Determination of human serum semicarbazide-sensitive amine oxidase activity: A possible clinical marker of atherosclerosis

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 24, Issue 4, 1999, Pages 299-302

  Mészáros, Zsuza ^a,c   Karadi I ^a   Csanyi A ^b   Szombathy, T ^a   Romics, L ^a   Magyar, K ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b Petz Aladár Hospital   (Hungary)

^c NONE   (Hungary)

Author keywords

Atherosclerosis; Risk factor; Semicarbazide sensitive amine oxidase

Indexed keywords

AMINE OXIDASE (COPPER CONTAINING); BENZYLAMINE; GLIBENCLAMIDE; GLICLAZIDE; GLIPIZIDE;

ADULT; AGED; ARTICLE; ATHEROSCLEROSIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIABETIC ANGIOPATHY; DISEASE SEVERITY; ECHOGRAPHY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOGENESIS; PROGNOSIS; RADIOMETRY;

EID: 0343183095     PISSN: 03787966     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03190036     Document Type: Article

References (16)

1. Callingham B.A., Barrand M.A. (1987) : Some properties of semicarbazide-sensitive amine oxidases. J. Neural. Transm., 23 (Suppl.), 37-54.
2. Yu P.H., Zuo D.M. (1994) : Characterization of human serum and umbilical artery semicarbazide-sensitive amine oxidase (SSAO). Species heterogeneity and stereoisomeric specificity. Biochem. Pharmacol., 47, 1055-1059.
3. Lyles G.A. (1996) : Mammalian plasma and tissue-bound semicarbazide-sensitive amine oxidases: biochemical, pharmacological and toxicological aspects. Int. J. Biochem. Cell. Biol., 28, 259-274.
4. Raimondi L., Pirisino R., Banchelli G. et al. (1992) : Further studies on semicarbazide-sensitive amine oxidase activities (SSAO) of white adipose tissue. Comp. Biochem. Physiol. B, 102, 953-960.
5. 2-generating system present in human fat cell plasma membranes is multireceptor-linked and under antagonistic control by hormones and cytokines. Biochem. J., 307, 543-548.
6. Yu P.H., Zuo D.M. (1993) : Oxidative deamination of methylamine by semicarbazide-sensitive amine oxidase leads to cytotoxic damage in endothelial cells - possible consequences for diabetes. Diabetes, 42, 594-603.
7. Yu P.H., Zuo D.M. (1996) : Formaldehyde produced endogenously via deamination of methylamine. A potential risk factor for initiation of endothelial injury. Atherosclerosis, 120, 189-197
8. Boomsma F., van Veldhuisen D.J., de Kam P.J. et al. (1997) : Plasma semicarbazide-sensitive amine oxidase is elevated in patients with congestive heart failure. Cardiovasc. Res., 33, 387-391.
9. Boomsma F., Derkx F.H., van den Meiracker A.H., Man in't Veld A.J., Schalekamp M.A. (1995) : Plasma semicarbazide-sensitive amine oxidase activity is elevated in diabetes mellitus and correlates with glycosylated haemoglobin. Clin. Sci. (Colch.), 88, 675-679.
10. Yu P.H., Zuo D.M. (1992) : Inhibition of a type B monoamine oxidase inhibitor, (E)-2-(4-fluorophenethyl)-3-fluoroallylamine (MDL-72974A), on semicarbazide sensitive amine oxidases isolated from vascular tissues and sera of different species. Biochem. Pharmacol., 43, 307-312.
11. Bradford M.M. (1976) : A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye-binding. Anal. Biochem., 72, 248-254.
12. Yu P.H. (1990) : Oxidative deamination of aliphatic amines by rat aorta semicarbazide-sensitive amine oxidase. J. Pharm. Pharmacol., 42, 882-884.
13. Lyles G.A., Holt A., Marshal C.M.S. (1990) : Further studies on the metabolism of methylamine by semicarbazide sensitive amine oxidase activities in human plasma, umbilical artery and rat aorta. J. Pharm. Pharmacol., 42, 322-338.
14. North American Symptomatic Carotid Endarterectomy Trial Collaborators (1991) : Beneficial effect of carotid endarterectomy in symptomatic patients until length-grade carotid stenosis. N. Engl. J. Med., 325, 445-453.
15. King G.L. (1996) : The role of hyperglycaemia and hyperinsulinaemia in causing vascular dysfunction in diabetes. Ann. Med., 28, 427-432.
16. Stehouwer C.D.A., Lambert J., Donker A.J.M., van Hinsbergh V.W.M. (1997) : Endothelial dysfunction and pathogenesis of diabetic angiopathy. Cardiovasc. Res., 34, 55-68.