Potent inhibition of drug-resistant HIV protease variants by monoclonal antibodies

Antiviral Research

Volumn 78, Issue 3, 2008, Pages 275-277

  Bartoňová, Vanda ^a   Král, Vlastimil ^a   Sieglová, Irena ^a   Brynda, Jiří ^a,b   Fábry, Milan ^a   Hořejší, Magdalena ^a   Kožíšek, Milan ^b   Šašková, Klára Grantz ^b   Konvalinka, Jan ^a,b   Sedláček, Juraj ^a   Řezáčová, Pavlína ^a,b  

^a INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^b INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

Dissociative inhibition; Drug resistance; HIV protease; Inhibiting antibody

Indexed keywords

EPITOPE; INDINAVIR; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 1696; MONOCLONAL ANTIBODY F11.2.32; PROTEINASE; RITONAVIR; SAQUINAVIR; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; ENZYME ACTIVE SITE; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO SELECTION; NONHUMAN; PRIORITY JOURNAL; PROTEINASE INHIBITION; VIRUS MUTATION;

ANTIBODIES, MONOCLONAL; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; DIMERIZATION; DRUG RESISTANCE, VIRAL; HIV INFECTIONS; HIV PROTEASE; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; IMMUNOGLOBULIN FRAGMENTS; MODELS, MOLECULAR; MUTATION; RECOMBINANT PROTEINS; VARIATION (GENETICS);

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 41049113236     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2008.01.009     Document Type: Article

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