-
1
-
-
11944260623
-
Molecular cloning of a cDNA encoding interleukin 11, a novel stromal cell-derived lymphopoietic and hematopoietic cytokine
-
S. R. Paul, F. Bennett, J. A. Calvetti, K. Kelleher, C. R. Wood, R. M. O'Hara, Jr., A. C. Lear, B. Sibley, S. C. Clark and Y. C. Yang, Molecular cloning of a cDNA encoding interleukin 11, a novel stromal cell-derived lymphopoietic and hematopoietic cytokine. Proc. Natl. Acad. Sci. USA 87, 7512-7516 (1990).
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 7512-7516
-
-
Paul, S.R.1
Bennett, F.2
Calvetti, J.A.3
Kelleher, K.4
Wood, C.R.5
O'Hara Jr., R.M.6
Lear, A.C.7
Sibley, B.8
Clark, S.C.9
Yang, Y.C.10
-
3
-
-
0030828578
-
Recombinant human interleukin-11 directly promotes megakaryocytopoiesis in vitro
-
N. S. Weich, A. Wang, M. Fitzgerald, T. Y. Neben, D. Donaldson, J. Calvetti, J. Yetz-Aldape, R. M. Leven and K. J. Turner, Recombinant human interleukin-11 directly promotes megakaryocytopoiesis in vitro. Blood 90, 3893-3902 (1997).
-
(1997)
Blood
, vol.90
, pp. 3893-3902
-
-
Weich, N.S.1
Wang, A.2
Fitzgerald, M.3
Neben, T.Y.4
Donaldson, D.5
Calvetti, J.6
Yetz-Aldape, J.7
Leven, R.M.8
Turner, K.J.9
-
4
-
-
0027459101
-
In vivo effects of recombinant human interleukin-11 on myelopoiesis in mice
-
G. Hangoc, T. Yin, S. Cooper, P. Schendel, Y. C. Yang and H. E. Broxmeyer, In vivo effects of recombinant human interleukin-11 on myelopoiesis in mice. Blood 81, 965-972 (1993).
-
(1993)
Blood
, vol.81
, pp. 965-972
-
-
Hangoc, G.1
Yin, T.2
Cooper, S.3
Schendel, P.4
Yang, Y.C.5
Broxmeyer, H.E.6
-
5
-
-
0027397921
-
Recombinant human interleukin-11 stimulates megakaryocytopoiesis and increases peripheral platelets in normal and splenectomized mice
-
T. Y. Nenben, J. Leobelenz, L. Hayes, K. McCarthy, J. Stoudemire, R. Schaub and S. J. Goldman, Recombinant human interleukin-11 stimulates megakaryocytopoiesis and increases peripheral platelets in normal and splenectomized mice. Blood 81, 901-908 (1993).
-
(1993)
Blood
, vol.81
, pp. 901-908
-
-
Nenben, T.Y.1
Leobelenz, J.2
Hayes, L.3
McCarthy, K.4
Stoudemire, J.5
Schaub, R.6
Goldman, S.J.7
-
6
-
-
0029864394
-
Constant subcutaneous infusion of rhIL-11 in mice: Efficient delivery enhances biological activity
-
J. P. Leonard, T. Y. Neben, M. K. Kozitza, C. M. Quinto and S. J. Goldman, Constant subcutaneous infusion of rhIL-11 in mice: Efficient delivery enhances biological activity. Exp. Hematol. 24, 270-276 (1996).
-
(1996)
Exp. Hematol.
, vol.24
, pp. 270-276
-
-
Leonard, J.P.1
Neben, T.Y.2
Kozitza, M.K.3
Quinto, C.M.4
Goldman, S.J.5
-
7
-
-
0028044048
-
The combined effects of interleukin-11, stem cell factor, and granulocyte colony-stimulating factor on newborn rat hematopoiesis: Significant enhancement of the absolute neutrophil count
-
M. S. Cairo, J. M. Plunkett, P. Schendel and C. van de Yen, The combined effects of interleukin-11, stem cell factor, and granulocyte colony-stimulating factor on newborn rat hematopoiesis: Significant enhancement of the absolute neutrophil count. Exp. Hematol. 22, 1118-1123 (1994).
-
(1994)
Exp. Hematol.
, vol.22
, pp. 1118-1123
-
-
Cairo, M.S.1
Plunkett, J.M.2
Schendel, P.3
Van De Yen, C.4
-
8
-
-
0027276040
-
Effect of interleukin-11 with and without granulocyte colony-stimulating factor on in vivo neonatal rat hematopoiesis: Induction of neonatal thrombocytosis by interleukin-11 and synergistic enhancement of neutrophilia by interleukin-11 + granulocyte colony-stimulating factor
-
M. S. Cairo, J. M. Plunkett, A. Nguyen, P. Schendel and C. van de Ven, Effect of interleukin-11 with and without granulocyte colony-stimulating factor on in vivo neonatal rat hematopoiesis: induction of neonatal thrombocytosis by interleukin-11 and synergistic enhancement of neutrophilia by interleukin-11 + granulocyte colony-stimulating factor. Pediatr. Res. 34, 56-61 (1993).
-
(1993)
Pediatr. Res.
, vol.34
, pp. 56-61
-
-
Cairo, M.S.1
Plunkett, J.M.2
Nguyen, A.3
Schendel, P.4
Van De Ven, C.5
-
9
-
-
0029084751
-
In vivo effects of interleukin-11 and stem cell factor in combination with erythropoietin in the regulation of erythropoiesis
-
G. De Haan, B. Dontje, C. Engel, M. Loeffler and W. Nijhof, In vivo effects of interleukin-11 and stem cell factor in combination with erythropoietin in the regulation of erythropoiesis. Br. J. Haematol. 90, 783-790 (1995).
-
(1995)
Br. J. Haematol.
, vol.90
, pp. 783-790
-
-
De Haan, G.1
Dontje, B.2
Engel, C.3
Loeffler, M.4
Nijhof, W.5
-
10
-
-
0027390268
-
Effects of recombinant human interleukin-11 on hematopoietic reconstitution in transplant mice: Acceleration of recovery of peripheral blood neutrophils and platelets
-
X. X. Du, T. Neben, S. Goldman and D. A. Williams, Effects of recombinant human interleukin-11 on hematopoietic reconstitution in transplant mice: Acceleration of recovery of peripheral blood neutrophils and platelets. Blood 81, 27-34 (1993).
-
(1993)
Blood
, vol.81
, pp. 27-34
-
-
Du, X.X.1
Neben, T.2
Goldman, S.3
Williams, D.A.4
-
11
-
-
0028295738
-
Interleukin-11 expression in donor bone marrow cells improves hematological reconstitution in lethally irradiated recipient mice
-
S. R. Paul, L. L. Hayes, R. Palmer, G. E. Morris, T. Y. Neben, J. Loebelenz, G. Pedneault, J. Brooks, I. Blue and C. R. Wood, Interleukin-11 expression in donor bone marrow cells improves hematological reconstitution in lethally irradiated recipient mice. Exp. Hematol. 22, 295-301 (1994).
-
(1994)
Exp. Hematol.
, vol.22
, pp. 295-301
-
-
Paul, S.R.1
Hayes, L.L.2
Palmer, R.3
Morris, G.E.4
Neben, T.Y.5
Loebelenz, J.6
Pedneault, G.7
Brooks, J.8
Blue, I.9
Wood, C.R.10
-
12
-
-
0029987383
-
Combined effects of interleukin-3 and interleukin-11 on hematopoiesis in irradiated mice
-
M. C. Galmiche, C. A. Vogel, A. B. Delaloye, P. M. Schmidt, F. Healy, J. P. Mach and F. Buchegger, Combined effects of interleukin-3 and interleukin-11 on hematopoiesis in irradiated mice. Exp. Hematol. 24, 1298-1306 (1996).
-
(1996)
Exp. Hematol.
, vol.24
, pp. 1298-1306
-
-
Galmiche, M.C.1
Vogel, C.A.2
Delaloye, A.B.3
Schmidt, P.M.4
Healy, F.5
Mach, J.P.6
Buchegger, F.7
-
13
-
-
0029801484
-
IL-11 synergizes with IL-3 in promoting the recovery of the immune system after irradiation
-
D. Frasca, C. Pioli, F. Guidi, S. Pucci, M. Arbitrio, G. Leter and G. Doria, IL-11 synergizes with IL-3 in promoting the recovery of the immune system after irradiation. Int. Immumol. 8, 1651-1657 (1996).
-
(1996)
Int. Immumol.
, vol.8
, pp. 1651-1657
-
-
Frasca, D.1
Pioli, C.2
Guidi, F.3
Pucci, S.4
Arbitrio, M.5
Leter, G.6
Doria, G.7
-
14
-
-
0030611033
-
Use of hematopoietic cytokines to accelerate the recovery of the immune system in irradiated mice
-
D. Frasca, F. Guidi, M. Arbitrio, C. Pioli, G. Leter, M. Spano and G. Doria, Use of hematopoietic cytokines to accelerate the recovery of the immune system in irradiated mice. Exp. Hematol. 25, 1167-1171 (1997).
-
(1997)
Exp. Hematol.
, vol.25
, pp. 1167-1171
-
-
Frasca, D.1
Guidi, F.2
Arbitrio, M.3
Pioli, C.4
Leter, G.5
Spano, M.6
Doria, G.7
-
15
-
-
0029070429
-
Effects of rhIL-11 on normal dogs and after sublethal radiation
-
R. A. Nash, K. Seidel, R. Storb, S. Slichter, F. G. Schuening, F. R. Appelbaum, A. B. Becker, L. Bolles, H. J. Deeg and S. A. Burstein, Effects of rhIL-11 on normal dogs and after sublethal radiation. Exp. Hematol. 23, 389-396 (1995).
-
(1995)
Exp. Hematol.
, vol.23
, pp. 389-396
-
-
Nash, R.A.1
Seidel, K.2
Storb, R.3
Slichter, S.4
Schuening, F.G.5
Appelbaum, F.R.6
Becker, A.B.7
Bolles, L.8
Deeg, H.J.9
Burstein, S.A.10
-
16
-
-
0029861581
-
Effects of recombinant human interleukin-11 (Neumega rhIL-11 growth factor) on megakaryocytopoiesis in human bone marrow
-
A. Orazi, R. J. Cooper, J. Tong, M. S. Gordon, L. Battiato, G. W. Sledge, Jr., J. A. Kaye, M. Kahsai and R. Hoffman, Effects of recombinant human interleukin-11 (Neumega rhIL-11 growth factor) on megakaryocytopoiesis in human bone marrow. Exp. Hematol. 24, 1289-1297 (1996).
-
(1996)
Exp. Hematol.
, vol.24
, pp. 1289-1297
-
-
Orazi, A.1
Cooper, R.J.2
Tong, J.3
Gordon, M.S.4
Battiato, L.5
Sledge Jr., G.W.6
Kaye, J.A.7
Kahsai, M.8
Hoffman, R.9
-
17
-
-
0030666621
-
Randomized placebo-controlled study of recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in patients with breast cancer receiving dose-intensive cyclophosphamide and doxorubicin
-
C. Issacs, N. J. Robert, F. A. Bailey, M. W. Schuster, B. Overmoyer, M. Graham, B. Cai, K. J. Beach, J. W. Loewy and J. A. Kaye, Randomized placebo-controlled study of recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in patients with breast cancer receiving dose-intensive cyclophosphamide and doxorubicin. J. Clin. Oncol. 15, 3368-3377 (1997).
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 3368-3377
-
-
Issacs, C.1
Robert, N.J.2
Bailey, F.A.3
Schuster, M.W.4
Overmoyer, B.5
Graham, M.6
Cai, B.7
Beach, K.J.8
Loewy, J.W.9
Kaye, J.A.10
-
18
-
-
15844395460
-
A phase I trial of recombinant human interleukin-11 (Neumega rhIL-11 growth factor) in women with breast cancer receiving chemotherapy
-
M. S. Gordon, W. J. McCaskill-Stevens, L. A. Battiato, J. Leow, D. Loesch, E. Breeden, R. Hoffman, K. J. Beach, B. Kuca and G. W. Sledge, Jr., A phase I trial of recombinant human interleukin-11 (Neumega rhIL-11 growth factor) in women with breast cancer receiving chemotherapy. Blood 87, 3615-3624 (1996).
-
(1996)
Blood
, vol.87
, pp. 3615-3624
-
-
Gordon, M.S.1
McCaskill-Stevens, W.J.2
Battiato, L.A.3
Leow, J.4
Loesch, D.5
Breeden, E.6
Hoffman, R.7
Beach, K.J.8
Kuca, B.9
Sledge Jr., G.W.10
-
19
-
-
9244234420
-
A randomized placebo-controlled trial of recombinant human interleukin-11 in cancer patients with severe thrombocytopenia due to chemotherapy
-
I. Tepler, L. Elias, J. W. Smith, 2nd, M. Hussein, G. Rosen, A. Y. Chang, J. O. Moore, M. S. Gordon, B. Kuca and J. A. Kaye, A randomized placebo-controlled trial of recombinant human interleukin-11 in cancer patients with severe thrombocytopenia due to chemotherapy. Blood 87, 3607-3614 (1996).
-
(1996)
Blood
, vol.87
, pp. 3607-3614
-
-
Tepler, I.1
Elias, L.2
Smith II, J.W.3
Hussein, M.4
Rosen, G.5
Chang, A.Y.6
Moore, J.O.7
Gordon, M.S.8
Kuca, B.9
Kaye, J.A.10
-
20
-
-
0029778822
-
Thrombopoietic activity of recombinant human interleukin 11 (rHuIL-11) in normal and myelosuppressed nonhuman primates
-
F. J. Schlerman, A. G. Bree, M. D. Kaviani, S. L. Nagle, L. H. Donnelly, L. E. Mason, R. G. Schaub, S. A. Grupp and S. J. Goldman, Thrombopoietic activity of recombinant human interleukin 11 (rHuIL-11) in normal and myelosuppressed nonhuman primates. Stem Cells 14, 517-532 (1996).
-
(1996)
Stem Cells
, vol.14
, pp. 517-532
-
-
Schlerman, F.J.1
Bree, A.G.2
Kaviani, M.D.3
Nagle, S.L.4
Donnelly, L.H.5
Mason, L.E.6
Schaub, R.G.7
Grupp, S.A.8
Goldman, S.J.9
-
21
-
-
0026630530
-
Synergistic effects of interleukin 3 and interleukin 11 on murine megakaryopoiesis in serum-free culture
-
Y. Yonemura, M. Kawakita, T. Masuda, K. Fujimoto, K. Kato and K. Takatsuki, Synergistic effects of interleukin 3 and interleukin 11 on murine megakaryopoiesis in serum-free culture. Exp. Hematol. 20, 1011-1016 (1992).
-
(1992)
Exp. Hematol.
, vol.20
, pp. 1011-1016
-
-
Yonemura, Y.1
Kawakita, M.2
Masuda, T.3
Fujimoto, K.4
Kato, K.5
Takatsuki, K.6
-
22
-
-
0028350885
-
Synergistic effects of interleukin-11 with other growth factors on the expansion of murine hematopoietic progenitors and maintenance of stem cells in liquid culture
-
S. Neben, D. Donaldson, C. Sieff, P. Mauch, D. Bodine, J. Ferrara, J. Yetz-Aldape and K. Turner, Synergistic effects of interleukin-11 with other growth factors on the expansion of murine hematopoietic progenitors and maintenance of stem cells in liquid culture. Exp. Hematol. 22, 353-359 (1994).
-
(1994)
Exp. Hematol.
, vol.22
, pp. 353-359
-
-
Neben, S.1
Donaldson, D.2
Sieff, C.3
Mauch, P.4
Bodine, D.5
Ferrara, J.6
Yetz-Aldape, J.7
Turner, K.8
-
23
-
-
0033663586
-
Mechanism and amelioration of recombinant human interleukin-11 (rhIL-11)-induced anemia in healthy subjects
-
K. H. Dykstra, H. Rogge, A. Stone, J. Loewy, J. C. Keith and U. S. Schwertschlag, Mechanism and amelioration of recombinant human interleukin-11 (rhIL-11)-induced anemia in healthy subjects. J. Clin. Pharmacol. 40, 880-888 (2000).
-
(2000)
J. Clin. Pharmacol.
, vol.40
, pp. 880-888
-
-
Dykstra, K.H.1
Rogge, H.2
Stone, A.3
Loewy, J.4
Keith, J.C.5
Schwertschlag, U.S.6
-
24
-
-
0034650985
-
Recombinant human interleukin-11 synergizes with steel factor and interleukin-3 to promote directly the early stages of murine megakaryocyte development in vitro
-
N. S. Weich, M. Fitzgerald, A. Wang, J. Calvetti, J. Yetz-Aldape, S. Neben and K. J. Turner, Recombinant human interleukin-11 synergizes with steel factor and interleukin-3 to promote directly the early stages of murine megakaryocyte development in vitro. Blood 95, 503-509 (2000).
-
(2000)
Blood
, vol.95
, pp. 503-509
-
-
Weich, N.S.1
Fitzgerald, M.2
Wang, A.3
Calvetti, J.4
Yetz-Aldape, J.5
Neben, S.6
Turner, K.J.7
|