Production of functionally active Penicillium chrysogenum isopenicillin N synthase in the yeast Hansenula polymorpha

BMC Biotechnology

Volumn 8, Issue , 2008, Pages

  Gidijala, Loknath ^a   Bovenberg, Roel A L ^b   Klaassen, Paul ^b   van der Klei, Ida J ^a,c   Veenhuis, Marten ^a   Kiel, Jan A K W ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b DSM RESOLVE   (Netherlands)

^c KLUYVER CENTRE FOR GENOMICS OF INDUSTRIAL FERMENTATION   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; FERMENTATION; GENE ENCODING; METABOLISM; YEAST;

CEPHALOSPORIN; PENICILLIN; PENICILLIUM CHRYSOGENUM;

ANTIBIOTICS;

ISOPENICILLIN N SYNTHETASE; PENICILLIN G; OXIDOREDUCTASE; RECOMBINANT PROTEIN;

ARTICLE; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; CYTOSOL; DRUG SYNTHESIS; ENZYME LOCALIZATION; ENZYME SYNTHESIS; FUNGAL CELL CULTURE; FUNGAL STRAIN; FUNGUS GROWTH; GENE EXPRESSION; HANSENULA POLYMORPHA; MICROBODY; NONHUMAN; PENICILLIUM CHRYSOGENUM; PROTEIN FUNCTION; TEMPERATURE DEPENDENCE; CHEMISTRY; ENZYME ACTIVATION; ENZYME STABILITY; GENETICS; METABOLISM; METHODOLOGY; PICHIA; PROTEIN ENGINEERING;

BACTERIA (MICROORGANISMS); FUNGI; PENICILLIUM CHRYSOGENUM; PICHIA ANGUSTA;

ENZYME ACTIVATION; ENZYME STABILITY; OXIDOREDUCTASES; PENICILLIUM CHRYSOGENUM; PICHIA; PROTEIN ENGINEERING; RECOMBINANT PROTEINS;

EID: 41549147245     PISSN: None     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/1472-6750-8-29     Document Type: Article

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