Reaction of unsymmetrical trifluoromethyl-containing 1,3-dicarbonyl compounds with 'push-pull' enamines

Tetrahedron Letters

Volumn 48, Issue 15, 2007, Pages 2775-2779

  Sibgatulin, Dmitriy A ^a   Volochnyuk, Dmitriy M ^a   Kostyuk, Alexander N ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY   (Ukraine)

Author keywords

'Push pull' enamines; 4,4,4 Trifluoroacetoacetate; Cyclocondensation; Trifluoromethylated benzenes

Indexed keywords

1 [2 METHYL 6 PYRROLIDIN 1 YL 4 (TRIFLUOROMETHYL)PHENYL]ETHANONE; 1 [3 METHYL 5 (TRIFLUOROMETHYL)PHENYL]PYRROLIDINE; [2 METHYL 6 PYRROLIDIN 1 YL 4 (TRIFLUOROMETHYL)PHENYL]PHENYLMETHANONE; CARBONYL DERIVATIVE; DIETHYL 5 HYDROXY 3 MORPHOLIN 4 YL 5 (TRIFLUOROMETHYL)HEPT 2 ENEDIOATE; DIETHYL 5 HYDROXY 3 PYRROLIDIN 1 YL 5 (TRIFLUOROMETHYL)HEPT 2 ENEDIOATE; ENAMINE; ETHYL (5 PYRROLIDIN 1 YL) 3 (TRIFLUOROMETHYL) 1,1' BIPHENYL 2 CARBOXYLATE; ETHYL 2 [4 ETHOXY 2 HYDROXY 4 OXO 2 (TRIFLUOROMETHYL)BUTYL] 4 PYRROLIDIN 1 YL 6 (TRIFLUOROMETHYL)BENZOATE; ETHYL 2 METHYL 4 (4 MORPHOLINYL) 6 (TRIFLUOROMETHYL)BENZOATE; ETHYL 2 METHYL 4 PYRROLIDIN 1 YL 6 (TRIFLUOROMETHYL)BENZOATE; METHYL GROUP; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION KINETICS; DRUG STRUCTURE; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

EID: 33947142444     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.02.044     Document Type: Article

References (21)

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17. 6: C, 50.13; H, 6.31; N, 3.65. Found C, 50.09; H, 6.33; N, 3.66.
18. 3: C, 56.78; H, 5.72; N, 4.41. Found C, 56.80; H, 5.74; N, 4.39.
19. 2: C, 66.11; H, 5.55; N, 3.85. Found C, 66.14; H, 5.54; N, 3.87.
20. 3NO: C, 61.99; H, 5.94; N, 5.16. Found C, 62.01; H, 5.95; N, 5.17.
21. 3NO: C, 68.46; H, 5.44; N, 4.20. Found C, 68.45; H, 5.42; N, 4.18.