Modeling cellular metabolism and energetics in skeletal muscle: Large-scale parameter estimation and sensitivity analysis

IEEE Transactions on Biomedical Engineering

Volumn 55, Issue 4, 2008, Pages 1298-1318

  Dash, Ranjan K ^a,b   Li, Yanjun ^c   Kim, Jaeyeon ^c   Saidel, Gerald M ^c   Cabrera, Marco E ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c Case Western Reserve University   (United States)

Author keywords

Cellular metabolism; Computer simulation; Dynamic mass balances; Ischemia; Mathematical modeling; Optimal parameter estimation; Sensitivity analysis; Skeletal muscle

Indexed keywords

COMPUTER SIMULATION; DYNAMIC RESPONSE; MATHEMATICAL MODELS; MEDICAL PROBLEMS; MUSCULOSKELETAL SYSTEM; PARAMETER ESTIMATION; PHYSIOLOGICAL MODELS; SENSITIVITY ANALYSIS;

CELLULAR METABOLISM; DYNAMIC MASS BALANCES; ISCHEMIA; OPTIMAL PARAMETER ESTIMATION; SKELETAL MUSCLE;

METABOLISM;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ARTICLE; BLOOD FLOW; CAPILLARY BLOOD; CELL METABOLISM; ENERGY TRANSFER; ISCHEMIA; MATHEMATICAL MODEL; MICHAELIS MENTEN KINETICS; SENSITIVITY ANALYSIS; SKELETAL MUSCLE; VALIDATION STUDY;

ANIMALS; COMPUTER SIMULATION; ENERGY METABOLISM; HUMANS; MODELS, BIOLOGICAL; MUSCLE FIBERS; MUSCLE, SKELETAL; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 41149083382     PISSN: 00189294     EISSN: None     Source Type: Journal    
DOI: 10.1109/TBME.2007.913422     Document Type: Article

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