Stimulation of UT-A1-mediated transepithelial urea flux in MDCK cells by lithium

American Journal of Physiology - Renal Physiology

Volumn 294, Issue 3, 2008, Pages

  Fröhlich, Otto ^a,b   Aggarwal, Deepak ^b   Klein, Janet D ^b   Kent, Kimilia J ^b   Yang, Yuan ^a   Gunn, Robert B ^a   Sands, Jeff M ^a,b  

^a EMORY UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cyclic AMP; Madin Darby canine kidney cells

Indexed keywords

AMILORIDE; CARRIER PROTEIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; ISOBUTYLMETHYLXANTHINE; LITHIUM CHLORIDE; PROTEIN UT A1; UNCLASSIFIED DRUG; UREA; VASOPRESSIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DOG; KIDNEY COLLECTING TUBULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON SODIUM EXCHANGE; SIGNAL TRANSDUCTION; STIMULUS RESPONSE; WATER PERMEABILITY;

EID: 41149149102     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00349.2007     Document Type: Article

References (37)

1. Boton R, Gaviria M, Batlle DC. Prevalence, pathogenesis, and treatment of renal dysfunction associated with chronic lithium therapy. Am J Kidney Dis 10: 329-345, 1987.
2. Christensen BM, Marples D, Kim YH, Wang W, Frokiær J, Nielsen S. Changes in cellular composition of kidney collecting duct cells in rats with lithium-induced NDI. Am J Physiol Cell Physiol 286: C952-C964, 2004.
3. Christensen S, Kusano E, Yusufi AN, Murayama N, Dousa TP. Pathogenesis of nephrogenic diabetes insipidus due to chronic administration of lithium in rats. J Clin Invest 75: 1869-1879, 1985.
4. Cogan E, Abramow M. Inhibition by lithium of the hydroosmotic action of vasopressin in the isolated perfused cortical collecting tubule of the rabbit. J Clin Invest 77: 1507-1514, 1986.
5. Cogan E, Svoboda M, Abramow M. Mechanisms of lithium-vasopressin interaction in rabbit cortical collecting tubule. Am J Physiol Renal Fluid Electrolyte Physiol 252: F1080-F1087, 1987.
6. De Rooij J, Rehmann H, van Triest M, Cool RH, Wittinghofer A, Bos JL. Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs. J Biol Chem 275: 20829-20836, 2000.
7. Fröhlich O, Klein JD, Smith PM, Sands JM, Gunn RB. Regulation of UT-A1-mediated transepithelial urea flux in MDCK cells. Am J Physiol Cell Physiol 291: C600-C606, 2006.
8. Fröhlich O, Klein JD, Smith PM, Sands JM, Gunn RB. Urea transport in MDCK cells that are stably transfected with UT-A1. Am J Physiol Cell Physiol 286: C1264-C1270, 2004.
9. Garty H, Palmer LG. Epithelial sodium channels: function, structure, and regulation. Physiol Rev 77: 359-396, 1997.
10. Goldberg H, Clayman P, Skorecki K. Mechanism of Li inhibition of vasopressin-sensitive adenylate cyclase in cultured renal epithelial cells. Am J Physiol Renal Fluid Electrolyte Physiol 255: F995-F1002, 1988.
11. Gould TD, Quiroz JA, Singh J, Zarate CA, Manji HK. Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers. Mol Psychiatry 9: 734-755, 2004.
12. Henn V, Stefan E, Baillie GS, Houslay MD, Rosenthal W, Klussmann E. Compartmentalized cAMP signalling regulates vasopressin-mediated water reabsorption by controlling aquaporin-2. Biochem Soc Trans 33: 1316-1318, 2005.
13. Ishikawa S. Cellular actions of arginine vasopressin in the kidney. Endocr J 40: 373-386, 1993.
14. Klein JD, Fröhlich O, Blount MA, Martin CF, Smith TD, Sands JM. Vasopressin increases plasma membrane accumulation of urea transporter UT-A1 in rat inner medullary collecting ducts. J Am Soc Nephrol 17: 2680-2686, 2006.
15. Klein JD, Gunn RB, Roberts BR, Sands JM. Downregulation of urea transporters in the renal inner medulla of lithium-fed rats. Kidney Int 61: 995-1002, 2002.
16. Kotnik P, Nielsen J, Kwon TH, Krzisnik C, Frokiær J, Nielsen S. Altered expression of COX-1, COX-2, and mPGES in rats with nephrogenic and central diabetes insipidus. Am J Physiol Renal Physiol 288: F1053-F1068, 2005.
17. + transporters in rats with lithium-induced NDI. Am J Physiol Renal Physiol 279: F552-F564, 2000.
18. Laursen UH, Pihakaski-Maunsbach K, Kwon TH, Ostergaard Jensen E, Nielsen S, Maunsbach AB. Changes of rat kidney AQP2 and Na, K-ATPase mRNA expression in lithium-induced nephrogenic diabetes insipidus. Nephron Exp Nephrol 97: e1-e16, 2004.
19. Lenox RH, McNamara RK, Papke RL, Manji HK. Neurobiology of lithium: an update. J Clin Psychiatry 59, Suppl 6: 37-47, 1998.
20. Li Y, Shaw S, Kamsteeg EJ, Vandewalle A, Deen PM. Development of lithium-induced nephrogenic diabetes insipidus is dissociated from adenylyl cyclase activity. J Am Soc Nephrol 17: 1063-1072, 2006.
21. Marples D, Christensen S, Christensen EI, Ottosen PD, Nielsen S. Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla. J Clin Invest 95: 1838-1845, 1995.
22. Matsumura Y, Uchida S, Rai T, Sasaki S, Marumo F. Transcriptional regulation of aquaporin-2 water channel gene by cAMP. J Am Soc Nephrol 8: 861-867, 1997.
23. McSorley T, Stefan E, Henn V, Wiesner B, Baillie GS, Houslay MD, Rosenthal W, Klussmann E. Spatial organisation of AKAP18 and PDE4 isoforms in renal collecting duct principal cells. Eur J Cell Biol 85: 673-678, 2006.
24. Nielsen S, Chou CL, Marples D, Christensen EI, Kishore BK, Knepper MA. Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane. Proc Natl Acad Sci USA 92: 1013-1017, 1995.
25. Presne C, Fakhouri F, Noel LH, Stengel B, Even C, Kreis H, Mignon F, Grunfeld JP. Lithium-induced nephropathy: rate of progression and prognostic factors. Kidney Int 64: 585-592, 2003.
26. Rao R, Zhang MZ, Zhao M, Cai H, Harris RC, Breyer MD, Hao CM. Lithium treatment inhibits renal GSK-3 activity and promotes cyclooxygenase 2-dependent polyuriarats. Am J Physiol Renal Physiol 288: F642-F649, 2005.
27. +- antiport in cultured dog kidney cells (MDCK). J Biol Chem 256: 10820-10825, 1981.
28. Rojek A, Nielsen J, Brooks HL, Gong H, Kim YH, Kwon TH, Frokær J, Nielsen S. Altered expression of selected genes in kidney of rats with lithium-induced NDI. Am J Physiol Renal Physiol 288: F1276-F1289, 2005.
29. Sands JM. Mammalian urea transporters. Annu Rev Physiol 65: 543-566, 2003.
30. Stefan E, Wiesner B, Baillie GS, Mollajew R, Henn V, Lorenz D, Furkert J, Santamaria K, Nedvetsky P, Hundsrucker C, Beyermann M, Krause E, Pohl P, Gall I, MacIntyre AN, Bachmann S, Houslay MD, Rosenthal W, Klussmann E. Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells. J Am Soc Nephrol 18: 199-212, 2007.
31. Timmer RT, Sands JM. Lithium intoxication. J Am Soc Nephrol 10: 666-674, 1999.
32. Walker RG. Lithium nephrotoxicity. Kidney Int Suppl 42: S93-S98, 1993.
33. Wall SM, Han JS, Chou CL, Knepper MA. Kinetics of urea and water permeability activation by vasopressin in rat terminal IMCD. Am J Physiol Renal Fluid Electrolyte Physiol 262: F989-F998, 1992.
34. Willoughby D, Wong W, Schaack J, Scott JD, Cooper DM. An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamics. EMBO J 25: 2051-2061, 2006.
35. Yamaki M, Kusano E, Tetsuka T, Takeda S, Homma S, Murayama N, Asano Y. Cellular mechanism of lithium-induced nephrogenic diabetes insipidus in rats. Am J Physiol Renal Fluid Electrolyte Physiol 261: F505-F511, 1991.
36. Yasui M, Zelenin SM, Celsi G, Aperia A. Adenylate cyclase-coupled vasopressin receptor activates AQP2 promoter via a dual effect on CRE and AP1 elements. Am J Physiol Renal Physiol 272: F443-F450, 1997.
37. Zhang C, Sands JM, Klein JD. Vasopressin rapidly increases phosphorylation of UT-A1 urea transporter in rat IMCDs through PKA. Am J Physiol Renal Physiol 282: F85-F90, 2002.