Controlled-release implant system formulated using biodegradable hemostatic gauze as scaffold

International Journal of Pharmaceutics

Volumn 355, Issue 1-2, 2008, Pages 249-258

  Xu, Longji ^a   Wu, Fei ^a   Yuan, Weien ^a   Jin, Tuo ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

BCNU; Controlled release; Drug delivery; Implant; Phenol red; PLGA; Surgicel

Indexed keywords

CARMUSTINE; OXIDIZED REGENERATED CELLULOSE; PHENOLSULFONPHTHALEIN; POLYGLACTIN;

ARTICLE; BIODEGRADABLE IMPLANT; CONTROLLED RELEASE FORMULATION; DIFFERENTIAL SCANNING CALORIMETRY; DIFFUSION; DRUG FORMULATION; DRUG RELEASE; DRUG STRUCTURE; GAUZE DRESSING; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPE; X RAY DIFFRACTION;

ABSORBABLE IMPLANTS; ANTINEOPLASTIC AGENTS, ALKYLATING; CALORIMETRY, DIFFERENTIAL SCANNING; CARMUSTINE; CELLULOSE, OXIDIZED; CRYSTALLIZATION; DELAYED-ACTION PREPARATIONS; KINETICS; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; POLYGLYCOLIC ACID; POLYMERS; SURFACE PROPERTIES; TISSUE SCAFFOLDS; X-RAY DIFFRACTION;

EID: 41349112700     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.12.019     Document Type: Article

References (29)

1. Brannon-Peppas L., and Blanchette J.O. Nanoparticle and targeted systems for cancer therapy. Adv. Drug. Deliv. Rev. 56 (2004) 649-1659
2. Brem H., and Gabikian P. Biodegradable polymer implants to treat brain tumors. J. Control Rel. 74 (2001) 63-67
3. Chae G.S., Lee J.S., Kim S.H., Seo K.Su., Kim M., Lee H.B., and Khang G. Enhancement of the stability of BCNU using self-emulsifying drug delivery systems (SEDDS) and in vitro antitumor activity of self-emulsified BCNU-loaded PLGA water. Int. J. Pharm. 301 (2005) 6-14
4. Dang W.B., Daviau T., Ying P., Zhao Y., Nowotnik D., Clow C.S., Tyler B., and Brem H. Effects of GLIADEL(R) wafer initial molecular weight on the erosion of wafer and release of BCNU. J. Control Rel. 42 (1996) 83-92
5. Domb A.J., Israel Z.H., Elmalak O., Teomim D., and Ben-Tolila A. Preparation and characterization of carmustine loaded polyanhydride wafers for treating brain tumors. Pharm. Res. 16 (1999) 762-765
6. Feng L., Qi X.R., Zhou X.J., Maitani Y., Wang S.C., Jiang Y., and Nagai T. Pharmaceutical and immunological evaluation of a single-dose hepatitis B vaccine using PLGA microspheres. J. Control Rel. 112 (2006) 35-42
7. Gómez C., Blanco M.D., Bernardo M.V., Olmo R., Muñiz E., and Teijón J.M. Cytarabine release from comatrices of albumin microspheres in a poly(lactide-co-glycolide) film: in vitro and in vivo studies. Eur. J. Pharm. Biopharm. 57 (2004) 225-233
8. Guerin C., Olivi A., Weingart J.D., Lawson H.C., and Brem H. Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers. Invest. New Drugs 22 (2004) 27-37
9. Hickey T., Kreutzer D., Burgess D.J., and Moussy F. Dexamethasone/PLGA microspheres for continuous delivery of an anti-inflammatory drug for implantable medical devices. Biomaterials 23 (2002) 1649-1656
10. Huynh G.H., Deen D.F., and Szoka F.C. arriers to carrier mediated drug and gene delivery to brain tumors. J. Control Rel. 110 (2006) 236-259
11. Jain R.A. The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials 21 (2000) 2475-2490
12. Jin, T., Zhu, H., Zhu, J., 2006. Aquespheres, their preparation and uses thereof, US Patent, 6,998,393 (14 February).
13. Kim M.S., Seo S.K., Hyun H., Kim S.K., Khang G., and Lee H.B. Sustained release of bovine serum albumin using implantable wafers prepared by MPEG-PLGA diblock copolymers. Int. J. Pharm. 304 (2005) 165-177
14. Lagman R., Walsh D., and Day K. Oxidized cellulose dressings for persistent bleeding from a superficial malignant tumor. Am. J. Hosp. Palliat. Care 19 (2002) 417-418
15. Lee J.S., An T.K., Chae G.S., Jeong J.K., Cho S.H., Lee H.B., and Khang G. Evaluation of in vitro and in vivo antitumor activity of BCNU-Ioaded PLGA wafer against 9L gliosarcoma. Eur. J. Pharm. Biopharm. 59 (2005) 169-175
16. Painbeni T., Venier-Julienne M.C., and Benoit J.P. Internal morphology of poly(d,l-lactide-co-glycolide) BCNU-loaded microspheres. Influence on drug stability. Eur. J. Pharm. Biopharm. 45 (1998) 31-39
17. Sabel M., and Stummer W. The use of local agents: surgicel and Surgifoam. Euro. Spine J. 13 (2004) S97-S101
18. Seong H., An T.K., Khang G., Choi S., Chong O.L., and Lee H.B. BCNU-loaded poly(d,l-lactide-co-glycolide) wafer and antitumor activity against XF-498 human CNS tumor cells in vitro. Int. J. Pharm. 251 (2003) 1-12
19. Sipos E.P., Tyler B., Piantadosi S., Burger P.C., and Brem H. Optimizing interstitial delivery of BCNU from controlled release polymers for the treatment of brain tumors. Cancer Chemoth. Pharm. 39 (2008) 383-389
20. Sven F., and Daniel E.O. Protein drugs stability: a formulation challenge. Nat. Rev. Drug. Discov. 4 (2005) 298-306
21. Takahashi M., Onishi H., and Machida Y. Development of implant tablet for a week-long sustained release. J. Control Rel. 100 (2004) 63-74
22. Ugo B., Eric A., and Eric D. Strategic approaches for overcoming peptide and protein instability within biodegradable nano- and microparticles. Eur. J. Pharm. Biopharm. 59 (2005) 375-388
23. Wang C.H., Li J., Teo C.S., and Lee T. The delivery of BCNU to brain tumors. J. Control Rel. 61 (1999) 21-41
24. Wang P.P., Frazier J., and Brem H. Local drug delivery to the brain. Adv. Drug. Deliv. Rev. 54 (2002) 987-1013
25. Wang Y., Challa P., Epstein D.L., and Yuan F. Controlled release of ethacrynic acid from poly(lactide-co-glycolide) films for glaucoma treatment. Biomaterials 25 (2004) 4279-4285
26. Witt C., and Kissel T. Morphological characterization of microspheres, films and implants prepared from poly(lactide-co-glycolide) and ABA triblock copolymers: is the erosion controlled by degradation, swelling or diffusion. Eur. J. Pharm. Biopharm. 51 (2001) 171-181
27. Woo B.H., Fink B.F., Page R., Schrier J.A., Jo Y.W., Jiang G., DeLuca M., Vasconez H.C., and Deluca P.P. Enhancement of bone growth by sustained delivery of recombinant human bone morphogenetic protein-2 in a polymeric matrix. Pharm. Res. 18 (2001) 1747-1753
28. Xu X., Chen X., Xu X., Lu T., Wang X., Yang L., and Jing X. BCNU-loaded PEG-PLLA ultrafine fibers and their in vitro antitumor activity against Glioma C6 cells. J. Control Rel. 114 (2006) 16-307
29. Yasukawa T., Ogura Y., Sakurai E., Tabata Y., and Kimura H. Intraocular sustained drug delivery using implantable polymeric devices. Adv. Drug. Deliv. Rev. 57 (2005) 2033-2046. http://store.k12webstore.com/mkgz24.html