Hypoxia-inducible factor-1 and nuclear factor-κB inhibitory meroterpene analogues of bakuchiol, a constituent of the seeds of Psoralea corylifolia

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 8, 2008, Pages 2619-2623

  Wu, Cheng Zhu ^a   Hong, Seong Su ^b   Cai, Xing Fu ^a   Dat, Nguyen Tien ^a   Nan, Ji Xing ^c   Hwang, Bang Yeon ^d   Lee, Jung Joon ^a   Lee, Dongho ^b  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Korea University   (South Korea)

^c BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^d Chungbuk National University   (South Korea)

Author keywords

Fabaceae; Hypoxia inducible factor 1; Meroterpenoids; Nuclear factor B; Psoralea corylifolia

Indexed keywords

12,13 DIHYDRO 12,13 DIHYDROXYBAKUCHIOL; 12,13 DIHYDRO 12,13 EPOXYBAKUCHIOL; ACETYLBAKUCHIOL; BAKUCHIOL; BISBAKUCHIOL A; BISBAKUCHIOL B; BISBAKUCHIOL C; HYPOXIA INDUCIBLE FACTOR 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; O ETHYLBAKUCHIOL; O METHYLBAKUCHIOL; TERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL VIABILITY; DRUG STRUCTURE; FEMALE; HELA CELL; HUMAN; HUMAN CELL; MEDICINAL PLANT; PLANT SEED; PROTON NUCLEAR MAGNETIC RESONANCE; PSORALEA CORYLIFOLIA;

CELL LINE, TUMOR; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; NF-KAPPA B; PHENOLS; PSORALEA; SEEDS; STRUCTURE-ACTIVITY RELATIONSHIP; TERPENES;

CULLEN CORYLIFOLIA; FABACEAE;

EID: 41849092669     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.03.028     Document Type: Article

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