Exogenous DNA can be captured by stem cells and be involved in their rescue from death after lethal-dose γ-radiation

Gene Therapy and Molecular Biology

Volumn 11, Issue 2, 2007, Pages 305-314

  Likhacheva, Anastasia S ^a   Nikolin, Valeriy P ^a   Popova, Nelly A ^a   Rogachev, Vladimir A ^a   Prokhorovich, Maria A ^a   Sebeleva, Tamara E ^a   Bogachev, Sergei S ^a,b,c   Shurdov, Mikhail A ^b  

^a INSTITUTE OF CYTOLOGY AND GENETICS   (Russian Federation)

^b LLC Panagen ^*  (Russian Federation)

^c NONE   (Russian Federation)

Author keywords

DNA uptake; Exogenous DNA; Gene therapy; Radioprotection; Stem cells

Indexed keywords

MUS;

EID: 41449096799     PISSN: 15299120     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Abaji C, Cousineau I, and Belmaaza A (2005) BRCA2 regulates homologous recombination in response to DNA damage: implications for genome stability and carcinogenesis. Cancer Res 65,4117-4125.
2. Baricheva EA, Berrios M, Bogachev SS, Borisevich IV, Lapik ER, Sharakhov IV, Stuurman N, and Fisher PA (1996) DNA from Drosophila melanogaster beta-heterochromatin binds specifically to nuclear lamins in vitro and the nuclear envelope in situ. Gene 171, 171-176.
3. Bartsch S, Kang LE, and Symington LS (2000) RAD 51 is required for the repair of plasmid double-stranded DNA gaps from either plasmid or chromosomal templates. Mol Cell Biol 20, 1194-1205.
4. Benett R, Garbor GT, and Merritt MM (1985) DNA binding to human leukocytes. J Clin Invest 76, 2182-2190.
5. Bonner WM (2003) Low-dose radiation: thresholds, bystander effects, and adaptive responses. Proc Natl Acad Sci USA 100, 4973-4975.
6. Chelobanov BP, Lactionov PP, and Vlasov VV (2006) Proteins involved in binding and uptake of nucleic acids by the cell. Biochemistry 71, 725-741. In Russian.
7. DNA cloning: a practical approach. Volume I, II. (1985) Edited by Glover DM. Oxford-Washington, DC: IRL Press.
8. Drosophila: a practical approach. (1986) Edited by Roberts DB. Oxford-Washington, DC: IRL Press. 295 pp.
9. Histology, cytology and embryology. (2004) Edited by Afanasiev YI, Kuznetsov SL, Yurina NA. M: Medicine. 768 pp.
10. Lawen A (2003) Apoptosis - an introduction. Bioessays 25, 888-896.
11. Ledoux L (1965) Uptake of DNA by living cells. Prog Nucleic Acid Res Mol Biol 4, 231-267.
12. Likhacheva AS, Nikolin VP, Popova NA, Dubatolova TD, Strunkin DN, Rogachev VA, Sebeleva TE, Erofeev IS, Bogachev SS, Yakubov LA, and Shurdov MA (2007) Integration of human DNA fragments into the cell genomes of certain tissues from adult mice treated with cytostatic cyclophosphamide in combination with human DNA. Gene Ther Mol Biol 11, 185-202.
13. Lin J, Krishnaraj K, and Kemp RG (1985) Exogenous ATP enhances calcium influx in intact thymocytes. J Immunol 135, 3403-3410.
14. Loke SL, Stein CA, Zhang XH, Moir K, Nakanishi M, Subasinghe C, Cohen JS, and Neckers LM (1989) Characterization of oligonucleotide transport in to living cells. Proc Natl Acad Sci USA 86, 3474-3478.
15. Niedernhofer LJ, Odijk H, Budzowska M, van Drunen E, Maas A, Theil AF, de Wit J, Jaspers NG, Beverloo HB, Hoeijmakers JH, and Kanaar R (2004) The structure-specific endonuclease Erccl-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks. Mol Cell Biol 24, 5776-5787.
16. Peterson CL, Cote J (2004) Cellular machineries for chromosomal DNA repair. Genes Dev 18, 602-616.
17. Rodrigue A, Lafrance M, Gauthier MC, McDonald D, Hendzel M, West SC, Jasin M, and Masson JY (2006) Interplay between human DNA repair proteins at a unique double-strand break in vivo. EMBO J 25, 222-231.
18. Rogachev VA, Likhacheva A, Vratskikh O, Mechetina LV, Sebeleva TE, Bogachev SS, Yakubov LA, and Shurdov MA (2006) Qualitative and quantitative characteristics of the extracellular DNA delivered to the nucleus of a living cell. Cancer Cell Int 6.
19. Rogakou EP, Boon C, Redon C, and Bonner WM (1999) Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 146, 905-916.
20. Savill J, Fadok V, Henson P, and Haslett C (1993) Phagocyte recognition of cells undergoing apoptosis. Immunol Today 14, 131.
21. Scott SP, Pandita TK (2006) The cellular control of DNA double-strand breaks. J Cell Biochem 99, 1463-1475.
22. Shestova OE, Andreeva AY, Vlasov VV, and Yakubov LA (1999) Transport of complexes of oligonucleotides with cell-surface proteins to the cell nucleus. Dokl Akad Nauk 368, 264-267. In Russian.
23. Stiff T, O'Driscoll M, Rief N, Iwabuchi K, Lobrich M, and Jeggo PA ( 2004) ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res 64, 2390-2396.
24. Symington LS (2005) Focus on recombinational DNA repair. EMBO Rep 6, 512-517.
25. Takata M, Sasaki MS, Sonoda E, Fukushima T, Morrison C, Albala JS, Swagemakers SM, Kanaar R, Thompson LH, and Takeda S (2000) The RAD 51 paralog RAD 51B promotes homologous recombinational repair. Mol Cell Biol 20, 6476-6482.
26. Takata M, Sasaki MS, Tachiiri S, Fukushima T, Sonoda E, Schild D, Thompson LH, and Takeda S (2001) Chromosome instability and defective recombinational repair in knockout mutants of the five RAD 51 paralogs. Mol Cell Biol 21, 2858-2866.
27. Yakubov LA, Petrova NA, Popova NA, Nikolin VP, and Os'kina IN (2002) The role of extracellular DNA in the stability and variability of cell genomes. Dokl Biochem Biophys 382, 31-34.
28. Yakubov LA, Popova NA, Nikolin VP, Semenov DV, Bogachev SS, and Os'kina IN (2003) Extracellular genomic DNA protects mice against radiation and chemical mutagens. Genome Biol 5,3.
29. Zamecnik P, Aghajanian J, Zamecnik M, Goodchild J, and Witman G (1994) Electron micrographic studies of transport of oligodeoxynucleotides across eukaryotic membranes. Proc Natl Acad Sci USA 91, 3156-3160.