-
1
-
-
2442590862
-
New drugs for rheumatoid arthritis
-
Olsen NJ, Stein CM. New drugs for rheumatoid arthritis. N Engl J Med 350: 2167-2179 (2004).
-
(2004)
N Engl J Med
, vol.350
, pp. 2167-2179
-
-
Olsen, N.J.1
Stein, C.M.2
-
3
-
-
33645737113
-
Gene therapy strategies towards immune tolerance to treat the autoimmune diseases
-
Siatskas C, Chan J, Field J, et al. Gene therapy strategies towards immune tolerance to treat the autoimmune diseases. Curr Gene Ther 6: 45-58 (2006).
-
(2006)
Curr Gene Ther
, vol.6
, pp. 45-58
-
-
Siatskas, C.1
Chan, J.2
Field, J.3
-
4
-
-
41849127691
-
Cytokine gene therapy for the treatment of rheumatoid arthritis
-
Eds Mazda O, Kerala, India, Research Signpost; pp
-
Woods JM, Koch AE. Cytokine gene therapy for the treatment of rheumatoid arthritis. In: Eds Mazda O, Immuno-gene Therapy. Kerala, India, Research Signpost; pp 141-172 (2004).
-
(2004)
Immuno-gene Therapy
, pp. 141-172
-
-
Woods, J.M.1
Koch, A.E.2
-
5
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
Hacein-Bey-Abina S, Von Kalle C, Schmidt M, et al. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302: 415-419 (2003).
-
(2003)
Science
, vol.302
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
-
7
-
-
33646474112
-
Gene therapeutic approaches-transfer in vivo
-
Evans CH, Gouze E, Gouze JN, Robbins PD, Ghivizzani SC. Gene therapeutic approaches-transfer in vivo. Adv Drug Deliv Rev 58: 243-258 (2006).
-
(2006)
Adv Drug Deliv Rev
, vol.58
, pp. 243-258
-
-
Evans, C.H.1
Gouze, E.2
Gouze, J.N.3
Robbins, P.D.4
Ghivizzani, S.C.5
-
8
-
-
33646836119
-
Technology insight: Gene transfer and the design of novel treatments for rheumatoid arthritis
-
Moritz F, Distler O, Ospelt C, Gay RE, Gay S. Technology insight: gene transfer and the design of novel treatments for rheumatoid arthritis. Nat Clin Pract Rheumatol 2: 153-162 (2006).
-
(2006)
Nat Clin Pract Rheumatol
, vol.2
, pp. 153-162
-
-
Moritz, F.1
Distler, O.2
Ospelt, C.3
Gay, R.E.4
Gay, S.5
-
9
-
-
31144475853
-
Developing the concept of adoptive cellular gene therapy of rheumatoid arthritis
-
Tarner IH, Neumann E, Gay S, Fathman CG, Muller-Ladner U. Developing the concept of adoptive cellular gene therapy of rheumatoid arthritis. Autoimmun Rev 5: 148-152 (2006).
-
(2006)
Autoimmun Rev
, vol.5
, pp. 148-152
-
-
Tarner, I.H.1
Neumann, E.2
Gay, S.3
Fathman, C.G.4
Muller-Ladner, U.5
-
10
-
-
1142273140
-
Gene therapy of collagen-induced arthritis by electrotransfer of human tumor necrosis factor-alpha soluble receptor I variants
-
Bloquel C, Bessis N, Boissier MC, Scherman D, Bigey P. Gene therapy of collagen-induced arthritis by electrotransfer of human tumor necrosis factor-alpha soluble receptor I variants. Hum Gene Ther 15: 189-201 (2004).
-
(2004)
Hum Gene Ther
, vol.15
, pp. 189-201
-
-
Bloquel, C.1
Bessis, N.2
Boissier, M.C.3
Scherman, D.4
Bigey, P.5
-
11
-
-
33747094421
-
Adenoviral delivery of IL-1 receptor antagonist abrogates disease activity during the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice
-
Hur W, Cho ML, Yoon SK, et al. Adenoviral delivery of IL-1 receptor antagonist abrogates disease activity during the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice. Immunol Lett 106: 154-162 (2006).
-
(2006)
Immunol Lett
, vol.106
, pp. 154-162
-
-
Hur, W.1
Cho, M.L.2
Yoon, S.K.3
-
12
-
-
0042878548
-
Protection against collagen-induced arthritis by intramuscular gene therapy with an expression plasmid for the interleukin-1 receptor antagonist
-
Kim JM, Jeong JG, Ho SH, et al. Protection against collagen-induced arthritis by intramuscular gene therapy with an expression plasmid for the interleukin-1 receptor antagonist. Gene Ther 10: 1543-1550 (2003).
-
(2003)
Gene Ther
, vol.10
, pp. 1543-1550
-
-
Kim, J.M.1
Jeong, J.G.2
Ho, S.H.3
-
13
-
-
22244474304
-
Soluble interleukin-1 receptor accessory protein ameliorates collagen-induced arthritis by a different mode of action from that of interleukin-1 receptor antagonist
-
Smeets RL, Joosten LA, Arntz OJ, et al. Soluble interleukin-1 receptor accessory protein ameliorates collagen-induced arthritis by a different mode of action from that of interleukin-1 receptor antagonist. Arthritis Rheum 52: 2202-2211 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2202-2211
-
-
Smeets, R.L.1
Joosten, L.A.2
Arntz, O.J.3
-
14
-
-
0142040402
-
Effectiveness of the soluble form of the interleukin-1 receptor accessory protein as an inhibitor of interleukin-1 in collagen-induced arthritis
-
Smeets RL, van de Loo FA, Joosten LA, et al. Effectiveness of the soluble form of the interleukin-1 receptor accessory protein as an inhibitor of interleukin-1 in collagen-induced arthritis. Arthritis Rheum 48: 2949-2958 (2003).
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2949-2958
-
-
Smeets, R.L.1
van de Loo, F.A.2
Joosten, L.A.3
-
15
-
-
0041672196
-
Localized expression of an anti-TNF single-chain antibody prevents development of collagen-induced arthritis
-
Smith R, Tarner IH, Hollenhorst M, et al. Localized expression of an anti-TNF single-chain antibody prevents development of collagen-induced arthritis. Gene Ther 10: 1248-1257 (2003).
-
(2003)
Gene Ther
, vol.10
, pp. 1248-1257
-
-
Smith, R.1
Tarner, I.H.2
Hollenhorst, M.3
-
16
-
-
0038685647
-
Adenoviral delivery of IL-18 binding protein C ameliorates collagen-induced arthritis in mice
-
Smeets RL, van de Loo FA, Arntz OJ, et al. Adenoviral delivery of IL-18 binding protein C ameliorates collagen-induced arthritis in mice. Gene Ther 10: 1004-1011 (2003).
-
(2003)
Gene Ther
, vol.10
, pp. 1004-1011
-
-
Smeets, R.L.1
van de Loo, F.A.2
Arntz, O.J.3
-
17
-
-
0035071329
-
Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu
-
Nakanishi K, Yoshimoto T, Tsutsui H, Okamura H. Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu. Cytokine Growth Factor Rev 12: 53-72 (2001).
-
(2001)
Cytokine Growth Factor Rev
, vol.12
, pp. 53-72
-
-
Nakanishi, K.1
Yoshimoto, T.2
Tsutsui, H.3
Okamura, H.4
-
18
-
-
20244372659
-
Inhibition of adjuvant-induced arthritis by systemic tissue inhibitor of metalloproteinases 4 gene delivery
-
Celiker MY, Ramamurthy N, Xu JW, et al. Inhibition of adjuvant-induced arthritis by systemic tissue inhibitor of metalloproteinases 4 gene delivery. Arthritis Rheum 46: 3361-3368 (2002).
-
(2002)
Arthritis Rheum
, vol.46
, pp. 3361-3368
-
-
Celiker, M.Y.1
Ramamurthy, N.2
Xu, J.W.3
-
19
-
-
26444593757
-
Local IL-13 gene transfer prior to immune-complex arthritis inhibits chondrocyte death and matrix-metalloproteinase-mediated cartilage matrix degradation despite enhanced joint inflammation
-
Nabbe KC, van Lent PL, Holthuysen AE, et al. Local IL-13 gene transfer prior to immune-complex arthritis inhibits chondrocyte death and matrix-metalloproteinase-mediated cartilage matrix degradation despite enhanced joint inflammation. Arthritis Res Ther 7: R392-401 (2005).
-
(2005)
Arthritis Res Ther
, vol.7
-
-
Nabbe, K.C.1
van Lent, P.L.2
Holthuysen, A.E.3
-
20
-
-
22244472310
-
Retroviral gene transfer of an antisense construct against membrane type 1 matrix metalloprotemase reduces the invasiveness of rheumatoid arthritis synovial fibroblasts
-
Rutkauskaite E, Volkmer D, Shigeyama Y, et al. Retroviral gene transfer of an antisense construct against membrane type 1 matrix metalloprotemase reduces the invasiveness of rheumatoid arthritis synovial fibroblasts. Arthritis Rheum 52: 2010-2014 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2010-2014
-
-
Rutkauskaite, E.1
Volkmer, D.2
Shigeyama, Y.3
-
21
-
-
2342548184
-
Ribozymes that inhibit the production of matrix metalloproteinase 1 reduce the invasiveness of rheumatoid arthritis synovial fibroblasts
-
Rutkauskaite E, Zacharias W, Schedel J, et al. Ribozymes that inhibit the production of matrix metalloproteinase 1 reduce the invasiveness of rheumatoid arthritis synovial fibroblasts. Arthritis Rheum 50: 1448-1456 (2004).
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1448-1456
-
-
Rutkauskaite, E.1
Zacharias, W.2
Schedel, J.3
-
22
-
-
3242801365
-
Targeting cathepsin L (CL) by specific ribozymes decreases CL protein synthesis and cartilage destruction in rheumatoid arthritis
-
Schedel J, Seemayer CA, Pap T, et al. Targeting cathepsin L (CL) by specific ribozymes decreases CL protein synthesis and cartilage destruction in rheumatoid arthritis. Gene Ther 11: 1040-1047 (2004).
-
(2004)
Gene Ther
, vol.11
, pp. 1040-1047
-
-
Schedel, J.1
Seemayer, C.A.2
Pap, T.3
-
23
-
-
0037319185
-
Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3
-
van der Laan WH, Quax PH, Seemayer CA, et al. Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3. Gene Ther 10: 234-242 (2003).
-
(2003)
Gene Ther
, vol.10
, pp. 234-242
-
-
van der Laan, W.H.1
Quax, P.H.2
Seemayer, C.A.3
-
24
-
-
0036206957
-
Interleukin-13 gene therapy reduces inflammation, vascularization, and bony destruction in rat adjuvant-induced arthritis
-
Woods JM, Amin MA, Katschke KJ, Jr., et al. Interleukin-13 gene therapy reduces inflammation, vascularization, and bony destruction in rat adjuvant-induced arthritis. Hum Gene Ther 13: 381-393 (2002).
-
(2002)
Hum Gene Ther
, vol.13
, pp. 381-393
-
-
Woods, J.M.1
Amin, M.A.2
Katschke Jr., K.J.3
-
25
-
-
0034284226
-
Reduction of inflammatory cytokines and prostaglandin E2 by IL-13 gene therapy in rheumatoid arthritis synovium
-
Woods JM, Katschke KJ, Jr., Tokuhira M, et al. Reduction of inflammatory cytokines and prostaglandin E2 by IL-13 gene therapy in rheumatoid arthritis synovium. J Immunol 165: 2755-2763 (2000).
-
(2000)
J Immunol
, vol.165
, pp. 2755-2763
-
-
Woods, J.M.1
Katschke Jr., K.J.2
Tokuhira, M.3
-
26
-
-
34547770721
-
In vivo inhibition of angiogenesis by interleukin-13 gene therapy in a rat model of rheumatoid arthritis
-
Haas CS, Amin MA, Ruth JH, et al. In vivo inhibition of angiogenesis by interleukin-13 gene therapy in a rat model of rheumatoid arthritis. Arthritis Rheum 56: 2535-2548 (2007).
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2535-2548
-
-
Haas, C.S.1
Amin, M.A.2
Ruth, J.H.3
-
27
-
-
0242319672
-
Adenoviral delivery of soluble VEGF receptor 1 (sFIt-1) abrogates disease activity in murine collagen-induced arthritis
-
Afuwape AO, Feldmann M, Paleolog EM. Adenoviral delivery of soluble VEGF receptor 1 (sFIt-1) abrogates disease activity in murine collagen-induced arthritis. Gene Ther 10: 1950-1960 (2003).
-
(2003)
Gene Ther
, vol.10
, pp. 1950-1960
-
-
Afuwape, A.O.1
Feldmann, M.2
Paleolog, E.M.3
-
28
-
-
18644372654
-
Gene therapy targeting the Tie2 function ameliorates collagen-induced arthritis and protects against bone destruction
-
Chen Y, Donnelly E, Kobayashi H, Debusk LM, Lin PC. Gene therapy targeting the Tie2 function ameliorates collagen-induced arthritis and protects against bone destruction. Arthritis Rheum 52: 1585-1594 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1585-1594
-
-
Chen, Y.1
Donnelly, E.2
Kobayashi, H.3
Debusk, L.M.4
Lin, P.C.5
-
29
-
-
33747026687
-
Inhibition of angiogenesis by interleukin-4 gene therapy in rat adjuvant-induced arthritis
-
Haas CS, Amin MA, Allen BB, et al. Inhibition of angiogenesis by interleukin-4 gene therapy in rat adjuvant-induced arthritis. Arthritis Rheum 54: 2402-2414 (2006).
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2402-2414
-
-
Haas, C.S.1
Amin, M.A.2
Allen, B.B.3
-
30
-
-
12344331258
-
Thrombospondin 1 as an effective gene therapeutic strategy in collagen-induced arthritis
-
Jou IM, Shiau AL, Chen SY, et al. Thrombospondin 1 as an effective gene therapeutic strategy in collagen-induced arthritis. Arthritis Rheum 52: 339-344 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 339-344
-
-
Jou, I.M.1
Shiau, A.L.2
Chen, S.Y.3
-
31
-
-
25144487618
-
Human immunodeficiency virus vector-mediated intra-articular expression of angiostatin inhibits progression of collagen-induced arthritis in mice
-
Kato K, Miyake K, Igarashi T, Yoshino S, Shimada T. Human immunodeficiency virus vector-mediated intra-articular expression of angiostatin inhibits progression of collagen-induced arthritis in mice. Rheumatol Int 25: 522-529 (2005).
-
(2005)
Rheumatol Int
, vol.25
, pp. 522-529
-
-
Kato, K.1
Miyake, K.2
Igarashi, T.3
Yoshino, S.4
Shimada, T.5
-
32
-
-
26844498412
-
Adeno-associated virus vector-mediated anti-angiogenic gene therapy for collagen-induced arthritis in mice
-
Takahashi H, Kato K, Miyake K, et al. Adeno-associated virus vector-mediated anti-angiogenic gene therapy for collagen-induced arthritis in mice. Clin Exp Rbeumatol 23: 455-461 (2005).
-
(2005)
Clin Exp Rbeumatol
, vol.23
, pp. 455-461
-
-
Takahashi, H.1
Kato, K.2
Miyake, K.3
-
33
-
-
17244372754
-
Prophylactic adenovirus-mediated human kallistatin gene therapy suppresses rat arthritis by inhibiting angiogenesis and inflammation
-
Wang CR, Chen SY, Wu CL, et al. Prophylactic adenovirus-mediated human kallistatin gene therapy suppresses rat arthritis by inhibiting angiogenesis and inflammation. Arthritis Rheum 52: 1319-1324 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1319-1324
-
-
Wang, C.R.1
Chen, S.Y.2
Wu, C.L.3
-
34
-
-
0032555937
-
Inhibition of angiogenesis by interleukin 4
-
Volpert OV, Fong T, Koch AE, et al. Inhibition of angiogenesis by interleukin 4. J Exp Med 188: 1039-1046 (1998).
-
(1998)
J Exp Med
, vol.188
, pp. 1039-1046
-
-
Volpert, O.V.1
Fong, T.2
Koch, A.E.3
-
35
-
-
0035863813
-
IL-4 adenoviral gene therapy reduces inflammation, proinflammatory cytokines, vascularization, and bony destruction in rat adjuvant-induced arthritis
-
Woods JM, Katschke KJ, Volin MV, et al. IL-4 adenoviral gene therapy reduces inflammation, proinflammatory cytokines, vascularization, and bony destruction in rat adjuvant-induced arthritis. J Immunol 166: 1214-1222 (2001).
-
(2001)
J Immunol
, vol.166
, pp. 1214-1222
-
-
Woods, J.M.1
Katschke, K.J.2
Volin, M.V.3
-
36
-
-
34247637682
-
Interleukin-4 induces human hepatocyte apoptosis through a Fas-independent pathway
-
Aoudjehane L, Podevin P, Scatton O, et al. Interleukin-4 induces human hepatocyte apoptosis through a Fas-independent pathway. FASEB J 21: 1433-1444 (2007).
-
(2007)
FASEB J
, vol.21
, pp. 1433-1444
-
-
Aoudjehane, L.1
Podevin, P.2
Scatton, O.3
-
37
-
-
0035871842
-
Lethal hepatitis after gene transfer of IL-4 in the liver is independent of immune responses and dependent on apoptosis of hepatocytes: A rodent model of IL-4-induced hepatitis
-
Guillot C, Coathalem H, Chetritt J, et al. Lethal hepatitis after gene transfer of IL-4 in the liver is independent of immune responses and dependent on apoptosis of hepatocytes: a rodent model of IL-4-induced hepatitis. J Immunol 166: 5225-5235 (2001).
-
(2001)
J Immunol
, vol.166
, pp. 5225-5235
-
-
Guillot, C.1
Coathalem, H.2
Chetritt, J.3
-
38
-
-
0034641107
-
Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3
-
Hotary K, Allen E, Punturieri A, Yana I, Weiss SJ. Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3. J Cell Biol 149: 1309-1323 (2000).
-
(2000)
J Cell Biol
, vol.149
, pp. 1309-1323
-
-
Hotary, K.1
Allen, E.2
Punturieri, A.3
Yana, I.4
Weiss, S.J.5
-
40
-
-
33646367148
-
Regulatory role of heme oxygenase 1 in inflammation of rheumatoid arthritis
-
Kobayashi H, Takeno M, Saito T, et al. Regulatory role of heme oxygenase 1 in inflammation of rheumatoid arthritis. Arthritis Rheum 54: 1132-1142 (2006).
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1132-1142
-
-
Kobayashi, H.1
Takeno, M.2
Saito, T.3
-
41
-
-
0036414453
-
Heme oxygenase 1 mediates the immunomodulatory and antiapoptotic effects of interleukin 13 gene therapy in vivo and in vitro
-
Ke B, Shen XD, Zhai Y, et al. Heme oxygenase 1 mediates the immunomodulatory and antiapoptotic effects of interleukin 13 gene therapy in vivo and in vitro. Hum Gene Ther 13: 1845-1857 (2002).
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1845-1857
-
-
Ke, B.1
Shen, X.D.2
Zhai, Y.3
-
42
-
-
0035258397
-
Apoptosis and rheumatoid arthritis: Past, present, and future directions
-
Mountz JD, Hsu HC, Matsuki Y, Zhang HG. Apoptosis and rheumatoid arthritis: past, present, and future directions. Curr Rheumatol Rep 3: 70-78 (2001).
-
(2001)
Curr Rheumatol Rep
, vol.3
, pp. 70-78
-
-
Mountz, J.D.1
Hsu, H.C.2
Matsuki, Y.3
Zhang, H.G.4
-
43
-
-
0031020293
-
Accumulation of soluble Fas in inflamed joints of patients with rheumatoid arthritis
-
Hasunuma T, Kayagaki N, Asahara H, et al. Accumulation of soluble Fas in inflamed joints of patients with rheumatoid arthritis. Arthritis Rheum 40: 80-86 (1997).
-
(1997)
Arthritis Rheum
, vol.40
, pp. 80-86
-
-
Hasunuma, T.1
Kayagaki, N.2
Asahara, H.3
-
44
-
-
0033456158
-
FLICE-inhibitory protein expression during macrophage differentiation confers resistance to fas-mediated apoptosis
-
Perlman H, Pagliari LJ, Georganas C, et al. FLICE-inhibitory protein expression during macrophage differentiation confers resistance to fas-mediated apoptosis. J Exp Med 190: 1679-1688 (1999).
-
(1999)
J Exp Med
, vol.190
, pp. 1679-1688
-
-
Perlman, H.1
Pagliari, L.J.2
Georganas, C.3
-
45
-
-
33644668415
-
Elimination of rheumatoid synovium in situ using a Fas ligand 'gene scalpel'
-
Zhang H, Gao G, Clayburne G, Schumacher HR. Elimination of rheumatoid synovium in situ using a Fas ligand 'gene scalpel'. Arthritis Res Ther 7: R1235-1243 (2005).
-
(2005)
Arthritis Res Ther
, vol.7
-
-
Zhang, H.1
Gao, G.2
Clayburne, G.3
Schumacher, H.R.4
-
46
-
-
0036851270
-
Effective treatment of established mouse collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express FasL
-
Kim SH, Kim S, Oligino TJ, Robbins PD. Effective treatment of established mouse collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express FasL. Mol Ther 6: 584-590 (2002).
-
(2002)
Mol Ther
, vol.6
, pp. 584-590
-
-
Kim, S.H.1
Kim, S.2
Oligino, T.J.3
Robbins, P.D.4
-
47
-
-
0346969979
-
CII-DC-AdTRAIL cell gene therapy inhibits infiltration of CII-reactive T cells and CII-induced arthritis
-
Liu Z, Xu X, Hsu HC, et al. CII-DC-AdTRAIL cell gene therapy inhibits infiltration of CII-reactive T cells and CII-induced arthritis. J Clin Invest 112: 1332-1341 (2003).
-
(2003)
J Clin Invest
, vol.112
, pp. 1332-1341
-
-
Liu, Z.1
Xu, X.2
Hsu, H.C.3
-
48
-
-
0037670222
-
Intra-articular adenoviral-mediated gene transfer of trail induces apoptosis of arthritic rabbit synovium
-
Yao Q, Wang S, Gambotto A, et al. Intra-articular adenoviral-mediated gene transfer of trail induces apoptosis of arthritic rabbit synovium. Gene Ther 10: 1055-1060 (2003).
-
(2003)
Gene Ther
, vol.10
, pp. 1055-1060
-
-
Yao, Q.1
Wang, S.2
Gambotto, A.3
-
50
-
-
0034942860
-
-
Makarov SS. NF-kappa B in rheumatoid arthritis: a pivotal regulator of inflammation, hyperplasia, and tissue destruction. Arthritis Res 3: 200-206 (2001).
-
Makarov SS. NF-kappa B in rheumatoid arthritis: a pivotal regulator of inflammation, hyperplasia, and tissue destruction. Arthritis Res 3: 200-206 (2001).
-
-
-
-
51
-
-
0032505870
-
NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint
-
Miagkov AV, Kovalenko DV, Brown CE, et al. NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint. Proc Natl Acad Sci U S A 95: 13859-13864 (1998).
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13859-13864
-
-
Miagkov, A.V.1
Kovalenko, D.V.2
Brown, C.E.3
-
52
-
-
0030758946
-
NF-kappa B as a target for anti-inflammatory gene therapy: Suppression of inflammatory responses in monocytic and stromal cells by stable gene transfer of I kappa B alpha cDNA
-
Makarov SS, Johnston WN, Olsen JC, et al. NF-kappa B as a target for anti-inflammatory gene therapy: suppression of inflammatory responses in monocytic and stromal cells by stable gene transfer of I kappa B alpha cDNA. Gene Ther 4: 846-852 (1997).
-
(1997)
Gene Ther
, vol.4
, pp. 846-852
-
-
Makarov, S.S.1
Johnston, W.N.2
Olsen, J.C.3
-
53
-
-
33750577799
-
Amelioration of arthritis by intraarticular dominant negative Ikk beta gene therapy using adeno-associated virus type 5
-
Tas SW, Adriaansen J, Hajji N, et al. Amelioration of arthritis by intraarticular dominant negative Ikk beta gene therapy using adeno-associated virus type 5. Hum Gene Ther 17: 821-832 (2006).
-
(2006)
Hum Gene Ther
, vol.17
, pp. 821-832
-
-
Tas, S.W.1
Adriaansen, J.2
Hajji, N.3
-
54
-
-
0033758633
-
Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis
-
Schett G, Tohidast-Akrad M, Smolen JS, et al. Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis. Arthritis Rheum 43: 2501-2512 (2000).
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2501-2512
-
-
Schett, G.1
Tohidast-Akrad, M.2
Smolen, J.S.3
-
55
-
-
0032541650
-
Increasing complexity of Ras signaling
-
Campbell SL, Khosravi-Far R, Rossman KL, Clark GJ, Der CJ. Increasing complexity of Ras signaling. Oncogene 17: 1395-1413 (1998).
-
(1998)
Oncogene
, vol.17
, pp. 1395-1413
-
-
Campbell, S.L.1
Khosravi-Far, R.2
Rossman, K.L.3
Clark, G.J.4
CJ, D.5
-
56
-
-
0029862818
-
Oncoprotein expression in human synovial tissue: An immunohistochemical study of different types of arthritis
-
Roivainen A, Soderstrom KO, Pirila L, et al. Oncoprotein expression in human synovial tissue: an immunohistochemical study of different types of arthritis. Br J Rbeumatol 35: 933-942 (1996).
-
(1996)
Br J Rbeumatol
, vol.35
, pp. 933-942
-
-
Roivainen, A.1
Soderstrom, K.O.2
Pirila, L.3
-
57
-
-
0141564912
-
Suppression of arthritic bone destruction by adenovirus-mediated dominant-negative Ras gene transfer to synoviocytes and osteoclasts
-
Yamamoto A, Fukuda A, Seto H, et al. Suppression of arthritic bone destruction by adenovirus-mediated dominant-negative Ras gene transfer to synoviocytes and osteoclasts. Arthritis Rheum 48: 2682-2692 (2003).
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2682-2692
-
-
Yamamoto, A.1
Fukuda, A.2
Seto, H.3
-
58
-
-
0036579839
-
Syngeneic fibroblasts transfected with a plasmid encoding interleukin-4 as non-viral vectors for anti-inflammatory gene therapy in collagen-induced arthritis
-
Bessis N, Cottard V, Saidenberg-Kermanach N, et al. Syngeneic fibroblasts transfected with a plasmid encoding interleukin-4 as non-viral vectors for anti-inflammatory gene therapy in collagen-induced arthritis. J Gene Med 4: 300-307 (2002).
-
(2002)
J Gene Med
, vol.4
, pp. 300-307
-
-
Bessis, N.1
Cottard, V.2
Saidenberg-Kermanach, N.3
-
59
-
-
1542313922
-
Plasmid encoding interleukin-4 in the amelioration of murine collagen-induced arthritis
-
Kageyama Y, Koide Y, Uchijima M, et al. Plasmid encoding interleukin-4 in the amelioration of murine collagen-induced arthritis. Arthritis Rheum 50: 968-975 (2004).
-
(2004)
Arthritis Rheum
, vol.50
, pp. 968-975
-
-
Kageyama, Y.1
Koide, Y.2
Uchijima, M.3
-
60
-
-
3442877945
-
Interleukin-4 cellular gene therapy and osteoprotegerin decrease inflammation-associated bone resorption in collagen-induced arthritis
-
Saidenberg-Kermanac'h N, Bessis N, Lemeiter D, et al. Interleukin-4 cellular gene therapy and osteoprotegerin decrease inflammation-associated bone resorption in collagen-induced arthritis. J Clin Immunol 24: 370-378 (2004).
-
(2004)
J Clin Immunol
, vol.24
, pp. 370-378
-
-
Saidenberg-Kermanac'h, N.1
Bessis, N.2
Lemeiter, D.3
-
61
-
-
0036913264
-
Retroviral gene therapy of collagen-induced arthritis by local delivery of IL-4
-
Tamer IH, Nakajima A, Seroogy CM, et al. Retroviral gene therapy of collagen-induced arthritis by local delivery of IL-4. Clin Immunol 105: 304-314 (2002).
-
(2002)
Clin Immunol
, vol.105
, pp. 304-314
-
-
Tamer, I.H.1
Nakajima, A.2
Seroogy, C.M.3
-
62
-
-
26844511733
-
Deficient expression of interleukin-10 receptor alpha chain in rheumatoid arthritis synovium: Limitation of animal models of inflammation
-
Neidhart M, Jungel A, Ospelt C, et al. Deficient expression of interleukin-10 receptor alpha chain in rheumatoid arthritis synovium: limitation of animal models of inflammation. Arthritis Rheum 52: 3315-3318 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 3315-3318
-
-
Neidhart, M.1
Jungel, A.2
Ospelt, C.3
-
63
-
-
0037791929
-
Efficacy of interleukin-10 gene electrotransfer into skeletal muscle in mice with collagen-induced arthritis
-
Saidenberg-Kermanac'h N, Bessis N, Deleuze V, et al. Efficacy of interleukin-10 gene electrotransfer into skeletal muscle in mice with collagen-induced arthritis. J Gene Med 5: 164-171 (2003).
-
(2003)
J Gene Med
, vol.5
, pp. 164-171
-
-
Saidenberg-Kermanac'h, N.1
Bessis, N.2
Deleuze, V.3
-
64
-
-
33644677402
-
Effects of viral interleukin 10 introduced by in vivo electroporation on arthrogen-induced arthritis in mice
-
Kuroda T, Maruyama H, Shimotori M, et al. Effects of viral interleukin 10 introduced by in vivo electroporation on arthrogen-induced arthritis in mice. J Rheumatol 33: 455-462 (2006).
-
(2006)
J Rheumatol
, vol.33
, pp. 455-462
-
-
Kuroda, T.1
Maruyama, H.2
Shimotori, M.3
-
65
-
-
18744405989
-
Inhibition of cartilage destruction by double gene transfer of IL-lRa and IL-10 involves the activin pathway
-
Neumann E, Judex M, Kullmann F, et al. Inhibition of cartilage destruction by double gene transfer of IL-lRa and IL-10 involves the activin pathway. Gene Ther 9: 1508-1519 (2002).
-
(2002)
Gene Ther
, vol.9
, pp. 1508-1519
-
-
Neumann, E.1
Judex, M.2
Kullmann, F.3
-
66
-
-
33747813905
-
A comparative study on intra-articular versus systemic gene electrotransfer in experimental arthritis
-
Khoury M, Bigey P, Louis-Plence P, et al. A comparative study on intra-articular versus systemic gene electrotransfer in experimental arthritis. J Gene Med 8: 1027-1036 (2006).
-
(2006)
J Gene Med
, vol.8
, pp. 1027-1036
-
-
Khoury, M.1
Bigey, P.2
Louis-Plence, P.3
-
67
-
-
0036019191
-
Tetracycline-inducible interleukin-10 gene transfer mediated by an adeno-associated virus: Application to experimental arthritis
-
Apparailly F, Millet V, Noel D, et al. Tetracycline-inducible interleukin-10 gene transfer mediated by an adeno-associated virus: application to experimental arthritis. Hum Gene Ther 13: 1179-1188 (2002).
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1179-1188
-
-
Apparailly, F.1
Millet, V.2
Noel, D.3
-
68
-
-
0036436160
-
-
Deleuze V, Scherman D, Bureau ME. Interleukin-10 expression after intramuscular DNA electrotransfer: kinetic studies. Biochem Biophys Res Commun 299: 29-34 (2002).
-
Deleuze V, Scherman D, Bureau ME. Interleukin-10 expression after intramuscular DNA electrotransfer: kinetic studies. Biochem Biophys Res Commun 299: 29-34 (2002).
-
-
-
-
69
-
-
0032102995
-
Adenovirus-mediated transfer of viral IL-10 gene inhibits murine collagen-induced arthritis
-
Apparailly F, Verwaerde C, Jacquet C, et al. Adenovirus-mediated transfer of viral IL-10 gene inhibits murine collagen-induced arthritis. J Immunol 160: 5213-5220 (1998).
-
(1998)
J Immunol
, vol.160
, pp. 5213-5220
-
-
Apparailly, F.1
Verwaerde, C.2
Jacquet, C.3
-
70
-
-
0031059255
-
Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction
-
Joosten LA, Lubberts E, Durez P, et al. Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction. Arthritis Rheum 40: 249-260 (1997).
-
(1997)
Arthritis Rheum
, vol.40
, pp. 249-260
-
-
Joosten, L.A.1
Lubberts, E.2
Durez, P.3
-
71
-
-
0034141551
-
Viral IL-10 and soluble TNF receptor act synergistically to inhibit collagen-induced arthritis following adenovirus-mediated gene transfer
-
Kim KN, Watanabe S, Ma Y, et al. Viral IL-10 and soluble TNF receptor act synergistically to inhibit collagen-induced arthritis following adenovirus-mediated gene transfer. J Inummol 164: 1576-1581 (2000).
-
(2000)
J Inummol
, vol.164
, pp. 1576-1581
-
-
Kim, K.N.1
Watanabe, S.2
Ma, Y.3
-
72
-
-
0032146169
-
Inhibition of collagen-induced arthritis in mice by viral IL- 10 gene transfer
-
Ma Y, Thornton S, Duwel LE, et al. Inhibition of collagen-induced arthritis in mice by viral IL- 10 gene transfer. J Immunol 161: 1516-1524 (1998).
-
(1998)
J Immunol
, vol.161
, pp. 1516-1524
-
-
Ma, Y.1
Thornton, S.2
Duwel, L.E.3
-
73
-
-
0035873071
-
Murine IL-10 gene transfer inhibits established collagen-induced arthritis and reduces adenovirus-mediated inflammatory responses in mouse liver
-
Quattrocchi E, Dallman MJ, Dhillon AP, et al. Murine IL-10 gene transfer inhibits established collagen-induced arthritis and reduces adenovirus-mediated inflammatory responses in mouse liver. J Immunol 166: 5970-5978 (2001).
-
(2001)
J Immunol
, vol.166
, pp. 5970-5978
-
-
Quattrocchi, E.1
Dallman, M.J.2
Dhillon, A.P.3
-
74
-
-
0033559906
-
Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws
-
Whalen JD, Lechman EL, Carlos CA, et al. Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws. J Immunol 162: 3625-3632 (1999).
-
(1999)
J Immunol
, vol.162
, pp. 3625-3632
-
-
Whalen, J.D.1
Lechman, E.L.2
Carlos, C.A.3
-
75
-
-
0347264779
-
Tetracycline transcriptional silencer tightly controls transgene expression after in vivo intramuscular electrotransfer: Application to interleukin 10 therapy in experimental arthritis
-
Perez N, Plence P, Millet V, et al. Tetracycline transcriptional silencer tightly controls transgene expression after in vivo intramuscular electrotransfer: application to interleukin 10 therapy in experimental arthritis. Hum Gene Ther 13: 2161-2172 (2002).
-
(2002)
Hum Gene Ther
, vol.13
, pp. 2161-2172
-
-
Perez, N.1
Plence, P.2
Millet, V.3
-
76
-
-
0034463305
-
Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group
-
Fedorak RN, Gangl A, Elson CO, et al. Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group. Gastroenterology 119: 1473-1482 (2000).
-
(2000)
Gastroenterology
, vol.119
, pp. 1473-1482
-
-
Fedorak, R.N.1
Gangl, A.2
Elson, C.O.3
-
77
-
-
0031697062
-
IL-10 as a therapeutic strategy in the treatment of rheumatoid arthritis
-
Keystone E, Wherry J, Grint P. IL-10 as a therapeutic strategy in the treatment of rheumatoid arthritis. Rheum Dis Clin North Am 24: 629-639 (1998).
-
(1998)
Rheum Dis Clin North Am
, vol.24
, pp. 629-639
-
-
Keystone, E.1
Wherry, J.2
Grint, P.3
-
78
-
-
0037103231
-
Role of IL-10 for induction of anemia during inflammation
-
Tilg H, Ulmer H, Kaser A, Weiss G. Role of IL-10 for induction of anemia during inflammation. J Inummol 169: 2204-2209 (2002).
-
(2002)
J Inummol
, vol.169
, pp. 2204-2209
-
-
Tilg, H.1
Ulmer, H.2
Kaser, A.3
Weiss, G.4
-
79
-
-
29144495959
-
Immune modulation of collagen-induced arthritis by intranasal cytokine gene delivery: A model for the therapy of rheumatoid arthritis
-
Woods AM, Thompson SJ, Wooley PH, Panayi G, Klavinskis LS. Immune modulation of collagen-induced arthritis by intranasal cytokine gene delivery: a model for the therapy of rheumatoid arthritis. Arthritis Rheum 52: 3761-3771 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 3761-3771
-
-
Woods, A.M.1
Thompson, S.J.2
Wooley, P.H.3
Panayi, G.4
Klavinskis, L.S.5
-
80
-
-
33846903340
-
Engraftment of cutaneous fibroblasts within synovial membrane in a nonhuman primate: Short-term results
-
Bessis N, Lemeiter D, Laroche L, et al. Engraftment of cutaneous fibroblasts within synovial membrane in a nonhuman primate: short-term results. Joint Bone Spine 74: 48-51 (2007).
-
(2007)
Joint Bone Spine
, vol.74
, pp. 48-51
-
-
Bessis, N.1
Lemeiter, D.2
Laroche, L.3
-
81
-
-
27144434561
-
Gene targeting by ribozyme against TNF-alpha mRNA inhibits autoimmune arthritis
-
Kumar R, Dammai V, Yadava PK, Kleinau S. Gene targeting by ribozyme against TNF-alpha mRNA inhibits autoimmune arthritis. Gene Ther 12: 1486-1493 (2005).
-
(2005)
Gene Ther
, vol.12
, pp. 1486-1493
-
-
Kumar, R.1
Dammai, V.2
Yadava, P.K.3
Kleinau, S.4
-
82
-
-
31644435920
-
A novel approach for gene therapy: Engraftment of fibroblasts containing the artificial chromosome expression system at the site of inflammation
-
Adriaansen J, Vervoordeldonk MJ, Vanderbyl S, de Jong G, Tak PP. A novel approach for gene therapy: engraftment of fibroblasts containing the artificial chromosome expression system at the site of inflammation. J Gene Med 8: 63-71 (2006).
-
(2006)
J Gene Med
, vol.8
, pp. 63-71
-
-
Adriaansen, J.1
Vervoordeldonk, M.J.2
Vanderbyl, S.3
de Jong, G.4
Tak, P.P.5
-
83
-
-
33645730405
-
Synthetic and natural polycations for gene therapy: State of the art and new perspectives
-
Tiera MJ, Winnik FO, Fernandes JC. Synthetic and natural polycations for gene therapy: state of the art and new perspectives. Curr Gene Ther 6: 59-71 (2006).
-
(2006)
Curr Gene Ther
, vol.6
, pp. 59-71
-
-
Tiera, M.J.1
Winnik, F.O.2
Fernandes, J.C.3
-
84
-
-
0037385083
-
Amelioration of antigen-induced arthritis in rats by transfer of extracellular superoxide dismutase and catalase genes
-
Dai L, Claxson A, Marklund SL, et al. Amelioration of antigen-induced arthritis in rats by transfer of extracellular superoxide dismutase and catalase genes. Gene Ther 10: 550-558 (2003).
-
(2003)
Gene Ther
, vol.10
, pp. 550-558
-
-
Dai, L.1
Claxson, A.2
Marklund, S.L.3
-
85
-
-
33847273537
-
Electrotransfer as a non viral method of gene delivery
-
Favard C, Dean DS, Rols MP. Electrotransfer as a non viral method of gene delivery. Curr Gene Ther 7: 67-77 (2007).
-
(2007)
Curr Gene Ther
, vol.7
, pp. 67-77
-
-
Favard, C.1
Dean, D.S.2
Rols, M.P.3
-
86
-
-
0034913116
-
Nonviral vectors in the new millennium: Delivery barriers in gene transfer
-
Nishikawa M, Huang L. Nonviral vectors in the new millennium: delivery barriers in gene transfer. Hum Gene Ther 12: 861-870 (2001).
-
(2001)
Hum Gene Ther
, vol.12
, pp. 861-870
-
-
Nishikawa, M.1
Huang, L.2
-
87
-
-
0037698989
-
Direct gene transfer into rat articular cartilage by in vivo electroporation
-
Grossin L, Cournil-Henrionnet C, Mir LM, et al. Direct gene transfer into rat articular cartilage by in vivo electroporation. FASEB J 17: 829-835 (2003).
-
(2003)
FASEB J
, vol.17
, pp. 829-835
-
-
Grossin, L.1
Cournil-Henrionnet, C.2
Mir, L.M.3
-
88
-
-
0033154484
-
Erythropoietin secretion and physiological effect in mouse after intramuscular plasmid DNA electrotransfer
-
Kreiss P, Bettan M, Crouzet J, Scherman D. Erythropoietin secretion and physiological effect in mouse after intramuscular plasmid DNA electrotransfer. J Gene Med 1: 245-250 (1999).
-
(1999)
J Gene Med
, vol.1
, pp. 245-250
-
-
Kreiss, P.1
Bettan, M.2
Crouzet, J.3
Scherman, D.4
-
89
-
-
0034628485
-
Continuous erythropoietin delivery by muscle-targeted gene transfer using in vivo electroporation
-
Maruyama H, Sugawa M, Moriguchi Y, et al. Continuous erythropoietin delivery by muscle-targeted gene transfer using in vivo electroporation. Hum Gene Ther 11: 429-437 (2000).
-
(2000)
Hum Gene Ther
, vol.11
, pp. 429-437
-
-
Maruyama, H.1
Sugawa, M.2
Moriguchi, Y.3
-
90
-
-
13044286785
-
-
Rizzuto G, Cappelletti M, Maione D, et al. Efficient and regulated erythropoietin production by naked DNA injection and muscle electroporation. Proc Nall Acad Sci U S A 96: 6417-6422 (1999).
-
Rizzuto G, Cappelletti M, Maione D, et al. Efficient and regulated erythropoietin production by naked DNA injection and muscle electroporation. Proc Nall Acad Sci U S A 96: 6417-6422 (1999).
-
-
-
-
91
-
-
2442593631
-
Inhibition of established collagen-induced arthritis with a tumour necrosis factor-alpha inhibitor expressed from a self-contained doxycycline regulated plasmid
-
Gould DJ, Bright C, Chernajovsky Y. Inhibition of established collagen-induced arthritis with a tumour necrosis factor-alpha inhibitor expressed from a self-contained doxycycline regulated plasmid. Arthritis Res Ther 6: R103-113 (2004).
-
(2004)
Arthritis Res Ther
, vol.6
-
-
Gould, D.J.1
Bright, C.2
Chernajovsky, Y.3
-
92
-
-
13644254726
-
Electrotransfer of human IL-1Ra into skeletal muscles reduces the incidence of murine collagen-induced arthritis
-
Jeong JG, Kim JM, Ho SH, et al. Electrotransfer of human IL-1Ra into skeletal muscles reduces the incidence of murine collagen-induced arthritis. J Gene Med 6: 1125-1133 (2004).
-
(2004)
J Gene Med
, vol.6
, pp. 1125-1133
-
-
Jeong, J.G.1
Kim, J.M.2
Ho, S.H.3
-
93
-
-
0042172871
-
Electro-gene therapy of collagen-induced arthritis by using an expression plasmid for the soluble p75 tumor necrosis factor receptor-Fc fusion protein
-
Kim JM, Ho SH, Hahn W, et al. Electro-gene therapy of collagen-induced arthritis by using an expression plasmid for the soluble p75 tumor necrosis factor receptor-Fc fusion protein. Gene Ther 10: 1216-1224 (2003).
-
(2003)
Gene Ther
, vol.10
, pp. 1216-1224
-
-
Kim, J.M.1
Ho, S.H.2
Hahn, W.3
-
94
-
-
4344717044
-
AAV vectors, the future workhorse of human gene therapy
-
Samulski RJ. AAV vectors, the future workhorse of human gene therapy. Ernst Schering Res Found Workshop 25-40 (2003).
-
(2003)
Ernst Schering Res Found Workshop
, vol.25-40
-
-
Samulski, R.J.1
-
95
-
-
21244451129
-
Adeno-associated viral vectors for clinical gene transfer studies
-
Snyder RO, Francis J. Adeno-associated viral vectors for clinical gene transfer studies. Curr Gene Ther 5: 311-321 (2005).
-
(2005)
Curr Gene Ther
, vol.5
, pp. 311-321
-
-
Snyder, R.O.1
Francis, J.2
-
96
-
-
0036968511
-
Adenovirus and adeno-associated virus vectors
-
Lai CM, Lai YK, Rakoczy PE. Adenovirus and adeno-associated virus vectors. DNA Cell Biol 21: 895-913 (2002).
-
(2002)
DNA Cell Biol
, vol.21
, pp. 895-913
-
-
Lai, C.M.1
Lai, Y.K.2
Rakoczy, P.E.3
-
97
-
-
0030850930
-
Lack of site-specific integration of the recombinant adeno-associated virus 2 genomes in human cells
-
Ponnazhagan S, Erikson D, Kearns WG, et al. Lack of site-specific integration of the recombinant adeno-associated virus 2 genomes in human cells. Hum Gene Ther 8: 275-284 (1997).
-
(1997)
Hum Gene Ther
, vol.8
, pp. 275-284
-
-
Ponnazhagan, S.1
Erikson, D.2
Kearns, W.G.3
-
98
-
-
0348038748
-
Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo
-
Wang Z, Ma HI, Li J, et al. Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo. Gene Ther 10: 2105-2111 (2003).
-
(2003)
Gene Ther
, vol.10
, pp. 2105-2111
-
-
Wang, Z.1
Ma, H.I.2
Li, J.3
-
99
-
-
0034041974
-
Gene delivery to human chondrocytes by an adeno associated virus vector
-
Arai Y, Kubo T, Fushiki S, et al. Gene delivery to human chondrocytes by an adeno associated virus vector. J Rheumatol 27: 979-982 (2000).
-
(2000)
J Rheumatol
, vol.27
, pp. 979-982
-
-
Arai, Y.1
Kubo, T.2
Fushiki, S.3
-
100
-
-
0037338160
-
Recombinant adeno-associated virus vectors efficiently and persistently transduce chondrocytes in normal and osteoarthritic human articular cartilage
-
Madry H, Cucchiarini M, Terwilliger EF, Trippel SB. Recombinant adeno-associated virus vectors efficiently and persistently transduce chondrocytes in normal and osteoarthritic human articular cartilage. Hum Gene Ther 14: 393-402 (2003).
-
(2003)
Hum Gene Ther
, vol.14
, pp. 393-402
-
-
Madry, H.1
Cucchiarini, M.2
Terwilliger, E.F.3
Trippel, S.B.4
-
101
-
-
2942596444
-
In vivo gene delivery to articular chondrocytes mediated by an adeno-associated virus vector
-
Ulrich-Vinther M, Duch MR, Soballe K, et al. In vivo gene delivery to articular chondrocytes mediated by an adeno-associated virus vector. J Orthop Res 22: 726-734 (2004).
-
(2004)
J Orthop Res
, vol.22
, pp. 726-734
-
-
Ulrich-Vinther, M.1
Duch, M.R.2
Soballe, K.3
-
102
-
-
0343618533
-
Empirical advantages of adeno associated viral vectors in vivo gene therapy for arthritis
-
Goater J, Muller R, Kollias G, et al. Empirical advantages of adeno associated viral vectors in vivo gene therapy for arthritis. J Rheumatol 27: 983-989 (2000).
-
(2000)
J Rheumatol
, vol.27
, pp. 983-989
-
-
Goater, J.1
Muller, R.2
Kollias, G.3
-
103
-
-
0034130299
-
Therapy and prevention of arthritis by recombinant adeno-associated virus vector with delivery of interleukin-1 receptor antagonist
-
Pan RY, Chen SL, Xiao X, et al. Therapy and prevention of arthritis by recombinant adeno-associated virus vector with delivery of interleukin-1 receptor antagonist. Arthritis Rheum 43: 289-297 (2000).
-
(2000)
Arthritis Rheum
, vol.43
, pp. 289-297
-
-
Pan, R.Y.1
Chen, S.L.2
Xiao, X.3
-
104
-
-
0033015013
-
Disease-inducible transgene expression from a recombinant adeno-associated virus vector in a rat arthritis model
-
Pan RY, Xiao X, Chen SL, et al. Disease-inducible transgene expression from a recombinant adeno-associated virus vector in a rat arthritis model. J Virol 73: 3410-3417 (1999).
-
(1999)
J Virol
, vol.73
, pp. 3410-3417
-
-
Pan, R.Y.1
Xiao, X.2
Chen, S.L.3
-
105
-
-
0034241592
-
Adeno-associated virus mediates long-term gene transfer and delivery of chondroprotective IL-4 to murine synovium
-
Watanabe S, Imagawa T, Boivin GP, et al. Adeno-associated virus mediates long-term gene transfer and delivery of chondroprotective IL-4 to murine synovium. Mol Ther 2: 147-152 (2000).
-
(2000)
Mol Ther
, vol.2
, pp. 147-152
-
-
Watanabe, S.1
Imagawa, T.2
Boivin, G.P.3
-
106
-
-
20144377839
-
Proteasome inhibition enhances AAV-mediated transgene expression in human synoviocytes in vitro and in vivo
-
Jennings K, Miyamae T, Traister R, et al. Proteasome inhibition enhances AAV-mediated transgene expression in human synoviocytes in vitro and in vivo. Mol Ther 11: 600-607 (2005).
-
(2005)
Mol Ther
, vol.11
, pp. 600-607
-
-
Jennings, K.1
Miyamae, T.2
Traister, R.3
-
107
-
-
0036936788
-
Intraarticular gene transfer of TNFR:Fc suppresses experimental arthritis with reduced systemic distribution of the gene product
-
Chan JM, Villarreal G, Jin WW, et al. Intraarticular gene transfer of TNFR:Fc suppresses experimental arthritis with reduced systemic distribution of the gene product. Mol Ther 6: 727-736 (2002).
-
(2002)
Mol Ther
, vol.6
, pp. 727-736
-
-
Chan, J.M.1
Villarreal, G.2
Jin, W.W.3
-
108
-
-
3142699127
-
Recombinant adeno-associated virus vectors for gene therapy
-
Conlon TJ, Flotte TR. Recombinant adeno-associated virus vectors for gene therapy. Expert Opin Biol Ther 4: 1093-1101 (2004).
-
(2004)
Expert Opin Biol Ther
, vol.4
, pp. 1093-1101
-
-
Conlon, T.J.1
Flotte, T.R.2
-
109
-
-
0032515968
-
Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects
-
Ghivizzani SC, Lechman ER, Kang R, et al. Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects. Proc Natl Acad Sci U S A 95: 4613-4618 (1998).
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 4613-4618
-
-
Ghivizzani, S.C.1
Lechman, E.R.2
Kang, R.3
-
110
-
-
0033566812
-
Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees
-
Lechman ER, Jaffurs D, Ghivizzani SC, et al. Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees. J Immunol 163: 2202-2208 (1999).
-
(1999)
J Immunol
, vol.163
, pp. 2202-2208
-
-
Lechman, E.R.1
Jaffurs, D.2
Ghivizzani, S.C.3
-
111
-
-
0033374353
-
Intra-articular IL-4 gene therapy in arthritis: Anti-inflammatory effect and enhanced th2activity
-
Boyle DL, Nguyen KH, Zhuang S, et al. Intra-articular IL-4 gene therapy in arthritis: anti-inflammatory effect and enhanced th2activity. Gene Ther 6: 1911-1918 (1999).
-
(1999)
Gene Ther
, vol.6
, pp. 1911-1918
-
-
Boyle, D.L.1
Nguyen, K.H.2
Zhuang, S.3
-
112
-
-
0036853027
-
Ex vivo gene delivery of IL-1Ra and soluble TNT receptor confers a distal synergistic therapeutic effect in antigen-induced arthritis
-
Kim SH, Lechman ER, Kim S, et al. Ex vivo gene delivery of IL-1Ra and soluble TNT receptor confers a distal synergistic therapeutic effect in antigen-induced arthritis. Mol Ther 6: 591-600 (2002).
-
(2002)
Mol Ther
, vol.6
, pp. 591-600
-
-
Kim, S.H.1
Lechman, E.R.2
Kim, S.3
-
113
-
-
0242693291
-
The contralateral effect conferred by intra-articular adenovirus-mediated gene transfer of viral IL-10 is specific to the immunizing antigen
-
Lechman ER, Keravala A, Nash J, et al. The contralateral effect conferred by intra-articular adenovirus-mediated gene transfer of viral IL-10 is specific to the immunizing antigen. Gene Ther 10: 2029-2035 (2003).
-
(2003)
Gene Ther
, vol.10
, pp. 2029-2035
-
-
Lechman, E.R.1
Keravala, A.2
Nash, J.3
-
114
-
-
20844458756
-
Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis
-
Kim SH, Lechman ER, Bianco N, et al. Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis. J Immunol 174: 6440-6448 (2005).
-
(2005)
J Immunol
, vol.174
, pp. 6440-6448
-
-
Kim, S.H.1
Lechman, E.R.2
Bianco, N.3
-
115
-
-
20844432900
-
Gene transfer to human joints: Progress toward a gene therapy of arthritis
-
Evans CH, Robbins PD, Ghivizzani SC, et al. Gene transfer to human joints: progress toward a gene therapy of arthritis. Proc Natl Acad Sci USA 102: 8698-8703 (2005).
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 8698-8703
-
-
Evans, C.H.1
Robbins, P.D.2
Ghivizzani, S.C.3
-
116
-
-
34548816194
-
Gene therapy might not have caused patient's death
-
Wadman M. Gene therapy might not have caused patient's death. Nature 449: 270 (2007).
-
(2007)
Nature
, vol.449
, pp. 270
-
-
Wadman, M.1
-
117
-
-
34548045718
-
Clinical research. Death prompts a review of gene therapy vector
-
Kaiser J. Clinical research. Death prompts a review of gene therapy vector. Science 317: 580 (2007).
-
(2007)
Science
, vol.317
, pp. 580
-
-
Kaiser, J.1
-
118
-
-
34948876831
-
Therapy on trial
-
Hughes V. Therapy on trial. Nat Med 13: 1008-1009 (2007).
-
(2007)
Nat Med
, vol.13
, pp. 1008-1009
-
-
Hughes, V.1
-
119
-
-
34648822160
-
Gene therapy. Questions remain on cause of death in arthritis trial
-
Kaiser J. Gene therapy. Questions remain on cause of death in arthritis trial. Science 317: 1665 (2007).
-
(2007)
Science
, vol.317
, pp. 1665
-
-
Kaiser, J.1
|