Mutational Analysis and Reconstituted Expression of the Biosynthetic Genes Involved in the Formation of 3-Amino-5-hydroxybenzoic Acid, the Starter Unit of Rifamycin Biosynthesis in Amycolatopsis mediterranei S699

Journal of Biological Chemistry

Volumn 276, Issue 16, 2001, Pages 12546-12555

  Yu, Tin Wein ^a   Müller, Rolf ^a,c   Müller, Michael ^a,d   Zhang, Xiaohong ^a   Draeger, Gerald ^a,e   Kim, Chun Gyu ^a,f   Leistner, Eckhard ^b   Floss, Heinz G ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF BONN   (Germany)

^c HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^d FORSCHUNGSZENTRUM JÜLICH   (Germany)

^e LEIBNIZ UNIVERSITY HANNOVER   (Germany)

^f Inje University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BENZENE; BIOSYNTHESIS; CATALYSIS; GENETIC ENGINEERING; MUTAGENESIS;

GENE ENCODING;

BIOCHEMISTRY;

3 AMINO 5 HYDROXYBENZOIC; 3 AMINO 5 HYDROXYBENZOIC ACID; 3,4 DIDEOXY 4 AMINO DEXTRO ARABINOHEPTULOSONATE 7 PHOSPHATE; ANSAMYCIN DERIVATIVE; BENZOIC ACID DERIVATIVE; ERYTHROSE 4 PHOSPHATE; GENE PRODUCT; PHOSPHATE; PHOSPHOENOLPYRUVATE; RIFAMYCIN; SHIKIMIC ACID; UNCLASSIFIED DRUG; 3-AMINO-5-HYDROXYBENZOIC ACID; AMINOBENZOIC ACID DERIVATIVE; PRIMER DNA; RIFABUTIN;

AMYCOLAPTOSIS MEDITERRANEI; ARTICLE; BIOSYNTHESIS; CELL FREE SYSTEM; DRUG SYNTHESIS; FERMENTATION; FUNGAL GENE; GENE DELETION; GENE EXPRESSION; GENE INACTIVATION; GENETIC CODE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; RIFG GENE; RIFH GENE; RIFJ GENE; RIFL GENE; RIFM GENE; RIFN GENE; SITE DIRECTED MUTAGENESIS; STREPTOMYCES COELICOLOR; ACTINOMYCETALES; AMINO ACID SEQUENCE; BACTERIAL GENE; ENZYMOLOGY; GENETICS; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; MULTIGENE FAMILY; OPEN READING FRAME; PLASMID; REGULATOR GENE; RESTRICTION MAPPING;

AMYCOLATOPSIS; AMYCOLATOPSIS MEDITERRANEI; STREPTOMYCES; STREPTOMYCES COELICOLOR;

ACTINOMYCETALES; AMINO ACID SEQUENCE; AMINOBENZOIC ACIDS; BASE SEQUENCE; DNA MUTATIONAL ANALYSIS; DNA PRIMERS; GENES, BACTERIAL; GENES, REGULATOR; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; OPEN READING FRAMES; PLASMIDS; PROMOTER REGIONS (GENETICS); RESTRICTION MAPPING; RIFABUTIN; RIFAMYCINS;

EID: 0035918169     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009667200     Document Type: Article

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