메뉴 건너뛰기




Volumn 304, Issue 1, 2003, Pages 121-129

Mitochondrial dysfunction is an early manifestation of 1,1-dichloroethylene-induced hepatotoxicity in mice

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ADENOSINE DIPHOSPHATE; ALANINE AMINOTRANSFERASE; CYTOCHROME P450; GLUTAMIC ACID; GLUTATHIONE; SUCCINIC ACID; VINYLIDENE CHLORIDE;

EID: 0037214455     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.041392     Document Type: Article
Times cited : (18)

References (35)
  • 1
    • 0017797324 scopus 로고
    • Optimization of methods for aspartate aminotransferase and alanine aminotransferase
    • Bergmeyer HU, Scheibe P, and Wahlefeld AW (1978) Optimization of methods for aspartate aminotransferase and alanine aminotransferase. Clin Chem 24:58.
    • (1978) Clin Chem , vol.24 , pp. 58
    • Bergmeyer, H.U.1    Scheibe, P.2    Wahlefeld, A.W.3
  • 2
    • 0027241092 scopus 로고
    • Control of the effective P/O ratio of oxidative phosphorylation in liver mitochondria and hepatocytes
    • Brand MD, Harper M, and Taylor HC (1993) Control of the effective P/O ratio of oxidative phosphorylation in liver mitochondria and hepatocytes. Biochem J 291: 739-748.
    • (1993) Biochem J , vol.291 , pp. 739-748
    • Brand, M.D.1    Harper, M.2    Taylor, H.C.3
  • 3
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein using the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein using the principle of protein-dye binding. Anal Biochem 72:248-245.
    • (1976) Anal Biochem , vol.72 , pp. 248-245
    • Bradford, M.M.1
  • 4
    • 0032604278 scopus 로고    scopus 로고
    • Evidence of mitochondrial dysfunction in broilers with pulmonary hypertension syndrome (ascites): Effect of t-butyl hydroperoxide on hepatic mitochondrial function, glutathione and related thiols
    • Cawthon D, McNew R, Beers KW, and Bottje WG (1999) Evidence of mitochondrial dysfunction in broilers with pulmonary hypertension syndrome (ascites): Effect of t-butyl hydroperoxide on hepatic mitochondrial function, glutathione and related thiols. Poultry Sci 78:114-124.
    • (1999) Poultry Sci , vol.78 , pp. 114-124
    • Cawthon, D.1    McNew, R.2    Beers, K.W.3    Bottje, W.G.4
  • 5
    • 0020062177 scopus 로고
    • Histochemical evidence that plasma and mitochondrial membranes are primary foci of hepatocellular injury caused by 1,1-dichloroethylene
    • Chieco P, Moslen MT, and Reynolds ES (1982) Histochemical evidence that plasma and mitochondrial membranes are primary foci of hepatocellular injury caused by 1,1-dichloroethylene. Lab Invest 46:413-421.
    • (1982) Lab Invest , vol.46 , pp. 413-421
    • Chieco, P.1    Moslen, M.T.2    Reynolds, E.S.3
  • 6
    • 0000146185 scopus 로고
    • The occurrence of volatile organics in five drinking water supplies using gas chromatography/mass spectrophotometry
    • Keith LH ed, Ann Arbor Science Publishers, Ann Arbor, MI
    • Coleman WE, Lingg RD, Melton RG, and Kopfler FC (1976) The occurrence of volatile organics in five drinking water supplies using gas chromatography/mass spectrophotometry, in Identification and Analysis of Organic Pollutants in Water (Keith LH ed) pp 305-327, Ann Arbor Science Publishers, Ann Arbor, MI.
    • (1976) Identification and Analysis of Organic Pollutants in Water , pp. 305-327
    • Coleman, W.E.1    Lingg, R.D.2    Melton, R.G.3    Kopfler, F.C.4
  • 8
    • 0021674075 scopus 로고
    • Chlorinated ethylenes: Their metabolism and effect on DNA repair in rat hepatocytes
    • Costa AK and Ivanetich KM (1984) Chlorinated ethylenes: Their metabolism and effect on DNA repair in rat hepatocytes. Carcinogenesis 5:1629-1636.
    • (1984) Carcinogenesis , vol.5 , pp. 1629-1636
    • Costa, A.K.1    Ivanetich, K.M.2
  • 9
    • 0345018815 scopus 로고    scopus 로고
    • N-Acetylcysteine: Pharmacological considerations and experimental and clinical applications
    • Cotgreave IA (1997) N-Acetylcysteine: Pharmacological considerations and experimental and clinical applications. Adv Pharmacol 38:205-227.
    • (1997) Adv Pharmacol , vol.38 , pp. 205-227
    • Cotgreave, I.A.1
  • 10
    • 0022646351 scopus 로고
    • The effect of inhibitors of mitochondrial energy production on hepatic glutathione. UDP-glucuronic acid and adenosine 3′-phosphate-5′-phosphosulfate concentrations
    • Dills RI and Klaassen CD (1986) The effect of inhibitors of mitochondrial energy production on hepatic glutathione, UDP-glucuronic acid and adenosine 3′-phosphate-5′-phosphosulfate concentrations. Drug Metab Dispos 14:190-196.
    • (1986) Drug Metab Dispos , vol.14 , pp. 190-196
    • Dills, R.I.1    Klaassen, C.D.2
  • 11
    • 0027976561 scopus 로고
    • Inhibition of mitochondrial respiration in vivo is an early event in acetaminophen-induced hepatotoxicity
    • Donnelly PJ, Walker RM, and Racz WJ (1993) Inhibition of mitochondrial respiration in vivo is an early event in acetaminophen-induced hepatotoxicity. Arch Toxicol 68:110-118.
    • (1993) Arch Toxicol , vol.68 , pp. 110-118
    • Donnelly, P.J.1    Walker, R.M.2    Racz, W.J.3
  • 12
    • 0028901298 scopus 로고
    • Reaction of glutathione with the electrophilic metabolites of 1,1-dichloroethylene
    • Dowsley TF, Forkert PG, Benesch LA, and Bolton JL (1995) Reaction of glutathione with the electrophilic metabolites of 1,1-dichloroethylene. Chem Biol Interact 95:227-244.
    • (1995) Chem Biol Interact , vol.95 , pp. 227-244
    • Dowsley, T.F.1    Forkert, P.G.2    Benesch, L.A.3    Bolton, J.L.4
  • 13
    • 77957003282 scopus 로고
    • Mitochondrial respiratory control and the polarographic measurement of ADP:O ratios
    • Estabrook RW and Pullman ME eds. Academic Press, New York
    • Estabrook RW (1967) Mitochondrial respiratory control and the polarographic measurement of ADP:O ratios, in Methods in Enzymology (Estabrook RW and Pullman ME eds) pp 41-47, Academic Press, New York.
    • (1967) Methods in Enzymology , pp. 41-47
    • Estabrook, R.W.1
  • 14
    • 0023079953 scopus 로고
    • High-performance liquid chromatography of thiols and disulfides: Dinitrophenol derivatives
    • Fariss MW and Reed DJ (1987) High-performance liquid chromatography of thiols and disulfides: Dinitrophenol derivatives. Methods Enzymol 143:101-109.
    • (1987) Methods Enzymol , vol.143 , pp. 101-109
    • Fariss, M.W.1    Reed, D.J.2
  • 15
    • 0032812927 scopus 로고    scopus 로고
    • In vivo formation and localization of 1,1-dichloroethylene epoxide in murine liver: Identification of its glutathione conjugate 2-S-glutathionyl acetate
    • Forkert (1999) In vivo formation and localization of 1,1-dichloroethylene epoxide in murine liver: Identification of its glutathione conjugate 2-S-glutathionyl acetate. J Pharmacol Exp Ther 290:1299-1306.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 1299-1306
    • Forkert1
  • 16
    • 0025755301 scopus 로고
    • 1,1-Dichloroethylene elicits dose-dependent alterations in covalent binding and glutathione in murine liver
    • Forkert PG and Moussa M (1991) 1,1-Dichloroethylene elicits dose-dependent alterations in covalent binding and glutathione in murine liver. Drug Metab Dispos 19:580-586.
    • (1991) Drug Metab Dispos , vol.19 , pp. 580-586
    • Forkert, P.G.1    Moussa, M.2
  • 17
    • 0023205998 scopus 로고
    • Metabolic activation of 1,1-dichloroethylene by mouse lung and liver microsomes
    • Forkert PG, Hofley M, and Racz WJ (1987) Metabolic activation of 1,1-dichloroethylene by mouse lung and liver microsomes. Can J Physiol Pharmacol 65:1496-1499.
    • (1987) Can J Physiol Pharmacol , vol.65 , pp. 1496-1499
    • Forkert, P.G.1    Hofley, M.2    Racz, W.J.3
  • 18
    • 0022608880 scopus 로고
    • Pulmonary toxicity of 1,1-dichloroethylene: Correlation of early changes with covalent binding
    • Forkert PG, Stringer V, and Troughton KM (1986) Pulmonary toxicity of 1,1-dichloroethylene: Correlation of early changes with covalent binding. Can J Physiol Pharmacol 64:112-121.
    • (1986) Can J Physiol Pharmacol , vol.64 , pp. 112-121
    • Forkert, P.G.1    Stringer, V.2    Troughton, K.M.3
  • 19
    • 0021891869 scopus 로고
    • The mitochondrial electron transport and oxidative phosphorylation system
    • Hatefi Y (1985) The mitochondrial electron transport and oxidative phosphorylation system. Annu Rev Biochem 54:1015.
    • (1985) Annu Rev Biochem , vol.54 , pp. 1015
    • Hatefi, Y.1
  • 20
    • 0017640153 scopus 로고
    • Effect of 1,1-dichloroethylene exposure on hepatic mitochondria
    • Jaeger RJ (1977) Effect of 1,1-dichloroethylene exposure on hepatic mitochondria. Res Commun Chem Pathol Pharmacol 18:83-94.
    • (1977) Res Commun Chem Pathol Pharmacol , vol.18 , pp. 83-94
    • Jaeger, R.J.1
  • 21
    • 0016367032 scopus 로고
    • Effect of 18 hr fast and glutathione depletion on 1,1-dichloroethylene-induced hepatotoxicity and lethality in rats
    • Jaeger RJ, Conolly RB, and Murphy SD (1974) Effect of 18 hr fast and glutathione depletion on 1,1-dichloroethylene-induced hepatotoxicity and lethality in rats. Exp Mol Pathol 20:187-198.
    • (1974) Exp Mol Pathol , vol.20 , pp. 187-198
    • Jaeger, R.J.1    Conolly, R.B.2    Murphy, S.D.3
  • 22
    • 77957010110 scopus 로고
    • Isolation of liver and kidney mitochondria
    • Johnson D and Lardy H (1967) Isolation of liver and kidney mitochondria. Methods Enzymol 10:94-96.
    • (1967) Methods Enzymol , vol.10 , pp. 94-96
    • Johnson, D.1    Lardy, H.2
  • 23
    • 77957187616 scopus 로고
    • Effects of 1,1-dichloroethylene and of some of its metabolites on the functional viability of mouse hepatocytes
    • Kainz A, Cross H, Freeman S, Gescher A, and Chipman JK (1993) Effects of 1,1-dichloroethylene and of some of its metabolites on the functional viability of mouse hepatocytes. Fundam Appl Toxicol 21:140-148.
    • (1993) Fundam Appl Toxicol , vol.21 , pp. 140-148
    • Kainz, A.1    Cross, H.2    Freeman, S.3    Gescher, A.4    Chipman, J.K.5
  • 24
    • 0022549348 scopus 로고
    • Early effects of 1,1-dichloroethylene on canalicular and plasma membranes: Ultrastructure and stereology
    • Kanz MF and Reynolds ES (1986) Early effects of 1,1-dichloroethylene on canalicular and plasma membranes: Ultrastructure and stereology. Exp Mol Pathol 44:93-110.
    • (1986) Exp Mol Pathol , vol.44 , pp. 93-110
    • Kanz, M.F.1    Reynolds, E.S.2
  • 25
    • 0029166099 scopus 로고
    • Glutathione-dependent metabolism of trichloroethylene in isolated liver and kidney cells of rats and its role in mitochondrial and cellular toxicity
    • Lash LH, Xu Y, Elfarra AA, Duescher RJ, and Parker JC (1995) Glutathione-dependent metabolism of trichloroethylene in isolated liver and kidney cells of rats and its role in mitochondrial and cellular toxicity. Drug Metab Dispos 23:846-853.
    • (1995) Drug Metab Dispos , vol.23 , pp. 846-853
    • Lash, L.H.1    Xu, Y.2    Elfarra, A.A.3    Duescher, R.J.4    Parker, J.C.5
  • 26
    • 0028239623 scopus 로고
    • In vitro biotransformation of 1,1-dichloroethylene by hepatic cytochrome P-450 2E1 in mice
    • Lee RP and Forkert PG (1994) In vitro biotransformation of 1,1-dichloroethylene by hepatic cytochrome P-450 2E1 in mice. J Pharmacol Exp Ther 270:371-376.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 371-376
    • Lee, R.P.1    Forkert, P.G.2
  • 27
    • 0023911064 scopus 로고
    • S-(2-Chloroacetyl)glutathione, a reactive glutathione thiol ester and a putative metabolite of 1,1-dichloroethylene
    • Liebler DC, Latwesen DG, and Reeder TC (1988) S-(2-Chloroacetyl)glutathione, a reactive glutathione thiol ester and a putative metabolite of 1,1-dichloroethylene. Biochemistry 27:3652-3657.
    • (1988) Biochemistry , vol.27 , pp. 3652-3657
    • Liebler, D.C.1    Latwesen, D.G.2    Reeder, T.C.3
  • 28
    • 0021934593 scopus 로고
    • Formation of glutathione conjugates by reactive metabolites of vinylidene chloride in microsomes and isolated hepatocytes
    • Liebler DC, Meredith MJ, and Guengerich FP (1985) Formation of glutathione conjugates by reactive metabolites of vinylidene chloride in microsomes and isolated hepatocytes. Cancer Res 45:186-193.
    • (1985) Cancer Res , vol.45 , pp. 186-193
    • Liebler, D.C.1    Meredith, M.J.2    Guengerich, F.P.3
  • 29
    • 0012197804 scopus 로고    scopus 로고
    • The respiratory chain and oxidative phosphorylation
    • Barnes DA, Ransom J and Roche J eds. Appleton and Lange, Stamford, CT
    • Murray RK, Granner DK, Mayes PA, and Rodwell VW (2000) The respiratory chain and oxidative phosphorylation, in Harper's Biochemistry (Barnes DA, Ransom J and Roche J eds) pp 137-148, Appleton and Lange, Stamford, CT.
    • (2000) Harper's Biochemistry , pp. 137-148
    • Murray, R.K.1    Granner, D.K.2    Mayes, P.A.3    Rodwell, V.W.4
  • 30
    • 0022505322 scopus 로고
    • 14C]1,1-dichloroethylene in mice: In vivo and in vitro studies
    • 14C]1,1-dichloroethylene in mice: In vivo and in vitro studies. Adv Exp Med Biol 197:903-910.
    • (1986) Adv Exp Med Biol , vol.197 , pp. 903-910
    • Okine, L.K.1    Gram, T.E.2
  • 31
    • 0022378512 scopus 로고
    • Studies on the distribution and covalent binding of 1,1-dichloroethylene in the mouse. Effect of various pretreatments on covalent binding in vivo
    • Okine LK, Goochee JM, and Gram TE (1985) Studies on the distribution and covalent binding of 1,1-dichloroethylene in the mouse. Effect of various pretreatments on covalent binding in vivo. Biochem Pharmacol 34:4051-4057.
    • (1985) Biochem Pharmacol , vol.34 , pp. 4051-4057
    • Okine, L.K.1    Goochee, J.M.2    Gram, T.E.3
  • 32
    • 0017621629 scopus 로고
    • Damage to hepatic cellular membranes by chlorinated olefins with emphasis on synergism and antagonism
    • Reynolds ES and Moslen MT (1977) Damage to hepatic cellular membranes by chlorinated olefins with emphasis on synergism and antagonism. Environ Health Perspect 21:137-147.
    • (1977) Environ Health Perspect , vol.21 , pp. 137-147
    • Reynolds, E.S.1    Moslen, M.T.2
  • 33
    • 0016776435 scopus 로고
    • Hepatotoxicity of vinyl chloride and 1,1-dichloroethylene. Role of mixed function oxidase system
    • Reynolds ES, Moslen MT, Szabo S, Jaeger RJ, and Murphy SD (1975) Hepatotoxicity of vinyl chloride and 1,1-dichloroethylene. Role of mixed function oxidase system. Am J Pathol 81:219-236.
    • (1975) Am J Pathol , vol.81 , pp. 219-236
    • Reynolds, E.S.1    Moslen, M.T.2    Szabo, S.3    Jaeger, R.J.4    Murphy, S.D.5
  • 34
    • 0029132869 scopus 로고
    • In Situ Bioremediation of Chlorinated Solvents
    • Semprini L (1995) In Situ Bioremediation of Chlorinated Solvents. Environ Health Perspect 103:101-105.
    • (1995) Environ Health Perspect , vol.103 , pp. 101-105
    • Semprini, L.1
  • 35
    • 0026778948 scopus 로고
    • Dietary protein level alters oxidative phosphorylation in heart and liver mitochondria of chicks
    • Toyomizu M, Kirihara D, Tanaka M, Hayashi K, and Tomita Y (1992) Dietary protein level alters oxidative phosphorylation in heart and liver mitochondria of chicks. Br J Nutr 68:89-99.
    • (1992) Br J Nutr , vol.68 , pp. 89-99
    • Toyomizu, M.1    Kirihara, D.2    Tanaka, M.3    Hayashi, K.4    Tomita, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.