Synthetic liver X receptor agonist T0901317 inhibits semicarbazide- sensitive amine oxidase gene expression and activity in apolipoprotein e knockout mice

Acta Biochimica et Biophysica Sinica

Volumn 40, Issue 3, 2008, Pages 261-268

  Dai, Xiaoyan ^a   Ou, Xiang ^a   Hao, Xinrui ^a   Cao, Dongli ^a   Tang, Yaling ^a   Hu, Yanwei ^a   Li, Xiaoxu ^a   Tang, Chaoke ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Atherosclerosis; Liver X receptor; Nuclear receptor; Semicarbazide sensitive amine oxidase; T0901317

Indexed keywords

AMINE OXIDASE (COPPER CONTAINING); APOLIPOPROTEIN E; CELL ADHESION MOLECULE; CELL RECEPTOR; DNA BINDING PROTEIN; LIVER X RECEPTOR; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; SEMICARBAZIDE SENSITIVE AMINE OXIDASE VASCULAR ADHESION PROTEIN 1, MOUSE; SEMICARBAZIDE-SENSITIVE AMINE OXIDASE-VASCULAR ADHESION PROTEIN-1, MOUSE; SULFONAMIDE; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; ATHEROSCLEROSIS; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; MOUSE; MOUSE MUTANT;

AMINE OXIDASE (COPPER-CONTAINING); ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CELL ADHESION MOLECULES; DNA-BINDING PROTEINS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MALE; MICE; MICE, KNOCKOUT; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SULFONAMIDES;

MUS; TRIFLUORO;

EID: 41049110043     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1111/j.1745-7270.2008.00391.x     Document Type: Article

References (58)

1. Yu PH, Lu LX, Fan H, Kazachkov M, Jiang ZJ, Jalkanen S, Stolen C. Involvement of semicarbazide-sensitive amine oxidase-mediated deamination in lipopolysaccharide-induced pulmonary inflammation. Am J Pathol 2006, 168 : 718 726.
2. Bour S, Daviaud D, Gres S, Lefort C, Prevot D, Zorzano A, Wabitsch M et al. Adipogenesis-related increase of semicarbazide-sensitive amine oxidase and monoamine oxidase in human adipocytes. Biochimie 2007, 89 : 916 925.
3. Wanecq E, Bour S, Verwaerde P, Smih F, Valet P, Carpene C. Increased monoamine oxidase and semicarbazide-sensitive amine oxidase activities in white adipose tissue of obese dogs fed a high-fat diet. J Physiol Biochem 2006, 62 : 113 123.
4. Yu PH. Oxidative deamination of aliphatic amines by rat aorta semicarbazide-sensitive amine oxidase. J Pharm Pharmacol 1990, 42 : 882 884.
5. Boor PJ, Trent MB, Lyles GA, Tao M, Ansari GA. Methylamine metabolism to formaldehyde by vascular semicarbazide-sensitive amine oxidase. Toxicology 1992, 73 : 251 258.
6. Porter DJ. Binding of 2-acetylpyridine-5-[(2-chloroanilino) thiocarbonyl] thiocarbonohydrazone (BW348U87) to human serum albumin. Biochem Pharmacol 1992, 44 : 1417 1429.
7. Lyles GA. Substrate-specificity of mammalian tissue-bound semicarbazide-sensitive amine oxidase. Prog Brain Res 1995, 106 : 293 303.
8. Salmi M, Stolen C, Jousilahti P, Yegutkin GG, Tapanainen P, Janatuinen T, Knip M et al. Insulin-regulated increase of soluble vascular adhesion protein-l in diabetes. Am J Pathol 2002, 161 : 2255 2262.
9. Boomsma F, van den Meiracker AH, Winkel S, Aanstoot HJ, Batstra MR, Man in't Veld AJ, Bruining GJ. Circulating semicarbazide-sensitive amine oxidase is raised both in type I (insulin-dependent), in type II (non-insulin-dependent) diabetes mellitus and even in childhood type I diabetes at first clinical diagnosis. Diabetologia 1999, 42 : 233 237.
10. Karadi I, Meszaros Z, Csanyi A, Szombathy T, Hosszufalusi N, Romics L, Magyar K. Serum semicarbazide-sensitive amine oxidase (SSAO) activity is an independent marker of carotid atherosclerosis. Clin Chim Acta 2002, 323 : 139 146.
11. Meszaros Z, Karadi I, Csanyi A, Szombathy T, Romics L, Magyar K. Determination of human serum semicarbazide-sensitive amine oxidase activity: a possible clinical marker of atherosclerosis. Eur J Drug Metab Pharmacokinet 1999, 24 : 299 302.
12. Boomsma F, van Veldhuisen DJ, de Kam PJ, Man in't Veld AJ, Mosterd A, Lie KI, Schalekamp MA. Plasma semicarbazide-sensitive amine oxidase is elevated in patients with congestive heart failure. Cardiovasc Res 1997, 33 : 387 391.
13. Boomsma F, de Kam PJ, Tjeerdsma G, van den Meiracker AH, van Veldhuisen DJ. Plasma semicarbazide-sensitive amine oxidase (SSAO) is an independent prognostic marker for mortality in chronic heart failure. Eur Heart J 2000, 21 : 1859 1863.
14. Meszaros Z, Szombathy T, Raimondi L, Karadi I, Romics L, Magyar K. Elevated serum semicarbazide-sensitive amine oxidase activity in non-insulin-dependent diabetes mellitus. Correlation with body mass index and serum triglyceride. Metabolism 1999, 48 : 113 117.
15. Kurkijärvi R, Yegutkin GG, Gunson BK, Jalkanen S, Salmi M, Adams DH. Circulating soluble vascular adhesion protein 1 accounts for the increased serum monoamine oxidase activity in chronic liver disease. Gastroenterology 2000, 119 : 1096 1103.
16. Kurkijarvi R, Adams DH, Leino R, Mottonen T, Jalkanen S, Salmi M. Circulating form of human vascular adhesion protein-1 (VAP-1): increased serum levels in inflammatory liver diseases. J Immunol 1998, 161 : 1549 1557.
17. Lehmann JM, Kliewer SA, Moore LB, Smith-Oliver TA, Oliver BB, Su JL, Sundseth SS et al. Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. J Biol Chem 1997, 272 : 3137 3140.
18. Tangirala RK, Bischoff ED, Joseph SB, Wagner BL, Walczak R, Laffitte BA, Daige CL et al. Identification of macrophage liver X receptors as inhibitors of atherosclerosis. Proc Natl Acad Sci USA 2002, 99 : 11896 11901.
19. Joseph SB, Castrillo A, Laffitte BA, Mangelsdorf DJ, Tontonoz P. Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat Med 2003, 9 : 213 219.
20. Joseph SB, McKilligin E, Pei L, Watson MA, Collins AR, Laffitte BA, Chen M et al. Synthetic LXR ligand inhibits the development of atherosclerosis in mice. Proc Natl Acad Sci USA 2002, 99 : 7604 7609.
21. Terasaka N, Hiroshima A, Koieyama T, Ubukata N, Morikawa Y, Nakai D, Inaba T. T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice. FEBS Lett 2003, 536 : 6 11.
22. Geyeregger R, Zeyda M, Stulnig TM. Liver X receptors in cardiovascular and metabolic disease. Cell Mol Life Sci 2006, 63 : 524 539.
23. Kennedy MA, Venkateswaran A, Tarr PT, Xenarios I, Kudoh J, Shimizu N, Edwards PA. Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein. J Biol Chem 2001, 276 : 39438 39447.
24. Sabol SL, Brewer HB Jr., Santamarina-Fojo S. The human ABCG1 gene: identification of LXR response elements that modulate expression in macrophages and liver. J Lipid Res 2005, 46 : 2151 2167.
25. Tang CK, Yi GH, Yang JH, Liu LS, Wang Z, Ruan CG, Yang YZ. Oxidized LDL upregulated ATP binding cassette transporter A1 in THP-1 macrophages. Acta Pharmacol Sin 2004, 25 : 581 586.
26. Tang CK, Tang GH, Yi GH, Wang Z, Liu LS, Wan S, Yuan ZH et al. Effect of apolipoprotein A-I on ATP binding cassette transporter A1 degradation and cholesterol efflux in THP-1 macrophage-derived foam cells. Acta Biochim Biophys Sin 2004, 36 : 218 226.
27. Tang CK, Yang JH, Yi GH, Wang Z, Liu LS, Wan ZY, Yuan ZH et al. Effects of oleate on ATP binding cassette transporter A1 expression and cholesterol efflux in THP-1 macrophage-derived foam cells. Acta Biochim Biophys Sin 2003, 35 : 1077 1082.
28. Castrillo A, Joseph SB, Vaidya SA, Haberland M, Fogelman AM, Cheng G, Tontonoz P. Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism. Mol Cell 2003, 12 : 805 816.
29. Harrison D, Griendling KK, Landmesser U, Hornig B, Drexler H. Role of oxidative stress in atherosclerosis. Am J Cardiol 2003, 91 : 7A 11A.
30. Somers MJ, Harrison DG. Reactive oxygen species and the control of vasomotor tone. Curr Hypertens Rep 1999, 1 : 102 108.
31. Levonen AL, Patel RP, Brookes P, Go YM, Jo H, Parthasarathy S, Anderson PG et al. Mechanisms of cell signaling by nitric oxide and peroxynitrite: from mitochondria to MAP kinases. Antioxid Redox Signal 2001, 3 : 215 229.
32. Gokturk C, Nordquist J, Sugimoto H, Forsberg-Nilsson K, Nilsson J, Oreland L. Semicarbazide-sensitive amine oxidase in transgenic mice with diabetes. Biochem Biophys Res Commun 2004, 325 : 1013 1020.
33. Feng JL, Chen SN, Tang XS, Ding XF, Du ZY, Chen JS. Quantitative determination of cucumber mosaic virus genome RNAs in virions by real-time reverse transcription-polymerase chain reaction. Acta Biochim Biophys Sin 2006, 38 : 669 676.
34. McCaman RE. Microdetermination of catechol-O-methyl transferase in brain. Life Sci 1965, 4 : 2353 2359.
35. Lowry O, Rosebrough N, Farr A, Randall R. Protein measurement with the Folin phenol reagent. J Biol Chem 1951, 193 : 265 275.
36. Dai K, Qi JY, Tian DY. Leptin administration exacerbates thioacetamide-induced liver fibrosis in mice. World J Gastroenterol 2005, 11 : 4822 4826.
37. Claudel T, Leibowitz MD, Fiévet C, Tailleux A, Wagner B, Repa JJ, Torpier G et al. Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor. Proc Natl Acad Sci USA 2001, 98 : 2610 2615.
38. Aiello RJ, Bourassa PA, Lindsey S, Weng W, Freeman A, Showell HJ. Leukotriene B4 receptor antagonism reduces monocytic foam cells in mice. Arterioscler Thromb Vasc Biol 2002, 22 : 443 449.
39. Marleau S, Harb D, Bujold K, Avallone R, Iken K, Wang Y, Demers A et al. EP 80317, a ligand of the CD36 scavenger receptor, protects apolipoprotein E-deficient mice from developing atherosclerotic lesions. FASEB J 2005, 19 : 1869 1871.
40. Navab M, Berliner JA, Watson AD, Hama SY, Territo MC, Lusis AJ, Shih DM et al. The yin and yang of oxidation in the development of the fatty streak. Arterioscler Thromb Vasc Biol 1996, 16 : 831 842.
41. Ross R. Atherosclerosis - an inflammatory disease. N Eng J Med 1999, 340 : 115 126.
42. Ross R, Harker L. Hyperlipidemia and atherosclerosis. Science 1976, 193 : 1094 1100.
43. Sanders M. Molecular and cellular concepts in atherosclerosis. Pharmacol Ther 1994, 61 : 109 153.
44. Lewis GF, Rader DJ. New insights into the regulation of HDL metabolism and reverse cholesterol transport. Circ Res 2005, 96 : 1221 1232.
45. Chiang JY, Kimmel R, Stroup D. Regulation of cholesterol 7 alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRα). Gene 2001, 262 : 257 265.
46. Repa JJ, Berge KE, Pomajzl C, Richardson JA, Hobbs H, Mangelsdorf DJ. Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta. J Biol Chem 2002, 277 : 18793 18800.
47. Castrillo A, Joseph SB, Marathe C, Mangelsdorf DJ, Tontonoz P. Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages. J Biol Chem 2003, 278 : 10443 10449.
48. Terasaka N, Hiroshima A, Ariga A, Honzumi S, Koieyama T, Inaba T, Fujiwara T. Liver X receptor agonists inhibit tissue factor expression in macrophages. FEBS J 2005, 272 : 1546 1556.
49. Ogawa D, Stone JF, Takata Y, Blaschke F, Chu VH, Towler DA, Law RE et al. Liver X receptor agonists inhibit cytokine-induced osteopontin expression in macrophages through interference with activator protein-1 signaling pathways. Circ Res 2005, 96 : e59 e67.
50. -/- mice fed a high-fat/high-cholesterol diet. Inflammation 2007, 30 : 105 117.
51. Yu PH. Deamination of methylamine and angiopathy; toxicity of formaldehyde, oxidative stress and relevance to protein glycoxidation in diabetes. J Neural Transm Suppl 1998, 52 : 201 216.
52. Zhang YM, Chen XM, Wu D, Zhang XG, Lu Y, Shi SZ, Yin Z. Expression of tissue inhibitor of matrix metalloproteinase-1 in aging of transgenic mouse liver. Chin Med J 2006, 119 : 504 509.
53. Didion SP, Ryan MJ, Didion LA, Fegan PE, Sigmund CD, Faraci FM. Increased superoxide and vascular dysfunction in CuZnSOD-deficient mice. Circ Res 2002, 91 : 938 944.
54. Chen L, Pan DD, Zhou J, Jiang YZ. Protective effect of selenium-enriched Lactobacillus on CCl4-induced liver injury in mice and its possible mechanisms. World J Gastroenterol 2005, 11 : 5795 5800.
55. Paigen B, Morrow A, Brandon C, Mitchell D, Holmes P. Variation in susceptibility to atherosclerosis among inbred strains of mice. Atherosclerosis 1985, 57 : 65 73.
56. Paigen B, Ishida BY, Verstuyft J, Winters RB, Albee D. Athero sclerosis susceptibility differences among progenitors of recombi-nant inbred strains of mice. Arteriosclerosis 1990, 10 : 316 323.
57. Yu PH, Deng YL. Endogenous formaldehyde as a potential factor of vulnerability of atherosclerosis: involvement of semicarbazide-sensitive amine oxidase-mediated methylamine turnover. Atherosclerosis 1998, 140 : 357 363.
58. Yu PH, Wang M, Deng YL, Fan H, Shira-Bock L. Involvement of semicarbazide-sensitive amine oxidase-mediated deamination in atherogenesis in KKAy diabetic mice fed with high cholesterol diet. Diabetologia 2002, 45 : 1255 1262.