-
1
-
-
14444280360
-
Pharmacodynamics of immediate and delayed effects of paclitaxel: Role of slow apoptosis and intracellular drug retention
-
Au JLS, Li D, Gan Y, Gao X, Johnson AL, Johnston J, Millenbaugh NJ, Jang SH, Kuh HJ, Chen CT and Wientjes MG (1998) Pharmacodynamics of immediate and delayed effects of paclitaxel: Role of slow apoptosis and intracellular drug retention. Cancer Res 58:2141-2148.
-
(1998)
Cancer Res
, vol.58
, pp. 2141-2148
-
-
Au, J.L.S.1
Li, D.2
Gan, Y.3
Gao, X.4
Johnson, A.L.5
Johnston, J.6
Millenbaugh, N.J.7
Jang, S.H.8
Kuh, H.J.9
Chen, C.T.10
Wientjes, M.G.11
-
2
-
-
0028354777
-
Characterization of a human myeloid leukemia cell line highly resistant to taxol
-
Bhalla K, Huang Y, Tang C, Self S, Ray S, Mahoney ME, Ponnathpur V, Tourkina E, Ibrado AM, Bullock G and Willingham MC (1994) Characterization of a human myeloid leukemia cell line highly resistant to taxol. Leukemia 8:465-475.
-
(1994)
Leukemia
, vol.8
, pp. 465-475
-
-
Bhalla, K.1
Huang, Y.2
Tang, C.3
Self, S.4
Ray, S.5
Mahoney, M.E.6
Ponnathpur, V.7
Tourkina, E.8
Ibrado, A.M.9
Bullock, G.10
Willingham, M.C.11
-
3
-
-
0025935235
-
Restoration of daunomycin retention in multidrug-resistant P388 cells by submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative
-
Boesch D, Muller K, Pourtier-Manzanedo A and Loor F (1991) Restoration of daunomycin retention in multidrug-resistant P388 cells by submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative. Exp Cell Res 196:26-32.
-
(1991)
Exp Cell Res
, vol.196
, pp. 26-32
-
-
Boesch, D.1
Muller, K.2
Pourtier-Manzanedo, A.3
Loor, F.4
-
4
-
-
0028844581
-
Expression of multidrug resistance-associated protein in NIH/3T3 cells confers multidrug resistance associated with increased drug efflux and altered intracellular drug distribution
-
Breuninger LM, Paul S, Gaughan K, Miki T, Chan A, Aaronson SA and Kruh GD (1995) Expression of multidrug resistance-associated protein in NIH/3T3 cells confers multidrug resistance associated with increased drug efflux and altered intracellular drug distribution. Cancer Res 55:5342-5347.
-
(1995)
Cancer Res
, vol.55
, pp. 5342-5347
-
-
Breuninger, L.M.1
Paul, S.2
Gaughan, K.3
Miki, T.4
Chan, A.5
Aaronson, S.A.6
Kruh, G.D.7
-
5
-
-
0022271586
-
Effect of taxol on microtubule organization in mouse splenic lymphocytes and on response to mitogenic stimulation
-
Brown DL, Little JE, Chaly N, Schweitzer I and Paulin-Levasseur M (1985) Effect of taxol on microtubule organization in mouse splenic lymphocytes and on response to mitogenic stimulation. Eur J Cell Biol 37:130-139.
-
(1985)
Eur J Cell Biol
, vol.37
, pp. 130-139
-
-
Brown, D.L.1
Little, J.E.2
Chaly, N.3
Schweitzer, I.4
Paulin-Levasseur, M.5
-
6
-
-
0021367846
-
Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death
-
Cohen JJ and Duke RC (1984) Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. J Immunol 132:38-42.
-
(1984)
J Immunol
, vol.132
, pp. 38-42
-
-
Cohen, J.J.1
Duke, R.C.2
-
7
-
-
0028908695
-
Substoichiometric binding of taxol suppresses microtubule dynamics
-
Derry WB, Wilson L and Jordan MA (1995) Substoichiometric binding of taxol suppresses microtubule dynamics. Biochemistry 34:2203-2211.
-
(1995)
Biochemistry
, vol.34
, pp. 2203-2211
-
-
Derry, W.B.1
Wilson, L.2
Jordan, M.A.3
-
8
-
-
0030022120
-
Resistance mechanisms in human sarcoma mutants derived by single-step exposure to paclitaxel (Taxol)
-
Dumontet C, Duran GE, Steger KA, Beketic-Oreskovic L and Sikic BI (1996) Resistance mechanisms in human sarcoma mutants derived by single-step exposure to paclitaxel (Taxol). Cancer Res 56:1091-1097.
-
(1996)
Cancer Res
, vol.56
, pp. 1091-1097
-
-
Dumontet, C.1
Duran, G.E.2
Steger, K.A.3
Beketic-Oreskovic, L.4
Sikic, B.I.5
-
9
-
-
0033052777
-
Mechanisms of action of and resistance to antitubulin agents: Microtubule dynamics, drug transport, and cell death
-
Dumontet C and Sikic BI (1999) Mechanisms of action of and resistance to antitubulin agents: Microtubule dynamics, drug transport, and cell death. J Clin Oncol 17:1061-1070.
-
(1999)
J Clin Oncol
, vol.17
, pp. 1061-1070
-
-
Dumontet, C.1
Sikic, B.I.2
-
10
-
-
0025313475
-
Multidrug resistance in cells transfected with human genes encoding a variant P-glycoprotein and glutathione S-transferase-π
-
Fairchild CR, Moscow JA, O'Brien EE and Cowan KH (1990) Multidrug resistance in cells transfected with human genes encoding a variant P-glycoprotein and glutathione S-transferase-π. Mol Pharmacol 37:801-809.
-
(1990)
Mol Pharmacol
, vol.37
, pp. 801-809
-
-
Fairchild, C.R.1
Moscow, J.A.2
O'Brien, E.E.3
Cowan, K.H.4
-
11
-
-
0029417352
-
Altered expression of Mβ2. The class II β-tubulin isotype, in a murine J774.2 cell line with a high level of taxol resistance
-
Haber M, Burkhart CA, Regl DL, Madafiglio J, Norris MD and Horwitz SB (1995) Altered expression of Mβ2. the class II β-tubulin isotype, in a murine J774.2 cell line with a high level of taxol resistance. J Biol Chem 270:31269-31275.
-
(1995)
J Biol Chem
, vol.270
, pp. 31269-31275
-
-
Haber, M.1
Burkhart, C.A.2
Regl, D.L.3
Madafiglio, J.4
Norris, M.D.5
Horwitz, S.B.6
-
12
-
-
0000991611
-
Kinetics and mathematical modeling of paclitaxel efflux by p-glycoprotein in BC19 cells
-
Jang SH, Kuh HJ, Wientjes MG and Au JLS (1998) Kinetics and mathematical modeling of paclitaxel efflux by p-glycoprotein in BC19 cells. Proc Am Assoc Cancer Res 39:218.
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 218
-
-
Jang, S.H.1
Kuh, H.J.2
Wientjes, M.G.3
Au, J.L.S.4
-
13
-
-
0028158664
-
Synergistic interaction between cisplatin and taxol in human ovarian carcinoma cells in vitro
-
Jekunen AP, Christen RD, Shalinsky DR and Howell SB (1994) Synergistic interaction between cisplatin and taxol in human ovarian carcinoma cells in vitro. Br J Cancer 69:299-306.
-
(1994)
Br J Cancer
, vol.69
, pp. 299-306
-
-
Jekunen, A.P.1
Christen, R.D.2
Shalinsky, D.R.3
Howell, S.B.4
-
14
-
-
0025824979
-
Mechanism of inhibition of cell proliferation by vinca alkaloids
-
Jordan MA, Thrower D and Wilson L (1991) Mechanism of inhibition of cell proliferation by vinca alkaloids. Cancer Res 51:2212-2222.
-
(1991)
Cancer Res
, vol.51
, pp. 2212-2222
-
-
Jordan, M.A.1
Thrower, D.2
Wilson, L.3
-
15
-
-
0027360552
-
Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations
-
Jordan MA, Toso RJ, Thrower D and Wilson L (1993) Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Proc Natl Acad Sci USA 90:9552-9556
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 9552-9556
-
-
Jordan, M.A.1
Toso, R.J.2
Thrower, D.3
Wilson, L.4
-
16
-
-
0030020158
-
Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death
-
Jordan MA, Wendell K, Gardiner S, Derry WB, Copp H and Wilson L (1996) Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death. Cancer Res 56:816-825.
-
(1996)
Cancer Res
, vol.56
, pp. 816-825
-
-
Jordan, M.A.1
Wendell, K.2
Gardiner, S.3
Derry, W.B.4
Copp, H.5
Wilson, L.6
-
17
-
-
0029044165
-
Paclitaxel pharmacokinetics and pharmacodynamics
-
Kearns CM, Gianni L and Egorin MJ (1995) Paclitaxel pharmacokinetics and pharmacodynamics. Semin Oncol 22 (Suppl 6):16-23.
-
(1995)
Semin Oncol
, vol.22
, Issue.SUPPL. 6
, pp. 16-23
-
-
Kearns, C.M.1
Gianni, L.2
Egorin, M.J.3
-
19
-
-
0032789521
-
Determinants of paclitaxel penetration and accumulation in human solid tumor
-
Kuh HJ, Jang SH, Wientjes MG, Weaver JR and Au JLS (1999) Determinants of paclitaxel penetration and accumulation in human solid tumor. J Pharmacol Exp Ther 290:871-880.
-
(1999)
J Pharmacol Exp Ther
, vol.290
, pp. 871-880
-
-
Kuh, H.J.1
Jang, S.H.2
Wientjes, M.G.3
Weaver, J.R.4
Au, J.L.S.5
-
20
-
-
0027762115
-
Stability problem with taxol in mouse plasma during analysis by liquid chromatography
-
Leslie J, Kujawa JM, Eddington N, Egorin M and Eiseman J (1993) Stability problem with taxol in mouse plasma during analysis by liquid chromatography. J Pharm Biomed Anal 11:1349-1352.
-
(1993)
J Pharm Biomed Anal
, vol.11
, pp. 1349-1352
-
-
Leslie, J.1
Kujawa, J.M.2
Eddington, N.3
Egorin, M.4
Eiseman, J.5
-
21
-
-
0000216533
-
P-glycoprotein overexpression increases maximum induction of apoptosis by taxol
-
Li D, Koo KL and Au JLS (1998) P-glycoprotein overexpression increases maximum induction of apoptosis by taxol. Proc Am Assoc Cancer Res 39:217.
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 217
-
-
Li, D.1
Koo, K.L.2
Au, J.L.S.3
-
22
-
-
0027517847
-
Cytotoxic studies of paclitaxel (Taxol) in human tumour cell lines
-
Liebmann JE, Cook JA, Lipschultz C, Teague D, Fisher J and Mitchell JB (1993) Cytotoxic studies of paclitaxel (Taxol) in human tumour cell lines. Br J Cancer 68:1104-1109.
-
(1993)
Br J Cancer
, vol.68
, pp. 1104-1109
-
-
Liebmann, J.E.1
Cook, J.A.2
Lipschultz, C.3
Teague, D.4
Fisher, J.5
Mitchell, J.B.6
-
23
-
-
0027238859
-
Cell kill kinetics and cell cycle effects of taxol on human and hamster ovarian cell lines
-
Lopes NM, Adams EG, Pitts TW and Bhuyan BK (1993) Cell kill kinetics and cell cycle effects of taxol on human and hamster ovarian cell lines. Cancer Chemother Pharmacol 32:235-242.
-
(1993)
Cancer Chemother Pharmacol
, vol.32
, pp. 235-242
-
-
Lopes, N.M.1
Adams, E.G.2
Pitts, T.W.3
Bhuyan, B.K.4
-
25
-
-
0028906559
-
Kinetics of mitotic arrest and apoptosis in murine mammary and ovarian tumors treated with taxol
-
Milas L, Hunter NR, Kurdoglu B, Mason KA, Meyn RE, Stephens LC and Peters LJ (1995) Kinetics of mitotic arrest and apoptosis in murine mammary and ovarian tumors treated with taxol. Cancer Chemother Pharmacol 35:297-303.
-
(1995)
Cancer Chemother Pharmacol
, vol.35
, pp. 297-303
-
-
Milas, L.1
Hunter, N.R.2
Kurdoglu, B.3
Mason, K.A.4
Meyn, R.E.5
Stephens, L.C.6
Peters, L.J.7
-
26
-
-
0001903946
-
The cell cytoskeleton: Possible role in volume control
-
Mills JW (1987) The cell cytoskeleton: Possible role in volume control. Curr Top Membr Transp 30:75-101.
-
(1987)
Curr Top Membr Transp
, vol.30
, pp. 75-101
-
-
Mills, J.W.1
-
27
-
-
0019859353
-
Taxol binds to polymerized tubulin in vitro
-
Parness J and Horwitz SB (1981) Taxol binds to polymerized tubulin in vitro. J Cell Biol 91:479-487.
-
(1981)
J Cell Biol
, vol.91
, pp. 479-487
-
-
Parness, J.1
Horwitz, S.B.2
-
28
-
-
0031985608
-
Altered beta-tubulin isotype expression in paclitaxel-resistant human prostate carcinoma cells
-
Ranganathan S, Benetatos CA, Colarusso PJ, Dexter DW and Hudes GR (1998) Altered beta-tubulin isotype expression in paclitaxel-resistant human prostate carcinoma cells. Br J Cancer 77:562-566.
-
(1998)
Br J Cancer
, vol.77
, pp. 562-566
-
-
Ranganathan, S.1
Benetatos, C.A.2
Colarusso, P.J.3
Dexter, D.W.4
Hudes, G.R.5
-
29
-
-
0023199652
-
Taxol is converted to 7-epitaxol, a biologically active isomer, in cell culture medium
-
Ringel I and Horwitz SB (1987) Taxol is converted to 7-epitaxol, a biologically active isomer, in cell culture medium. J Pharmacol Exp Ther 242:692-698.
-
(1987)
J Pharmacol Exp Ther
, vol.242
, pp. 692-698
-
-
Ringel, I.1
Horwitz, S.B.2
-
30
-
-
0000076620
-
Cellular uptake and efflux of docetaxel (taxotere) and paclitaxel (taxol) in P388 cell line
-
Riou JF, Retitgenet O, Combeau C and Lavelle F (1994) Cellular uptake and efflux of docetaxel (taxotere) and paclitaxel (taxol) in P388 cell line. Proc Am Assoc Cancer Res 35:160.
-
(1994)
Proc Am Assoc Cancer Res
, vol.35
, pp. 160
-
-
Riou, J.F.1
Retitgenet, O.2
Combeau, C.3
Lavelle, F.4
-
31
-
-
0025014597
-
Development of polyploidization in taxol-resistant human leukemia cells in vitro
-
Roberts JR, Allison DC, Donehower RC and Rowinsky EK (1990) Development of polyploidization in taxol-resistant human leukemia cells in vitro. Cancer Res 50:710-716.
-
(1990)
Cancer Res
, vol.50
, pp. 710-716
-
-
Roberts, J.R.1
Allison, D.C.2
Donehower, R.C.3
Rowinsky, E.K.4
-
33
-
-
0023809123
-
Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol
-
Rowinsky EK, Donehower RC, Jones RJ and Tucker RW (1988) Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol. Cancer Res 48:4093-4100.
-
(1988)
Cancer Res
, vol.48
, pp. 4093-4100
-
-
Rowinsky, E.K.1
Donehower, R.C.2
Jones, R.J.3
Tucker, R.W.4
-
34
-
-
0030032306
-
Binding of taxol to plastic and glass containers and proteins under in vitro conditions
-
Song D, Hsu LF and Au JLS (1996) Binding of taxol to plastic and glass containers and proteins under in vitro conditions. J Pharm Sci 85:29-31.
-
(1996)
J Pharm Sci
, vol.85
, pp. 29-31
-
-
Song, D.1
Hsu, L.F.2
Au, J.L.S.3
-
35
-
-
0028217279
-
P-glycoprotein binding and modulation of the multidrug resistant phenotype by estramustine
-
Speicher LA, Barone LR, Chapman AE, Hudes GR, Laing N, Smith CD and Tew KD (1994) P-glycoprotein binding and modulation of the multidrug resistant phenotype by estramustine. J Natl Cancer Inst 86:688-694.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 688-694
-
-
Speicher, L.A.1
Barone, L.R.2
Chapman, A.E.3
Hudes, G.R.4
Laing, N.5
Smith, C.D.6
Tew, K.D.7
-
36
-
-
0025967252
-
Quantitation of cellular tubulin in microtubules and tubulin pools by a competitive ELlSA
-
Thrower D, Jordan MA and Wilson L (1991) Quantitation of cellular tubulin in microtubules and tubulin pools by a competitive ELlSA. J Immunol Methods 138:45-51.
-
(1991)
J Immunol Methods
, vol.138
, pp. 45-51
-
-
Thrower, D.1
Jordan, M.A.2
Wilson, L.3
|