New sesquiterpene dimers from Inula britannica inhibit NF-κB activation and NO and TNF-α production in LPS-stimulated RAW264.7 cells

Planta Medica

Volumn 72, Issue 1, 2006, Pages 40-45

  Jin, Hui Zi ^a,b   Lee, Dongho ^a   Lee, Jeong Hyung ^a   Lee, Kyeong ^a   Hong, Young Soo ^a   Choung, Dong Ho ^a   Kim, Young Ho ^b   Lee, Jung Joon ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chungnam National University   (South Korea)

Author keywords

Compositae; Inula britannica; NF B; NO; Sesquiterpene dimer; TNF

Indexed keywords

1 ACETOXY 6ALPHA HYDROXYERIOLANOLIDE; 1,6ALPHA DIHYDROXYERIOLANOLIDE; ACETIC ACID ETHYL ESTER; DIMER; EUPATOLID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INULA BRITANNICA EXTRACT; INULANOLIDE A; INULANOLIDE B; INULANOLIDE C; INULANOLIDE D; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NORBORNENE DERIVATIVE; PLANT EXTRACT; SESQUITERPENE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOASSAY; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG ISOLATION; DRUG POTENCY; DRUG PROTEIN BINDING; IC 50; IN VITRO STUDY; INULA; INULA BRITANNICA; MOUSE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; REPORTER GENE; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL LINE; INHIBITORY CONCENTRATION 50; INULA; LIPOPOLYSACCHARIDES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR STRUCTURE; NF-KAPPA B; NITRIC OXIDE SYNTHASE; PLANT EXTRACTS; PROTEIN BIOSYNTHESIS; SESQUITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; ASTERACEAE; INULA; INULA BRITANNICA;

EID: 32644432027     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1467-9957.2006.00481.x     Document Type: Article

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