Both the N-terminal fragment and the protein-protein interaction domain (PDZ domain) are required for the pro-apoptotic activity of presenilin-associated protein PSAP

Biochimica et Biophysica Acta - General Subjects

Volumn 1780, Issue 4, 2008, Pages 696-708

  Mao, Guozhang ^a   Tan, Jianxin ^a   Gao, Wei ^a   Shi, Yongchang ^a   Cui, Mei Zhen ^a   Xu, Xuemin ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

Author keywords

Alzheimer's disease; Apoptosis; Caspase; Cell death; Cytochrome c; Mitochondria

Indexed keywords

ADENOSINE; ANTIBODY; CASPASE; CYTOCHROME C; GUANINE; ISOPROTEIN; PDZ PROTEIN; PRESENILIN; PRESENILIN ASSOCIATED PROTEIN; PROTEIN; THYMINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CHROMOSOME 6; CODON; CONTROLLED STUDY; EXON; GENE; GENE LOCATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PSAP GENE;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BASE SEQUENCE; CELL LINE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 6; CHYMOTRYPSIN; CODON, INITIATOR; ENDOPEPTIDASE K; EXONS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTRONS; MEMBRANE PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; PDZ DOMAINS; PROTEIN BINDING; PROTEIN ISOFORMS; TRYPSIN;

EID: 40949133264     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2008.01.013     Document Type: Article

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