Two-step synthesis of the bipyrrole precursor of prodigiosins

Tetrahedron Letters

Volumn 47, Issue 15, 2006, Pages 2605-2606

  Dairi, Kenza ^a   Tripathy, Sasmita ^a   Attardo, Giorgio ^a   Lavallée, Jean François ^a  

^a INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

Bipyrrole; Haloformylation; Natural product; Prodigiosins; Suzuki coupling; Tambjamines

Indexed keywords

4 METHOXY 2,2' BIPYRROLE 5 CARBOXALDEHYDE; 4 METHOXY 3 PYRROLIN 2 ONE; PRODIGIOSIN; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; POLYMERIZATION; SYNTHESIS;

EID: 33644898091     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2006.02.035     Document Type: Article

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10. 3): δ (ppm) 1.24-1.37 (6H, m), 3.31-3.46 (2H, q, J = 7.1), 3.76 (3H, s), 4.03-4.18 (2H, q, J = 7.1), 5.58 (1H, s), 6.98 (1H, s). HRMS; m/z: 259.0440 [M+1]. Found: 259.0443.
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13. 6): δ (ppm) 3.82 (3H, s), 6.10 (1H, t, J = 2.9), 6.26 (1H, s), 6.73 (1H, d, J = 2.6), 6.89 (1H, br s), 9.27 (1H, s), 11.13-11.29 (1H, br s), 11.32-11.49 (1H, br s). HRMS; m/z: 191.0815 [M+1]. Found: 191.0807.
14. Produced by MDS Pharma Services, South Bothell WA, USA.
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