Structural insight into the inhibition of acetylcholinesterase by 2,3,4, 5-tetrahydro-1, 5-benzothiazepines

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 23, Issue 2, 2008, Pages 206-212

  Nawaz, Sarfraz A ^a   Umbreen, Sumaira ^b   Kahlid, Asaad ^a   Ansari, Farzana L ^b   Choudhary, M Iqbal ^a  

^a UNIVERSITY OF KARACHI   (Pakistan)

^b QUAID I AZAM UNIVERSITY   (Pakistan)

Author keywords

Acetylcholinesterase inhibition; Benzothiazepines; Molecular docking

Indexed keywords

2,3,4,5 TETRAHYDRO 1,5 BENZOTHIAZEPINE; BENZOTHIAZEPINE DERIVATIVE; CHOLINESTERASE INHIBITOR; GALANTAMINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONCENTRATION RESPONSE; DRUG DESIGN; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME INHIBITION; HYDROGEN BOND; HYDROPHOBICITY; IC 50; LIGAND BINDING; LINEAR REGRESSION ANALYSIS; MOLECULAR DOCKING; PRIORITY JOURNAL; STEADY STATE;

ACETYLCHOLINESTERASE; BINDING SITES; CHOLINESTERASE INHIBITORS; HYDROGEN; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZEPINES;

EID: 40949135271     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756360701533080     Document Type: Article

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