Twin DNA pumps of a hexameric helicase provide power to simultaneously melt two duplexes

Molecular Cell

Volumn 15, Issue 3, 2004, Pages 453-465

  Kaplan, Daniel L ^a   O'Donnell, Mike ^a,b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HELICASE; MCM 4 PROTEIN; MCM 6 PROTEIN; MCM 7 PROTEIN; PROTEIN; RUV B PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; DNA BINDING; DNA DAMAGE; DNA STRAND; ENZYME ACTIVITY; EUKARYOTE; HOLLIDAY JUNCTION; PUMP;

ADENOSINE TRIPHOSPHATASES; CELL CYCLE PROTEINS; DNA; DNA HELICASES; DNA, CRUCIFORM; DNAB HELICASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; TIME FACTORS;

ESCHERICHIA COLI; EUKARYOTA;

EID: 4143151757     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2004.06.039     Document Type: Article

References (38)

1. Adams D.E., West S.C. Bypass of DNA heterologies during RuvAB-mediated three- and four-strand branch migration. J. Mol. Biol. 263:1996;582-596
2. Carr K.M., Kaguni J.M. Escherichia coli DnaA protein loads a single DnaB helicase at a DnaA box hairpin. J. Biol. Chem. 277:2002;39815-39822
3. Cox M.M. Recombinational DNA repair in bacteria and the RecA protein. Prog. Nucleic Acid. Res. Mol. Bio. 63:2000;311-366
4. Cromie G.A., Connelly J.C., Leach D.R.F. Recombination at double-strand breaks and DNA ends. conserved mechanisms from phage to humans Mol. Cell. 8:2001;1163-1174
5. Egelman E.H. Homomorphous hexameric helicases. tales from the ring cycle Structure. 4:1996;759-762
6. Eggleston A.K., O'Neill T.E., Bradbury E.M., Kowalczykowski S.C. Unwinding of nucleosomal DNA by a DNA helicase. J. Biol. Chem. 270:1995;2024-2031
7. Fang L., Davey M.J., O'Donnell M. Replisome assembly at oriC, the replication origin of E. coli, reveals an explanation for initiation sites outside an origin. Mol. Cell. 4:1999;541-553
8. Hiom K., West S.C. Branch migration during homologous recombination. assembly of a RuvAB Holliday junction complex in vitro Cell. 80:1995;787-793
9. Ishimi Y. A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex. J. Biol. Chem. 272:1997;24508-24513
10. Jezewska M.J., Kim U.-S., Bujalowski W. Binding of Escherichia coli primary replicative helicase DnaB protein to single-stranded DNA. Long-range allosteric conformational changes within the protein hexamer. Biochemistry. 35:1996;2129-2145
11. Jiao J., Simmons D.T. Nonspecific double-stranded DNA binding activity of simian virus 40 large T antigen is involved in melting and unwinding of the origin. J. Virol. 77:2003;12720-12728
12. Kaplan D.L. The 3′-tail of a forked-duplex sterically determines whether one or two DNA strands pass through the central channel of a replication-fork helicase. J. Mol. Biol. 301:2000;285-299
13. Kaplan D.L., Davey M.J., O'Donnell M. Mcm4,6,7 uses a 'pump in ring' mechanism to unwind DNA by steric exclusion and actively translocate along a duplex. J. Biol. Chem. 278:2003;49171-49182
14. Kaplan D.L., O'Donnell M. DnaB drives DNA branch migration and dislodges proteins while encircling two DNA strands. Mol. Cell. 10:2002;647-657
15. Kim S., Dallmann H.G., McHenry C.S., Marians K.J. Coupling of a replicative polymerase and helicase. a τ-DnaB interaction mediates rapid replication fork movement Cell. 84:1996;643-650
16. Kornberg A., Baker T.A. DNA Replication. Second Edition:1992;W.H. Freeman and Company, New York
17. Labib K., Tercero J.A., Diffley J.F.X. Uninterrupted MCM2-7 function required for DNA replication fork progression. Science. 288:2000;1643-1647
18. Laskey R.A., Madine M.A. A rotary pump model for helicase function of MCM proteins at a distance from replication forks. EMBO Rep. 22:2003;704-712
19. LeBowitz J.H., McMacken R. The Escherichia coli dnaB replication protein is a DNA helicase. J. Biol. Chem. 261:1986;4738-4748
20. Lee J.-K., Hurwitz J. Isolation and characterization of various complexes of the minichromosome maintenance proteins of Schizosaccharomyces pombe. J. Biol. Chem. 275:2000;18871-18878
21. Lemon K.P., Grossman A.D. Localization of bacterial DNA polymerase. evidence for a factory model of replication Science. 282:1998;1516-1519
22. Li D., Zhao R., Lilyestrom W., Gal D., Zhang R., DeCaprio J.A., Fanning E., Jochimiak A., Szakonyl G., Chen X.S. Structure of the replicative helicase of the oncoprotein SV40 large tumor antigen. Nature. 423:2003;512-518
23. Lloyd R.G., Sharples G.J. Dissociation of synthetic Holliday junctions by E. coli RecG protein. EMBO J. 12:1993;17-22
24. McGlynn P., Lloyd R.G. Action of RuvAB at replication fork structures. J. Biol. Chem. 276:2001;41938-41944
25. Mendez J., Stillman B. Perpetuating the double helix. molecular machines at eukaryotic DNA replication origins Bioessays. 25:2003;1158-1167
26. Parsons C.A., West S.C. Formation of a RuvAB-Holliday junction complex in vitro. J. Mol. Biol. 232:1993;397-405
27. Rajendran S., Jezewska M.J., Bujalowski W. Multiple-step kinetic mechanism of DNA-independent ATP binding and hydrolysis by Escherichia coli replicative helicase DnaB protein. quantitative analysis using the rapid quench-flow method J. Mol. Biol. 303:2000;773-795
28. Sato M., Gotow T., You Z., Komamura-Kohno Y., Uchiyama Y., Yabuta N., Nojima H., Ishimi Y. Electron microscopic observation and single-stranded DNA binding activity of the Mcm4,6,7 complex. J. Mol. Biol. 300:2000;421-431
29. Shin J.H., Jiang Y., Grabowski B., Hurwitz J., Kelman Z. Substrate requirements for duplex DNA translocation by the eukaryal and archaeal minichromosome maintenance helicases. J. Biol. Chem. 278:2003;49053-49062
30. Singleton M.R., Sawaya M.R., Ellenberger T., Wigley D.B. Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides. Cell. 101:2000;589-600
31. Tsaneva I.R., Muller B., West S.C. ATP-dependent branch migration of Holliday junctions promoted by the RuvA and RuvB proteins of E. coli. Cell. 69:1992;1171-1180
32. Tsaneva I.R., Muller B., West S.C. RuvA and RuvB proteins of Escherichia coli exhibit DNA helicase activity in vitro. Proc. Natl. Acad. Sci. USA. 90:1993;1315-1319
33. VanLoock M., Alexandrov A., Yu X., Cozzarelli N., Egelman E. SV40 large T antigen hexamer structure. domain organization and DNA-induced conformational changes Curr. Biol. 12:2002;472-476
34. Wahle E., Lasken R.S., Kornberg A. The dnaB-dnaC replication protein complex of Escherichia coli. II. Role of the complex in mobilizing dnaB functions. J. Biol. Chem. 264:1989;2469-2475
35. West S.C. Processing of recombination intermediates by the RuvABC proteins. Annu. Rev. Genet. 31:1997;213-244
36. Yang S., Yu X., VanLoock M., Jezewska M., Bujalowski W., Egelman E. Flexibility of the rings. structural asymmetry in the DnaB hexameric helicase J. Mol. Biol. 321:2002;839-849
37. You Z., Komamura Y., Ishimi Y. Biochemical analysis of the intrinsic Mcm4-Mcm6-Mcm7 DNA helicase activity. Mol. Cell. Biol. 19:1999;8003-8015
38. Yuzhakov A., Turner J., O'Donnell M. Replisome assembly reveals the basis for asymmetric function in leading and lagging strand replication. Cell. 86:1996;877-886