Vancomycin derivative with damaged D-Ala-D-Ala binding cleft binds to cross-linked peptidoglycan in the cell wall of Staphylococcus aureus

Biochemistry

Volumn 47, Issue 12, 2008, Pages 3822-3831

  Sung, Joon Kim ^a   Matsuoka, Shigeru ^a,b   Patti, Gary J ^a   Schaefer, Jacob ^a  

^a WASHINGTON UNIVERSITY   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDOGLYCAN; STAPHYLOCOCCUS AUREUS; VANCOMYCIN DERIVATIVES;

BACTERIA; BINDING ENERGY; CROSSLINKING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

PATHOGENS;

CARBON 13; DES N METHYLLEUCYL 4 (4 FLUOROPHENYL)BENZYL VANCOMYCIN; DEXTRO ALANINE; FLUORINE; GLYCINE; LYSINE; NITROGEN 15; PEPTIDOGLYCAN; UNCLASSIFIED DRUG; VANCOMYCIN DERIVATIVE;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL CELL WALL; BINDING SITE; CONTROLLED STUDY; CROSS LINKING; ISOTOPE LABELING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; STAPHYLOCOCCUS AUREUS;

BINDING SITES; CELL WALL; CROSS-LINKING REAGENTS; DIPEPTIDES; MOLECULAR CONFORMATION; PEPTIDOGLYCAN; STAPHYLOCOCCUS AUREUS; VANCOMYCIN;

STAPHYLOCOCCUS AUREUS;

EID: 41149127707     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi702232a     Document Type: Article

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