Applications of computer-aided pharmacokinetic and pharmacodynamic methods from drug discovery through registration

Current Computer-Aided Drug Design

Volumn 4, Issue 1, 2008, Pages 54-66

  Dong, Jennifer Q ^a   Chen, Bin ^a   Gibbs, Megan A ^a   Emery, Maurice ^a   Gibbs, John P ^a  

^a AMGEN INC   (United States)

Author keywords

Discovery; Drug development; Pharmacodynamics; Pharmacokinetics; PK PD; Software applications

Indexed keywords

APPLICATION PROGRAMS; INFORMATION MANAGEMENT; MATLAB;

COMPUTER-AIDED; DISCOVERY; DRUG DEVELOPMENT; DRUG DISCOVERY; EXPOSURE-RESPONSE RELATIONSHIPS; MODEL AND SIMULATION; PHARMACOKINETICS AND PHARMACODYNAMICS; PHARMACOLOGICAL EFFECTS; PK/PD; SOFTWARE APPLICATIONS;

PHARMACOKINETICS;

3 [3 (3 METHOXYPHENYL) 2 PROPYNYLOXYIMINO] 1 AZABICYCLO[2.2.1]HEPTANE; ANTINEOPLASTIC AGENT; CORTICOSTEROID; EXENDIN 4; PERTUZUMAB; PLACEBO;

CLINICAL STUDY; CLINICAL TRIAL; COMPUTER AIDED DESIGN; COMPUTER MODEL; COMPUTER PROGRAM; COMPUTER SIMULATION; DRUG DESIGN; DRUG DISPOSITION; DRUG EFFECT; DRUG EFFICACY; DRUG EXPOSURE; DRUG RESPONSE; DRUG SAFETY; HUMAN; PHARMACODYNAMICS; PHARMACOKINETICS; PREDICTION; REVIEW;

EID: 41549108007     PISSN: 15734099     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340908783769283     Document Type: Review

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