Proteomics-based identification of autoantibody against heat shock protein 70 as a diagnostic marker in esophageal squamous cell carcinoma

Cancer Letters

Volumn 263, Issue 2, 2008, Pages 280-290

  Fujita, Yoshihisa ^a   Nakanishi, Toyofumi ^a   Miyamoto, Yoshiharu ^a   Hiramatsu, Masako ^a   Mabuchi, Hideaki ^a   Miyamoto, Akiko ^a   Shimizu, Akira ^a   Takubo, Takayuki ^a   Tanigawa, Nobuhiko ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Autoantibody; Esophageal cancer; Heat shock protein 70; Matrix assisted laser desorption ionization time of flight mass spectrometry; Proteomics

Indexed keywords

AUTOANTIBODY; HEAT SHOCK PROTEIN 70; TUMOR ANTIGEN;

ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ARTICLE; CANCER DIAGNOSIS; COLON CANCER; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEOMICS; STOMACH CANCER; WESTERN BLOTTING;

ADULT; AGED; ANTIBODIES, NEOPLASM; ANTIGENS, NEOPLASM; AUTOANTIBODIES; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; ESOPHAGEAL NEOPLASMS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MIDDLE AGED; PROTEOMICS; TUMOR MARKERS, BIOLOGICAL;

EID: 41649107031     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.01.013     Document Type: Article

References (55)

1. Hanash S. Disease proteomics. Nature 422 (2003) 226-232
2. Honda K., Hayashida Y., Umaki T., Okusaka T., Kosuge T., Kikuchi S., et al. Possible detection of pancreatic cancer by plasma protein profiling. Cancer Res. 65 (2005) 10613-10622
3. Zhang Z., Bast Jr. R.C., Yu Y., Li J., Sokoll L.J., Rai A.J., et al. Three biomarkers identified from serum proteomic analysis for the detection of early stage ovarian cancer. Cancer Res. 64 (2004) 5882-5890
4. Petricoin E.F., Ardekani A.M., Hitt B.A., Levine P.J., Fusaro V.A., Steinberg S.M., et al. Use of proteomic patterns in serum to identify ovarian cancer. Lancet 359 (2002) 572-577
5. Davis M.A., and Hanash S. High-throughput genomic technology in research and clinical management of breast cancer. Plasma-based proteomics in early detection and therapy. Breast Cancer Res. 8 (2006) 217
6. Diamandis E.P. Serum proteomic profiling by matrix-assisted laser desorption-ionization time-of-flight mass spectrometry for cancer diagnosis: next steps. Cancer Res. 66 (2006) 5540-5541
7. Brichory F.M., Misek D.E., Yim A.M., Krause M.C., Giordano T.J., Beer D.G., et al. An immune response manifested by the common occurrence of annexins I and II autoantibodies and high circulating levels of IL-6 in lung cancer. Proc. Natl. Acad. Sci. USA 98 (2001) 9824-9829
8. Le Naour F., Misek D.E., Krause M.C., Deneux L., Giordano T.J., Scholl S., et al. Proteomics-based identification of RS/DJ-1 as a novel circulating tumor antigen in breast cancer. Clin. Cancer Res. 7 (2001) 3328-3335
9. Hong S.H., Misek D.E., Wang H., Puravs E., Giordano T.J., Greenson J.K., et al. An autoantibody-mediated immune response to calreticulin isoforms in pancreatic cancer. Cancer Res. 64 (2004) 5504-5510
10. Brichory F., Beer D., Le Naour F., Giordano T., and Hanash S. Proteomics-based identification of protein gene product 9.5 as a tumor antigen that induces a humoral immune response in lung cancer. Cancer Res. 61 (2001) 7908-7912
11. Imafuku Y., Omenn G.S., and Hanash S. Proteomics approaches to identify tumor antigen directed autoantibodies as cancer biomarkers. Dis. Markers 20 (2004) 149-153
12. Hatakeyama H., Kondo T., Fujii K., Nakanishi Y., Kato H., Fukuda S., et al. Protein clusters associated with carcinogenesis, histological differentiation and nodal metastasis in esophageal cancer. Proteomics 6 (2006) 6300-6316
13. Nishimori T., Tomonaga T., Matsushita K., Oh-Ishi M., Kodera Y., Maeda T., et al. Proteomic analysis of primary esophageal squamous cell carcinoma reveals downregulation of a cell adhesion protein, periplakin. Proteomics 6 (2006) 1011-1018
14. An J.Y., Fan Z.M., Zhuang Z.H., Qin Y.R., Gao S.S., Li J.L., et al. Proteomic analysis of blood level of proteins before and after operation in patients with esophageal squamous cell carcinoma at high-incidence area in Henan Province. World J. Gastroenterol. 10 (2004) 3365-3368
15. Zhang L.Y., Ying W.T., Mao Y.S., He H.Z., Liu Y., Wang H.X., et al. Loss of clusterin both in serum and tissue correlates with the tumorigenesis of esophageal squamous cell carcinoma via proteomics approaches. World J. Gastroenterol. 9 (2003) 650-654
16. A. Jemal, R. Siegel, E. Ward, T. Murray, J. Xu, M.J. Thun, Cancer statistics, 2007. CA Cancer J. Clin. 57 (2007) 43-66.
17. Registration Committee for Esophageal Cancer, in: Comprehensive Registry of Esophageal Cancer in Japan (1998, 1999) and Long-Term Results of Esophagectomy for Esophageal Cancer in Japan (1988-1997), third ed., Japanese Society for Esophageal Diseases, Tokyo, 2002.
18. Enzinger P.C., and Mayer R.J. Esophageal cancer. N. Engl. J. Med. 349 (2003) 2241-2252
19. Shimada H., Nabeya Y., Okazumi S., Matsubara H., Miyazawa Y., Shiratori T., et al. Prognostic significance of CYFRA 21-1 in patients with esophageal squamous cell carcinoma. J. Am. Coll. Surg. 196 (2003) 573-578
20. Shimada H., Nabeya Y., Okazumi S., Matsubara H., Shiratori T., Gunji Y., et al. Prediction of survival with squamous cell carcinoma antigen in patients with resectable esophageal squamous cell carcinoma. Surgery 133 (2003) 486-494
21. Fujita Y., Nakanishi T., Hiramatsu M., Mabuchi H., Miyamoto Y., Miyamoto A., et al. Proteomics-based approach identifying autoantibody against peroxiredoxin VI as a novel serum marker in esophageal squamous cell carcinoma. Clin. Cancer Res. 12 (2006) 6415-6420
22. Nakanishi T., Takeuchi T., Ueda K., Murao H., and Shimizu A. Detection of eight antibodies in cancer patients' sera against proteins derived from the adenocarcinoma A549 cell line using proteomics-based analysis. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 838 (2006) 15-20
23. Nakanishi T., Koyama R., Ikeda T., and Shimizu A. Catalogue of soluble proteins in the human vitreous humor: comparison between diabetic retinopathy and macular hole. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 776 (2002) 89-100
24. Kawasaki H., Toyoda M., Shinohara H., Okuda J., Watanabe I., Yamamoto T., et al. Expression of survivin correlates with apoptosis, proliferation, and angiogenesis during human colorectal tumorigenesis. Cancer 91 (2001) 2026-2032
25. Mosser D.D., and Morimoto R.I. Molecular chaperones and the stress of oncogenesis. Oncogene 23 (2004) 2907-2918
26. Noessner E., Gastpar R., Milani V., Brandl A., Hutzler P.J., Kuppner M.C., et al. Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells. J. Immunol. 169 (2002) 5424-5432
27. Lindquist S., and Craig E.A. The heat-shock proteins. Annu. Rev. Genet. 22 (1988) 631-677
28. Morimoto R.I. Cells in stress: transcriptional activation of heat shock genes. Science 259 (1993) 1409-1410
29. Deocaris C.C., Kaul S.C., and Wadhwa R. On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60. Cell Stress Chaperones 11 (2006) 116-128
30. Beckmann R.P., Mizzen L.E., and Welch W.J. Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assembly. Science 248 (1990) 850-854
31. Meriin A.B., Yaglom J.A., Gabai V.L., Zon L., Ganiatsas S., Mosser D.D., et al. Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: a novel pathway controlled by HSP72. Mol. Cell Biol. 19 (1999) 2547-2555
32. Beere H.M., Wolf B.B., Cain K., Mosser D.D., Mahboubi A., Kuwana T., et al. Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome. Nat. Cell Biol. 2 (2000) 469-475
33. Gabai V.L., Meriin A.B., Mosser D.D., Caron A.W., Rits S., Shifrin V.I., et al. Hsp70 prevents activation of stress kinases. A novel pathway of cellular thermotolerance. J. Biol. Chem. 272 (1997) 18033-18037
34. Yaglom J.A., Gabai V.L., and Sherman M.Y. High levels of heat shock protein Hsp72 in cancer cells suppress default senescence pathways. Cancer Res. 67 (2007) 2373-2381
35. Wang X.P., Liu G.Z., Song A.L., Chen R.F., Li H.Y., and Liu Y. Expression and significance of heat shock protein 70 and glucose-regulated protein 94 in human esophageal carcinoma. World J. Gastroenterol. 11 (2005) 429-432
36. Jazii F.R., Najafi Z., Malekzadeh R., Conrads T.P., Ziaee A.A., Abnet C., et al. Identification of squamous cell carcinoma associated proteins by proteomics and loss of beta tropomyosin expression in esophageal cancer. World J. Gastroenterol. 12 (2006) 7104-7112
37. Miyazaki T., Kato H., Faried A., Sohda M., Nakajima M., Fukai Y., et al. Predictors of response to chemo-radiotherapy and radiotherapy for esophageal squamous cell carcinoma. Anticancer Res. 25 (2005) 2749-2755
38. Ciocca D.R., Clark G.M., Tandon A.K., Fuqua S.A., Welch W.J., and McGuire W.L. Heat shock protein hsp70 in patients with axillary lymph node-negative breast cancer: prognostic implications. J. Natl. Cancer Inst. 85 (1993) 570-574
39. Nanbu K., Konishi I., Komatsu T., Mandai M., Yamamoto S., Kuroda H., et al. Expression of heat shock proteins HSP70 and HSP90 in endometrial carcinomas. Correlation with clinicopathology, sex steroid receptor status, and p53 protein expression. Cancer 77 (1996) 330-338
40. Piura B., Rabinovich A., Yavelsky V., and Wolfson M. Heat shock proteins and malignancies of the female genital tract. Harefuah 141 (2002) 969-972 1010, 1009
41. Syrigos K.N., Harrington K.J., Karayiannakis A.J., Sekara E., Chatziyianni E., Syrigou E.I., et al. Clinical significance of heat shock protein-70 expression in bladder cancer. Urology 61 (2003) 677-680
42. Nakajima M., Kuwano H., Miyazaki T., Masuda N., and Kato H. Significant correlation between expression of heat shock proteins 27, 70 and lymphocyte infiltration in esophageal squamous cell carcinoma. Cancer Lett. 178 (2002) 99-106
43. Kawanishi K., Shiozaki H., Doki Y., Sakita I., Inoue M., Yano M., et al. Prognostic significance of heat shock proteins 27 and 70 in patients with squamous cell carcinoma of the esophagus. Cancer 85 (1999) 1649-1657
44. Takashima M., Kuramitsu Y., Yokoyama Y., Iizuka N., Harada T., Fujimoto M., et al. Proteomic analysis of autoantibodies in patients with hepatocellular carcinoma. Proteomics 6 (2006) 3894-3900
45. Korneeva I., Bongiovanni A.M., Girotra M., Caputo T.A., and Witkin S.S. IgA antibodies to the 27-kDa heat-shock protein in the genital tracts of women with gynecologic cancers. Int. J. Cancer 87 (2000) 824-828
46. Canelle L., Bousquet J., Pionneau C., Deneux L., Imam-Sghiouar N., Caron M., et al. An efficient proteomics-based approach for the screening of autoantibodies. J. Immunol. Methods 299 (2005) 77-89
47. Conroy S.E., Sasieni P.D., Amin V., Wang D.Y., Smith P., Fentiman I.S., et al. Antibodies to heat-shock protein 27 are associated with improved survival in patients with breast cancer. Br. J. Cancer 77 (1998) 1875-1879
48. Trieb K., Gerth R., Windhager R., Grohs J.G., Holzer G., Berger P., et al. Serum antibodies against the heat shock protein 60 are elevated in patients with osteosarcoma. Immunobiology 201 (2000) 368-376
49. Herz I., Rosso R., Roth A., Keren G., and George J. Serum levels of anti heat shock protein 70 antibodies in patients with stable and unstable angina pectoris. Acute Card Care 8 (2006) 46-50
50. Yeom K., Gray J., Nair T.S., Arts H.A., Telian S.A., Disher M.J., et al. Antibodies to HSP-70 in normal donors and autoimmune hearing loss patients. Laryngoscope 113 (2003) 1770-1776
51. Le Naour F., Brichory F., Misek D.E., Brechot C., Hanash S.M., and Beretta L. A distinct repertoire of autoantibodies in hepatocellular carcinoma identified by proteomic analysis. Mol. Cell Proteomics 1 (2002) 197-203
52. Multhoff G., Botzler C., Wiesnet M., Muller E., Meier T., Wilmanns W., et al. A stress-inducible 72-kDa heat-shock protein (HSP72) is expressed on the surface of human tumor cells, but not on normal cells. Int. J. Cancer 61 (1995) 272-279
53. Botzler C., Issels R., and Multhoff G. Heat-shock protein 72 cell-surface expression on human lung carcinoma cells in associated with an increased sensitivity to lysis mediated by adherent natural killer cells. Cancer Immunol. Immunother. 43 (1996) 226-230
54. Multhoff G., Botzler C., Jennen L., Schmidt J., Ellwart J., and Issels R. Heat shock protein 72 on tumor cells: a recognition structure for natural killer cells. J. Immunol. 158 (1997) 4341-4350
55. Gonzalez-Gronow M., Cuchacovich M., Llanos C., Urzua C., Gawdi G., and Pizzo S.V. Prostate cancer cell proliferation in vitro is modulated by antibodies against glucose-regulated protein 78 isolated from patient serum. Cancer Res. 66 (2006) 11424-11431