Mitochondrial dysfunction in sepsis;Physiopathologie mitochondriale et syndrome septique

Reanimation

Volumn 17, Issue 3, 2008, Pages 185-191

  Neviere R ^a  

^a UFR3S Pharmacie   (France)

Author keywords

Cellular respiration; Endotoxin; Mitochondria; Nitrogen monoxide; Sepsis

Indexed keywords

ADENOSINE DIPHOSPHATE; OXYGEN; PYRUVATE DEHYDROGENASE;

AEROBIC METABOLISM; APOPTOSIS; AUTOPHAGY; BIOGENESIS; CELL RESPIRATION; CELL STRUCTURE; CITRIC ACID CYCLE; DEATH; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVE SITE; HYPOXIA; MULTIPLE ORGAN FAILURE; OXYGEN SENSING; REGULATORY MECHANISM; SEPSIS; SHORT SURVEY;

EID: 41949117929     PISSN: 16240693     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reaurg.2008.01.009     Document Type: Short Survey

References (34)

1. Green D.R., and Kroemer G. The pathophysiology of mitochondrial cell death. Science 305 (2004) 626-629
2. Bernardi P., Krauskopf A., Basso E., Petronilli V., Blachly-Dyson E., Di Lisa F., et al. The mitochondrial permeability transition from in vitro artifact to disease target. FEBS J 273 (2006) 2077-2099
3. Taylor C.T. Mitochondria and cellular oxygen sensing in the HIF pathway. Biochem J 409 (2008) 19-26
4. Guzy R.D., and Schumacker P.T. Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. Exp Physiol 91 (2006) 807-819
5. Waypa G.B., and Schumacker P.T. Hypoxic pulmonary vasoconstriction: redox events in oxygen sensing. J Appl Physiol 98 (2005) 404-414
6. Semenza G.L. Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1. Biochem J 405 (2007) 1-9
7. Singer M., and Brealey D. Mitochondrial dysfunction in sepsis. Biochem Soc Symp 66 (1999) 149-166
8. Hayes M.A., Timmins A.C., Yau E.H., Palazzo M., Hinds C.J., and Watson D. Elevation of systemic oxygen delivery in the treatment of critically ill patients. N Engl J Med 330 (1994) 1717-1722
9. 2 Collaborative Group. N Engl J Med 333 (1995) 1025-1032
10. Schumer W., Das Gupta T.K., Moss G.S., and Nyhus L.M. Effect of endotoxemia on liver cell mitochondria in man. Ann Surg 171 (1970) 875-882
11. VanderMeer T.J., Wang H., and Fink M.P. Endotoxemia causes ileal mucosal acidosis in the absence of mucosal hypoxia in a normodynamic porcine model of septic shock. Crit Care Med 23 (1995) 1217-1226
12. Fink M.P. Bench-to-bedside review: Cytopathic hypoxia. Crit Care 6 (2002) 491-499
13. Singer M. Mitochondrial function in sepsis: acute phase versus multiple organ failure. Crit Care Med 35 (2007) S441-S448
14. Watts J.A., Kline J.A., Thornton L.R., Grattan R.M., and Brar S.S. Metabolic dysfunction and depletion of mitochondria in hearts of septic rats. J Mol Cell Cardiol 36 (2004) 141-150
15. Honzik T., Wenchich L., Bohm M., Hansikova H., Pejznochova M., Zapadlo M., et al. Activities of respiratory chain complexes and pyruvate dehydrogenase in isolated muscle mitochondria in premature neonates. Early Hum Dev (2007)
16. Vary T.C., and Hazen S. Sepsis alters pyruvate dehydrogenase kinase activity in skeletal muscle. Mol Cell Biochem 198 (1999) 113-118
17. Hotchkiss R.S., Song S.K., Neil J.J., Chen R.D., Manchester J.K., Karl I.E., et al. Sepsis does not impair tricarboxylic acid cycle in the heart. Am J Physiol 260 (1991) C50-C57
18. Mason K.E., and Stofan D.A. Endotoxin challenge reduces aconitase activity in myocardial tissue. Arch Biochem Biophys 469 (2008) 151-156
19. Kantrow S.P., Taylor D.E., Carraway M.S., and Piantadosi C.A. Oxidative metabolism in rat hepatocytes and mitochondria during sepsis. Arch Biochem Biophys 345 (1997) 278-288
20. Brealey D., Brand M., Hargreaves I., Heales S., Land J., Smolenski R., et al. Association between mitochondrial dysfunction and severity and outcome of septic shock. Lancet 360 (2002) 219-223
21. Brealey D., Karyampudi S., Jacques T.S., Novelli M., Stidwill R., Taylor V., et al. Mitochondrial dysfunction in a long-term rodent model of sepsis and organ failure. Am J Physiol Regul Integr Comp Physiol 286 (2004) R491-R497
22. Moriyama S., Okamoto K., Tabira Y., Kikuta K., Kukita I., Hamaguchi M., et al. Evaluation of oxygen consumption and resting energy expenditure in critically ill patients with systemic inflammatory response syndrome. Crit Care Med 27 (1999) 2133-2136
23. Fredriksson K., Hammarqvist F., Strigard K., Hultenby K., Ljungqvist O., Wernerman J., et al. Derangements in mitochondrial metabolism in intercostal and leg muscle of critically ill patients with sepsis-induced multiple organ failure. Am J Physiol Endocrinol Metab 291 (2006) E1044-E1050
24. Adrie C., Bachelet M., Vayssier-Taussat M., Russo-Marie F., Bouchaert I., Adib-Conquy M., et al. Mitochondrial membrane potential and apoptosis peripheral blood monocytes in severe human sepsis. Am J Respir Crit Care Med 164 (2001) 389-395
25. Belikova I., Lukaszewicz A.C., Faivre V., Damoisel C., Singer M., and Payen D. Oxygen consumption of human peripheral blood mononuclear cells in severe human sepsis. Crit Care Med 35 (2007) 2702-2708
26. Boulos M., Astiz M.E., Barua R.S., and Osman M. Impaired mitochondrial function induced by serum from septic shock patients is attenuated by inhibition of nitric oxide synthase and poly(ADP-ribose) synthase. Crit Care Med 31 (2003) 353-358
27. Brown G.C., and Borutaite V. Nitric oxide and mitochondrial respiration in the heart. Cardiovasc Res 75 (2007) 283-290
28. Moncada S., and Erusalimsky J.D. Does nitric oxide modulate mitochondrial energy generation and apoptosis?. Nat Rev Mol Cell Biol 3 (2002) 214-220
29. Erusalimsky J.D., and Moncada S. Nitric oxide and mitochondrial signaling: from physiology to pathophysiology. Arterioscler Thromb Vasc Biol 27 (2007) 2524-2531
30. Larche J., Lancel S., Hassoun S.M., Favory R., Decoster B., Marchetti P., et al. Inhibition of mitochondrial permeability transition prevents sepsis-induced myocardial dysfunction and mortality. J Am Coll Cardiol 48 (2006) 377-385
31. Callahan L.A., and Supinski G.S. Sepsis induces diaphragm electron transport chain dysfunction and protein depletion. Am J Respir Crit Care Med 172 (2005) 861-868
32. Callahan L.A., and Supinski G.S. Downregulation of diaphragm electron transport chain and glycolytic enzyme gene expression in sepsis. J Appl Physiol 99 (2005) 1120-1126
33. Suliman H.B., Welty-Wolf K.E., Carraway M., Tatro L., and Piantadosi C.A. Lipopolysaccharide induces oxidative cardiac mitochondrial damage and biogenesis. Cardiovasc Res 64 (2004) 279-288
34. Haden D.W., Suliman H.B., Carraway M.S., Welty-Wolf K.E., Ali A.S., Shitara H., et al. Mitochondrial biogenesis restores oxidative metabolism during Staphylococcus aureus sepsis. Am J Respir Crit Care Med 176 (2007) 768-777