Activation of SAD kinase by Ca2+/calmodulin-dependent protein kinase kinase

Biochemistry

Volumn 47, Issue 13, 2008, Pages 4151-4159

  Fujimoto, Tomohito ^a   Yurimoto, Saki ^a   Hatano, Naoya ^a   Nozaki, Naohito ^b   Sueyoshi, Noriyuki ^a   Kameshita, Isamu ^a   Mizutani, Akihiro ^c   Mikoshiba, Katsuhiko ^c   Kobayashi, Ryoji ^a   Tokumitsu, Hiroshi ^a  

^a KAGAWA UNIVERSITY   (Japan)

^b KANAGAWA DENTAL COLLEGE   (Japan)

^c RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; ENZYME ACTIVITY; LIGANDS; MASS SPECTROMETRY; PHOSPHORYLATION;

ACTIVATING KINASE; ACTIVATION LOOP; RAT BRAIN;

PROTEINS;

ADENOSINE PHOSPHATE; PROTEIN KINASE; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN KINASE LKB1; THREONINE;

AFFINITY CHROMATOGRAPHY; ARTICLE; BINDING AFFINITY; CELL STRAIN COS7; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME PURIFICATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE; CHROMATOGRAPHY, AFFINITY; CLONING, MOLECULAR; DNA PRIMERS; ENZYME ACTIVATION; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RATS; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 41449084761     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi702528r     Document Type: Article

References (50)

1. Soderling, T. R., and Stull, J. T. (2001) Structure and Regulation of Calcium/Calmodulin-Dependent Protein Kinases. Chem. Rev. 101, 2341-2352.
2. 2+/CaM-dependent kinases: from activation to function. Annu. Rev. Pharmacol. Toxicol. 41, 471-505.
3. 2+/calmodulin-dependent protein kinase cascade. Molecular cloning and expression of calcium/calmodulin-dependent protein kinase kinase. J. Biol. Chem. 270, 19320-19324.
4. 2+- calmodulin-dependent protein kinase Ia kinase. Phosphorylation of threonine 196 is essential for activation. J. Biol. Chem. 270, 17616-17621.
5. Haribabu, B., Hook, S. S., Selbert, M. A., Goldstein, E. G., Tomhave, E. D., Edelman, A. M., Snyderman, R., and Means, A. R. (1995) Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase. EMBO J. 14, 3679-3686.
6. 2+/ calmodulin-dependent protein kinase kinase beta. J. Biol. Chem. 273, 31880-31889.
7. 2+/Calmodulin- dependent protein kinase kinase. Role of the arg-pro-rich insert domain. J. Biol. Chem. 274, 15803-15810.
8. 2+/Calmodulin-dependent protein kinase cascade in Caenorhabditis elegans. Implication in transcriptional activation. J. Biol. Chem. 274, 22556-22562.
9. 2+/CaM-dependent protein kinases required for normal nuclear division in Aspergillus nidulans. J. Biol. Chem. 275, 38230-38238.
10. 2+/calmodulin kinase kinase alpha is dispensable for brain development but is required for distinct memories in male, though not in female, mice. Mol. Cell. Biol. 26, 9094-9104.
11. 2+/calmodulin kinase kinase alpha-deficient mice. Mol. Cell. Biol. 26, 9105-9115.
12. Mizuno, K., Antunes-Martins, A., Ris, L., Peters, M., Godaux, E., and Giese, K. P. (2007) Calcium/calmodulin kinase kinase beta has a male-specific role in memory formation. Neuroscience 145, 393-402.
13. Tokumitsu, H., and Soderling, T. R. (1996) Requirements for calcium and calmodulin in the calmodulin kinase activation cascade. J. Biol. Chem. 271, 5617-5622.
14. 2+/calmodulin-dependent protein kinase kinase. J. Biol. Chem. 273, 21473-21481.
15. 2+/calmodulin-dependent protein kinase kinase. J. Biol. Chem. 275, 20090-20095.
16. 2+-calmodulin-dependent kinase kinase. Nat. Struct. Biol. 6, 819-824.
17. 2+/calmodulin-dependent kinase kinase peptide. J. Mol. Biol. 312, 59-68.
18. Yano, S., Tokumitsu, H., and Soderling, T. R. (1998) Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway. Nature 396, 584-587.
19. 2+/calmodulin activates the calmodulin-dependent protein kinase I cascade, via three independent mechanisms. J. Biol. Chem. 270, 27186-27191.
20. 2+/calmodulin-dependent protein kinase kinase alpha as Snf1-activating kinases in yeast. J. Biol. Chem. 280, 21804-21809.
21. 2+/ calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. Cell Metab. 2, 21-33.
22. 2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases. J. Biol. Chem. 280, 29060-29066.
23. 2+/ calmodulin-dependent protein kinase kinase. J. Biol. Chem. 277, 15813-15818.
24. 2+/calmodulin- dependent protein kinase kinase dictates sensitivity to the specific inhibitor, STO-609. J. Biol. Chem. 278, 10908-10913.
25. 2+/calmodulin-dependent protein kinase kinase isoforms. Biochemistry 40, 13925-13932.
26. Neumann, D., Woods, A., Carling, D., Wallimann, T., and Schlattner, U. (2003) Mammalian AMP-activated protein kinase: functional, heterotrimeric complexes by co-expression of subunits in Escherichia coli. Protein Expression Purif. 30, 230-237.
27. Kimura, K., Nozaki, N., Saijo, M., Kikuchi, A., Ui, M., and Enomoto, T. (1994) Identification of the nature of modification that causes the shift of DNA topoisomerase II beta to apparent higher molecular weight forms in the M phase. J. Biol. Chem. 269, 24523-24526.
28. Kikuchi, M., Hatano, N., Yokota, S., Shimozawa, N., Imanaka, T., and Taniguchi, H. (2004) Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease. J. Biol. Chem. 279, 421-428.
29. Lemrow, S. M., Anderson, K. A., Joseph, J. D., Ribar, T. J., Noeldner, P. K., and Means, A. R. (2004) Catalytic activity is required for calcium/calmodulin-dependent protein kinase IV to enter the nucleus. J. Biol. Chem. 279, 11664-11671.
30. Kishi, M., Pan, Y. A., Crump, J. G., and Sanes, J. R. (2005) Mammalian SAD kinases are required for neuronal polarization. Science 307, 929-932.
31. Barnes, A. P., Lilley, B. N., Pan, Y. A., Plummer, L. J., Powell, A. W., Raines, A. N., Sanes, J. R., and Polleux, F. (2007) LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Cell 129, 549-563.
32. Inoue, E., Mochida, S., Takagi, H., Higa, S., Deguchi-Tawarada, M., Takao-Rikitsu, E., Inoue, M., Yao, I., Takeuchi, K., Kitajima, I., Setou, M., Ohtsuka, T., and Takai, Y. (2006) SAD: a presynaptic kinase associated with synaptic vesicles and the active zone cytomatrix that regulates neurotransmitter release. Neuron 50, 261-275.
33. Lizcano, J. M., Goransson, O., Toth, R., Deak, M., Morrice, N. A., Boudeau, J., Hawley, S. A., Udd, L., Makela, T. P., Hardie, D. G., and Alessi, D. R. (2004) LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. EMBO J. 23, 833-843.
34. Hawley, S. A., Pan, D. A., Mustard, K. J., Ross, L., Bain, J., Edelman, A. M., Frenguelli, B. G., and Hardie, D. G. (2005) Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab. 2, 9-19.
35. Hawley, S. A., Boudeau, J., Reid, J. L., Mustard, K. J., Udd, L., Makela, T. P., Alessi, D. R., and Hardie, D. G. (2003) Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade. J. Biol. 2, 28.
36. Woods, A., Johnstone, S. R., Dickerson, K., Leiper, F. C., Fryer, L. G., Neumann, D., Schlattner, U., Wallimann, T., Carlson, M., and Carling, D. (2003) LKB1 is the upstream kinase in the AMP-activated protein kinase cascade. Curr. Biol. 13, 2004-2008.
37. 2+/calmodulin- dependent protein kinase IV. Identification of a brain CaM-kinase IV kinase. J. Biol. Chem. 269, 28640-28647.
38. Adams, J. A. (2003) Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model? Biochemistry 42, 601-607.
39. Hardie, D. G., Scott, J. W., Pan, D. A., and Hudson, E. R. (2003) Management of cellular energy by the AMP-activated protein kinase system. FEBS Lett. 546, 113-120.
40. Minokoshi, Y., Kim, Y. B., Peroni, O. D., Fryer, L. G., Muller, C., Carling, D., and Kahn, B. B. (2002) Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 415, 339-343.
41. Yamauchi, T., Kamon, J., Minokoshi, Y., Ito, Y., Waki, H., Uchida, S., Yamashita, S., Noda, M., Kita, S., Ueki, K., Eto, K., Akanuma, Y., Froguel, P., Foufelle, F., Ferre, P., Carling, D., Kimura, S., Nagai, R., Kahn, B. B., and Kadowaki, T. (2002) Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat. Med. 8, 1288-1295.
42. Minokoshi, Y., Alquier, T., Furukawa, N., Kim, Y. B., Lee, A., Xue, B., Mu, J., Foufelle, F., Ferre, P., Birnbaum, M. J., Stuck, B. J., and Kahn, B. B. (2004) AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 428, 569-574.
43. Kahn, B. B., Alquier, T., Carling, D., and Hardie, D. G. (2005) AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab. 1, 15-25.
44. Hoyer-Hansen, M., Bastholm, L., Szyniarowski, P., Campanella, M., Szabadkai, G., Farkas, T., Bianchi, K., Fehrenbacher, N., Elling, F., Rizzuto, R., Mathiasen, I. S., and Jaattela, M. (2007) Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. Mol. Cell 25, 193-205.
45. Jensen, T. E., Rose, A. J., Jorgensen, S. B., Brandt, N., Schjerling, P., Wojtaszewski, J. F., and Richter, E. A. (2007) Possible CaMKK-dependent regulation of AMPK phosphorylation and glucose uptake at the onset of mild tetanic skeletal muscle contraction. Am. J. Physiol. Endocrinol. Metab. 292, E1308-E1317.
46. 2+/ calmodulin-dependent protein kinase kinases in the adult rat brain. Brain Res. Mol. Brain Res. 54, 311-315.
47. Shelly, M., Cancedda, L., Heilshorn, S., Sumbre, G., and Poo, M. M. (2007) LKB1/STRAD promotes axon initiation during neuronal polarization. Cell 129, 565-577.
48. Augustine, G. J., Santamaria, F., and Tanaka, K. (2003) Local calcium signaling in neurons. Neuron 40, 331-346.
49. Baas, A. F., Boudeau, J., Sapkota, G. P., Smit, L., Medema, R., Morrice, N. A., Alessi, D. R., and Clevers, H. C. (2003) Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD. EMBO J. 22, 3062-3072.
50. Boudeau, J., Baas, A. F., Deak, M., Morrice, N. A., Kieloch, A., Schutkowski, M., Prescott, A. R., Clevers, H. C., and Alessi, D. R. (2003) MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm. EMBO J. 22, 5102-5114.