-
1
-
-
0037317334
-
Protein folding and disease: a view from the first Horizon Symposium
-
Dobson C.M. Protein folding and disease: a view from the first Horizon Symposium. Nat. Rev. Drug Discov. 2 (2003) 154-160
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 154-160
-
-
Dobson, C.M.1
-
2
-
-
4143141192
-
Self-assembling peptides and proteins for nanotechnological applications
-
Rajagopal K., and Schneider J.P. Self-assembling peptides and proteins for nanotechnological applications. Curr. Opin. Struct. Biol. 14 (2004) 480-486
-
(2004)
Curr. Opin. Struct. Biol.
, vol.14
, pp. 480-486
-
-
Rajagopal, K.1
Schneider, J.P.2
-
4
-
-
1642433249
-
High-resolution molecular structure of a peptide in an amyloid fibril determined by magic angle spinning NMR spectroscopy
-
Jaroniec C.P., MacPhee C.E., Bajaj V.S., McMahon M.T., Dobson C.M., and Griffin R.G. High-resolution molecular structure of a peptide in an amyloid fibril determined by magic angle spinning NMR spectroscopy. Proc. Natl Acad. Sci. USA 101 (2004) 711-716
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 711-716
-
-
Jaroniec, C.P.1
MacPhee, C.E.2
Bajaj, V.S.3
McMahon, M.T.4
Dobson, C.M.5
Griffin, R.G.6
-
5
-
-
28444442999
-
3D structure of Alzheimer's amyloid-β(1-42) fibrils
-
Luhrs T., Ritter C., Adrian M., Riek-Loher D., Bohrmann B., Dobeli H., et al. 3D structure of Alzheimer's amyloid-β(1-42) fibrils. Proc. Natl Acad. Sci. USA 102 (2005) 17342-17347
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 17342-17347
-
-
Luhrs, T.1
Ritter, C.2
Adrian, M.3
Riek-Loher, D.4
Bohrmann, B.5
Dobeli, H.6
-
6
-
-
30744433878
-
Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils
-
Petkova A.T., Yau W.M., and Tycko R. Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils. Biochemistry 45 (2006) 498-512
-
(2006)
Biochemistry
, vol.45
, pp. 498-512
-
-
Petkova, A.T.1
Yau, W.M.2
Tycko, R.3
-
7
-
-
1342324027
-
Progress towards a molecular-level structural understanding of amyloid fibrils
-
Tycko R. Progress towards a molecular-level structural understanding of amyloid fibrils. Curr. Opin. Struct. Biol. 14 (2004) 96-103
-
(2004)
Curr. Opin. Struct. Biol.
, vol.14
, pp. 96-103
-
-
Tycko, R.1
-
8
-
-
20444440728
-
Structure of the cross-beta spine of amyloid-like fibrils
-
Nelson R., Sawaya M.R., Balbirnie M., Madsen A.O., Riekel C., Grothe R., and Eisenberg D. Structure of the cross-beta spine of amyloid-like fibrils. Nature 435 (2005) 773-778
-
(2005)
Nature
, vol.435
, pp. 773-778
-
-
Nelson, R.1
Sawaya, M.R.2
Balbirnie, M.3
Madsen, A.O.4
Riekel, C.5
Grothe, R.6
Eisenberg, D.7
-
9
-
-
34249290108
-
Atomic structures of amyloid cross-beta spines reveal varied steric zippers
-
Sawaya M.R., Sambashivan S., Nelson R., Ivanova M.I., Sievers S.A., Apostol M.I., et al. Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature 447 (2007) 453-457
-
(2007)
Nature
, vol.447
, pp. 453-457
-
-
Sawaya, M.R.1
Sambashivan, S.2
Nelson, R.3
Ivanova, M.I.4
Sievers, S.A.5
Apostol, M.I.6
-
10
-
-
33746800825
-
Molecular dynamics analyses of cross-β-spine steric zipper models: β-sheet twisting and aggregation
-
Esposito L., Pedone C., and Vitagliano L. Molecular dynamics analyses of cross-β-spine steric zipper models: β-sheet twisting and aggregation. Proc. Natl Acad. Sci. USA 103 (2006) 11533-11538
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 11533-11538
-
-
Esposito, L.1
Pedone, C.2
Vitagliano, L.3
-
11
-
-
0029059477
-
Incorporation of glutamine repeats makes protein oligomerize: implications for neurodegenerative diseases
-
Stott K., Blackburn J.M., Butler P.J., and Perutz M. Incorporation of glutamine repeats makes protein oligomerize: implications for neurodegenerative diseases. Proc. Natl Acad. Sci. USA 92 (1995) 6509-6513
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 6509-6513
-
-
Stott, K.1
Blackburn, J.M.2
Butler, P.J.3
Perutz, M.4
-
12
-
-
0000522537
-
Crystal structure of a dimeric chymotrypsin inhibitor 2 mutant containing an inserted glutamine repeat
-
Chen Y.W., Stott K., and Perutz M.F. Crystal structure of a dimeric chymotrypsin inhibitor 2 mutant containing an inserted glutamine repeat. Proc. Natl Acad. Sci. USA 96 (1999) 1257-1261
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 1257-1261
-
-
Chen, Y.W.1
Stott, K.2
Perutz, M.F.3
-
13
-
-
33644873570
-
Structure of amyloid beta fragments in aqueous environments
-
Takano K., Endo S., Mukaiyama A., Chon H., Matsumura H., Koga Y., and Kanaya S. Structure of amyloid beta fragments in aqueous environments. FEBS J. 273 (2006) 150-158
-
(2006)
FEBS J.
, vol.273
, pp. 150-158
-
-
Takano, K.1
Endo, S.2
Mukaiyama, A.3
Chon, H.4
Matsumura, H.5
Koga, Y.6
Kanaya, S.7
-
14
-
-
33845206150
-
Atomic structures of peptide self-assembly mimics
-
Makabe K., McElheny D., Tereshko V., Hilyard A., Gawlak G., Yan S., et al. Atomic structures of peptide self-assembly mimics. Proc. Natl Acad. Sci. USA 103 (2006) 17753-17758
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 17753-17758
-
-
Makabe, K.1
McElheny, D.2
Tereshko, V.3
Hilyard, A.4
Gawlak, G.5
Yan, S.6
-
15
-
-
33947314274
-
Hydrophobic surface burial is the major stability determinant of a flat, single-layer beta-sheet
-
Yan S., Gawlak G., Makabe K., Tereshko V., Koide A., and Koide S. Hydrophobic surface burial is the major stability determinant of a flat, single-layer beta-sheet. J. Mol. Biol. 368 (2007) 230-243
-
(2007)
J. Mol. Biol.
, vol.368
, pp. 230-243
-
-
Yan, S.1
Gawlak, G.2
Makabe, K.3
Tereshko, V.4
Koide, A.5
Koide, S.6
-
16
-
-
0034636976
-
Solution conformation and amyloid-like fibril formation of a polar peptide derived from a β-hairpin in the OspA single-layer β-sheet
-
Ohnishi S., Koide A., and Koide S. Solution conformation and amyloid-like fibril formation of a polar peptide derived from a β-hairpin in the OspA single-layer β-sheet. J. Mol. Biol. 301 (2000) 477-489
-
(2000)
J. Mol. Biol.
, vol.301
, pp. 477-489
-
-
Ohnishi, S.1
Koide, A.2
Koide, S.3
-
17
-
-
0034719388
-
Design of single-layer beta-sheets without a hydrophobic core
-
Koide S., Huang X., Link K., Koide A., Bu Z., and Engelman D.M. Design of single-layer beta-sheets without a hydrophobic core. Nature 403 (2000) 456-460
-
(2000)
Nature
, vol.403
, pp. 456-460
-
-
Koide, S.1
Huang, X.2
Link, K.3
Koide, A.4
Bu, Z.5
Engelman, D.M.6
-
18
-
-
0037022563
-
Natural beta-sheet proteins use negative design to avoid edge-to-edge aggregation
-
Richardson J.S., and Richardson D.C. Natural beta-sheet proteins use negative design to avoid edge-to-edge aggregation. Proc. Natl Acad. Sci. USA 99 (2002) 2754-2759
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 2754-2759
-
-
Richardson, J.S.1
Richardson, D.C.2
-
19
-
-
0346057932
-
Increasing the amphiphilicity of an amyloidogenic peptide changes the beta-sheet structure in the fibrils from antiparallel to parallel
-
Gordon D.J., Balbach J.J., Tycko R., and Meredith S.C. Increasing the amphiphilicity of an amyloidogenic peptide changes the beta-sheet structure in the fibrils from antiparallel to parallel. Biophys. J. 86 (2004) 428-434
-
(2004)
Biophys. J.
, vol.86
, pp. 428-434
-
-
Gordon, D.J.1
Balbach, J.J.2
Tycko, R.3
Meredith, S.C.4
-
20
-
-
0036845354
-
The behaviour of polyamino acids reveals an inverse side chain effect in amyloid structure formation
-
Fandrich M., and Dobson C.M. The behaviour of polyamino acids reveals an inverse side chain effect in amyloid structure formation. EMBO J. 21 (2002) 5682-5690
-
(2002)
EMBO J.
, vol.21
, pp. 5682-5690
-
-
Fandrich, M.1
Dobson, C.M.2
-
21
-
-
20444403757
-
Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases
-
Pawar A.P., Dubay K.F., Zurdo J., Chiti F., Vendruscolo M., and Dobson C.M. Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases. J. Mol. Biol. 350 (2005) 379-392
-
(2005)
J. Mol. Biol.
, vol.350
, pp. 379-392
-
-
Pawar, A.P.1
Dubay, K.F.2
Zurdo, J.3
Chiti, F.4
Vendruscolo, M.5
Dobson, C.M.6
-
23
-
-
0242628911
-
Structural transitions involved in a novel amyloid-like beta-sheet assemblage of tripeptide derivatives
-
Ganesh S., and Jayakumar R. Structural transitions involved in a novel amyloid-like beta-sheet assemblage of tripeptide derivatives. Biopolymers 70 (2003) 336-345
-
(2003)
Biopolymers
, vol.70
, pp. 336-345
-
-
Ganesh, S.1
Jayakumar, R.2
-
24
-
-
0031592945
-
Common core structure of amyloid fibrils by synchrotron X-ray diffraction
-
Sunde M., Serpell L.C., Bartlam M., Fraser P.E., Pepys M.B., and Blake C.C. Common core structure of amyloid fibrils by synchrotron X-ray diffraction. J. Mol. Biol. 273 (1997) 729-739
-
(1997)
J. Mol. Biol.
, vol.273
, pp. 729-739
-
-
Sunde, M.1
Serpell, L.C.2
Bartlam, M.3
Fraser, P.E.4
Pepys, M.B.5
Blake, C.C.6
-
26
-
-
1942457259
-
Conformational heterogeneity of an equilibrium folding intermediate quantified and mapped by scanning mutagenesis
-
Yan S., Gawlak G., Smith J., Silver L., Koide A., and Koide S. Conformational heterogeneity of an equilibrium folding intermediate quantified and mapped by scanning mutagenesis. J. Mol. Biol. 338 (2004) 811-825
-
(2004)
J. Mol. Biol.
, vol.338
, pp. 811-825
-
-
Yan, S.1
Gawlak, G.2
Smith, J.3
Silver, L.4
Koide, A.5
Koide, S.6
-
27
-
-
33746565309
-
Atomic-resolution crystal structure of Borrelia burgdorferi outer surface protein A via surface engineering
-
Makabe K., Tereshko V., Gawlak G., Yan S., and Koide S. Atomic-resolution crystal structure of Borrelia burgdorferi outer surface protein A via surface engineering. Protein Sci. 15 (2006) 1907-1914
-
(2006)
Protein Sci.
, vol.15
, pp. 1907-1914
-
-
Makabe, K.1
Tereshko, V.2
Gawlak, G.3
Yan, S.4
Koide, S.5
-
28
-
-
0029058159
-
An analysis of side chain interactions and pair correlations within antiparallel beta-sheets: the differences between backbone hydrogen-bonded and non-hydrogen-bonded residue pairs
-
Wouters M.A., and Curmi P.M. An analysis of side chain interactions and pair correlations within antiparallel beta-sheets: the differences between backbone hydrogen-bonded and non-hydrogen-bonded residue pairs. Proteins: Struct., Funct., Genet. 22 (1995) 119-131
-
(1995)
Proteins: Struct., Funct., Genet.
, vol.22
, pp. 119-131
-
-
Wouters, M.A.1
Curmi, P.M.2
-
29
-
-
0027173033
-
Weak points of antiparallel beta-sheets. How are they filled up in globular proteins?
-
Finkelstein A.V., and Nakamura H. Weak points of antiparallel beta-sheets. How are they filled up in globular proteins?. Protein Eng. 6 (1993) 367-372
-
(1993)
Protein Eng.
, vol.6
, pp. 367-372
-
-
Finkelstein, A.V.1
Nakamura, H.2
-
31
-
-
33750430630
-
Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Aβ42 peptide
-
Kim W., and Hecht M.H. Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Aβ42 peptide. Proc. Natl Acad. Sci. USA 103 (2006) 15824-15829
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 15824-15829
-
-
Kim, W.1
Hecht, M.H.2
-
33
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Otwinowski Z., and Minor W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276 (1997) 307-326
-
(1997)
Methods Enzymol.
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
34
-
-
3543012707
-
Crystallography & NMR System: a new software suite for macromolecular structure determination
-
Brunger A.T., Adams P.D., Clore G.M., DeLano W.L., Gros P., Grosse-Kunstleve R.W., et al. Crystallography & NMR System: a new software suite for macromolecular structure determination. Acta Crystallogr., Sect. D: Biol. Crystallogr. 54 (1998) 905-921
-
(1998)
Acta Crystallogr., Sect. D: Biol. Crystallogr.
, vol.54
, pp. 905-921
-
-
Brunger, A.T.1
Adams, P.D.2
Clore, G.M.3
DeLano, W.L.4
Gros, P.5
Grosse-Kunstleve, R.W.6
|