In vivo anti-inflammatory and analgesic activities of a purified saponin fraction derived from the root of Ilex pubescens

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 4, 2008, Pages 643-650

  Wang, Jing Rong ^a   Zhou, Hua ^a   Jiang, Zhi Hong ^a   Wong, Yuen Fan ^a   Liu, Liang ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

Analgesic activity; Anti inflammatory activity; Cyclooxygenase; Cytokine; Ilex pubescens; Saponin

Indexed keywords

ACETIC ACID; CARRAGEENAN; CYCLOOXYGENASE 2; HISTAMINE; INTERLEUKIN 10; INTERLEUKIN 4; PLANT EXTRACT; SAPONIN DERIVATIVE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE MODEL; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ILEX; ILEX PUBESCENS; INFLAMMATION; MALE; MOUSE; NOCICEPTIVE STIMULATION; NONHUMAN; PAIN; PAW EDEMA; PLANT ROOT; PROTEIN EXPRESSION; RAT; TAIL FLICK TEST; WRITHING TEST;

ACETIC ACID; ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOTTING, WESTERN; CARRAGEENAN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; FOOT; HEAT; HISTAMINE ANTAGONISTS; ILEX; MALE; MICE; MICE, INBRED ICR; PAIN MEASUREMENT; PLANT ROOTS; SAPONINS;

EID: 41849151491     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.643     Document Type: Article

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