Understanding the structural and functional differences between mouse thyrotropin-releasing hormone receptors 1 and 2

Proteins: Structure, Function and Genetics

Volumn 71, Issue 2, 2008, Pages 783-794

  Deflorian, Francesca ^a   Engel, Stanislav ^a   Colson, Anny Odile ^a   Raaka, Bruce M ^a   Gershengorn, Marvin C ^a   Costanzi, Stefano ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Activation; Conformational changes; Docking; GPCR; Homology modeling; Molecular dynamics; Monte Carlo search; Mutagenesis; TM5 rotation; TRH receptors

Indexed keywords

MUTANT PROTEIN; PROTIRELIN RECEPTOR; PROTIRELIN RECEPTOR 1; PROTIRELIN RECEPTOR 2; RHODOPSIN; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CELL STRAIN HEK293; COMPARATIVE STUDY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CORRELATION ANALYSIS; COW; CRYSTAL STRUCTURE; EMBRYO; ENERGY; HUMAN; HUMAN CELL; MEMBRANE; MOLECULAR DYNAMICS; MOLECULAR MODEL; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; SIMULATION; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CATTLE; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MONTE CARLO METHOD; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, THYROTROPIN-RELEASING HORMONE; RHODOPSIN; SEQUENCE ALIGNMENT; THYROTROPIN-RELEASING HORMONE;

BOVINAE; MURINAE;

EID: 41149160907     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21763     Document Type: Article

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