Synthesis of 1,4-benzothiazin-2-yl derivatives of 1,3-dicarbonyl compounds and benzothiazinone spiro derivatives by the reaction of 2-chloro-1,4-benzothiazin-3-ones with 'push-pull' enamines

Tetrahedron

Volumn 64, Issue 19, 2008, Pages 4478-4485

  Nazarenko, Konstantin G ^a   Shtil, Nataliya A ^a   Buth, Sergey A ^a   Chernega, Alexander N ^a   Lozinskii, Miron O ^a   Tolmachev, Andrey A ^b  

^a INSTITUTE OF ORGANIC CHEMISTRY   (Ukraine)

^b TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV   (Ukraine)

Author keywords

Chloro derivatives; Electrophilic substitution; Enamines; Rearrangement; Spiro heterocycles

Indexed keywords

2 (1 BENZOYL 2 MORPHOLIN 4 YLPROP 1 EN 1 YL) 2H 1,4 BENZOTHIAZIN 3 (4H) ONE; 2 (1 BENZOYL 2 MORPHOLIN 4 YLPROP 2 EN 1 YL) 2H 1,4 BENZOTHIAZIN 3(4H) ONE; 2 (3 OXO 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 2 YL) 1 PHENYLBUTANE 1,3 DIONE; 3 (3 OXO 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 2 YL) PENTANE 2,4 DIONE; BENZOTHIAZINE DERIVATIVE; CARBONYL DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; ENAMINE; ETHYL 1',5' DIMETHYL 2',3 DIOXO 1'2'3,4 TETRAHYDROSPIRO [1,4 BENZOTHIAZINE 2,3' PYRROLE] 4' CARBOXYLATE; ETHYL 11 ETHYL 2,3 DIMETHYL 4 OXO 2,3,4,5 TETRAHYDRO 1H 2,5 METHANO 6,1,3 BENZOTHIADIAZOCINE 11 CARBOXYLATE; ETHYL 2 (1 BENZOYL 2 MORPHOLIN 4 YLPROP 2 EN 1 YL) 3 OXO 3,4 DIHYDRO 2H 1,4 BENZOTHIAZINE 2 CARBOXYLATE; ETHYL 2 (1 BENZOYL 2 OXOPROPYL) 3 OXO 3,4 DIHYDRO 2H 1,4 BENZOTHIAZINE 2 CARBOXYLATE; ETHYL 2 ETHYL 3 (METHYLIMINO) 2 (3 OXO 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 2 YL) BUTANOATE; ETHYL 3 (METHYLAMINO) 2 (3 OXO 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 2 YL)BUT 2 ENOATE; ETHYL 3 AMINO 2 (3 OXO 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 2 YL)BUT 2 ENOATE; ETHYL 3 OXO 2 (3 OXO 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 2 YL)BUTANOATE; ETHYL 4' ETHYL 1' METHYL 5' METHYLENE 2'3 DIOXO 3,4 DIHYDROSPIRO[1,4 BENZOTHIAZINE 2,3' PYRROLIDINE] 4' CARBOXYLATE; ETHYL 5' METHYL 2',3 DIOXO 1'2'3,4 TETRAHYDROSPIRO [1,4 BENZOTHIAZINE 2,3' PYRROLE] 4' CARBOXYLATE; KETONE DERIVATIVE; TRIETHYLAMINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; HYDROLYSIS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; REACTION ANALYSIS; SYNTHESIS; X RAY DIFFRACTION;

EID: 41549109692     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.02.049     Document Type: Article

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