Relocating the active site of activated protein C eliminates the need for its protein S cofactor. A fluorescence resonance energy transfer study

Journal of Biological Chemistry

Volumn 274, Issue 9, 1999, Pages 5462-5468

  Yegneswarani, Subramanian ^a,b   Smirnov, Mikhail D ^c   Safa, Omid ^c   Esmon, Naomi L ^c,d   Esmon, Charles T ^c,d,e   Johnson, Arthur E ^a,f,g  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^d UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^f TEXAS A AND M UNIVERSITY   (United States)

^g TEXAS A M COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN C; PROTEIN S;

AMINO ACID SUBSTITUTION; ARTICLE; CELL MEMBRANE; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME LOCALIZATION; FLUORESCENCE; NONHUMAN; PRIORITY JOURNAL;

BINDING SITES; CHROMATOGRAPHY, GEL; ENERGY TRANSFER; FLUORESCEIN; FLUORESCENCE; HUMANS; MEMBRANES, ARTIFICIAL; PHOSPHOLIPIDS; PROTEIN C; PROTEIN S; SPECTROMETRY, FLUORESCENCE;

EID: 0033605370     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.9.5462     Document Type: Article

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