D.1    Jenkinson, P.C.2    Dewdeney, R.S.3    Franis, A.J.4    Godbert, P.5    Butterworth, K.R.6
  • 6
    • 15244354740 scopus 로고    scopus 로고
    • In vitro genotoxic effects of the anticancer drug gemcitabine in human lymphocytes
    • Aydemir N., Serap C., and Bilaloǧlu R. In vitro genotoxic effects of the anticancer drug gemcitabine in human lymphocytes. Mutation Research 582 (2005) 35-41
    • (2005) Mutation Research , vol.582 , pp. 35-41
    • Aydemir, N.1    Serap, C.2    Bilaloǧlu, R.3
  • 7
    • 0031856258 scopus 로고    scopus 로고
    • The in vitro effect of bcarotene and mitomycin C on SCE frequency in Down's syndrome lymphocyte cultures
    • Bal F., Sahin F.I., Yirmibes M., Balci{dotless} A., and Menevse S. The in vitro effect of bcarotene and mitomycin C on SCE frequency in Down's syndrome lymphocyte cultures. Tohoku Journal Experimental Medicine 184 (1998) 295-300
    • (1998) Tohoku Journal Experimental Medicine , vol.184 , pp. 295-300
    • Bal, F.1    Sahin, F.I.2    Yirmibes, M.3    Balci, A.4    Menevse, S.5
  • 8
    • 0035025386 scopus 로고    scopus 로고
    • An assessment of thimerosal use in childhood vaccines
    • Ball LK., Ball R., and Pratt RD. An assessment of thimerosal use in childhood vaccines. Pediatrics 107 (2001) 1147-1154
    • (2001) Pediatrics , vol.107 , pp. 1147-1154
    • Ball, LK.1    Ball, R.2    Pratt, RD.3
  • 9
    • 0041589365 scopus 로고    scopus 로고
    • Thimerosal induces DNA breaks, Caspase-3 activation, membrane damage, and cell death in cultured human neurons and fibroblasts
    • Baskin D., Ngo H., and Didenko VD. Thimerosal induces DNA breaks, Caspase-3 activation, membrane damage, and cell death in cultured human neurons and fibroblasts. Toxicological Sciences 74 (2003) 361-368
    • (2003) Toxicological Sciences , vol.74 , pp. 361-368
    • Baskin, D.1    Ngo, H.2    Didenko, VD.3
  • 11
    • 14744272645 scopus 로고    scopus 로고
    • Thiomersal in vaccines: balancing the risk of adverse effects with the risk of vaccine-preventable disease
    • Bigham M., and Copes R. Thiomersal in vaccines: balancing the risk of adverse effects with the risk of vaccine-preventable disease. Drug Safe: International Journal Medical Toxicology. Drug Experience 28 (2005) 89-101
    • (2005) Drug Safe: International Journal Medical Toxicology. Drug Experience , vol.28 , pp. 89-101
    • Bigham, M.1    Copes, R.2
  • 12
    • 0032496143 scopus 로고    scopus 로고
    • Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss
    • Cai J., and Jones D.P. Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss. Journal Biological Chemistry 273 19 (1998) 11401-11404
    • (1998) Journal Biological Chemistry , vol.273 , Issue.19 , pp. 11401-11404
    • Cai, J.1    Jones, D.P.2
  • 13
    • 5044251143 scopus 로고    scopus 로고
    • Evaluation of sister chromatid exchange and chromosomal aberration frequencies in peripheral blood lymphocytes of gasoline station attendants
    • Çelik A., and Akbaş E. Evaluation of sister chromatid exchange and chromosomal aberration frequencies in peripheral blood lymphocytes of gasoline station attendants. Ecotoxicology and Environmental Safety 60 (2005) 106-112
    • (2005) Ecotoxicology and Environmental Safety , vol.60 , pp. 106-112
    • Çelik, A.1    Akbaş, E.2
  • 17
    • 30344458453 scopus 로고    scopus 로고
    • When science is not enough-a risk/benefit profile of thimerosal-containing vaccines
    • Clements C.J., and McIntyre P.B. When science is not enough-a risk/benefit profile of thimerosal-containing vaccines. Expert Opinion on Drug Safety 5 (2006) 17-29
    • (2006) Expert Opinion on Drug Safety , vol.5 , pp. 17-29
    • Clements, C.J.1    McIntyre, P.B.2
  • 19
    • 0033047488 scopus 로고    scopus 로고
    • Thimerosal: a versatile sulfhydryl reagent, calcium mobilizer, and cell function-modulating agent
    • Elferink J.G. Thimerosal: a versatile sulfhydryl reagent, calcium mobilizer, and cell function-modulating agent. General Pharmacology 33 1 (1999) 1-6
    • (1999) General Pharmacology , vol.33 , Issue.1 , pp. 1-6
    • Elferink, J.G.1
  • 22
    • 0027456242 scopus 로고
    • Thimerosal induced changes of intracellular calcium in human endothelial cells
    • Gericke M., Droogmans G., and Nilius B. Thimerosal induced changes of intracellular calcium in human endothelial cells. Cell Calcium 14 3 (1993) 201-207
    • (1993) Cell Calcium , vol.14 , Issue.3 , pp. 201-207
    • Gericke, M.1    Droogmans, G.2    Nilius, B.3
  • 23
    • 0037179201 scopus 로고    scopus 로고
    • Genotoxic evaluation of the furylethylene derivative 1-(5-bromofur-2-yl)-2-nitroethene in cultured human lymphocytes
    • González Borroto J.I., Creus A., and Marcos R. Genotoxic evaluation of the furylethylene derivative 1-(5-bromofur-2-yl)-2-nitroethene in cultured human lymphocytes. Mutation Research 519 (2002) 179-185
    • (2002) Mutation Research , vol.519 , pp. 179-185
    • González Borroto, J.I.1    Creus, A.2    Marcos, R.3
  • 24
    • 0032420762 scopus 로고    scopus 로고
    • Redox regulation of apoptotic cell death in the immune system
    • Hampton MB., and Orrenius S. Redox regulation of apoptotic cell death in the immune system. Toxicology Letters 102-103 (1998) 355-358
    • (1998) Toxicology Letters , vol.102-103 , pp. 355-358
    • Hampton, MB.1    Orrenius, S.2
  • 27
    • 0032478358 scopus 로고    scopus 로고
    • Alterations of thiol metabolism in human cell lines induced by low amounts of copper, mercury or cadmium ions
    • Hultberg B., Anderson A., and Isaksson A. Alterations of thiol metabolism in human cell lines induced by low amounts of copper, mercury or cadmium ions. Toxicology 126 (1998) 203-212
    • (1998) Toxicology , vol.126 , pp. 203-212
    • Hultberg, B.1    Anderson, A.2    Isaksson, A.3
  • 28
    • 0000437062 scopus 로고
    • Average generation time: a new method of analysis and quantitation of cellular proliferation kinetics
    • Ivett J.L., and Tice R.R. Average generation time: a new method of analysis and quantitation of cellular proliferation kinetics. Environmental Mutagenesis 4 (1982) 358
    • (1982) Environmental Mutagenesis , vol.4 , pp. 358
    • Ivett, J.L.1    Tice, R.R.2
  • 29
    • 7444224116 scopus 로고    scopus 로고
    • Thimerosal neurotoxicity is associated with glutathione depletion: protection with glutathione precursors
    • James S.J., Slikker W., Melnyk S., New E., Pogribna M., and Jernigan S. Thimerosal neurotoxicity is associated with glutathione depletion: protection with glutathione precursors. Neurotoxicology 26 (2005) 1-8
    • (2005) Neurotoxicology , vol.26 , pp. 1-8
    • James, S.J.1    Slikker, W.2    Melnyk, S.3    New, E.4    Pogribna, M.5    Jernigan, S.6
  • 30
    • 0037316481 scopus 로고    scopus 로고
    • Sevoflurane anaesthesia does not induce the formation of sister chromatid exchanges in peripheral blood lymphocytes of children
    • Krause T., Scholz J., Boettcher H., Wappler K.C., and Schutle am Esch J. Sevoflurane anaesthesia does not induce the formation of sister chromatid exchanges in peripheral blood lymphocytes of children. British Journal Anaesthesia 90 (2003) 233-235
    • (2003) British Journal Anaesthesia , vol.90 , pp. 233-235
    • Krause, T.1    Scholz, J.2    Boettcher, H.3    Wappler, K.C.4    Schutle am Esch, J.5
  • 31
    • 0033520969 scopus 로고    scopus 로고
    • Quality control by DNA repair
    • Lindahl T., and Wood R.D. Quality control by DNA repair. Science 286 (1999) 1897-1905
    • (1999) Science , vol.286 , pp. 1897-1905
    • Lindahl, T.1    Wood, R.D.2
  • 35
    • 0036689835 scopus 로고    scopus 로고
    • Biochemical and molecular basis of thimerosal-induced apoptosis in T-cells: major role of mitochondrial pathway
    • Makani S., Gollapudi S., Yel L., Chiplungar S., and Gupta S. Biochemical and molecular basis of thimerosal-induced apoptosis in T-cells: major role of mitochondrial pathway. Genes and Immunity 3 (2002) 270-278
    • (2002) Genes and Immunity , vol.3 , pp. 270-278
    • Makani, S.1    Gollapudi, S.2    Yel, L.3    Chiplungar, S.4    Gupta, S.5
  • 36
    • 0034011261 scopus 로고    scopus 로고
    • Oxyradicals and DNA damage
    • Marnett L.J. Oxyradicals and DNA damage. Carcinogenesis 21 (2000) 361-370
    • (2000) Carcinogenesis , vol.21 , pp. 361-370
    • Marnett, L.J.1
  • 37
    • 0037182153 scopus 로고    scopus 로고
    • Micronuclei and sister chromatid exchanges induced by capsaicin in human lymphocytes
    • Marques S., Oliveira N.G., Chaveca T., and Rueff J. Micronuclei and sister chromatid exchanges induced by capsaicin in human lymphocytes. Mutation Research 517 (2002) 39-46
    • (2002) Mutation Research , vol.517 , pp. 39-46
    • Marques, S.1    Oliveira, N.G.2    Chaveca, T.3    Rueff, J.4
  • 38
    • 0028171473 scopus 로고
    • Micronucleus test and metaphase analyses in mice exposed to known and suspected spindle poisons
    • Marrazzini A., Betti C., Bernacchi F., Barrai I., and Barale R. Micronucleus test and metaphase analyses in mice exposed to known and suspected spindle poisons. Mutagenesis 9 (1994) 505-515
    • (1994) Mutagenesis , vol.9 , pp. 505-515
    • Marrazzini, A.1    Betti, C.2    Bernacchi, F.3    Barrai, I.4    Barale, R.5
  • 39
    • 0001557779 scopus 로고
    • Toxicology and carcinogenesis of various chemicals used in the preparation of vaccines
    • Mason M.M., Cate C.C., and Baker J. Toxicology and carcinogenesis of various chemicals used in the preparation of vaccines. Clinical Toxicology 4 (1971) 185-204
    • (1971) Clinical Toxicology , vol.4 , pp. 185-204
    • Mason, M.M.1    Cate, C.C.2    Baker, J.3
  • 41
    • 0030565418 scopus 로고    scopus 로고
    • Reactive oxygen intermediate(s) (ROI): common mediator(s) of poly(ADP-ribose) polymerase (PARP) cleavage and apoptosis
    • McGowan A.J., Ruiz-Ruiz M.C., Gorman A.M., Lopez-Rivas A., and Cotter T.G. Reactive oxygen intermediate(s) (ROI): common mediator(s) of poly(ADP-ribose) polymerase (PARP) cleavage and apoptosis. FEBS Letters 392 3 (1996) 299-303
    • (1996) FEBS Letters , vol.392 , Issue.3 , pp. 299-303
    • McGowan, A.J.1    Ruiz-Ruiz, M.C.2    Gorman, A.M.3    Lopez-Rivas, A.4    Cotter, T.G.5
  • 42
    • 0029007943 scopus 로고
    • Glutathione metabolism
    • Meister A. Glutathione metabolism. Methods Enzymology 251 (1995) 3-7
    • (1995) Methods Enzymology , vol.251 , pp. 3-7
    • Meister, A.1
  • 43
    • 0014757218 scopus 로고
    • Carcinogenesis by chemicals: an overview, G.H.A. Clowes Memorial Lecture
    • Miller J.A. Carcinogenesis by chemicals: an overview, G.H.A. Clowes Memorial Lecture. Cancer Research 30 (1970) 559-576
    • (1970) Cancer Research , vol.30 , pp. 559-576
    • Miller, J.A.1
  • 45
    • 0029776435 scopus 로고    scopus 로고
    • Chromosomes study as predictor of chemoresponse of tumours
    • Mourelatos D. Chromosomes study as predictor of chemoresponse of tumours. Cancer Journal 9 3 (1996) 136-141
    • (1996) Cancer Journal , vol.9 , Issue.3 , pp. 136-141
    • Mourelatos, D.1
  • 46
    • 0023872145 scopus 로고
    • Enhancement of cytogenetic damage and of antineoplastic effect by caffeine in Ehrlich ascites tumour cells treated with cyclophosphamide in vivo
    • Mourelatos D., Dozi-Vassiliades J., Kotsis A., and Goutsas C. Enhancement of cytogenetic damage and of antineoplastic effect by caffeine in Ehrlich ascites tumour cells treated with cyclophosphamide in vivo. Cancer Research 48 (1988) 1129-1131
    • (1988) Cancer Research , vol.48 , pp. 1129-1131
    • Mourelatos, D.1    Dozi-Vassiliades, J.2    Kotsis, A.3    Goutsas, C.4
  • 48
    • 0016328318 scopus 로고
    • New Giemsa method for the differential staining of sister chromatids
    • Perry P., and Wolf S. New Giemsa method for the differential staining of sister chromatids. Nature 251 (1974) 156-158
    • (1974) Nature , vol.251 , pp. 156-158
    • Perry, P.1    Wolf, S.2
  • 49
    • 0034769063 scopus 로고    scopus 로고
    • Ryanodine receptor acts as a sensor for redox stress
    • Pessah I.N. Ryanodine receptor acts as a sensor for redox stress. Pest Management Science 57 (2001) 941-945
    • (2001) Pest Management Science , vol.57 , pp. 941-945
    • Pessah, I.N.1
  • 50
    • 0034951105 scopus 로고    scopus 로고
    • Methylmercury neurotoxicity in cultures of human neurons, astrocytes, neuroblastoma cells
    • Sanfeliu C., Sebastia J., and Ki S.U. Methylmercury neurotoxicity in cultures of human neurons, astrocytes, neuroblastoma cells. Neurotoxicology 22 3 (2001) 317-327
    • (2001) Neurotoxicology , vol.22 , Issue.3 , pp. 317-327
    • Sanfeliu, C.1    Sebastia, J.2    Ki, S.U.3
  • 51
    • 0027194712 scopus 로고
    • 2+ and inositol phosphate levels in cultured cerebellar granule neurons
    • 2+ and inositol phosphate levels in cultured cerebellar granule neurons. Journal of Neurochemistry 61 (1993) 648-657
    • (1993) Journal of Neurochemistry , vol.61 , pp. 648-657
    • Sarafian, T.A.1
  • 54
    • 0032076667 scopus 로고    scopus 로고
    • Low level methylmercury exposure causes human T-cell to undergoing apoptosis: evidence of mitochondrial dysfunction
    • Shenker B.J., Guo T.L., and Shapiro I.M. Low level methylmercury exposure causes human T-cell to undergoing apoptosis: evidence of mitochondrial dysfunction. Environment Research 77 (1998) 149-159
    • (1998) Environment Research , vol.77 , pp. 149-159
    • Shenker, B.J.1    Guo, T.L.2    Shapiro, I.M.3
  • 55
    • 0033562940 scopus 로고    scopus 로고
    • Induction of apoptosis in human T-cells by methyl mercury: temporal relationship between mitochondrial dysfunction and loss of reductive reserve
    • Shenker B.J., Guo T.L., Insug O., and Shapiro I.M. Induction of apoptosis in human T-cells by methyl mercury: temporal relationship between mitochondrial dysfunction and loss of reductive reserve. Toxicology and Applied Pharmacology 157 (1999) 23-35
    • (1999) Toxicology and Applied Pharmacology , vol.157 , pp. 23-35
    • Shenker, B.J.1    Guo, T.L.2    Insug, O.3    Shapiro, I.M.4
  • 56
    • 11844288947 scopus 로고    scopus 로고
    • Review of the in vivo genotoxicity tests performed with styrene
    • Speit G., and Henderson L. Review of the in vivo genotoxicity tests performed with styrene. Mutation Research 589 (2005) 67-79
    • (2005) Mutation Research , vol.589 , pp. 67-79
    • Speit, G.1    Henderson, L.2
  • 57
    • 0029959717 scopus 로고    scopus 로고
    • DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite
    • Szabo C. DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite. Free Radical Biology and Medicine 21 6 (1996) 855-869
    • (1996) Free Radical Biology and Medicine , vol.21 , Issue.6 , pp. 855-869
    • Szabo, C.1
  • 58
    • 0030250252 scopus 로고    scopus 로고
    • Chromosome aberrations, micronuclei, aneuploidy,sister chromatid exchange, and cancer risk assessment
    • Tucker J.D., and Preston R.J. Chromosome aberrations, micronuclei, aneuploidy,sister chromatid exchange, and cancer risk assessment. Mutation Research 365 (1996) 147-159
    • (1996) Mutation Research , vol.365 , pp. 147-159
    • Tucker, J.D.1    Preston, R.J.2
  • 60
    • 11844295378 scopus 로고    scopus 로고
    • Flow-cytometric analysis on cytotoxic effect of thimerosal, a preservative in vaccines, on lymphocytes dissociated from rat thymic glands
    • Ueha-Ishibashi T., Oyama Y., Nakao H., Umebayashi C., Hirama S., Sakai Y., Ishida S., and Okano Y. Flow-cytometric analysis on cytotoxic effect of thimerosal, a preservative in vaccines, on lymphocytes dissociated from rat thymic glands. Toxicology in Vitro 19 (2005) 191-198
    • (2005) Toxicology in Vitro , vol.19 , pp. 191-198
    • Ueha-Ishibashi, T.1    Oyama, Y.2    Nakao, H.3    Umebayashi, C.4    Hirama, S.5    Sakai, Y.6    Ishida, S.7    Okano, Y.8
  • 61
    • 0037219973 scopus 로고    scopus 로고
    • Thimerosal induces micronuclei in the cytochalasin B block micronucleus test with human lymphocytes
    • Westphal G.A., Asgari S., Schulz T.G., Bünger J., Müler M., and Hallier E. Thimerosal induces micronuclei in the cytochalasin B block micronucleus test with human lymphocytes. Archives Toxicology 77 (2003) 50-55
    • (2003) Archives Toxicology , vol.77 , pp. 50-55
    • Westphal, G.A.1    Asgari, S.2    Schulz, T.G.3    Bünger, J.4    Müler, M.5    Hallier, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.