Fetal haemoglobin response to hydroxycarbamide treatment and sar1a promoter polymorphisms in sickle cell anaemia

British Journal of Haematology

Volumn 141, Issue 2, 2008, Pages 254-259

  Kumkhaek, Chutima ^a   Taylor VI, James G ^b   Zhu, Jianqiong ^a   Hoppe, Carolyn ^c   Kato, Gregory J ^b,d   Rodgers, Griffin P ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c CHILDREN S HOSPITAL OAKLAND   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Fetal haemoglobin; Hydroxycarbamide; SAR1A; Sickle cell disease; Single nucleotide polymorphism

Indexed keywords

HEMOGLOBIN F; HYDROXYUREA; PROTEIN DERIVATIVE; SECRETION ASSOCIATED AND RAS RELATED 1A PROTEIN; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ADULT; ARTICLE; CLINICAL TRIAL; DNA SEQUENCE; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; NEWBORN; NEWBORN SCREENING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN POLYMORPHISM; REGULATORY SEQUENCE; SICKLE CELL ANEMIA; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT DURATION; TREATMENT RESPONSE;

ADULT; ANEMIA, SICKLE CELL; ANTISICKLING AGENTS; FETAL HEMOGLOBIN; HUMANS; HYDROXYUREA; INFANT, NEWBORN; MONOMERIC GTP-BINDING PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS);

EID: 40949133859     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2008.07045.x     Document Type: Article

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