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Volumn 97, Issue 5, 2008, Pages 416-422

Expression of P53, P27 and KI-67 in colorectal cancer patients of various ethnic origins: Clinical and tissue microarray based analysis

Author keywords

Colorectal neoplasms; Ki 67; Microarray; p21; p53

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1B; KI 67 ANTIGEN; PARAFFIN; PROTEIN P27;

EID: 41549166159     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.20989     Document Type: Article
Times cited : (10)

References (50)
  • 2
    • 0041830469 scopus 로고    scopus 로고
    • Annual report to the nation on the status of cancer, 1975-2000, featuring the uses of surveillance data for cancer prevention and control
    • Weir HK, Thun MJ, Hankey BF, et al.: Annual report to the nation on the status of cancer, 1975-2000, featuring the uses of surveillance data for cancer prevention and control. J Natl Cancer Inst 2003;95:1276-1299.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1276-1299
    • Weir, H.K.1    Thun, M.J.2    Hankey, B.F.3
  • 3
    • 8544246460 scopus 로고    scopus 로고
    • Trends in colorectal cancer incidence and mortality in the Israeli Jewish ethnic populations
    • Barchana M, Liphshitz I, Rozen P: Trends in colorectal cancer incidence and mortality in the Israeli Jewish ethnic populations. Fam Cancer 2004;3:207-214.
    • (2004) Fam Cancer , vol.3 , pp. 207-214
    • Barchana, M.1    Liphshitz, I.2    Rozen, P.3
  • 4
    • 18844464796 scopus 로고    scopus 로고
    • Colorectal carcinoma survival among hereditary nonpolyposis colorectal carcinoma family members
    • Watson P, Lin KM, Rodriguez-Bigas MA, et al.: Colorectal carcinoma survival among hereditary nonpolyposis colorectal carcinoma family members. Cancer 1998;83:259-266.
    • (1998) Cancer , vol.83 , pp. 259-266
    • Watson, P.1    Lin, K.M.2    Rodriguez-Bigas, M.A.3
  • 5
    • 28544446428 scopus 로고    scopus 로고
    • Microsatellite instability and colorectal cancer prognosis
    • Benatti P, Gafa R, Barana D, et al.: Microsatellite instability and colorectal cancer prognosis. Clin Cancer Res 2005;11:8332-8340.
    • (2005) Clin Cancer Res , vol.11 , pp. 8332-8340
    • Benatti, P.1    Gafa, R.2    Barana, D.3
  • 6
    • 0029644482 scopus 로고
    • Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. International Multicentre Pooled Analysis of Colon Cancer Trials (IMPACT) investigators
    • Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. International Multicentre Pooled Analysis of Colon Cancer Trials (IMPACT) investigators. Lancet 1995;345:939-944.
    • (1995) Lancet , vol.345 , pp. 939-944
  • 7
    • 2542615200 scopus 로고    scopus 로고
    • Multicenter International Study of Oxaliplatin/5-Fluorouracil/Leucovorin in the Adjuvant Treatment of Colon Cancer (MOSAIC) Investigators. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer
    • Andre T, Boni C, Mounedji-Boudiaf L, et al.: Multicenter International Study of Oxaliplatin/5-Fluorouracil/Leucovorin in the Adjuvant Treatment of Colon Cancer (MOSAIC) Investigators. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med 2004;350:2343-2351.
    • (2004) N Engl J Med , vol.350 , pp. 2343-2351
    • Andre, T.1    Boni, C.2    Mounedji-Boudiaf, L.3
  • 8
    • 0023748414 scopus 로고
    • Genetic alterations during colorectal-tumour development
    • Vogelstein B, Fearon ER, Hamilton SR, et al.: Genetic alterations during colorectal-tumour development. N Engl J Med 1988;319: 525-532.
    • (1988) N Engl J Med , vol.319 , pp. 525-532
    • Vogelstein, B.1    Fearon, E.R.2    Hamilton, S.R.3
  • 9
    • 0025040233 scopus 로고
    • Suppression of human colorectal carcinoma cell growth by wild-type p53
    • Baker SJ, Markowitz S, Fearon ER, et al.: Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 1990; 249:912-915.
    • (1990) Science , vol.249 , pp. 912-915
    • Baker, S.J.1    Markowitz, S.2    Fearon, E.R.3
  • 10
    • 0027319521 scopus 로고
    • p53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe SW, Schmitt EM, Smith SW, et al.: p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 1993; 362:847-849.
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3
  • 12
    • 0028978774 scopus 로고
    • p53 gene mutations, p53 protein accumulation and compartmentalization in colorectal adenocarcinoma
    • Bosari S, Viale G, Roncalli M, et al.: p53 gene mutations, p53 protein accumulation and compartmentalization in colorectal adenocarcinoma. Am J Pathol 1995;147:790-798.
    • (1995) Am J Pathol , vol.147 , pp. 790-798
    • Bosari, S.1    Viale, G.2    Roncalli, M.3
  • 13
    • 0030753698 scopus 로고    scopus 로고
    • p53 alterations are associated with improved prognosis in distal colonic carcinomas
    • Soong R, Grieu F, Robbins P, et al.: p53 alterations are associated with improved prognosis in distal colonic carcinomas. Clin Cancer Res 1997;3:1405-1411.
    • (1997) Clin Cancer Res , vol.3 , pp. 1405-1411
    • Soong, R.1    Grieu, F.2    Robbins, P.3
  • 14
    • 0032521205 scopus 로고    scopus 로고
    • Ki-ras mutation and p53 overexpression predict the clinical behavior of colorectal cancer: A Southwest Oncology Group study
    • Ahnen DJ, Feigl P, Quan G, et al.: Ki-ras mutation and p53 overexpression predict the clinical behavior of colorectal cancer: A Southwest Oncology Group study. Cancer Res 1998;58:1149-1158.
    • (1998) Cancer Res , vol.58 , pp. 1149-1158
    • Ahnen, D.J.1    Feigl, P.2    Quan, G.3
  • 15
    • 0033015211 scopus 로고    scopus 로고
    • Prognostic value of p53 genetic changes in colorectal cancer
    • Kressner U, Inganas M, Byding S, et al.: Prognostic value of p53 genetic changes in colorectal cancer. J Clin Oncol 1999;17:593-599.
    • (1999) J Clin Oncol , vol.17 , pp. 593-599
    • Kressner, U.1    Inganas, M.2    Byding, S.3
  • 16
    • 0029738119 scopus 로고    scopus 로고
    • p53 nuclear protein overexpression in colorectal cancer: A dominant predictor of survival in patients with advanced hepatic metastases
    • Belluco C, Guillem JG, Kemeny N, et al.: p53 nuclear protein overexpression in colorectal cancer: A dominant predictor of survival in patients with advanced hepatic metastases. J Clin Oncol 1996;14:2696-2701.
    • (1996) J Clin Oncol , vol.14 , pp. 2696-2701
    • Belluco, C.1    Guillem, J.G.2    Kemeny, N.3
  • 17
    • 0030443473 scopus 로고    scopus 로고
    • Prognostic significance of p53 abnormalities in colorectal carcinoma detected by PCR-SSCP and immunohistochemical analysis
    • Leahy DT, Salman R, Mulcahy H, et al.: Prognostic significance of p53 abnormalities in colorectal carcinoma detected by PCR-SSCP and immunohistochemical analysis. J Pathol 1996;180:364-370.
    • (1996) J Pathol , vol.180 , pp. 364-370
    • Leahy, D.T.1    Salman, R.2    Mulcahy, H.3
  • 18
    • 0033975032 scopus 로고    scopus 로고
    • Thymidilate synthase and p53 primary tumour expression as predictive factors for advanced colorectal cancer patients
    • Paradiso A, Simone G, Petroni S, et al.: Thymidilate synthase and p53 primary tumour expression as predictive factors for advanced colorectal cancer patients. Br J Cancer 2000;82:560-567.
    • (2000) Br J Cancer , vol.82 , pp. 560-567
    • Paradiso, A.1    Simone, G.2    Petroni, S.3
  • 19
    • 0036605096 scopus 로고    scopus 로고
    • Prognostic significance of p53 mutations in colon cancer at the population level
    • Samowitz WS, Curtin K, Ma KN, et al.: Prognostic significance of p53 mutations in colon cancer at the population level. Int J Cancer 2002;99:597-602.
    • (2002) Int J Cancer , vol.99 , pp. 597-602
    • Samowitz, W.S.1    Curtin, K.2    Ma, K.N.3
  • 20
    • 0033815352 scopus 로고    scopus 로고
    • Prognostic significance of TP53 gene mutation in 995 cases of colorectal carcinoma. Influence of tumour site, stage, adjuvant chemotherapy and type of mutation
    • Soong R, Powell B, Elsaleh H, et al.: Prognostic significance of TP53 gene mutation in 995 cases of colorectal carcinoma. Influence of tumour site, stage, adjuvant chemotherapy and type of mutation. Eur J Cancer 2000;36:2053-2060.
    • (2000) Eur J Cancer , vol.36 , pp. 2053-2060
    • Soong, R.1    Powell, B.2    Elsaleh, H.3
  • 21
    • 0027285380 scopus 로고
    • p53 mutations increase resistance to ionizing radiation
    • Lee JM, Bernstein A: p53 mutations increase resistance to ionizing radiation. Proc Natl Acad Sci USA 1993;90:5742-5746.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5742-5746
    • Lee, J.M.1    Bernstein, A.2
  • 22
    • 0029962567 scopus 로고    scopus 로고
    • Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells
    • Yang B, Eshleman JR, Berger NA, et al.: Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells. Clin Cancer Res 1996;2:1649-1657.
    • (1996) Clin Cancer Res , vol.2 , pp. 1649-1657
    • Yang, B.1    Eshleman, J.R.2    Berger, N.A.3
  • 23
    • 0028363519 scopus 로고
    • p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
    • Toyoshima H, Hunter T: p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 1994;78:67-74.
    • (1994) Cell , vol.78 , pp. 67-74
    • Toyoshima, H.1    Hunter, T.2
  • 24
    • 0029024015 scopus 로고
    • Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
    • Pagano M, Tam SW, Theodoras AM, et al.: Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 1995;269:682-685.
    • (1995) Science , vol.269 , pp. 682-685
    • Pagano, M.1    Tam, S.W.2    Theodoras, A.M.3
  • 25
    • 0029670477 scopus 로고    scopus 로고
    • Translational control of p27Kip1 accumulation during the cell cycle
    • Hengst L, Reed SI: Translational control of p27Kip1 accumulation during the cell cycle. Science 1996;271:1861-1864.
    • (1996) Science , vol.271 , pp. 1861-1864
    • Hengst, L.1    Reed, S.I.2
  • 26
    • 0031439355 scopus 로고    scopus 로고
    • Promoting apoptosis: A novel activity associated with the cyclin-dependent kinase inhibitor p27
    • Katayose Y, Kim M, Rakkar AN, et al.: Promoting apoptosis: A novel activity associated with the cyclin-dependent kinase inhibitor p27. Cancer Res 1997;57:5441-5445.
    • (1997) Cancer Res , vol.57 , pp. 5441-5445
    • Katayose, Y.1    Kim, M.2    Rakkar, A.N.3
  • 27
    • 0030947356 scopus 로고    scopus 로고
    • High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: Inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers
    • Fredersdorf S, Burns J, Milne AM, et al.: High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: Inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers. Proc Natl Acad Sci USA 1997;94:6380-6385.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6380-6385
    • Fredersdorf, S.1    Burns, J.2    Milne, A.M.3
  • 28
    • 2542454710 scopus 로고    scopus 로고
    • Determination of molecular marker expression can predict clinical outcome in colon carcinomas
    • Galizia G, Lieto E, Ferraraccio F, et al.: Determination of molecular marker expression can predict clinical outcome in colon carcinomas. Clin Cancer Res 2004;10:3490-3499.
    • (2004) Clin Cancer Res , vol.10 , pp. 3490-3499
    • Galizia, G.1    Lieto, E.2    Ferraraccio, F.3
  • 29
    • 0031048236 scopus 로고    scopus 로고
    • Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
    • Loda M, Cukor B, Tam SW, et al.: Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat Med 1997;3:231-234.
    • (1997) Nat Med , vol.3 , pp. 231-234
    • Loda, M.1    Cukor, B.2    Tam, S.W.3
  • 30
    • 0007809476 scopus 로고    scopus 로고
    • p27 cell-cycle inhibitor is inversely correlated with lymph node metastases in right-sided colon cancer
    • Liu DF, Ferguson K, Cooper GS, et al.: p27 cell-cycle inhibitor is inversely correlated with lymph node metastases in right-sided colon cancer. J Clin Lab Anal 1999;13:291-295.
    • (1999) J Clin Lab Anal , vol.13 , pp. 291-295
    • Liu, D.F.1    Ferguson, K.2    Cooper, G.S.3
  • 31
    • 0020694123 scopus 로고
    • Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation
    • Gerdes J, Schwab U, Lemke H, et al.: Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int J Cancer 1983;3:13-20.
    • (1983) Int J Cancer , vol.3 , pp. 13-20
    • Gerdes, J.1    Schwab, U.2    Lemke, H.3
  • 32
    • 0021212003 scopus 로고
    • Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67
    • Gerdes J, Lemke H, Baisch H, et al.: Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 1984;133:1710-1715.
    • (1984) J Immunol , vol.133 , pp. 1710-1715
    • Gerdes, J.1    Lemke, H.2    Baisch, H.3
  • 33
    • 0024369033 scopus 로고
    • Ki67 immunostaining in primary breast cancer: Pathological and clinical associations
    • Bouzubar N, Walker KJ, Griffiths K, et al.: Ki67 immunostaining in primary breast cancer: Pathological and clinical associations. Br J Cancer 1989;59:943-947.
    • (1989) Br J Cancer , vol.59 , pp. 943-947
    • Bouzubar, N.1    Walker, K.J.2    Griffiths, K.3
  • 34
    • 0036534002 scopus 로고    scopus 로고
    • Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer
    • Allegra CJ, Parr AL, Wold LE, et al.: Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer. J Clin Oncol 2002;20:1735-1743.
    • (2002) J Clin Oncol , vol.20 , pp. 1735-1743
    • Allegra, C.J.1    Parr, A.L.2    Wold, L.E.3
  • 35
    • 0024333345 scopus 로고
    • Immunohistochemical analysis of cell kinetic parameters in colonic adenocarcinomas, adenomas, and normal mucosa
    • Johnston PG, O'Brien MJ, Dervan PA, et al.: Immunohistochemical analysis of cell kinetic parameters in colonic adenocarcinomas, adenomas, and normal mucosa. Hum Pathol 1989;20:696-700.
    • (1989) Hum Pathol , vol.20 , pp. 696-700
    • Johnston, P.G.1    O'Brien, M.J.2    Dervan, P.A.3
  • 36
    • 0030895155 scopus 로고    scopus 로고
    • Determination of proliferative activity in colorectal carcinoma using monoclonal antibody Ki67
    • Kyzer S, Gordon PH: Determination of proliferative activity in colorectal carcinoma using monoclonal antibody Ki67. Dis Colon Rectum 1997;40:322-325.
    • (1997) Dis Colon Rectum , vol.40 , pp. 322-325
    • Kyzer, S.1    Gordon, P.H.2
  • 37
    • 23844534811 scopus 로고    scopus 로고
    • Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics. Reporting recommendations for tumour marker prognostic studies (REMARK)
    • McShane LM, Altman DG, Sauerbrei W, et al.: Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics. Reporting recommendations for tumour marker prognostic studies (REMARK). J Natl Cancer Inst 2005;97: 1180-1184.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1180-1184
    • McShane, L.M.1    Altman, D.G.2    Sauerbrei, W.3
  • 38
    • 0034769529 scopus 로고    scopus 로고
    • Tissue microarray profiling of cancer specimens and cell lines: Opportunities and limitations
    • Hoos A, Cordon-Cardo C: Tissue microarray profiling of cancer specimens and cell lines: Opportunities and limitations. Lab Invest 2001;81:1331-1338.
    • (2001) Lab Invest , vol.81 , pp. 1331-1338
    • Hoos, A.1    Cordon-Cardo, C.2
  • 39
    • 0031822837 scopus 로고    scopus 로고
    • Tissue microarrays for high-throughput molecular profiling of tumour specimens
    • Kononen J, Bubendorf L, Kallioniemi A, et al.: Tissue microarrays for high-throughput molecular profiling of tumour specimens. Nat Med 1998;4:844-847.
    • (1998) Nat Med , vol.4 , pp. 844-847
    • Kononen, J.1    Bubendorf, L.2    Kallioniemi, A.3
  • 40
    • 0141656847 scopus 로고    scopus 로고
    • Prognostic factors in colorectal cancer. College of American Pathologists Consensus Statement 1999
    • Compton CC, Fielding LP, Burgart LJ, et al.: Prognostic factors in colorectal cancer. College of American Pathologists Consensus Statement 1999. Arch Pathol Lab Med 2000;124:979-994.
    • (2000) Arch Pathol Lab Med , vol.124 , pp. 979-994
    • Compton, C.C.1    Fielding, L.P.2    Burgart, L.J.3
  • 41
    • 0141455146 scopus 로고    scopus 로고
    • Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA_expression levels: Predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracil
    • Kornmann M, Schwabe W, Sander S, et al.: Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA_expression levels: Predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracil. Clin Cancer Res 2003;9:4116-4124.
    • (2003) Clin Cancer Res , vol.9 , pp. 4116-4124
    • Kornmann, M.1    Schwabe, W.2    Sander, S.3
  • 42
    • 21344471434 scopus 로고    scopus 로고
    • Genetic analyses in consecutive israeli jewish colorectal cancer patients
    • Fidder HH, Figer A, Geva R, et al.: Genetic analyses in consecutive israeli jewish colorectal cancer patients. Am J Gastroenterol 2005;100:1376-1380.
    • (2005) Am J Gastroenterol , vol.100 , pp. 1376-1380
    • Fidder, H.H.1    Figer, A.2    Geva, R.3
  • 43
    • 0022450165 scopus 로고
    • Colorectal adenomatous polyps and carcinoma in Ashkenazi and non-Ashkenazi Jews in Israel
    • Bat L, Pines A, Ron E, et al.: Colorectal adenomatous polyps and carcinoma in Ashkenazi and non-Ashkenazi Jews in Israel. Cancer 1986;58:1167-1171.
    • (1986) Cancer , vol.58 , pp. 1167-1171
    • Bat, L.1    Pines, A.2    Ron, E.3
  • 45
    • 0035180732 scopus 로고    scopus 로고
    • Tissue microarrays for rapid linking of molecular changes to clinical endpoints
    • Torhorst J, Bucher C, Kononen J, et al.: Tissue microarrays for rapid linking of molecular changes to clinical endpoints. Am J Pathol 2001;159:2249-2256.
    • (2001) Am J Pathol , vol.159 , pp. 2249-2256
    • Torhorst, J.1    Bucher, C.2    Kononen, J.3
  • 46
    • 0034535382 scopus 로고    scopus 로고
    • Validation of tissue microarray technology in breast carcinoma
    • Camp RL, Charette LA, Rimm DL: Validation of tissue microarray technology in breast carcinoma. Lab Invest 2000;80:1943-1949.
    • (2000) Lab Invest , vol.80 , pp. 1943-1949
    • Camp, R.L.1    Charette, L.A.2    Rimm, D.L.3
  • 47
    • 0036897535 scopus 로고    scopus 로고
    • Tissue microarray molecular profiling of early, node-negative adenocarcinoma of the rectum: A comprehensive analysis
    • Hoos A, Nissan A, Stojadinovic A, et al.: Tissue microarray molecular profiling of early, node-negative adenocarcinoma of the rectum: A comprehensive analysis. Clin Cancer Res 2002;8: 3841-3849.
    • (2002) Clin Cancer Res , vol.8 , pp. 3841-3849
    • Hoos, A.1    Nissan, A.2    Stojadinovic, A.3
  • 48
    • 9144231228 scopus 로고    scopus 로고
    • Molecular lesions in colorectal cancer: Impact on prognosis? Original data and review of the literature
    • Klump B, Nehls O, Okech T, et al.: Molecular lesions in colorectal cancer: Impact on prognosis? Original data and review of the literature. Int J Colorectal Dis 2004;19:23-42.
    • (2004) Int J Colorectal Dis , vol.19 , pp. 23-42
    • Klump, B.1    Nehls, O.2    Okech, T.3
  • 49
    • 0031048236 scopus 로고    scopus 로고
    • Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
    • Loda M, Cukor B, Tam SW, et al.: Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat Med 1997;3:231-234.
    • (1997) Nat Med , vol.3 , pp. 231-234
    • Loda, M.1    Cukor, B.2    Tam, S.W.3
  • 50
    • 0033986568 scopus 로고    scopus 로고
    • Prognostic significance of p27(kip1) protein expression and spontaneous apoptosis in patients with colorectal adenocarcinomas
    • Tenjo T, Toyoda M, Okuda J, et al.: Prognostic significance of p27(kip1) protein expression and spontaneous apoptosis in patients with colorectal adenocarcinomas. Oncology 2000;58: 45-51.
    • (2000) Oncology , vol.58 , pp. 45-51
    • Tenjo, T.1    Toyoda, M.2    Okuda, J.3


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