4-Oxalocrotonate tautomerase, its homologue YwhB, and active vinylpyruvate hydratase: Synthesis and evaluation of 2-fluoro substrate analogues

Biochemistry

Volumn 43, Issue 32, 2004, Pages 10490-10501

  Johnson Jr , William H ^a   Wang, Susan C ^a   Stanley, Thanuja M ^a   Czerwinski, Robert M ^a   Almrud, Jeffrey J ^a   Poelarends, Gerrit J ^a   Murzin, Alexey G ^b   Whitman, Christian P ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b MRC CENTRE FOR PROTEIN ENGINEERING   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEXATION; ISOMERS; STRUCTURAL ANALYSIS; SYNTHESIS (CHEMICAL);

LIGANDS; META-FISSION PATHWAYS;

BIOCHEMISTRY;

2 FLUOROPENT 2 EN 4 YNOATE; 4 OXALOCROTONATE DECARBOXYLASE; 4 OXALOCROTONATE TAUTOMERASE; ENZYME; FLUORIDE; FLUORO 2 EN 4 YNOATE; FLUORO 2,4 PENTADIENOATE; FUMARYLACETOACETASE; GLUTAMIC ACID; GLUTAMINE; LIGAND; UNCLASSIFIED DRUG; VINYLPYRUVATE HYDRATASE;

ARTICLE; BACILLUS SUBTILIS; CHEMICAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME ACTIVITY; ENZYME SUBSTRATE; ISOMERISM; METAL BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SYNTHESIS;

ALKANES; ALKYNES; AMINO ACID SEQUENCE; BACILLUS SUBTILIS; BACTERIAL PROTEINS; BINDING, COMPETITIVE; ENZYME INHIBITORS; EVALUATION STUDIES; FLUORINE; HYDRO-LYASES; ISOMERASES; LIGANDS; MOLECULAR SEQUENCE DATA; PENICILLIN-BINDING PROTEINS; PERIPLASMIC PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

BACILLUS SUBTILIS;

EID: 4143059215     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi049489p     Document Type: Article

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