메뉴 건너뛰기




Volumn 2, Issue 10, 2007, Pages

Investigating the role of islet cytoarchitecture in its oscillation using a new β-cell cluster model

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; INSULIN; GLUCOSE;

EID: 41549162873     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000983     Document Type: Article
Times cited : (39)

References (75)
  • 1
    • 0034046772 scopus 로고    scopus 로고
    • Pathophysiology of impaired pulsatile insulin release
    • Bergsten P (2000) Pathophysiology of impaired pulsatile insulin release. Diabetes Metab Res Rev 16: 179-191.
    • (2000) Diabetes Metab Res Rev , vol.16 , pp. 179-191
    • Bergsten, P.1
  • 2
    • 0036311276 scopus 로고    scopus 로고
    • Pulsatile insulin secretion: Detection, regulation, and role in diabetes
    • Porksen N, Hollingdal M, Juhl C, Butler P, Veldhuis JD, et al. (2002) Pulsatile insulin secretion: detection, regulation, and role in diabetes. Diabetes 51 Suppl 1: S245-254.
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 1
    • Porksen, N.1    Hollingdal, M.2    Juhl, C.3    Butler, P.4    Veldhuis, J.D.5
  • 3
    • 0023141872 scopus 로고
    • The insulin receptor concept and its relation to the treatment of diabetes
    • Ward GM (1987) The insulin receptor concept and its relation to the treatment of diabetes. Drugs 33: 156-170.
    • (1987) Drugs , vol.33 , pp. 156-170
    • Ward, G.M.1
  • 4
    • 0020791738 scopus 로고
    • Pulsatile insulin has greater hypoglycemic effect than continuous delivery
    • Matthews DR, Naylor BA, Jones RG, Ward GM, Turner RC (1983) Pulsatile insulin has greater hypoglycemic effect than continuous delivery. Diabetes 32: 617-621.
    • (1983) Diabetes , vol.32 , pp. 617-621
    • Matthews, D.R.1    Naylor, B.A.2    Jones, R.G.3    Ward, G.M.4    Turner, R.C.5
  • 5
    • 0023448602 scopus 로고
    • The pituitary gland secretes in bursts: Appraising the nature of glandular secretory impulses by simultaneous multiple-parameter deconvolution of plasma hormone concentrations
    • Veldhuis JD, Carlson ML, Johnson ML (1987) The pituitary gland secretes in bursts: appraising the nature of glandular secretory impulses by simultaneous multiple-parameter deconvolution of plasma hormone concentrations. Proc Natl Acad Sci U S A 84: 7686-7690.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 7686-7690
    • Veldhuis, J.D.1    Carlson, M.L.2    Johnson, M.L.3
  • 6
    • 0023948792 scopus 로고
    • Pulsatile insulin delivery is more efficient than continuous infusion in modulating islet cell function in normal subjects and patients with type 1 diabetes
    • Paolisso G, Sgambato S, Torella R, Varricchio M, Scheen A, et al. (1988) Pulsatile insulin delivery is more efficient than continuous infusion in modulating islet cell function in normal subjects and patients with type 1 diabetes. J Clin Endocrinol Metab 66: 1220-1226.
    • (1988) J Clin Endocrinol Metab , vol.66 , pp. 1220-1226
    • Paolisso, G.1    Sgambato, S.2    Torella, R.3    Varricchio, M.4    Scheen, A.5
  • 7
    • 0023746609 scopus 로고
    • Advantages of pulsatile administration of human insulin on endogenous pancreatic secretion in the normal subject and in type 1 diabetics]
    • Paolisso G, Sgambato S, Scheen AJ, Torella R, Lefebvre PJ (1988) [Advantages of pulsatile administration of human insulin on endogenous pancreatic secretion in the normal subject and in type 1 diabetics]. Ann Med Interne (Paris) 139: 144-145.
    • (1988) Ann Med Interne (Paris) , vol.139 , pp. 144-145
    • Paolisso, G.1    Sgambato, S.2    Scheen, A.J.3    Torella, R.4    Lefebvre, P.J.5
  • 8
    • 0022497629 scopus 로고
    • Efficacy of pulsatile versus continuous insulin administration on hepatic glucose production and glucose utilization in type I diabetic humans
    • Bratusch-Marrain PR, Komjati M, Waldhausl WK (1986) Efficacy of pulsatile versus continuous insulin administration on hepatic glucose production and glucose utilization in type I diabetic humans. Diabetes 35: 922-926.
    • (1986) Diabetes , vol.35 , pp. 922-926
    • Bratusch-Marrain, P.R.1    Komjati, M.2    Waldhausl, W.K.3
  • 10
    • 0026592372 scopus 로고
    • Loss of regular oscillatory insulin secretion in islet cell antibody positive non-diabetic subjects
    • Bingley PJ, Matthews DR, Williams AJ, Bottazzo GF, Gale EA (1992) Loss of regular oscillatory insulin secretion in islet cell antibody positive non-diabetic subjects. Diabetologia 35: 32-38.
    • (1992) Diabetologia , vol.35 , pp. 32-38
    • Bingley, P.J.1    Matthews, D.R.2    Williams, A.J.3    Bottazzo, G.F.4    Gale, E.A.5
  • 11
    • 0023951171 scopus 로고
    • Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes
    • O'Rahilly S, Turner RC, Matthews DR (1988) Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes. N Engl J Med 318: 1225-1230.
    • (1988) N Engl J Med , vol.318 , pp. 1225-1230
    • O'Rahilly, S.1    Turner, R.C.2    Matthews, D.R.3
  • 12
    • 0030955017 scopus 로고    scopus 로고
    • Disorderly and nonstationary insulin secretion in relatives of patients with NIDDM
    • Schmitz O, Porksen N, Nyholm B, Skjaerback C, Butler PC, et al. (1997) Disorderly and nonstationary insulin secretion in relatives of patients with NIDDM. Am J Physiol 272: E218-226.
    • (1997) Am J Physiol , vol.272
    • Schmitz, O.1    Porksen, N.2    Nyholm, B.3    Skjaerback, C.4    Butler, P.C.5
  • 13
    • 0023791327 scopus 로고
    • Emergence of organized bursting in clusters of pancreatic beta-cells by channel sharing
    • Sherman A, Rinzel J, Keizer J (1988) Emergence of organized bursting in clusters of pancreatic beta-cells by channel sharing. Biophys J 54: 411-425.
    • (1988) Biophys J , vol.54 , pp. 411-425
    • Sherman, A.1    Rinzel, J.2    Keizer, J.3
  • 14
    • 0025979886 scopus 로고
    • Model for synchronization of pancreatic beta-cells by gap junction coupling
    • Sherman A, Rinzel J (1991) Model for synchronization of pancreatic beta-cells by gap junction coupling. Biophys J 59: 547-559.
    • (1991) Biophys J , vol.59 , pp. 547-559
    • Sherman, A.1    Rinzel, J.2
  • 15
    • 0027161335 scopus 로고
    • Why pancreatic islets burst but single beta cells do not. The heterogeneity hypothesis
    • Smolen P, Rinzel J, Sherman A (1993) Why pancreatic islets burst but single beta cells do not. The heterogeneity hypothesis. Biophys J 64: 1668-1680.
    • (1993) Biophys J , vol.64 , pp. 1668-1680
    • Smolen, P.1    Rinzel, J.2    Sherman, A.3
  • 16
    • 0042879951 scopus 로고    scopus 로고
    • Insulin granule dynamics in pancreatic beta cells
    • Rorsman P, Renstrom E (2003) Insulin granule dynamics in pancreatic beta cells. Diabetologia 46: 1029-1045.
    • (2003) Diabetologia , vol.46 , pp. 1029-1045
    • Rorsman, P.1    Renstrom, E.2
  • 17
    • 0033058934 scopus 로고    scopus 로고
    • Modulation of the bursting properties of single mouse pancreatic beta-cells by artificial conductances
    • Kinard TA, de Vries G, Sherman A, Satin LS (1999) Modulation of the bursting properties of single mouse pancreatic beta-cells by artificial conductances. Biophys J 76: 1423-1435.
    • (1999) Biophys J , vol.76 , pp. 1423-1435
    • Kinard, T.A.1    de Vries, G.2    Sherman, A.3    Satin, L.S.4
  • 18
    • 0024386388 scopus 로고
    • Perforated patch recording' allows long-term monitoring of metabolite-induced electrical activity and voltage-dependent Ca2+ currents in pancreatic islet B cells
    • Falke LC, Gillis KD, Pressel DM, Mister S (1989) 'Perforated patch recording' allows long-term monitoring of metabolite-induced electrical activity and voltage-dependent Ca2+ currents in pancreatic islet B cells. FEBS Lett 251: 167-172.
    • (1989) FEBS Lett , vol.251 , pp. 167-172
    • Falke, L.C.1    Gillis, K.D.2    Pressel, D.M.3    Mister, S.4
  • 19
    • 0025054950 scopus 로고
    • Simultaneous recordings of glucose dependent electrical activity and ATP-regulated K(+)-currents in isolated mouse pancreatic beta-cells
    • Smith PA, Ashcroft FM, Rorsman P (1990) Simultaneous recordings of glucose dependent electrical activity and ATP-regulated K(+)-currents in isolated mouse pancreatic beta-cells. FEBS Lett 261: 187-190.
    • (1990) FEBS Lett , vol.261 , pp. 187-190
    • Smith, P.A.1    Ashcroft, F.M.2    Rorsman, P.3
  • 20
    • 0031051021 scopus 로고    scopus 로고
    • Oscillation of gap junction electrical coupling in the mouse pancreatic islets of Langerhans
    • Andreu E, Soria B, Sanchez-Andres JV (1997) Oscillation of gap junction electrical coupling in the mouse pancreatic islets of Langerhans. J Physiol 498(Pt 3): 753-761.
    • (1997) J Physiol , vol.498 , Issue.PART 3 , pp. 753-761
    • Andreu, E.1    Soria, B.2    Sanchez-Andres, J.V.3
  • 21
    • 0029057769 scopus 로고
    • The electrical activity of mouse pancreatic beta-cells recorded in vivo shows glucose-dependent oscillations
    • Sanchez-Andres JV, Gomis A, Valdeolmillos M (1995) The electrical activity of mouse pancreatic beta-cells recorded in vivo shows glucose-dependent oscillations. J Physiol 486(Pt 1): 223-228.
    • (1995) J Physiol , vol.486 , Issue.PART 1 , pp. 223-228
    • Sanchez-Andres, J.V.1    Gomis, A.2    Valdeolmillos, M.3
  • 22
    • 0029940813 scopus 로고    scopus 로고
    • In vivo synchronous membrane potential oscillations in mouse pancreatic beta-cells: Lack of co-ordination between islets
    • Valdeolmillos M, Gomis A, Sanchez-Andres JV (1996) In vivo synchronous membrane potential oscillations in mouse pancreatic beta-cells: lack of co-ordination between islets. J Physiol 493(Pt 1): 9-18.
    • (1996) J Physiol , vol.493 , Issue.PART 1 , pp. 9-18
    • Valdeolmillos, M.1    Gomis, A.2    Sanchez-Andres, J.V.3
  • 23
    • 0033563173 scopus 로고    scopus 로고
    • Homologous and heterologous asynchronicity between identified alpha-, beta- and delta-cells within intact islets of Langerhans in the mouse
    • Nadal A, Quesada I, Soria B (1999) Homologous and heterologous asynchronicity between identified alpha-, beta- and delta-cells within intact islets of Langerhans in the mouse. J Physiol 517(Pt 1): 85-93.
    • (1999) J Physiol , vol.517 , Issue.PART 1 , pp. 85-93
    • Nadal, A.1    Quesada, I.2    Soria, B.3
  • 24
    • 0033231390 scopus 로고    scopus 로고
    • Influence of cell number on the characteristics and synchrony of Ca2+ oscillations in clusters of mouse pancreatic islet cells
    • Jonkers FC, Jonas JC, Gilon P, Henquin JC (1999) Influence of cell number on the characteristics and synchrony of Ca2+ oscillations in clusters of mouse pancreatic islet cells. J Physiol 520 Pt 3: 839-849.
    • (1999) J Physiol , vol.520 , Issue.PART 3 , pp. 839-849
    • Jonkers, F.C.1    Jonas, J.C.2    Gilon, P.3    Henquin, J.C.4
  • 25
    • 0020957719 scopus 로고
    • Minimal model for membrane oscillations in the pancreatic beta-cell
    • Chay TR, Keizer J (1983) Minimal model for membrane oscillations in the pancreatic beta-cell. Biophys J 42: 181-190.
    • (1983) Biophys J , vol.42 , pp. 181-190
    • Chay, T.R.1    Keizer, J.2
  • 26
    • 0023751870 scopus 로고
    • Role of single-channel stochastic noise on bursting dusters of pancreatic beta-cells
    • Chay TR, Kang HS (1988) Role of single-channel stochastic noise on bursting dusters of pancreatic beta-cells. Biophys J 54: 427-435.
    • (1988) Biophys J , vol.54 , pp. 427-435
    • Chay, T.R.1    Kang, H.S.2
  • 27
    • 0029784059 scopus 로고    scopus 로고
    • Contributions of modeling to understanding stimulus-secretion coupling in pancreatic beta-cells
    • Sherman A (1996) Contributions of modeling to understanding stimulus-secretion coupling in pancreatic beta-cells. Am J Physiol 271: E362-372.
    • (1996) Am J Physiol , vol.271
    • Sherman, A.1
  • 29
    • 0034968760 scopus 로고    scopus 로고
    • From spikers to bursters via coupling: Help from heterogeneity
    • de Vries G, Sherman A (2001) From spikers to bursters via coupling: help from heterogeneity. Bull Math Biol 63: 371-391.
    • (2001) Bull Math Biol , vol.63 , pp. 371-391
    • de Vries, G.1    Sherman, A.2
  • 30
    • 3042736858 scopus 로고    scopus 로고
    • Three roads to islet bursting: Emergent oscillations in coupled phantom bursters
    • Zimliki CL, Mears D, Sherman A (2004) Three roads to islet bursting: emergent oscillations in coupled phantom bursters. Biophys J 87: 193-206.
    • (2004) Biophys J , vol.87 , pp. 193-206
    • Zimliki, C.L.1    Mears, D.2    Sherman, A.3
  • 31
    • 23244441271 scopus 로고    scopus 로고
    • Intra- and Inter-islet Synchronization of Metabolically Driven Insulin Secretion
    • Pedersen MG, Bertram M, Sherman A (2005) Intra- and Inter-islet Synchronization of Metabolically Driven Insulin Secretion. Biophysical Journal 89: 107-119.
    • (2005) Biophysical Journal , vol.89 , pp. 107-119
    • Pedersen, M.G.1    Bertram, M.2    Sherman, A.3
  • 32
    • 24144463906 scopus 로고    scopus 로고
    • How noise and coupling induce bursting action potentials in pancreatic {beta}-cells
    • Jo J, Kang H, Choi MY, Koh DS (2005) How noise and coupling induce bursting action potentials in pancreatic {beta}-cells. Biophys J 89: 1534-1542.
    • (2005) Biophys J , vol.89 , pp. 1534-1542
    • Jo, J.1    Kang, H.2    Choi, M.Y.3    Koh, D.S.4
  • 33
    • 42749103603 scopus 로고    scopus 로고
    • Analysis of the noise-induced bursting-spiking transition in a pancreatic beta-cell model
    • Aguirre J, Mosekilde E, Sanjuan MA (2004) Analysis of the noise-induced bursting-spiking transition in a pancreatic beta-cell model. Phys Rev E Stat Nonlin Soft Matter Phys 69: 041910.
    • (2004) Phys Rev E Stat Nonlin Soft Matter Phys , vol.69 , pp. 041910
    • Aguirre, J.1    Mosekilde, E.2    Sanjuan, M.A.3
  • 34
    • 17044393950 scopus 로고    scopus 로고
    • A comment on noise enhanced bursting in pancreatic beta-cells
    • Pedersen MG (2005) A comment on noise enhanced bursting in pancreatic beta-cells. J Theor Biol 235: 1-3.
    • (2005) J Theor Biol , vol.235 , pp. 1-3
    • Pedersen, M.G.1
  • 35
    • 24344459011 scopus 로고    scopus 로고
    • Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy
    • Brissova M, Fowler MJ, Nicholson WE, Chu A, Hirshberg B, et al. (2005) Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy. J Histochem Cytochem 53: 1087-1097.
    • (2005) J Histochem Cytochem , vol.53 , pp. 1087-1097
    • Brissova, M.1    Fowler, M.J.2    Nicholson, W.E.3    Chu, A.4    Hirshberg, B.5
  • 36
    • 33144467088 scopus 로고    scopus 로고
    • The unique cytoarchitecture of human pancreatic islets has implications for islet cell function
    • Cabrera O, Berman DM, Kenyon NS, Ricordi C, Berggren P-O, et al. (2006) The unique cytoarchitecture of human pancreatic islets has implications for islet cell function. Proc Natl Acad Sci U S A 103: 2334-2339.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2334-2339
    • Cabrera, O.1    Berman, D.M.2    Kenyon, N.S.3    Ricordi, C.4    Berggren, P.-O.5
  • 37
    • 0002685120 scopus 로고
    • Electrophysiology of the pancreatic beta-cell
    • Drazin B, Melmed S, LeRoith D, eds, New York: Alan R. Liss
    • Atwater I, Carroll P, Li MX (1989) Electrophysiology of the pancreatic beta-cell. In: Drazin B, Melmed S, LeRoith D, eds. Insulin secretion. New York: Alan R. Liss.
    • (1989) Insulin secretion
    • Atwater, I.1    Carroll, P.2    Li, M.X.3
  • 38
    • 0027994543 scopus 로고
    • Glucose induces oscillatory Ca2+ signalling and insulin release in human pancreatic beta cells
    • Hellman B, Gylfe E, Bergsten P, Grapengiesser E, Lund PE, et al. (1994) Glucose induces oscillatory Ca2+ signalling and insulin release in human pancreatic beta cells. Diabetologia 37 Suppl 2: S11-20.
    • (1994) Diabetologia , vol.37 , Issue.SUPPL. 2
    • Hellman, B.1    Gylfe, E.2    Bergsten, P.3    Grapengiesser, E.4    Lund, P.E.5
  • 40
    • 0029101240 scopus 로고
    • Magnitude and modulation of pancreatic beta-cell gap junction electrical conductance in situ
    • Mears D, Sheppard NF Jr, Atwater I, Rojas E (1995) Magnitude and modulation of pancreatic beta-cell gap junction electrical conductance in situ. J Membr Biol 146: 163-176.
    • (1995) J Membr Biol , vol.146 , pp. 163-176
    • Mears, D.1    Sheppard Jr, N.F.2    Atwater, I.3    Rojas, E.4
  • 41
    • 0026059963 scopus 로고
    • Biophysical properties of gap junctions between freshly dispersed pairs of mouse pancreatic beta cells
    • Perez-Armendariz M, Roy C, Spray DC, Bennett MY (1991) Biophysical properties of gap junctions between freshly dispersed pairs of mouse pancreatic beta cells. Biophys J 59: 76-92.
    • (1991) Biophys J , vol.59 , pp. 76-92
    • Perez-Armendariz, M.1    Roy, C.2    Spray, D.C.3    Bennett, M.Y.4
  • 43
    • 20044389102 scopus 로고    scopus 로고
    • Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release
    • Ravier MA, Guldenagel M, Charollais A, Gjinovci A, Caille D, et al. (2005) Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release. Diabetes 54: 1798-1807.
    • (2005) Diabetes , vol.54 , pp. 1798-1807
    • Ravier, M.A.1    Guldenagel, M.2    Charollais, A.3    Gjinovci, A.4    Caille, D.5
  • 44
    • 0036319123 scopus 로고    scopus 로고
    • Downregulation of connexin 43 expression by high glucose reduces gap junction activity in microvascular endothelial cells
    • Sato T, Haimovici R, Kao R, Li AF, Roy S (2002) Downregulation of connexin 43 expression by high glucose reduces gap junction activity in microvascular endothelial cells. Diabetes 51: 1565-1571.
    • (2002) Diabetes , vol.51 , pp. 1565-1571
    • Sato, T.1    Haimovici, R.2    Kao, R.3    Li, A.F.4    Roy, S.5
  • 46
    • 12344323484 scopus 로고    scopus 로고
    • Type 2 diabetes-a matter of beta-cell life and death?
    • Rhodes CJ (2005) Type 2 diabetes-a matter of beta-cell life and death? Science 307: 380-384.
    • (2005) Science , vol.307 , pp. 380-384
    • Rhodes, C.J.1
  • 48
    • 33244458017 scopus 로고    scopus 로고
    • Critical role of gap junction coupled KATP channel activity for regulated insulin secretion
    • Rocheleau JV, Remedi MS, Granada B, Head WS, Koster JC, et al. (2006) Critical role of gap junction coupled KATP channel activity for regulated insulin secretion. PLoS Biol 4: e26.
    • (2006) PLoS Biol , vol.4
    • Rocheleau, J.V.1    Remedi, M.S.2    Granada, B.3    Head, W.S.4    Koster, J.C.5
  • 49
    • 0141844506 scopus 로고    scopus 로고
    • Connexin-36 contributes to control function of insulin-producing cells
    • Le Gurun S, Martin D, Formenton A, Maechler P, Caille D, et al. (2003) Connexin-36 contributes to control function of insulin-producing cells. J Biol Chem 278: 37690-37697.
    • (2003) J Biol Chem , vol.278 , pp. 37690-37697
    • Le Gurun, S.1    Martin, D.2    Formenton, A.3    Maechler, P.4    Caille, D.5
  • 50
    • 0023374546 scopus 로고    scopus 로고
    • Foulis AK (1987) C. L. Oakley lecture (1987). The pathogenesis of beta cell destruction in type I (insulin-dependent) diabetes mellitus. J Pathol 152: 141-148.
    • Foulis AK (1987) C. L. Oakley lecture (1987). The pathogenesis of beta cell destruction in type I (insulin-dependent) diabetes mellitus. J Pathol 152: 141-148.
  • 51
    • 0026332776 scopus 로고
    • Does insulitis have importance in the pathogenesis of type-1 diabetes in man?]
    • Linn T, Federlin K (1991) [Does insulitis have importance in the pathogenesis of type-1 diabetes in man?]. Immun Infekt 19: 164-166.
    • (1991) Immun Infekt , vol.19 , pp. 164-166
    • Linn, T.1    Federlin, K.2
  • 52
    • 76549198972 scopus 로고
    • Pathologic anatomy of the pancreas in juvenile diabetes mellitus
    • Gepts W (1965) Pathologic anatomy of the pancreas in juvenile diabetes mellitus. Diabetes 14: 619-633.
    • (1965) Diabetes , vol.14 , pp. 619-633
    • Gepts, W.1
  • 55
    • 33750579841 scopus 로고    scopus 로고
    • Glucose induces opposite intracellular Ca2+ concentration oscillatory patterns in identified alpha- and beta-cells within intact human islets of Langerhans
    • Quesada I, Todorova MG, Alonso-Magdalena P, Beltra M, Carneiro LM, et al. (2006) Glucose induces opposite intracellular Ca2+ concentration oscillatory patterns in identified alpha- and beta-cells within intact human islets of Langerhans. Diabetes 55: 2463-2469.
    • (2006) Diabetes , vol.55 , pp. 2463-2469
    • Quesada, I.1    Todorova, M.G.2    Alonso-Magdalena, P.3    Beltra, M.4    Carneiro, L.M.5
  • 56
    • 1942438964 scopus 로고    scopus 로고
    • Gap junctions and the connexin protein family
    • Sohl G, Willecke K (2004) Gap junctions and the connexin protein family. Cardiovasc Res 62: 228-232.
    • (2004) Cardiovasc Res , vol.62 , pp. 228-232
    • Sohl, G.1    Willecke, K.2
  • 57
    • 0023658406 scopus 로고
    • Evidence for modulation of cell-to-cell electrical coupling by cAMP in mouse islets of Langerhans
    • Santos RM, Rojas L (1987) Evidence for modulation of cell-to-cell electrical coupling by cAMP in mouse islets of Langerhans. FEBS Lett 220: 342-346.
    • (1987) FEBS Lett , vol.220 , pp. 342-346
    • Santos, R.M.1    Rojas, L.2
  • 58
    • 33846839283 scopus 로고    scopus 로고
    • Diabetes Care
    • Prediction of clinical outcome in islet allotransplantation
    • Bertuzzi F, Ricordi C (2007) Prediction of clinical outcome in islet allotransplantation. Diabetes Care 30: 410-417.
    • (2007) , vol.30 , pp. 410-417
    • Bertuzzi, F.1    Ricordi, C.2
  • 59
    • 0025106097 scopus 로고
    • Islet somatostatin-microvascular, paracrine, and pulsatile regulation
    • Samols L, Stagner JI (1990) Islet somatostatin-microvascular, paracrine, and pulsatile regulation. Metabolism 39: 55-60.
    • (1990) Metabolism , vol.39 , pp. 55-60
    • Samols, L.1    Stagner, J.I.2
  • 60
    • 10044256230 scopus 로고    scopus 로고
    • Calcium and glycolysis mediate multiple bursting modes in pancreatic islets
    • Bertram R, Satin L, Zhang M, Smolen P, Sherman A (2004) Calcium and glycolysis mediate multiple bursting modes in pancreatic islets. Biophys J 87: 3074-3087.
    • (2004) Biophys J , vol.87 , pp. 3074-3087
    • Bertram, R.1    Satin, L.2    Zhang, M.3    Smolen, P.4    Sherman, A.5
  • 61
    • 0026653303 scopus 로고
    • Periodicity of insulin secretion comprises multiple cycles with different duration in perfused rat islets
    • Yarimizu K, Kawano N, Ono J, Takaki R (1992) Periodicity of insulin secretion comprises multiple cycles with different duration in perfused rat islets. Diabetes Res Clin Pract 17: 27-32.
    • (1992) Diabetes Res Clin Pract , vol.17 , pp. 27-32
    • Yarimizu, K.1    Kawano, N.2    Ono, J.3    Takaki, R.4
  • 62
    • 0022065722 scopus 로고
    • Role of intrapancreatic ganglia in regulation of periodic insular secretions
    • Stagner JI, Samols E (1985) Role of intrapancreatic ganglia in regulation of periodic insular secretions. Am J Physiol 248: E522-530.
    • (1985) Am J Physiol , vol.248
    • Stagner, J.I.1    Samols, E.2
  • 63
    • 0016284890 scopus 로고
    • Membrane potential of beta-cells in pancreatic islets
    • Meissner HP, Schmelz H (1974) Membrane potential of beta-cells in pancreatic islets. Pflugers Arch 351: 195-206.
    • (1974) Pflugers Arch , vol.351 , pp. 195-206
    • Meissner, H.P.1    Schmelz, H.2
  • 64
    • 0016789935 scopus 로고
    • Electrical characteristics of pancreatic islet cells
    • Matthews EK, Sakamoto Y (1975) Electrical characteristics of pancreatic islet cells. J Physiol 246: 421-437.
    • (1975) J Physiol , vol.246 , pp. 421-437
    • Matthews, E.K.1    Sakamoto, Y.2
  • 65
    • 0002591512 scopus 로고    scopus 로고
    • Electrophysiology of the pancreatic B-cell
    • LeRoith D, Taylor SI, Olefsky JM, eds, Philadelphia: Lippincott-Raven
    • Atwater I, Mears D, Rojas E (1996) Electrophysiology of the pancreatic B-cell. In: LeRoith D, Taylor SI, Olefsky JM, eds. Diabetes Mellitus, A fundamental and clinical test. Philadelphia: Lippincott-Raven.
    • (1996) Diabetes Mellitus, A fundamental and clinical test
    • Atwater, I.1    Mears, D.2    Rojas, E.3
  • 66
    • 33244488502 scopus 로고    scopus 로고
    • Oscillations, intercellular coupling, and insulin secretion in pancreatic Beta cells
    • MacDonald PE, Rorsman P (2006) Oscillations, intercellular coupling, and insulin secretion in pancreatic Beta cells. PLoS Biol 4: e49.
    • (2006) PLoS Biol , vol.4
    • MacDonald, P.E.1    Rorsman, P.2
  • 68
    • 35649001607 scopus 로고
    • A Quantitative Description of Membrane Current and its Application to Conduction and Excitation in Nerve
    • Hodekin AL. Huxlev AF (1952) A Quantitative Description of Membrane Current and its Application to Conduction and Excitation in Nerve. Journal of physiology 117: 500-544.
    • (1952) Journal of physiology , vol.117 , pp. 500-544
    • Hodekin, A.L.1    Huxlev, A.F.2
  • 69
    • 2642542358 scopus 로고    scopus 로고
    • Complex bursting in pancreatic islets: A potential glycolytic mechanism
    • Wierschem K, Bertram R (2004) Complex bursting in pancreatic islets: a potential glycolytic mechanism. J Theor Biol 228: 513-521.
    • (2004) J Theor Biol , vol.228 , pp. 513-521
    • Wierschem, K.1    Bertram, R.2
  • 70
    • 0034700423 scopus 로고    scopus 로고
    • Channel sharing in pancreatic beta -cells revisited: Enhancement of emergent bursting by noise
    • De Vries G, Sherman A (2000) Channel sharing in pancreatic beta -cells revisited: enhancement of emergent bursting by noise. J Theor Biol 207: 513-530.
    • (2000) J Theor Biol , vol.207 , pp. 513-530
    • De Vries, G.1    Sherman, A.2
  • 71
    • 0029024670 scopus 로고
    • A role for calcium release-activated current (CRAC) in cholinergic modulation of electrical activity in pancreatic beta-cells
    • Bertram R, Smolen P, Sherman A, Mears D, Atwater I, et al. (1995) A role for calcium release-activated current (CRAC) in cholinergic modulation of electrical activity in pancreatic beta-cells. Biophys J 68: 2323-2332.
    • (1995) Biophys J , vol.68 , pp. 2323-2332
    • Bertram, R.1    Smolen, P.2    Sherman, A.3    Mears, D.4    Atwater, I.5
  • 72
    • 77956750512 scopus 로고    scopus 로고
    • Phase syncrhonization: From theory to data analysis
    • Moss F, Gielen S, eds, Amsterdam: Elsevier Science. pp
    • Rosenblum M, Pikovsky A, Kurths J, Schafer C, Tass PA (2001) Phase syncrhonization: from theory to data analysis. In: Moss F, Gielen S, eds. Handbook of Biological Physics. Amsterdam: Elsevier Science. pp 279-321.
    • (2001) Handbook of Biological Physics , pp. 279-321
    • Rosenblum, M.1    Pikovsky, A.2    Kurths, J.3    Schafer, C.4    Tass, P.A.5
  • 73
    • 13244294808 scopus 로고    scopus 로고
    • An approach to multivariate phase synchronization analysis and its application to event-related potentials
    • Allefeld C, Kurths J (2004) An approach to multivariate phase synchronization analysis and its application to event-related potentials. International Journal of Bifurcation and Chaos 14: 417-426.
    • (2004) International Journal of Bifurcation and Chaos , vol.14 , pp. 417-426
    • Allefeld, C.1    Kurths, J.2
  • 74
    • 3242697081 scopus 로고    scopus 로고
    • Synchronization and entrainment of cytoplasmic Ca2+ oscillations in cell clusters prepared from single or multiple mouse pancreatic islets
    • Zarkovic M, Henquin JC (2004) Synchronization and entrainment of cytoplasmic Ca2+ oscillations in cell clusters prepared from single or multiple mouse pancreatic islets. Am J Physiol Endocrinol Metab 287: E340-347.
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • Zarkovic, M.1    Henquin, J.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.