Genetic and expression profiles of cerebellar liponeurocytomas

Brain Pathology

Volumn 14, Issue 3, 2004, Pages 281-289

  Hostmann, Sonja ^a   Perry, Arie ^b   Reifenberger, Guido ^c   Giangaspero, Felice ^d   Huang, Herve ^a   Hara, Akira ^a   Masuoka, Jun ^a   Rainov, Nikolai G ^e   Bergmann, Markus ^f   Heppner, Frank L ^g   Brandner, Sebastian ^h   Chimelli, Leila ⁱ   Montagna, Nádia ^j   Jackson, Thad ^k   Davis, Daron G ^l   Markesbery, William R ^l   Ellison, David W ^m   Weller, Roy O ⁿ   Taddei, Gian L ^o   Conti, Renato ^p   Del Bigio, Marc R ^q   González Cámpora, Ricardo ^r   Radhakrishnan, V V ^s   Söylemezoglu, Figen ^t   Uro Coste, Emmanuelle ^u   Qian, Jiang ^v   Kleihues, Paul ^g   Ohgaki, Hiroko ^a   more..

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HEINRICH HEINE UNIVERSITY   (Germany)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e UNIVERSITY OF LIVERPOOL   (United Kingdom)

^f Institute of Clinical Neuropathology   (Germany)

^g UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^h UNIVERSITY COLLEGE LONDON   (United Kingdom)

ⁱ FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^j STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^k UNIVERSITY OF KENTUCKY   (United States)

^l UNIVERSITY OF KENTUCKY   (United States)

^m NEWCASTLE UNIVERSITY   (United Kingdom)

ⁿ UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^o UNIVERSITY OF FLORENCE   (Italy)

^p UNIVERSITY OF FLORENCE   (Italy)

^q UNIVERSITY OF MANITOBA   (Canada)

^r HOSPITAL UNIVERSITARIO VIRGEN MACARENA   (Spain)

^s SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY   (India)

^t HACETTEPE UNIVERSITY   (Turkey)

^u CHU RANGUEIL   (France)

^v ALBANY MEDICAL COLLEGE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; AXIN; BETA CATENIN; CELL CYCLE PROTEIN; COMPLEMENTARY DNA; DNA TOPOISOMERASE; GENE PRODUCT; KI 67 ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P53; PROTEIN RAD1; PROTEIN RAD21; UNCLASSIFIED DRUG;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BRAIN FOURTH VENTRICLE; CANCER RADIOTHERAPY; CEREBELLAR LIPONEUROCYTOMA; CEREBELLUM TUMOR; CHROMOSOME 17Q; CLINICAL ARTICLE; CLUSTER ANALYSIS; DNA SEQUENCE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLOW UP; GENE EXPRESSION PROFILING; HUMAN; HUMAN TISSUE; ISOCHROMOSOME; LIPOMA; MALE; MEDULLOBLASTOMA; MISSENSE MUTATION; NEUROEPITHELIOMA; NEUROSURGERY; NUCLEOTIDE SEQUENCE; PROGNOSIS; SINGLE STRAND CONFORMATION POLYMORPHISM;

EID: 4143083585     PISSN: 10156305     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2004.tb00065.x     Document Type: Article

References (63)

1. Adesina AM, Nalbantoglu J, Cavenee WK (1994) p53 gene mutation and mdm2 gene amplification are uncommon in medulloblastoma. Cancer Res 54:5649-5651.
2. Akhaddar A, Zrara I, Gazzaz M, El Moustarchid B, Benomar S, Boucetta M (2003) Cerebellar liponeurocytoma (lipomatous medulloblastoma). J Neuroradiol 30:121-126.
3. Alkadhi H, Keller M, Brandner S, Yonekawa Y, Kollias SS (2001) Neuroimaging of cerebellar liponeurocytoma. Case report. J Neurosurg 95: 324-331.
4. Alleyne CH, Jr., Hunter S, Olson JJ, Barrow DL (1998) Lipomatous glioneurocytoma of the posterior fossa with divergent differentiation:case report. Neurosurgery 42:639-643.
5. Badiali M, Iolascon A, Loda M, Scheithauer BW, Basso G, Trentini GP, Giangaspero F (1993) p53 gene mutations in medulloblastoma. Immunohistochemistry, gel shift analysis, and sequencing. Diagn Mol Pathol 2:23-28.
6. Baeza N, Masuoka J, Kleihues P, Ohgaki H (2003) AXIN1 mutations but not deletions in cerebellar medulloblastomas. Oncogene 22:632-636.
7. Bailey SM, Cornforth MN, Kurimasa A, Chen DJ, Goodwin EH (2001) Strand-specific postreplicative processing of mammalian telomeres. Science 293:2462-2465.
8. Bechtel JT, Patton JM, Takei Y (1978) Mixed mesenchymal and neuroectodermal tumor of the cerebellum. Acta Neuropathol (Berl) 41:261-263.
9. Biegel JA, Rorke LB, Janss AJ, Sutton LN, Parmiter AH (1995) Isochromosome 17q demonstrated by interphase fluorescence in situ hybridization in primitive neuroectodermal tumors of the central nervous system. Genes Chromosomes Cancer 14:85-96.
10. Budka H, Chimelli L (1994) Lipomatous medulloblastoma in adults: a new tumor type with possible favorable prognosis. Hum Pathol 25: 730-731.
11. Buhren J, Christoph AH, Buslei R, Albrecht S, Wiestler OD, Pietsch T (2000) Expression of the neurotrophin receptor p75NTR in medulloblastomas is correlated with distinct histologiclal and clinical features:evidence for a medulloblastoma subtype derived from the external granule cell layer. J Neuropathol Exp Neurol 59:229-240.
12. Burnett ME, White EC, Sih S, von Haken MS, Cogen PH (1997) Chromosome arm 17p deletion analysis reveals molecular genetic heterogeneity in supratentorial and infratentorial primitive neuroectodermal tumors of the central nervous system. Cancer Genet Cytogenet 97:25-31.
13. Cacciola F, Conti R, Taddei GL, Buccoliero AM, Di Lorenzo N (2002) Cerebellar liponeurocytoma. Case report with considerations on prognosis and management. Acta Neurochir (Wien) 144: 829-833.
14. Chen F, Kamradt M, Mulcahy M, Byun Y, Xu H, McKay MJ, Cryns VL (2002) Caspase proteolysis of the cohesin component RAD21 promotes apoptosis. J Biol Chem 277:16775-16781.
15. Chimelli L, Hahn MD, Budka H (1991) Lipomatous differentiation in a medulloblastoma. Acta Neuropathol (Berl) 81:471-473.
16. Cogen PH, Daneshvar L, Metzger AK, Duyk G, Edwards MS, Sheffield VC (1992) Involvement of multiple chromosome 17p loci in medulloblastoma tumorigenesis. Am J Hum Genet 50:584-589.
17. Dahmane N, Altaba A (1999) Sonic hedgehog regulates the growth and patterning of the cerebellum. Development 126:3089-3100.
18. Dahmen RR Koch A, Denkhaus D, Tonn JC, Sörensen N, Berthold F, Behrens J, Birchmeier W, Wiestler OD, Pietsch T (2001) Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas. Cancer Res 61: 7039-7043.
19. Davis DG, Wilson D, Schmitz M, Markesbery WR (1993) Lipidized medulloblastoma in adults. Hum Pathol 24:990-995.
20. De La Coste A, Romagnolo B, Billuart P, Renard CA, Buendia MA, Soubrane O, Fabre M, Chelly J, Beldjord C, Kahn A, Perret C (1998) Somatic mutations of the b-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc Natl Acad Sci U S A 95:8847-8851.
21. DeChiara C, Borghese A, Fiorillo A, Genesio R, Conti A, D'Amore R, Pettinato G, Varone A, Maggi G (2002) Cytogenetic evaluation of isochromosome 17q in posterior fossa tumors of children and correlation with clinical outcome in medulloblastoma. Detection of a novel chromosomal abnormality. Childs Nerv Syst 18:380-384.
22. Dong J, Gailani MR, Pomeroy SL, Reardon D, Bale AE (2000) Identification of PATCHED mutations in medulloblastomas by direct sequencing. Hum Mutat 16:89-90.
23. Eberhart CG, Tihan T, Burger PC (2000) Nuclear localization and mutation of b-catenin in medulloblastomas. J Neuropathol Exp Neurol 59:333-337.
24. Ellison DW, Zygmunt SC, Weller RO (1993) Neurocytoma/lipoma (neurolipocytoma) of the cerebellum. Neuropathol Appl Neurobiol 19: 95-98.
25. Fung KM, Fang W, Norton RE, Torres N, Chu A, Langford LA (2003) Cerebellar central liponeurocytoma. Ultrastruct Pathol 27:109-114.
26. Giangaspero F, Cenacchi G, Roncaroli F, Rigobello L, Manetto V, Gambacorta M, Allegranza A (1996) Medullocytoma (lipidized medulloblastoma). A cerebellar neoplasm of adults with favorable prognosis. Am J Surg Pathol 20:656-664.
27. Giordana MT, Schiffer P, Boghi A, Buoncristiani P, Benech F (2000) Medulloblastoma with lipidized cells versus lipomatous medulloblastoma. Clin Neuropathol 19:273-277.
28. Gonzalez-Campora R, Weller RO (199B) Lipidized mature neuroectodermal tumor of the cerebellum with myoid differentiation. Neuropathol Appl Neurobiol 24:397-402.
29. Hakimi MA, Bochar DA, Schmiesing JA, Dong Y, Barak OG, Speicher DW, Yokomori K, Shiekhattar R (2002) A chromatin remodelling complex that loads cohesin onto human chromosomes. Nature 418:994-998.
30. Huang H, Colella S, Kurrer M, Yonekawa Y, Kleihues P, Ohgaki H (2000) Gene expression profiling of low-grade diffuse astrocytomas by cDNA arrays. Cancer Res 60:6868-6874.
31. Huang H, Mahler-Araujo BM, Sankila A, Chimelli L, Yonekawa Y, Kleihues P, Ohgaki H (2000) APC mutations in sporadic medulloblastomas. Am J Pathol 156:433-437.
32. Jackson TR, Regine WF, Wilson D, Davis DG (2001) Cerebellar liponeurocytoma. Case report and review of the literature. J Neurosurg 95: 700-703.
33. Jenkinson MD, Bosma JJD, Du Plessis D, Ohgaki H, Kleihues P, Warnke P, Rainov NG (2003) Cerebellar liponeurocytoma with an unusually aggressive clinical course. Neurosurgery 53:1425-1427.
34. Kleihues P, Chimelli L, Giangaspero F (2000) Cerebellar liponeurocytoma. In: Pathology and Genetics of Tumors of the Nervous System, Kleihues P, Cavenee WK (eds), Chapter pp. 110-111, IARC Press:Lyon.
35. Ma Y, Pannicke U, Schwarz K, Lieber MR (2002) Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell 108:781-794.
36. Miyaki M, Konishi M, Kikuchi-Yanoshita R, Enomoto M, Igari T, Tanaka K, Muraoka M, Takahashi H, Amada Y, Fukayama M, Maeda Y, Iwama T, Mishima Y, Mori T, Koike M (1994) Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors. Cancer Res 54:3011-3020.
37. Miyoshi Y, Nagase H, Ando H, Horii A, Ichii S, Nakatsuru S, Aoki T, Miki Y, Mori T, Nakamura Y (1992) Somatic mutations of the APC gene in colorectal tumors:mutation cluster region in the APC gene. Hum Mol Genet 1:229-233.
38. Montagna N, az LC, astro MA (1999) Meduloblastoma cerebelar em adulto com areas lipomatosas. J Bras Patol 35:49.
39. Montagna N, Moreira D, Vaz LC, Reis M (2002) Cerebellar liponeurocytoma:a newly recognized clinico-pathological entity. Arq Neuropsiquiatr 60:725-729.
40. Nicholson J, Wickramasinghe C, Ross F, Crolla J, Ellison D (2000) Imbalances of chromosome 17 in medulloblastomas determined by comparative genomic hybridisation and fluorescence in situ hybridisation. Mol Pathol 53:313-319.
41. Nozaki M, Tada M, Matsumoto R, Sawamura Y, Abe H, Iggo RD (1998) Rare occurrence of inactivating p53 gene mutations in primary non-astrocytic tumors of the central nervous system: reappraisal by yeast functional assay. Acta Neuropathol (Berl) 95:291-296.
42. Ohgaki H, Eibl RH, Schwab M, Reichel MB, Mariani L, Gehring M, Petersen I, Holl T, Wiestler OD, Kleihues P (1993) Mutations of the p53 tumor suppressor gene in neoplasms of the human nervous system. Mol Carcinog 8:74-80.
43. Orlandi A, Marino B, Brunori M, Greco R, Spagnoli LG (1997) Lipomatous medulloblastoma. Clin Neuropathol 16:175-179.
44. Perry A, Fuller CE, Banerjee R, Brat DJ, Scheithauer BW (2003) Ancillary FISH analysis for 1p and 19q status: preliminary observations in 287 gliomas and oligodendroglioma mimics. Front Biosci 8:a1-a9.
45. Phelan CM, Liu L, Ruttledge MH, Müntzning K, Ridderheim PA, Collins VP (1995) Chromosome 17 abnormalities and lack of TP53 mutations in paediatric central nervous system tumors. Hum Genet 96:684-690.
46. Pietsch T, Waha A, Koch A, Kraus J, Albrecht S, Tonn J, Sorensen N, Berthold F, Henk B, Schmandt N, Wolf HK, von Deimling A, Wainwright B, Chenevix-Trench G, Wiestler OD, Wicking C (1997) Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched. Cancer Res 57:2085-2088.
47. Portwine C, Chilton-MacNeill S, Brown C, Sexsmith E, McLaughlin J, Malkin D (2001) Absence of germline and somatic p53 alterations in children with sporadic brain tumors. J Neurooncol 52:227-235.
48. Rabbitts TH, Forster A, Larson R, Nathan P (1993) Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma. Nat Genet 4:175-180.
49. Raffel C, Jenkins RB, Frederick L, Hebrink D, Alderete B, Fults DW, James CD (1997) Sporadic medulloblastomas contain PTCH mutations. Cancer Res 57:842-845.
50. Reifenberger J, Ring GU, Gies U, Cobbers L, Oberstrass J, An HX, Niederacher D, Wechsler W, Reifenberger G (1996) Analysis of p53 mutation and epidermal growth factor receptor amplification in recurrent gliomas with malignant progression. J Neuropathol Exp Neurol 55:822-831.
51. Saylors RL3, Sidransky D, Friedman HS, Bigner SH, Bigner DD, Vogelstein B, Brodeur GM (1991) Infrequent p53 gene mutations in medulloblastomas. Cancer Res 51:4721-4723.
52. Shieh SY, Ikeda M, Taya Y, Prives C (1997) DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91:325-334.
53. Soylemezoglu F, Soffer D, Onol B, Schwechheimer K, Kleihues P (1996) Lipomatous medulloblastoma in adults. A distinct clinicopathological entity. Am J Surg Pathol 20:413-418.
54. Taddei GL, Buccoliero AM, Caldarella A, Conti R, Di Lorenzo N, Cacciola F, Franchi A (2001) Cerebellar liponeurocytoma: immunohistochemical and ultrastructural study of a case. Ultrastruct Pathol 25:59-63.
55. Vagner-Capodano AM, Zattara-Cannoni H, Gambarelli D, Gentet JC, Genitori L, Lena G, Graziani N, Raybaud C, Choux M, Grisoli F (1994) Detection of i(17q) chromosome by fluorescent in situ hybridization (FISH) with interphase nuclei in medulloblastoma. Cancer Genet Cytogenet 78: 1-6.
56. Vorechovsky I, Tingby O, Hartman M, Stromberg B, Nister M, Collins VP, Toftgard R (1997) Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumors. Oncogene 15:361-366.
57. Wang W, Kumar P, Whalley J, Schwarz M, Malone G, Haworth A, Kumar S (1998) The mutation status of PAX3 and p53 genes in medulloblastoma. Anticancer Res 18:849-853.
58. Watanabe K, Tachibana O, Sato K, Yonekawa Y, Kleihues P, Ohgaki H (1996) Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol 6:217-224.
59. Wechsler-Reya RJ, Scott MP (1999) Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog. Neuron 22:103-114.
60. Wolter M, Reifenberger J, Sommer C, Ruzicka T, Reifenberger G (1997) Mutations in the human homologue of the Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. Cancer Res 57:2581-2585.
61. Xie J, Johnson RL, Zhang X, Bare JW, Waldman FM, Cogen PH, Menon AG, Warren RS, Chen LC, Scott MP, Epstein EH, Jr. (1997) Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors. Cancer Res 57:2369-2372.
62. Zurawel RH, Allen C, Chiappa S, Cato W, Biegel J, Cogen P, de Sauvage F, Raffel C (2000) Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma. Genes Chromosomes Cancer 27:44-51.
63. Zurawel RH, Chiappa SA, Allen C, Raffel C (1998) Sporadic medulloblastomas contain oncogenic b-catenin mutations. Cancer Res 58: 896-899.